4N7GA

Crystal structure of 14-3-3zeta in complex with a peptide derived from exos
Total Genus 107
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
107
sequence length
230
structure length
229
Chain Sequence
MDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELTLSEESYKDSTLIMQLLRDNLTLWTS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords 14-3-3 protein zeta/delta
total genus 107
structure length 229
sequence length 230
ec nomenclature
pdb deposition date 2013-10-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00244 14-3-3 14-3-3 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.190.20 Mainly Alpha Up-down Bundle Delta-Endotoxin; domain 1 14-3-3 domain 4n7gA00
4DHRA 3P1OA 2V7DA 2O02A 4Y5IA 2B05A 4DHUA 3U9XA 1IB1A 3E6YA 4WRQA 2O98A 4IEAA 4DATA 3P1NA 4F7RA 5BY9A 2C23A 4N84A 5D3EA 5D2DA 4FR3A 3SMLA 4O46A 3IQUA 3AXYC 4Y32A 5HF3A 3IQJA 1QJAA 1YWTA 4J6SA 4DHTA 3T0LA 3P1SA 4E2EA 3UALA 3P1PA 3SMNA 5LHOA 4N7YA 2C74A 4DHMA 4JDDA 2WH0A 4HKCA 1A38A 4JC3A 2BR9A 4FJ3A 3UZDA 3UX0A 4ZQ0A 2NPMA 3SMMA 4ZDRA 1O9DA 2C63A 4DNKA 4BG6A 3UBWA 5LU1A 5IQPA 3NKXA 3M51A 3P1QA 1O9FA 2BQ0A 4QLIA 4DX0A 4DAUA 2O8PA 3SP5A 4FL5A 5F74A 1QJBA 5EWZA 1A37A 5J31A 2C1JA 5LX2A 3IQVA 4DHPA 5D3FA 5LU2A 1YZ5A 3MHRA 1O9EA 3SPRA 2BTPA 3LW1A 3RDHA 4DHNA 2C1NA 4N7GA 4DHSA 4DHOA 3EFZA 3O8IA 4IHLA 3M50A 3P1RA 3SMOA 1O9CA 3CU8A 4Y3BA 5BTVA 4DHQA 5LVZA 3T0MA 1A4OA 4GNTA 5EXAA 3SMKA
chains in the Genus database with same CATH superfamily
4DHRA 3P1OA 2V7DA 2O02A 4Y5IA 2B05A 4DHUA 1S2XA 3U9XA 1IB1A 3E6YA 1W99A 4WRQA 2O98A 4IEAA 4DATA 3P1NA 1CIYA 1URJA 3EB7A 4F7RA 5BY9A 2C23A 3CQGA 1I5PA 4N84A 5D3EA 3CQCA 5D2DA 4FR3A 3SMLA 4O46A 3IQUA 3AXYC 4Y32A 5HF3A 3IQJA 1QJAA 1YWTA 4J6SA 4DHTA 4QX2A 4MOAA 3T0LA 3X0UA 3P1SA 4E2EA 3UALA 3P1PA 3SMNA 4QX1A 5LHOA 4N7YA 2C74A 4DHMA 4JDDA 4QX3A 2WH0A 4HKCA 1A38A 4QX0A 4JC3A 2BR9A 4D8MA 4FJ3A 3UZDA 3UX0A 4ZQ0A 2NPMA 1DLCA 3SMMA 4ZDRA 1O9DA 2C63A 4DNKA 4BG6A 3UBWA 5LU1A 5IQPA 3I4RA 3M51A 3NKXA 3P1QA 1O9FA 2BQ0A 4ARXA 4ARYA 4QLIA 2C9KA 4DX0A 4DAUA 2O8PA 3SP5A 4FL5A 5F74A 1QJBA 5EWZA 1A37A 5J31A 2C1JA 5LX2A 3IQVA 4DHPA 3ZHEB 5D3FA 5LU2A 1YZ5A 3MHRA 1O9EA 3SPRA 2BTPA 3LW1A 3RDHA 4DHNA 2C1NA 4N7GA 4DHSA 4DHOA 3EFZA 3O8IA 4IHLA 1JI6A 3M50A 3P1RA 3SMOA 1O9CA 3CU8A 4W8JA 4Y3BA 5BTVA 4DHQA 5LVZA 3T0MA 1A4OA 4GNTA 5EXAA 3SMKA
chains in the Genus database with same CATH topology
4DHRA 3P1OA 2V7DA 2O02A 4Y5IA 2B05A 4DHUA 3U9XA 1IB1A 3E6YA 4WRQA 2O98A 4IEAA 4DATA 3P1NA 4F7RA 5BY9A 2C23A 4N84A 5D3EA 5D2DA 4FR3A 3SMLA 4O46A 3IQUA 3AXYC 4Y32A 5HF3A 3IQJA 1QJAA 1YWTA 4J6SA 4DHTA 3T0LA 3P1SA 4E2EA 3UALA 3P1PA 3SMNA 5LHOA 4N7YA 2C74A 4DHMA 4JDDA 2WH0A 4HKCA 1A38A 4JC3A 2BR9A 4FJ3A 3UZDA 3UX0A 4ZQ0A 2NPMA 3SMMA 4ZDRA 1O9DA 2C63A 4DNKA 4BG6A 3UBWA 5LU1A 5IQPA 3NKXA 3M51A 3P1QA 1O9FA 2BQ0A 4QLIA 4DX0A 4DAUA 2O8PA 3SP5A 4FL5A 5F74A 1QJBA 5EWZA 1A37A 5J31A 2C1JA 5LX2A 3IQVA 4DHPA 5D3FA 5LU2A 1YZ5A 3MHRA 1O9EA 3SPRA 2BTPA 3LW1A 3RDHA 4DHNA 2C1NA 4N7GA 4DHSA 4DHOA 3EFZA 3O8IA 4IHLA 3M50A 3P1RA 3SMOA 1O9CA 3CU8A 4Y3BA 5BTVA 4DHQA 5LVZA 3T0MA 1A4OA 4GNTA 5EXAA 3SMKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4DHR A;  3P1O A;  2V7D A;  2O02 A;  4Y5I A;  2B05 A;  4DHU A;  3U9X A;  1IB1 A;  3E6Y A;  4WRQ A;  2O98 A;  4IEA A;  4DAT A;  3P1N A;  4F7R A;  5BY9 A;  2C23 A;  4N84 A;  5D3E A;  5D2D A;  4FR3 A;  3SML A;  4O46 A;  3IQU A;  3AXY C;  4Y32 A;  5HF3 A;  3IQJ A;  1QJA A;  1YWT A;  4J6S A;  4DHT A;  3T0L A;  3P1S A;  4E2E A;  3UAL A;  3P1P A;  3SMN A;  5LHO A;  4N7Y A;  2C74 A;  4DHM A;  4JDD A;  2WH0 A;  4HKC A;  1A38 A;  4JC3 A;  2BR9 A;  4FJ3 A;  3UZD A;  3UX0 A;  4ZQ0 A;  2NPM A;  3SMM A;  4ZDR A;  1O9D A;  2C63 A;  4DNK A;  4BG6 A;  3UBW A;  5LU1 A;  5IQP A;  3NKX A;  3M51 A;  3P1Q A;  1O9F A;  2BQ0 A;  4QLI A;  4DX0 A;  4DAU A;  2O8P A;  3SP5 A;  4FL5 A;  5F74 A;  1QJB A;  5EWZ A;  1A37 A;  5J31 A;  2C1J A;  5LX2 A;  3IQV A;  4DHP A;  5D3F A;  5LU2 A;  1YZ5 A;  3MHR A;  1O9E A;  3SPR A;  2BTP A;  3LW1 A;  3RDH A;  4DHN A;  2C1N A;  4N7G A;  4DHS A;  4DHO A;  3EFZ A;  3O8I A;  4IHL A;  3M50 A;  3P1R A;  3SMO A;  1O9C A;  3CU8 A;  4Y3B A;  5BTV A;  4DHQ A;  5LVZ A;  3T0M A;  1A4O A;  4GNT A;  5EXA A;  3SMK A; 
#chains in the Genus database with same CATH topology
 4DHR A;  3P1O A;  2V7D A;  2O02 A;  4Y5I A;  2B05 A;  4DHU A;  1S2X A;  3U9X A;  1IB1 A;  3E6Y A;  1W99 A;  4WRQ A;  2O98 A;  4IEA A;  4DAT A;  3P1N A;  1CIY A;  1URJ A;  3EB7 A;  4F7R A;  5BY9 A;  2C23 A;  3CQG A;  1I5P A;  4N84 A;  5D3E A;  3CQC A;  5D2D A;  4FR3 A;  3SML A;  4O46 A;  3IQU A;  3AXY C;  4Y32 A;  5HF3 A;  3IQJ A;  1QJA A;  1YWT A;  4J6S A;  4DHT A;  4QX2 A;  4MOA A;  3T0L A;  3X0U A;  3P1S A;  4E2E A;  3UAL A;  3P1P A;  3SMN A;  4QX1 A;  5LHO A;  4N7Y A;  2C74 A;  4DHM A;  4JDD A;  4QX3 A;  2WH0 A;  4HKC A;  1A38 A;  4QX0 A;  4JC3 A;  2BR9 A;  4D8M A;  4FJ3 A;  3UZD A;  3UX0 A;  4ZQ0 A;  2NPM A;  1DLC A;  3SMM A;  4ZDR A;  1O9D A;  2C63 A;  4DNK A;  4BG6 A;  3UBW A;  5LU1 A;  5IQP A;  3I4R A;  3M51 A;  3NKX A;  3P1Q A;  1O9F A;  2BQ0 A;  4ARX A;  4ARY A;  4QLI A;  2C9K A;  4DX0 A;  4DAU A;  2O8P A;  3SP5 A;  4FL5 A;  5F74 A;  1QJB A;  5EWZ A;  1A37 A;  5J31 A;  2C1J A;  5LX2 A;  3IQV A;  4DHP A;  3ZHE B;  5D3F A;  5LU2 A;  1YZ5 A;  3MHR A;  1O9E A;  3SPR A;  2BTP A;  3LW1 A;  3RDH A;  4DHN A;  2C1N A;  4N7G A;  4DHS A;  4DHO A;  3EFZ A;  3O8I A;  4IHL A;  1JI6 A;  3M50 A;  3P1R A;  3SMO A;  1O9C A;  3CU8 A;  4W8J A;  4Y3B A;  5BTV A;  4DHQ A;  5LVZ A;  3T0M A;  1A4O A;  4GNT A;  5EXA A;  3SMK A; 
#chains in the Genus database with same CATH homology
 4DHR A;  3P1O A;  2V7D A;  2O02 A;  4Y5I A;  2B05 A;  4DHU A;  3U9X A;  1IB1 A;  3E6Y A;  4WRQ A;  2O98 A;  4IEA A;  4DAT A;  3P1N A;  4F7R A;  5BY9 A;  2C23 A;  4N84 A;  5D3E A;  5D2D A;  4FR3 A;  3SML A;  4O46 A;  3IQU A;  3AXY C;  4Y32 A;  5HF3 A;  3IQJ A;  1QJA A;  1YWT A;  4J6S A;  4DHT A;  3T0L A;  3P1S A;  4E2E A;  3UAL A;  3P1P A;  3SMN A;  5LHO A;  4N7Y A;  2C74 A;  4DHM A;  4JDD A;  2WH0 A;  4HKC A;  1A38 A;  4JC3 A;  2BR9 A;  4FJ3 A;  3UZD A;  3UX0 A;  4ZQ0 A;  2NPM A;  3SMM A;  4ZDR A;  1O9D A;  2C63 A;  4DNK A;  4BG6 A;  3UBW A;  5LU1 A;  5IQP A;  3NKX A;  3M51 A;  3P1Q A;  1O9F A;  2BQ0 A;  4QLI A;  4DX0 A;  4DAU A;  2O8P A;  3SP5 A;  4FL5 A;  5F74 A;  1QJB A;  5EWZ A;  1A37 A;  5J31 A;  2C1J A;  5LX2 A;  3IQV A;  4DHP A;  5D3F A;  5LU2 A;  1YZ5 A;  3MHR A;  1O9E A;  3SPR A;  2BTP A;  3LW1 A;  3RDH A;  4DHN A;  2C1N A;  4N7G A;  4DHS A;  4DHO A;  3EFZ A;  3O8I A;  4IHL A;  3M50 A;  3P1R A;  3SMO A;  1O9C A;  3CU8 A;  4Y3B A;  5BTV A;  4DHQ A;  5LVZ A;  3T0M A;  1A4O A;  4GNT A;  5EXA A;  3SMK A; 
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