4NTMA

Qued soaked with sepiapterin (selenomethionine substituted protein)
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
120
structure length
114
Chain Sequence
MMSTTLFKDFTFEAAHRLPHCGRLHGHSFMVRLEITGEVDPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLLSAVMVKETCTAGCIYRG
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Lyase
molecule keywords 6-carboxy-5,6,7,8-tetrahydropterin synthase
publication title Biochemical and Structural Studies of 6-Carboxy-5,6,7,8-tetrahydropterin Synthase Reveal the Molecular Basis of Catalytic Promiscuity within the Tunnel-fold Superfamily.
pubmed doi rcsb
source organism Escherichia coli
total genus 24
structure length 114
sequence length 120
chains with identical sequence B, C, D, E, F
ec nomenclature ec 4.1.2.50: 6-carboxytetrahydropterin synthase.
pdb deposition date 2013-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01242 PTPS 6-pyruvoyl tetrahydropterin synthase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.479.10 Alpha Beta 2-Layer Sandwich Tetrahydropterin Synthase; Chain A Tetrahydropterin Synthase; Chain A 4ntmA00
2A0SA 4NTKA 2DJ6A 3QN0A 4NTMA 1GTQA 3QNAA 2G64A 4NTNA 3LX3A 3D7JA 3M0NA 1Y13A 2DTTA 3LZEA 3QN9A 2OBAA 3JYGA 1B66A 1B6ZA 3I2BA
chains in the Genus database with same CATH superfamily
2A0SA 4NTKA 4FVFA 1AIPC 3BK6A 2DJ6A 3QN0A 4NTMA 1GTQA 3QNAA 2G64A 1TFEA 4NTNA 4FVJA 3LX3A 3D7JA 1XB2B 3M0NA 1Y13A 2DTTA 1WINA 3LZEA 4Q7JA 3QN9A 1EFUB 2RPBA 2OBAA 3JYGA 4FVGA 1B66A 1B6ZA 3I2BA
chains in the Genus database with same CATH topology
2A0SA 4NTKA 4FVFA 3BK6A 2DJ6A 3QN0A 4NTMA 1GTQA 3QNAA 2G64A 4NTNA 4FVJA 3LX3A 3D7JA 3M0NA 1Y13A 2DTTA 1WINA 3LZEA 3QN9A 2RPBA 2OBAA 3JYGA 4FVGA 1B66A 1B6ZA 3I2BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A0S A;  4NTK A;  2DJ6 A;  3QN0 A;  4NTM A;  1GTQ A;  3QNA A;  2G64 A;  4NTN A;  3LX3 A;  3D7J A;  3M0N A;  1Y13 A;  2DTT A;  3LZE A;  3QN9 A;  2OBA A;  3JYG A;  1B66 A;  1B6Z A;  3I2B A; 
#chains in the Genus database with same CATH topology
 2A0S A;  4NTK A;  4FVF A;  1AIP C;  3BK6 A;  2DJ6 A;  3QN0 A;  4NTM A;  1GTQ A;  3QNA A;  2G64 A;  1TFE A;  4NTN A;  4FVJ A;  3LX3 A;  3D7J A;  1XB2 B;  3M0N A;  1Y13 A;  2DTT A;  1WIN A;  3LZE A;  4Q7J A;  3QN9 A;  1EFU B;  2RPB A;  2OBA A;  3JYG A;  4FVG A;  1B66 A;  1B6Z A;  3I2B A; 
#chains in the Genus database with same CATH homology
 2A0S A;  4NTK A;  4FVF A;  3BK6 A;  2DJ6 A;  3QN0 A;  4NTM A;  1GTQ A;  3QNA A;  2G64 A;  4NTN A;  4FVJ A;  3LX3 A;  3D7J A;  3M0N A;  1Y13 A;  2DTT A;  1WIN A;  3LZE A;  3QN9 A;  2RPB A;  2OBA A;  3JYG A;  4FVG A;  1B66 A;  1B6Z A;  3I2B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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