4MHQA

Crystal structure of human primase catalytic subunit
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
419
structure length
400
Chain Sequence
METFDPTELPELLKLYYRRLFPYSQYYRWLNYGGVIKNYFQHREFSFTLKDDIYIRYQSFNNQSDLEKEMQKMNPYKIDIGAVYSHRPNQHNTVKLGAFQAQEKELVFDIDMTDYDDVRRCCSSADICPKCWTLMTMAIRIIDRALKEDFGFKHRLWVYSGRRGVHCWVCDESVRKLSSAVRSGIVEYLSLVKGGQDVKKKVHLSEKIHPFIRKSINIIKKYFEEYALVNQDILENKESWDKILALVPETIHDELQQSFQKSHNSLQRWEHLKKVASRYQNNIKNDKYGPWLEWEIMLQYCFPRLDINVSKGINHLLKSPFSVHPKTGRISVPIDLQKVDQFDPFTVPTISFICRELDAITRDYKKTSLAPYVKVFEHFLENLDKSRKGELLKKSDLQKD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Replication
molecule keywords DNA primase small subunit
publication title Crystal structure of human primase catalytic subunit
rcsb
source organism Homo sapiens
total genus 134
structure length 400
sequence length 419
ec nomenclature ec 2.7.7.-:
pdb deposition date 2013-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01896 DNA_primase_S DNA primase small subunit
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.920.30 Alpha Beta Alpha-Beta Complex DNA primase, PRIM domain DNA primase, PRIM domain 4mhqA00
4LIMA 4RR2A 2FAOA 1ZT2A 5EXRA 4MHQA 4BPXA 2FARA 4MM2A 4LILA 2FAQA 4BPUA 4LIKA 4BPWA
chains in the Genus database with same CATH superfamily
4LIMA 4RR2A 2FAOA 1ZT2A 5EXRA 4MHQA 4BPXA 4BPWA 1G71A 2FARA 1V33A 4MM2A 4LILA 2FAQA 4BPUA 4LIKA 2ATZA 1V34A
chains in the Genus database with same CATH topology
4LIMA 4RR2A 2FAOA 1ZT2A 5EXRA 4MHQA 4BPXA 4BPWA 1G71A 2FARA 1V33A 4LILA 2FAQA 4BPUA 4LIKA 4MM2A 1V34A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LIM A;  4RR2 A;  2FAO A;  1ZT2 A;  5EXR A;  4MHQ A;  4BPX A;  2FAR A;  4MM2 A;  4LIL A;  2FAQ A;  4BPU A;  4LIK A;  4BPW A; 
#chains in the Genus database with same CATH topology
 4LIM A;  4RR2 A;  2FAO A;  1ZT2 A;  5EXR A;  4MHQ A;  4BPX A;  4BPW A;  1G71 A;  2FAR A;  1V33 A;  4MM2 A;  4LIL A;  2FAQ A;  4BPU A;  4LIK A;  2ATZ A;  1V34 A; 
#chains in the Genus database with same CATH homology
 4LIM A;  4RR2 A;  2FAO A;  1ZT2 A;  5EXR A;  4MHQ A;  4BPX A;  4BPW A;  1G71 A;  2FAR A;  1V33 A;  4LIL A;  2FAQ A;  4BPU A;  4LIK A;  4MM2 A;  1V34 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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