4NH5A

Structure of human dicer platform-paz-connector helix cassette in complex with 14-mer sirna having 5'-puu and uu-3' ends (2.55 angstrom resolution)
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
298
structure length
271
Chain Sequence
QPCYLYVIGMVLTTPLPDELNFRRRKLYPPEDTTRCFGILTAKPIPQIPHFPVYTRSGEVTISIELAASGFMLSLQMLELITRLHQYIFSHILRLEKYCVLPLNVVNSTLDIDFKFMEDIEKSEARIGIPSTKYTKETPFVFKLEDYQDAVIIPRYRNFDQPHRFYVADVYTDLTPLSKFPSPEYETFAEYYKTKYNLDLTNLNQPLLDVDHTSSRLNLLTPRHAEKRKAKWESLQNKQILVPELCAIHPIPASLWRKAVCLPSILYRLHC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title A Phosphate-Binding Pocket within the Platform-PAZ-Connector Helix Cassette of Human Dicer.
pubmed doi rcsb
molecule tags Hydrolase/rna
source organism Homo sapiens
molecule keywords Endoribonuclease Dicer
total genus 67
structure length 271
sequence length 298
ec nomenclature ec 3.1.26.3: Ribonuclease III.
pdb deposition date 2013-11-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02170 PAZ PAZ domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.260.10 Mainly Beta Beta Complex paz domain paz domain 4nh5A02
5T7BA 1SI3A 4W5NA 1T2RA 4OLAA 3O6EX 4NGFA 4Z4HA 2QVWA 2L5CA 4W5QA 4W5TA 2FFLA 3MJ0A 3O7VX 4NHAA 4NGCA 3O7XA 4NGDA 3QIRA 4NH5A 5KI6A 4Z4EA 1VYNA 1R4KA 4NGGA 4W5RA 4Z4FA 4KREA 1SI2A 4OLBA 3O3IX 2L5DA 4Z4CA 4NH3A 4NGBA 4NH6A 4Z4IA 5JS2A 4W5OA 1T2SA 4F3TA 4KRFA 4Z4GA 2XFMA 1R6ZA 5JS1A
chains in the Genus database with same CATH superfamily
5T7BA 3HVRA 3HO1A 1SI3A 3HM9A 1T2RA 4OLAA 3O6EX 4W5NA 2DB9A 1Z25A 4NGFA 4Z4HA 2QVWA 2L5CA 4W5QA 4W5TA 2FFLA 3MJ0A 3O7VX 4L1PA 4NHAA 4NGCA 3O7XA 4NGDA 3HJFA 3QIRA 3HK2A 4NH5A 5KI6A 3F73A 3DLHA 4Z4EA 1VYNA 1R4KA 4NGGA 4W5RA 4Z4FA 1Z26A 1U04A 3DLBA 4KREA 1SI2A 4OLBA 3O3IX 2L5DA 4Z4CA 4NH3A 4NGBA 4NH6A 4L1UA 3U1UA 4Z4IA 5JS2A 3DA5A 2BZEA 4W5OA 1T2SA 4F3TA 4KRFA 4Z4GA 2XFMA 1R6ZA 5JS1A
chains in the Genus database with same CATH topology
5T7BA 3HVRA 3HO1A 1SI3A 3HM9A 1T2RA 4OLAA 3O6EX 4W5NA 2DB9A 1Z25A 4NGFA 4Z4HA 2QVWA 2L5CA 4W5QA 4W5TA 2FFLA 3MJ0A 3O7VX 4L1PA 4NHAA 4NGCA 3O7XA 4NGDA 3HJFA 3QIRA 3HK2A 4NH5A 5KI6A 3F73A 3DLHA 4Z4EA 1VYNA 1R4KA 4NGGA 4W5RA 4Z4FA 1Z26A 1U04A 3DLBA 4KREA 1SI2A 4OLBA 3O3IX 2L5DA 4Z4CA 4NH3A 4NGBA 4NH6A 4L1UA 3U1UA 4Z4IA 5JS2A 3DA5A 2BZEA 4W5OA 1T2SA 4F3TA 4KRFA 4Z4GA 2XFMA 1R6ZA 5JS1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5T7B A;  1SI3 A;  4W5N A;  1T2R A;  4OLA A;  3O6E X;  4NGF A;  4Z4H A;  2QVW A;  2L5C A;  4W5Q A;  4W5T A;  2FFL A;  3MJ0 A;  3O7V X;  4NHA A;  4NGC A;  3O7X A;  4NGD A;  3QIR A;  4NH5 A;  5KI6 A;  4Z4E A;  1VYN A;  1R4K A;  4NGG A;  4W5R A;  4Z4F A;  4KRE A;  1SI2 A;  4OLB A;  3O3I X;  2L5D A;  4Z4C A;  4NH3 A;  4NGB A;  4NH6 A;  4Z4I A;  5JS2 A;  4W5O A;  1T2S A;  4F3T A;  4KRF A;  4Z4G A;  2XFM A;  1R6Z A;  5JS1 A; 
#chains in the Genus database with same CATH topology
 5T7B A;  3HVR A;  3HO1 A;  1SI3 A;  3HM9 A;  1T2R A;  4OLA A;  3O6E X;  4W5N A;  2DB9 A;  1Z25 A;  4NGF A;  4Z4H A;  2QVW A;  2L5C A;  4W5Q A;  4W5T A;  2FFL A;  3MJ0 A;  3O7V X;  4L1P A;  4NHA A;  4NGC A;  3O7X A;  4NGD A;  3HJF A;  3QIR A;  3HK2 A;  4NH5 A;  5KI6 A;  3F73 A;  3DLH A;  4Z4E A;  1VYN A;  1R4K A;  4NGG A;  4W5R A;  4Z4F A;  1Z26 A;  1U04 A;  3DLB A;  4KRE A;  1SI2 A;  4OLB A;  3O3I X;  2L5D A;  4Z4C A;  4NH3 A;  4NGB A;  4NH6 A;  4L1U A;  3U1U A;  4Z4I A;  5JS2 A;  3DA5 A;  2BZE A;  4W5O A;  1T2S A;  4F3T A;  4KRF A;  4Z4G A;  2XFM A;  1R6Z A;  5JS1 A; 
#chains in the Genus database with same CATH homology
 5T7B A;  3HVR A;  3HO1 A;  1SI3 A;  3HM9 A;  1T2R A;  4OLA A;  3O6E X;  4W5N A;  2DB9 A;  1Z25 A;  4NGF A;  4Z4H A;  2QVW A;  2L5C A;  4W5Q A;  4W5T A;  2FFL A;  3MJ0 A;  3O7V X;  4L1P A;  4NHA A;  4NGC A;  3O7X A;  4NGD A;  3HJF A;  3QIR A;  3HK2 A;  4NH5 A;  5KI6 A;  3F73 A;  3DLH A;  4Z4E A;  1VYN A;  1R4K A;  4NGG A;  4W5R A;  4Z4F A;  1Z26 A;  1U04 A;  3DLB A;  4KRE A;  1SI2 A;  4OLB A;  3O3I X;  2L5D A;  4Z4C A;  4NH3 A;  4NGB A;  4NH6 A;  4L1U A;  3U1U A;  4Z4I A;  5JS2 A;  3DA5 A;  2BZE A;  4W5O A;  1T2S A;  4F3T A;  4KRF A;  4Z4G A;  2XFM A;  1R6Z A;  5JS1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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