4NWJA

Crystal structure of phosphopglycerate mutase from staphylococcus aureus in 3-phosphoglyceric acid bound form.
Total Genus 189
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
189
Knots found
sequence length
504
structure length
504
Chain Sequence
AKKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQIEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIAHVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSALKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKEGVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGFKVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHVTYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILNFANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDDQPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
publication title Complete catalytic cycle of cofactor-independent phosphoglycerate mutase involves a spring-loaded mechanism
pubmed doi rcsb
source organism Staphylococcus aureus subsp. aureus
molecule tags Isomerase
total genus 189
structure length 504
sequence length 504
other databases KnotProt 2.0: S +31
ec nomenclature ec 5.4.2.12: Phosphoglycerate mutase (2,3-diphosphoglycerate-independent).
pdb deposition date 2013-12-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01676 Metalloenzyme Metalloenzyme superfamily
A PF06415 iPGM_N BPG-independent PGAM N-terminus (iPGM_N)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 4nwjA01
3.40.1450.10 Alpha Beta 3-Layer(aba) Sandwich 2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain BPG-independent phosphoglycerate mutase, domain B 4nwjA02
1ALKA 4GTXA 3NKQA 5DLWA 3T01A 5L0EA 4LRDA 1URBA 1KH4A 3NKPA 4GTZA 5AJ9A 5INHA 2W5SA 3E2DA 3BDGA 2GLQA 3NKRA 1ANJA 4GTWA 3BDFA 3TX0A 3BDHA 4QAXA 3KD8A 1AJBA 4FDIA 3NKMA 3SZZA 1ALIA 5DLVA 3M8YA 4UPIA 5IJQA 1E3CP 2GA3A 2W5RA 2D1GA 3DPCA 5L0BA 3IDDA 4UPHA 4UOOA 3CMRA 1EW2A 4NWXA 2W5QA 1ALHA 3OT9A 4KAVA 2GSNA 3M8WA 1AUKA 1AJAA 3B5QA 2ANHA 2W5WA 1KH7A 4LQYA 3MK2A 2IFYA 2IUCB 1EI6A 4MY4A 2W5XA 2ZKTA 1SHNA 2XR9A 1Y6VA 1EW9A 2X98A 4UPKA 4TN0A 1K7HA 2W5TA 1ZEBA 3WAWA 5LIAA 4KM4A 3T00A 3NKNA 5K4PA 1ELZA 4GTYA 1ZEFA 2RH6A 1HDHA 5EGHA 4UPLA 4FDJA 3TG0A 2GSUA 1KHJA 2XRGA 3LXQA 1HQAA 1ALJA 4CYRA 5L0KA 1ED8A 4LR7A 4LREA 1FSUA 3DYCA 1KHLA 1N2LA 4CXKA 1ZEDA 5IJSA 3NKOA 1AJCA 1O99A 2W5VA 4NWJA 3IGZB 1ELXA 1KH5A 1B8JA 1N2KA 3SZYA 3WAYA 4MIVA 5LRMA 1ANIA 5EGEA 3BDGB 4N7TA 1Y7AA 3UN2A 1HJKA 4UOPA 4B56A 4ZGAA 2W8DA 4LRFA 3UN5A 5GOVA 5TJ3A 1EJJA 4UORA 1ED9A 3WAXA 5LRNA 1O98A 3A52A 1KHKA 2VQRA 5DLTA 5LQQA 4LR8A 2IUCA 4ZG6A 1EQJA 3T02A 1KHNA 4MHXA 1KH9A 2GSOA 2G9YA 4CXUA 4KJGA 3WAVA 4LRAA 3ED4A 4YR1A 1EW8A 4CXSA 4LRBA 3NVLA 3Q3QA 5C66A 5KXAA 5HRTA 2W8SA 1E2SP 1SHQA 1E1ZP 1ELYA 3UN3A 1AJDA 2QZUA 4CYSA 3IGYB 1E33P 3M8ZA 3M7VA 4LR9A 1P49A 4KJDA 3MK0A 4ZG7A 4ZG9A 4KAYA 3WBHA 3TWZA 3UO0A 3UNYA 3MK1A 4LR2A 4LRCA 5GRRA 1URAA
chains in the Genus database with same CATH superfamily
1ALKA 4GTXA 3NKQA 5DLWA 3T01A 5L0EA 4LRDA 1URBA 1KH4A 3NKPA 4GTZA 5AJ9A 5INHA 2W5SA 3E2DA 3BDGA 2GLQA 3NKRA 1ANJA 4GTWA 3BDFA 3TX0A 3BDHA 4QAXA 3KD8A 1AJBA 4FDIA 3NKMA 3SZZA 1ALIA 5DLVA 3M8YA 4UPIA 5IJQA 1E3CP 2GA3A 2W5RA 2D1GA 3DPCA 5L0BA 3IDDA 4UPHA 4UOOA 3CMRA 1EW2A 4NWXA 2W5QA 1ALHA 3OT9A 4KAVA 2GSNA 3M8WA 1AUKA 1AJAA 3B5QA 2ANHA 2W5WA 1KH7A 4LQYA 3MK2A 2IFYA 2IUCB 1EI6A 4MY4A 2W5XA 2ZKTA 1SHNA 2XR9A 1Y6VA 1EW9A 2X98A 4UPKA 4TN0A 1K7HA 2W5TA 1ZEBA 3WAWA 5LIAA 4KM4A 3T00A 3NKNA 5K4PA 1ELZA 4GTYA 1ZEFA 2RH6A 1HDHA 5EGHA 4UPLA 4FDJA 3TG0A 2GSUA 1KHJA 2XRGA 3LXQA 1HQAA 1ALJA 4CYRA 5L0KA 1ED8A 4LR7A 4LREA 1FSUA 3DYCA 1KHLA 1N2LA 4CXKA 1ZEDA 5IJSA 3NKOA 1AJCA 1O99A 2W5VA 4NWJA 3IGZB 1ELXA 1KH5A 1B8JA 1N2KA 3SZYA 3WAYA 4MIVA 5LRMA 1ANIA 5EGEA 3BDGB 4N7TA 1Y7AA 3UN2A 1HJKA 4UOPA 4B56A 4ZGAA 2W8DA 4LRFA 3UN5A 5GOVA 5TJ3A 1EJJA 4UORA 1ED9A 3WAXA 5LRNA 1O98A 3A52A 1KHKA 2VQRA 5DLTA 5LQQA 4LR8A 2IUCA 4ZG6A 1EQJA 3T02A 1KHNA 4MHXA 1KH9A 2GSOA 2G9YA 4CXUA 4KJGA 3WAVA 4LRAA 3ED4A 4YR1A 1EW8A 4CXSA 4LRBA 3NVLA 3Q3QA 5C66A 5KXAA 5HRTA 2W8SA 1E2SP 1SHQA 1E1ZP 1ELYA 3UN3A 1AJDA 2QZUA 4CYSA 3IGYB 1E33P 3M8ZA 3M7VA 4LR9A 1P49A 4KJDA 3MK0A 4ZG7A 4ZG9A 4KAYA 3WBHA 3TWZA 3UO0A 3UNYA 3MK1A 4LR2A 4LRCA 5GRRA 1URAA
chains in the Genus database with same CATH topology
1ALKA 4GTXA 3NKQA 5DLWA 3T01A 5L0EA 4LRDA 1URBA 1KH4A 3NKPA 4GTZA 5AJ9A 5INHA 2W5SA 3E2DA 3BDGA 2GLQA 3NKRA 1ANJA 4GTWA 3BDFA 3TX0A 3BDHA 4QAXA 3KD8A 1AJBA 4FDIA 3NKMA 3SZZA 1ALIA 5DLVA 3M8YA 4UPIA 5IJQA 1E3CP 2GA3A 2W5RA 2D1GA 3DPCA 5L0BA 3IDDA 4UPHA 4UOOA 3CMRA 1EW2A 4NWXA 2W5QA 1ALHA 3OT9A 4KAVA 2GSNA 3M8WA 1AUKA 1AJAA 3B5QA 2ANHA 2W5WA 1KH7A 4LQYA 3MK2A 2IFYA 2IUCB 1EI6A 4MY4A 2W5XA 2ZKTA 1SHNA 2XR9A 1Y6VA 1EW9A 2X98A 4UPKA 4TN0A 1K7HA 2W5TA 1ZEBA 3WAWA 5LIAA 4KM4A 3T00A 3NKNA 5K4PA 1ELZA 4GTYA 1ZEFA 2RH6A 1HDHA 5EGHA 4UPLA 4FDJA 3TG0A 2GSUA 1KHJA 2XRGA 3LXQA 1HQAA 1ALJA 4CYRA 5L0KA 1ED8A 4LR7A 4LREA 1FSUA 3DYCA 1KHLA 1N2LA 4CXKA 1ZEDA 5IJSA 3NKOA 1AJCA 1O99A 2W5VA 4NWJA 3IGZB 1ELXA 1KH5A 1B8JA 1N2KA 3SZYA 3WAYA 4MIVA 5LRMA 1ANIA 5EGEA 3BDGB 4N7TA 1Y7AA 3UN2A 1HJKA 4UOPA 4B56A 4ZGAA 2W8DA 4LRFA 3UN5A 5GOVA 5TJ3A 1EJJA 4UORA 1ED9A 3WAXA 5LRNA 1O98A 3A52A 1KHKA 2VQRA 5DLTA 5LQQA 4LR8A 2IUCA 4ZG6A 1EQJA 3T02A 1KHNA 4MHXA 1KH9A 2GSOA 2G9YA 4CXUA 4KJGA 3WAVA 4LRAA 3ED4A 4YR1A 1EW8A 4CXSA 4LRBA 3NVLA 3Q3QA 5C66A 5KXAA 5HRTA 2W8SA 1E2SP 1SHQA 1E1ZP 1ELYA 3UN3A 1AJDA 2QZUA 4CYSA 3IGYB 1E33P 3M8ZA 3M7VA 4LR9A 1P49A 4KJDA 3MK0A 4ZG7A 4ZG9A 4KAYA 3WBHA 3TWZA 3UO0A 3UNYA 3MK1A 4LR2A 4LRCA 5GRRA 1URAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1ALK A;  4GTX A;  3NKQ A;  5DLW A;  3T01 A;  5L0E A;  4LRD A;  1URB A;  1KH4 A;  3NKP A;  4GTZ A;  5AJ9 A;  5INH A;  2W5S A;  3E2D A;  3BDG A;  2GLQ A;  3NKR A;  1ANJ A;  4GTW A;  3BDF A;  3TX0 A;  3BDH A;  4QAX A;  3KD8 A;  1AJB A;  4FDI A;  3NKM A;  3SZZ A;  1ALI A;  5DLV A;  3M8Y A;  4UPI A;  5IJQ A;  1E3C P;  2GA3 A;  2W5R A;  2D1G A;  3DPC A;  5L0B A;  3IDD A;  4UPH A;  4UOO A;  3CMR A;  1EW2 A;  4NWX A;  2W5Q A;  1ALH A;  3OT9 A;  4KAV A;  2GSN A;  3M8W A;  1AUK A;  1AJA A;  3B5Q A;  2ANH A;  2W5W A;  1KH7 A;  4LQY A;  3MK2 A;  2IFY A;  2IUC B;  1EI6 A;  4MY4 A;  2W5X A;  2ZKT A;  1SHN A;  2XR9 A;  1Y6V A;  1EW9 A;  2X98 A;  4UPK A;  4TN0 A;  1K7H A;  2W5T A;  1ZEB A;  3WAW A;  5LIA A;  4KM4 A;  3T00 A;  3NKN A;  5K4P A;  1ELZ A;  4GTY A;  1ZEF A;  2RH6 A;  1HDH A;  5EGH A;  4UPL A;  4FDJ A;  3TG0 A;  2GSU A;  1KHJ A;  2XRG A;  3LXQ A;  1HQA A;  1ALJ A;  4CYR A;  5L0K A;  1ED8 A;  4LR7 A;  4LRE A;  1FSU A;  3DYC A;  1KHL A;  1N2L A;  4CXK A;  1ZED A;  5IJS A;  3NKO A;  1AJC A;  1O99 A;  2W5V A;  4NWJ A;  3IGZ B;  1ELX A;  1KH5 A;  1B8J A;  1N2K A;  3SZY A;  3WAY A;  4MIV A;  5LRM A;  1ANI A;  5EGE A;  3BDG B;  4N7T A;  1Y7A A;  3UN2 A;  1HJK A;  4UOP A;  4B56 A;  4ZGA A;  2W8D A;  4LRF A;  3UN5 A;  5GOV A;  5TJ3 A;  1EJJ A;  4UOR A;  1ED9 A;  3WAX A;  5LRN A;  1O98 A;  3A52 A;  1KHK A;  2VQR A;  5DLT A;  5LQQ A;  4LR8 A;  2IUC A;  4ZG6 A;  1EQJ A;  3T02 A;  1KHN A;  4MHX A;  1KH9 A;  2GSO A;  2G9Y A;  4CXU A;  4KJG A;  3WAV A;  4LRA A;  3ED4 A;  4YR1 A;  1EW8 A;  4CXS A;  4LRB A;  3NVL A;  3Q3Q A;  5C66 A;  5KXA A;  5HRT A;  2W8S A;  1E2S P;  1SHQ A;  1E1Z P;  1ELY A;  3UN3 A;  1AJD A;  2QZU A;  4CYS A;  3IGY B;  1E33 P;  3M8Z A;  3M7V A;  4LR9 A;  1P49 A;  4KJD A;  3MK0 A;  4ZG7 A;  4ZG9 A;  4KAY A;  3WBH A;  3TWZ A;  3UO0 A;  3UNY A;  3MK1 A;  4LR2 A;  4LRC A;  5GRR A;  1URA A; 
#chains in the Genus database with same CATH topology
 1ALK A;  4GTX A;  3NKQ A;  5DLW A;  3T01 A;  5L0E A;  4LRD A;  1URB A;  1KH4 A;  3NKP A;  4GTZ A;  5AJ9 A;  5INH A;  2W5S A;  3E2D A;  3BDG A;  2GLQ A;  3NKR A;  1ANJ A;  4GTW A;  3BDF A;  3TX0 A;  3BDH A;  4QAX A;  3KD8 A;  1AJB A;  4FDI A;  3NKM A;  3SZZ A;  1ALI A;  5DLV A;  3M8Y A;  4UPI A;  5IJQ A;  1E3C P;  2GA3 A;  2W5R A;  2D1G A;  3DPC A;  5L0B A;  3IDD A;  4UPH A;  4UOO A;  3CMR A;  1EW2 A;  4NWX A;  2W5Q A;  1ALH A;  3OT9 A;  4KAV A;  2GSN A;  3M8W A;  1AUK A;  1AJA A;  3B5Q A;  2ANH A;  2W5W A;  1KH7 A;  4LQY A;  3MK2 A;  2IFY A;  2IUC B;  1EI6 A;  4MY4 A;  2W5X A;  2ZKT A;  1SHN A;  2XR9 A;  1Y6V A;  1EW9 A;  2X98 A;  4UPK A;  4TN0 A;  1K7H A;  2W5T A;  1ZEB A;  3WAW A;  5LIA A;  4KM4 A;  3T00 A;  3NKN A;  5K4P A;  1ELZ A;  4GTY A;  1ZEF A;  2RH6 A;  1HDH A;  5EGH A;  4UPL A;  4FDJ A;  3TG0 A;  2GSU A;  1KHJ A;  2XRG A;  3LXQ A;  1HQA A;  1ALJ A;  4CYR A;  5L0K A;  1ED8 A;  4LR7 A;  4LRE A;  1FSU A;  3DYC A;  1KHL A;  1N2L A;  4CXK A;  1ZED A;  5IJS A;  3NKO A;  1AJC A;  1O99 A;  2W5V A;  4NWJ A;  3IGZ B;  1ELX A;  1KH5 A;  1B8J A;  1N2K A;  3SZY A;  3WAY A;  4MIV A;  5LRM A;  1ANI A;  5EGE A;  3BDG B;  4N7T A;  1Y7A A;  3UN2 A;  1HJK A;  4UOP A;  4B56 A;  4ZGA A;  2W8D A;  4LRF A;  3UN5 A;  5GOV A;  5TJ3 A;  1EJJ A;  4UOR A;  1ED9 A;  3WAX A;  5LRN A;  1O98 A;  3A52 A;  1KHK A;  2VQR A;  5DLT A;  5LQQ A;  4LR8 A;  2IUC A;  4ZG6 A;  1EQJ A;  3T02 A;  1KHN A;  4MHX A;  1KH9 A;  2GSO A;  2G9Y A;  4CXU A;  4KJG A;  3WAV A;  4LRA A;  3ED4 A;  4YR1 A;  1EW8 A;  4CXS A;  4LRB A;  3NVL A;  3Q3Q A;  5C66 A;  5KXA A;  5HRT A;  2W8S A;  1E2S P;  1SHQ A;  1E1Z P;  1ELY A;  3UN3 A;  1AJD A;  2QZU A;  4CYS A;  3IGY B;  1E33 P;  3M8Z A;  3M7V A;  4LR9 A;  1P49 A;  4KJD A;  3MK0 A;  4ZG7 A;  4ZG9 A;  4KAY A;  3WBH A;  3TWZ A;  3UO0 A;  3UNY A;  3MK1 A;  4LR2 A;  4LRC A;  5GRR A;  1URA A; 
#chains in the Genus database with same CATH homology
 1ALK A;  4GTX A;  3NKQ A;  5DLW A;  3T01 A;  5L0E A;  4LRD A;  1URB A;  1KH4 A;  3NKP A;  4GTZ A;  5AJ9 A;  5INH A;  2W5S A;  3E2D A;  3BDG A;  2GLQ A;  3NKR A;  1ANJ A;  4GTW A;  3BDF A;  3TX0 A;  3BDH A;  4QAX A;  3KD8 A;  1AJB A;  4FDI A;  3NKM A;  3SZZ A;  1ALI A;  5DLV A;  3M8Y A;  4UPI A;  5IJQ A;  1E3C P;  2GA3 A;  2W5R A;  2D1G A;  3DPC A;  5L0B A;  3IDD A;  4UPH A;  4UOO A;  3CMR A;  1EW2 A;  4NWX A;  2W5Q A;  1ALH A;  3OT9 A;  4KAV A;  2GSN A;  3M8W A;  1AUK A;  1AJA A;  3B5Q A;  2ANH A;  2W5W A;  1KH7 A;  4LQY A;  3MK2 A;  2IFY A;  2IUC B;  1EI6 A;  4MY4 A;  2W5X A;  2ZKT A;  1SHN A;  2XR9 A;  1Y6V A;  1EW9 A;  2X98 A;  4UPK A;  4TN0 A;  1K7H A;  2W5T A;  1ZEB A;  3WAW A;  5LIA A;  4KM4 A;  3T00 A;  3NKN A;  5K4P A;  1ELZ A;  4GTY A;  1ZEF A;  2RH6 A;  1HDH A;  5EGH A;  4UPL A;  4FDJ A;  3TG0 A;  2GSU A;  1KHJ A;  2XRG A;  3LXQ A;  1HQA A;  1ALJ A;  4CYR A;  5L0K A;  1ED8 A;  4LR7 A;  4LRE A;  1FSU A;  3DYC A;  1KHL A;  1N2L A;  4CXK A;  1ZED A;  5IJS A;  3NKO A;  1AJC A;  1O99 A;  2W5V A;  4NWJ A;  3IGZ B;  1ELX A;  1KH5 A;  1B8J A;  1N2K A;  3SZY A;  3WAY A;  4MIV A;  5LRM A;  1ANI A;  5EGE A;  3BDG B;  4N7T A;  1Y7A A;  3UN2 A;  1HJK A;  4UOP A;  4B56 A;  4ZGA A;  2W8D A;  4LRF A;  3UN5 A;  5GOV A;  5TJ3 A;  1EJJ A;  4UOR A;  1ED9 A;  3WAX A;  5LRN A;  1O98 A;  3A52 A;  1KHK A;  2VQR A;  5DLT A;  5LQQ A;  4LR8 A;  2IUC A;  4ZG6 A;  1EQJ A;  3T02 A;  1KHN A;  4MHX A;  1KH9 A;  2GSO A;  2G9Y A;  4CXU A;  4KJG A;  3WAV A;  4LRA A;  3ED4 A;  4YR1 A;  1EW8 A;  4CXS A;  4LRB A;  3NVL A;  3Q3Q A;  5C66 A;  5KXA A;  5HRT A;  2W8S A;  1E2S P;  1SHQ A;  1E1Z P;  1ELY A;  3UN3 A;  1AJD A;  2QZU A;  4CYS A;  3IGY B;  1E33 P;  3M8Z A;  3M7V A;  4LR9 A;  1P49 A;  4KJD A;  3MK0 A;  4ZG7 A;  4ZG9 A;  4KAY A;  3WBH A;  3TWZ A;  3UO0 A;  3UNY A;  3MK1 A;  4LR2 A;  4LRC A;  5GRR A;  1URA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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