4NBPA

Crystal structure of the jcv large t-antigen origin binding domain
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
129
structure length
129
Chain Sequence
VEDPKDFPVDLHAFLSQAVFSNRTVASFAVYTTKEKAQILYKKLMEKYSVTFISRHGFGGHNILFFLTPHRHRVSAINNYCQKLCTFSFLICKGVNKEYLFYSALCRQPYAVVEESIQGGLKEHDFNPE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Hydrolase
molecule keywords Large T antigen
publication title Insights into the Initiation of JC Virus DNA Replication Derived from the Crystal Structure of the T-Antigen Origin Binding Domain.
pubmed doi rcsb
source organism Jc polyomavirus
total genus 35
structure length 129
sequence length 129
ec nomenclature ec 3.6.4.-:
pdb deposition date 2013-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02217 T_Ag_DNA_bind Origin of replication binding protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1310.20 Alpha Beta 3-Layer(aba) Sandwich Replication Protein E1; Chain: A, Replication Protein E1; Chain: A, 4nbpA00
1Z1DB 1M55A 4FB3A 4LMDA 2TBDA 2IF9A 2NTCA 1L5IA 3QN2A 5CYNA 3QFQA 4ZQ9A 4LIFA 5BYGA 4FGNA 2NL8A 3QK2A 5D9IA 5DCXA 1UUTA 4GDFA 2HW0A 2FUFA 1TBDA 2IPRA 1RZ9A 4NBPA 2ITLA 4ZO0A 2ITJA 1L2MA
chains in the Genus database with same CATH superfamily
1L2MA 1Z1DB 1M55A 4FB3A 4LMDA 2TBDA 1KSXA 2IF9A 1R9WA 2NTCA 1L5IA 3QN2A 5CYNA 3QFQA 4ZQ9A 4LIFA 1F08A 5BYGA 3DKYA 4FGNA 2NL8A 3QK2A 4U87A 5D9IA 5DCXA 1UUTA 4GDFA 1KSYA 2HW0A 3DKXA 2FUFA 1TBDA 2IPRA 1RZ9A 4NBPA 2ITLA 4ZO0A 2ITJA 4KW3A
chains in the Genus database with same CATH topology
1L2MA 1Z1DB 1M55A 4FB3A 4LMDA 2TBDA 1KSXA 2IF9A 1R9WA 2NTCA 1L5IA 3QN2A 5CYNA 3QFQA 4ZQ9A 4LIFA 1F08A 5BYGA 3DKYA 4FGNA 2NL8A 3QK2A 4U87A 5D9IA 5DCXA 1UUTA 4GDFA 1KSYA 2HW0A 3DKXA 2FUFA 1TBDA 2IPRA 1RZ9A 4NBPA 2ITLA 4ZO0A 2ITJA 4KW3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1Z1D B;  1M55 A;  4FB3 A;  4LMD A;  2TBD A;  2IF9 A;  2NTC A;  1L5I A;  3QN2 A;  5CYN A;  3QFQ A;  4ZQ9 A;  4LIF A;  5BYG A;  4FGN A;  2NL8 A;  3QK2 A;  5D9I A;  5DCX A;  1UUT A;  4GDF A;  2HW0 A;  2FUF A;  1TBD A;  2IPR A;  1RZ9 A;  4NBP A;  2ITL A;  4ZO0 A;  2ITJ A;  1L2M A; 
#chains in the Genus database with same CATH topology
 1L2M A;  1Z1D B;  1M55 A;  4FB3 A;  4LMD A;  2TBD A;  1KSX A;  2IF9 A;  1R9W A;  2NTC A;  1L5I A;  3QN2 A;  5CYN A;  3QFQ A;  4ZQ9 A;  4LIF A;  1F08 A;  5BYG A;  3DKY A;  4FGN A;  2NL8 A;  3QK2 A;  4U87 A;  5D9I A;  5DCX A;  1UUT A;  4GDF A;  1KSY A;  2HW0 A;  3DKX A;  2FUF A;  1TBD A;  2IPR A;  1RZ9 A;  4NBP A;  2ITL A;  4ZO0 A;  2ITJ A;  4KW3 A; 
#chains in the Genus database with same CATH homology
 1L2M A;  1Z1D B;  1M55 A;  4FB3 A;  4LMD A;  2TBD A;  1KSX A;  2IF9 A;  1R9W A;  2NTC A;  1L5I A;  3QN2 A;  5CYN A;  3QFQ A;  4ZQ9 A;  4LIF A;  1F08 A;  5BYG A;  3DKY A;  4FGN A;  2NL8 A;  3QK2 A;  4U87 A;  5D9I A;  5DCX A;  1UUT A;  4GDF A;  1KSY A;  2HW0 A;  3DKX A;  2FUF A;  1TBD A;  2IPR A;  1RZ9 A;  4NBP A;  2ITL A;  4ZO0 A;  2ITJ A;  4KW3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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