4NBXA

Crystal structure of clostridium difficile toxin a fragment tcda-a1 bound to a20.1 vhh
Total Genus 25
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
25
sequence length
143
structure length
143
Chain Sequence
HHHHHHTGWVTIDGRRYYFEPNTAIGANGYKIIDNKNFYFRNGLPQIGVFKGPNGFEYFAPANTDANNIDGQAIRYQNRFLHLLGNIYYFGNNSKAVTGWQTINGNMYYFMPDTAMAAAGGLFEIDGVIYFFGVDGVKAPGIY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Antibody Recognition in the Receptor-binding Domains of Toxins A and B from Clostridium difficile.
pubmed doi rcsb
molecule tags Immune system
source organism Clostridium difficile
molecule keywords TcdA
total genus 25
structure length 143
sequence length 143
ec nomenclature
pdb deposition date 2013-10-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01473 CW_binding_1 Putative cell wall binding repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.270.10 Mainly Beta Ribbon left handed beta-beta-3-solenoid Cholin Binding 4nbxA00
1H8GA 2F6EA 3KLLA 2J8GA 4TVDA 4X36A 1H09A 2X8PA 4TVCA 2QJ6A 3KLKA 4TTUA 1GVMA 3TTQA 4NBYA 3HZ3A 3TTOA 2IXVA 2IXUA 2J8FA 3HIAA 4NBXA 4AYGA 2G7CA 2X8OA 1OBAA 4NC2A 4NC0A 2X8MA 2V04A 2VYUA 4NBZA 2BMLA 2V05A 1HCXA
chains in the Genus database with same CATH superfamily
1H8GA 2F6EA 3KLLA 2J8GA 4TVDA 4X36A 1H09A 2X8PA 4TVCA 2QJ6A 3KLKA 4TTUA 1GVMA 3TTQA 4NBYA 3HZ3A 3TTOA 2IXVA 2IXUA 2J8FA 3HIAA 4NBXA 4AYGA 2G7CA 2X8OA 1OBAA 4NC2A 4NC0A 2X8MA 2V04A 2VYUA 4NBZA 2BMLA 2V05A 1HCXA
chains in the Genus database with same CATH topology
1H8GA 2F6EA 3KLLA 2J8GA 4TVDA 4X36A 1H09A 2X8PA 4TVCA 2QJ6A 3KLKA 4TTUA 1GVMA 3TTQA 4NBYA 3HZ3A 3TTOA 2IXVA 2IXUA 2J8FA 3HIAA 4NBXA 4AYGA 2G7CA 2X8OA 1OBAA 4NC2A 4NC0A 2X8MA 2V04A 2VYUA 4NBZA 2BMLA 2V05A 1HCXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1H8G A;  2F6E A;  3KLL A;  2J8G A;  4TVD A;  4X36 A;  1H09 A;  2X8P A;  4TVC A;  2QJ6 A;  3KLK A;  4TTU A;  1GVM A;  3TTQ A;  4NBY A;  3HZ3 A;  3TTO A;  2IXV A;  2IXU A;  2J8F A;  3HIA A;  4NBX A;  4AYG A;  2G7C A;  2X8O A;  1OBA A;  4NC2 A;  4NC0 A;  2X8M A;  2V04 A;  2VYU A;  4NBZ A;  2BML A;  2V05 A;  1HCX A; 
#chains in the Genus database with same CATH topology
 1H8G A;  2F6E A;  3KLL A;  2J8G A;  4TVD A;  4X36 A;  1H09 A;  2X8P A;  4TVC A;  2QJ6 A;  3KLK A;  4TTU A;  1GVM A;  3TTQ A;  4NBY A;  3HZ3 A;  3TTO A;  2IXV A;  2IXU A;  2J8F A;  3HIA A;  4NBX A;  4AYG A;  2G7C A;  2X8O A;  1OBA A;  4NC2 A;  4NC0 A;  2X8M A;  2V04 A;  2VYU A;  4NBZ A;  2BML A;  2V05 A;  1HCX A; 
#chains in the Genus database with same CATH homology
 1H8G A;  2F6E A;  3KLL A;  2J8G A;  4TVD A;  4X36 A;  1H09 A;  2X8P A;  4TVC A;  2QJ6 A;  3KLK A;  4TTU A;  1GVM A;  3TTQ A;  4NBY A;  3HZ3 A;  3TTO A;  2IXV A;  2IXU A;  2J8F A;  3HIA A;  4NBX A;  4AYG A;  2G7C A;  2X8O A;  1OBA A;  4NC2 A;  4NC0 A;  2X8M A;  2V04 A;  2VYU A;  4NBZ A;  2BML A;  2V05 A;  1HCX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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