4NE5B

Human mhf1-mhf2 complex
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
74
structure length
74
Chain Sequence
SGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Dna binding protein
molecule keywords Centromere protein S
publication title The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes.
pubmed doi rcsb
source organism Homo sapiens
total genus 22
structure length 74
sequence length 74
chains with identical sequence D, F, H
ec nomenclature
pdb deposition date 2013-10-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF09415 CENP-X CENP-S associating Centromere protein X
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.286.100 Mainly Alpha Orthogonal Bundle GTP Cyclohydrolase I; Chain A, domain 1 GTP Cyclohydrolase I; Chain A, domain 1 4ne5B02
4NE6B 4NE5B 4NE3B 4E44B 3B0BC 4DRAE 4DRBJ 4E45B
chains in the Genus database with same CATH superfamily
2WSFK 4NE6B 4NE5B 2LO0A 2LNZA 1EL6A 2PN0A 1GTPA 1IS7A 5DMZA 1AIPC 1A8RA 1WPLA 1WM9A 3LW5G 3BMBA 1TFEA 4NE3B 2WSCG 4QPMA 2WSEG 3B0BC 1EFUB 4DRAE 3VEJA 4DRBJ 4E45B 2O01G 1FBXA 2P11A 4Q7JA 1N3RA 1WUQA 2WSFG 1N3TA 4JA3A 2KR1A 1N3SA 1IS8A 3LW5K 4R8QA 2WSCK 4DU6A 4E44B 2WSEK 1A9CA 1WURA 1FB1A
chains in the Genus database with same CATH topology
4NE6B 4NE5B 2LO0A 2LNZA 1EL6A 2PN0A 1GTPA 1IS7A 5DMZA 1AIPC 1A8RA 1WPLA 1WM9A 3BMBA 1TFEA 4NE3B 4QPMA 3B0BC 1EFUB 4DRAE 3VEJA 4DRBJ 4E45B 1FBXA 2P11A 4Q7JA 1N3RA 1WUQA 1N3TA 4JA3A 2KR1A 1N3SA 1IS8A 4R8QA 4DU6A 4E44B 1A9CA 1WURA 1FB1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NE6 B;  4NE5 B;  4NE3 B;  4E44 B;  3B0B C;  4DRA E;  4DRB J;  4E45 B; 
#chains in the Genus database with same CATH topology
 2WSF K;  4NE6 B;  4NE5 B;  2LO0 A;  2LNZ A;  1EL6 A;  2PN0 A;  1GTP A;  1IS7 A;  5DMZ A;  1AIP C;  1A8R A;  1WPL A;  1WM9 A;  3LW5 G;  3BMB A;  1TFE A;  4NE3 B;  2WSC G;  4QPM A;  2WSE G;  3B0B C;  1EFU B;  4DRA E;  3VEJ A;  4DRB J;  4E45 B;  2O01 G;  1FBX A;  2P11 A;  4Q7J A;  1N3R A;  1WUQ A;  2WSF G;  1N3T A;  4JA3 A;  2KR1 A;  1N3S A;  1IS8 A;  3LW5 K;  4R8Q A;  2WSC K;  4DU6 A;  4E44 B;  2WSE K;  1A9C A;  1WUR A;  1FB1 A; 
#chains in the Genus database with same CATH homology
 4NE6 B;  4NE5 B;  2LO0 A;  2LNZ A;  1EL6 A;  2PN0 A;  1GTP A;  1IS7 A;  5DMZ A;  1AIP C;  1A8R A;  1WPL A;  1WM9 A;  3BMB A;  1TFE A;  4NE3 B;  4QPM A;  3B0B C;  1EFU B;  4DRA E;  3VEJ A;  4DRB J;  4E45 B;  1FBX A;  2P11 A;  4Q7J A;  1N3R A;  1WUQ A;  1N3T A;  4JA3 A;  2KR1 A;  1N3S A;  1IS8 A;  4R8Q A;  4DU6 A;  4E44 B;  1A9C A;  1WUR A;  1FB1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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