4O67A

Human cyclic gmp-amp synthase (cgas) in complex with gamp
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
361
structure length
346
Chain Sequence
GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNKENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cyclic GMP-AMP synthase
publication title The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 116
structure length 346
sequence length 361
chains with identical sequence B
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4o67A01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4o67A02
4O67A 4MKPA 4OAFA 4K9BA 4LEVA 4NXXA 4AT9A 4ATBA 4NXTA 4O69A 4AT8B 4AT7B 4LEWA 4NXVA 4NXWA 4K8VA 4KB6A 4JLXA 4ATBB 4O68A 4OAGA 4OAHA 4AT9B 4WOYA 4LEYA 4K97A 4NXUA 4K9AA 4K98A 4O6AA 4K96A 4K99A 4LEZA 4JLZA 4KM5A 4AT8A 4OAIZ 4AT7A
chains in the Genus database with same CATH superfamily
4WC5A 4QZ8A 1UETA 4MKPA 4NKTA 4P4MA 4WCWA 5TZVA 9ICEA 4LT6A 5J0PA 3JCFA 1BPZA 4I2FA 3AQMA 4XQ8A 5D46A 2BPFA 5CR0A 4UB4A 3C2LA 9ICHA 3HIYA 4QZHA 1PX5A 3JPTA 1ZQQA 3LK9A 4WQKA 4HX0A 2HN2A 1MIWA 2M2VA 4K96A 7ICKA 4UD4A 3ER8C 4AT8A 7ICSA 5D61A 3HJ4A 4QZGA 3OUYA 2BBJA 4XQ7A 4WC6A 1YLQA 1ZQTA 2ZHBA 1RPLA 4YD1A 3RH5A 1HUOA 3RJIA 1JN3A 1ZQBA 2PFQA 4EEDA 7ICIA 2M2TA 1BPBA 3RJGA 1NOMA 4OAGA 4X4PA 1ZQVA 1VFGA 4M04A 3H39A 2DR9A 7ICMA 3UQ0A 2GAFD 3HX0A 5HC9A 1VJ7A 7ICTA 4PH5A 9ICOA 3RJFA 9ICNA 5CFUA 1ZQSA 3UXOA 2DR8A 4EEBA 4UAZA 3TFRA 3JPNA 5J0RA 1ZJMA 5J0UA 9ICGA 2BBHA 3C18A 1R8CA 8ICSA 4S3NA 5J0WA 5HRBA 4PGQA 5D63A 4FHWA 4RPYA 7ICUA 5DEDA 5J2EA 9ICVA 3ISBA 5J2JA 4QZ9A 1BPXA 4K4GA 9ICCA 1ZQPA 3JPQA 5D4BA 1TFWA 4I29A 4NXXA 5CJ7A 4RQ5A 1ZQCA 4ATBA 3K7DA 4RQ3A 1ZQJA 1ZQIA 4O69A 4KLEA 4RWPA 4RT2A 3MCRA 3C5GA 3HWTA 3UXPA 4KLJA 4MFCA 1HUZA 4JLXA 2PXIA 4F5OA 4FHXA 5J0YA 2HN1A 2IHMA 4NKUA 9ICKA 4IQVA 2PBEA 3GDXA 2DVIA 3UQ2A 4I27A 4P2HA 7ICPA 4X4NA 4RQ6A 4FHVA 3AQLA 5J2GA 4RPZA 4MFFA 5CFTA 4I2EA 1MIVA 5DDMA 8ICNA 3WFSC 4NY8A 1ZJNA 4IQWA 5HHIA 5J2FA 4M0AA 1R8AA 3AQNA 2PFPA 1ZQEA 2EWRA 4M47A 4OAHA 4AT9B 4IG8A 4XUSA 2DRAA 1JMSA 5D49A 3AQKA 5CP2A 3C2KA 4UB5A 4UBCA 4RPXA 4YD2A 2ZHAA 3MGIA 2ZH2A 3C2MA 5DBBA 5J2HA 4KM5A 4QZIA 5HRLA 4X4RA 3PMLA 4NLNA 4Z6DA 4WBZA 3PMNA 5EOZA 4LEVA 4I2AA 1KEJA 5IIJA 5DB7A 9ICIA 4AT8B 3JPRA 1ZQWA 8ICGA 4NXVA 3OUYB 2ZH7A 4R66A 2FCLA 2FMPA 5DB9A 4RT3A 2ISOA 8ICFA 3H37A 4K8VA 4WBYA 2PFNA 4K4IA 4QZEA 5DB8A 4IQUA 5DDYA 2DRBA 3V72A 8ICJA 4RQ7A 4K97A 4PHPA 4Z6FA 4F5NA 5BOMA 3PNCA 4PHEA 4YMOA 4OAIZ 3WFOA 4I2CA 3NVOA 3OVBA 3JYYA 5CHEA 4RQ2A 1BPYA 9ICQA 4WC1A 4R63A 1ZQOA 4GXKA 2PFOA 4RQ8A 4LVSA 5J0SA 2GA9D 4X0BA 2M2UA 4WC4A 4PPXA 8ICBA 4UAWA 4RWOA 4Z6CA 3H3AA 4K98A 4I0UA 3JPOA 2BCVA 3B0YA 4WH5A 4O9MA 4K9BA 1V4AA 8ICLA 5HRGA 5J2IA 4FO6A 4PHAA 9ICTA 3WFQE 4QZDA 2B4VA 3PHZA 3V7KA 3B0XA 5DKWA 4MFAA 5CWRA 2ZH6A 1ZQDA 3JZ0A 4NLKA 3NYBA 4P4PA 8ICKA 8ICQA 4ATBB 4UBBA 8ICMA 4UAYA 1ZQXA 5DECA 5CA7A 2ZH3A 1ZQAA 8ICEA 4NXUA 3H38A 9ICFA 4UB3A 4FO1A 1R8BA 4NLZA 9ICUA 4XRHA 8ICRA 4QZFA 1MIYA 4GXIA 1MQ2A 8ICAA 9ICSA 7ICVA 5J0TA 5IIOA 2BPGA 3AU6A 2BPCA 5HREA 4F5PA 3HW8A 2ZH8A 4X5VA 4JWNA 3EF2A 4KLFA 5HHHA 4KLMA 4M2YA 4LZDA 5CHGA 4KLUA 2ZH5A 1XSNA 4K99A 3UXNA 5DB6A 5IINA 5CB1A 4O5CA 2RFFA 4DOBA 4O67A 9ICLA 3RJKA 2BCSA 8ICUA 4RQ1A 1GPJA 2GWSA 8ICTA 4JWMA 1ZQNA 5J29A 3V7JA 7ICLA 4NXWA 2VANA 4M9HA 4KB6A 4LZGA 3OV7A 3RJJA 5DBCA 5DBAA 5HR9A 2BE3A 8ICXA 5B3QA 4X4OA 8ICCA 4I2IA 8ICIA 9ICMA 4FH5A 5J0XA 4M9JA 3CK6A 4E7XA 4FH3A 4DOAA 4R65A 4R64A 3K75D 2IHOA 3JPPA 3MBYA 4KLGA 3JPSA 3OVAA 2ZH1A 3AU2A 8ICHA 4IQTA 4UB1A 3UPQA 1FA0A 7ICEA 4O6AA 4X4TA 5J0QA 2FMSA 3L9DA 1ZQKA 4AT7A 5J2CA 3TFSA 7ICNA 1ZQLA 1ZQRA 1ZQGA 4AT9A 4P4OA 5CFSA 2P66A 2ID1A 2B56A 4X4UA 7ICOA 3ER9B 1R89A 4O68A 8ICWA 4I2HA 3MDCA 4WC0A 1TV9A 2FMQA 1TVAA 1F5AA 4UD5A 5J2DA 4NM2A 3WFRE 2ZH9A 5IIIA 4WQLA 5F2VO 9ICAA 1KDHA 5IIKA 7ICGA 4DO9A 1XSPA 1JQRA 4QZCA 4PGXA 4O5KA 9ICXA 4I28A 9ICWA 5J2BA 1BPEA 4I2BA 2HHPA 5J2AA 2DR7A 5J0OA 4TUPA 3C66A 3MGHA 1ZQHA 1RZTA 1UEVA 2Q66A 1KNYA 3NWIA 1NO5A 4MF8A 4K4HA 4WC3A 4I2JA 4KLLA 4YCXA 4TUQA 3RJEA 4LEZA 5IIMA 3OVSA 9ICJA 2M2WA 1ZQMA 3ISDA 2IUBA 2BCRA 3OGUA 4O5EA 4PHDA 8ICPA 1UEUA 1ZQYA 4E80A 1JAJA 3RH6A 4NXTA 4RQ0A 4DOCA 4WC7A 4TUSA 4GXJA 4LEWA 9ICRA 4EGWA 4X4VA 4RWQA 4YMNA 4X4SA 4QZBA 4F5QA 4RWNA 4RQ4A 4EV6A 5BPCA 4KLQA 2B51A 4LEYA 2ISPA 4M9LA 4K9AA 4XA5A 5JTGA 7ICHA 4EBJA 2DR5A 4E8FA 4X0AA 1ZQUA 3V7LA 3HJ1A 5IILA 4EBKA 5HRKA 1TFYA 1MQ3A 4YN4A 3UPSA 4KLOA 8ICYA 7ICJA 5HRFA 4N7RA 3WFPA 4WC2A 5BOLA 3MDAA 5B3PA 4I2DA 3ERCC 7ICQA 4X4QA 1BPDA 2BCUA 2O5AA 2O1PA 4PGYA 4KLDA 1Q79A 3RJHA 4JLZA 2NRKA 5HRHA 4XJEA 1XSLA 4F5RA 2BCQA 4M9NA 4OAFA 4TURA 8ICZA 3C5FA 3NKUA 3LQCB 8ICOA 1Q78A 3RH4A 4M5DA 4FHYA 4AT7B 4EP7A 2ZH4A 3AUOA 4YMMA 4KLHA 3OWGA 8ICVA 4M9GA 9ICPA 4KLSA 4WOYA 2I9GA 4NXZA 5HRIA 5HRDA 5D62A 1ZQFA 3ISCA 4MF2A 4I2GA 4QZAA 4NM1A 1ZQZA 4KLIA 5J2KA 1OU5A 2W9MA 4FHPA 4Z6EA 1WOTA 4UB2A 7ICFA 9ICBA 7ICRA 4KLTA
chains in the Genus database with same CATH topology
4FHVA 1UETA 4MKPA 2ZH9A 4NKTA 4WQLA 5CFTA 4LT6A 1R8AA 2ZH8A 2HHPA 2EWRA 2DR7A 3EF2A 4OAHA 4AT9B 3C66A 3HIYA 2DRAA 4WQKA 1UEVA 2Q66A 4HX0A 2ZHAA 2ZH5A 4K96A 4UD4A 4K99A 2ZH2A 4LEZA 3ER8C 3OVSA 4KM5A 4AT8A 5D61A 3HJ4A 4X4RA 3OUYA 4O67A 1UEUA 4LEVA 4E80A 2ZHBA 1GPJA 4NXTA 4AT8B 4LEWA 4NXVA 3OUYB 2ZH7A 4X4VA 2FCLA 4NXWA 4X4SA 4K8VA 4KB6A 4OAGA 3OV7A 4X4PA 2DRBA 2B51A 2DR9A 4LEYA 4K97A 4K9AA 2GAFD 2DR5A 4E8FA 4OAIZ 5CFUA 3HJ1A 5B3QA 4X4OA 3OVBA 1TFYA 5CHEA 4FH5A 2DR8A 4E7XA 4FH3A 4N7RA 5B3PA 3ERCC 4X4QA 2IHOA 1R8CA 2GA9D 5D63A 4FHWA 2O1PA 3OVAA 2ZH1A 1FA0A 4K98A 4O6AA 4X4TA 1Q79A 4JLZA 4XJEA 4AT7A 4WH5A 4OAFA 4K9BA 1TFWA 4NXXA 4AT9A 3NKUA 4ATBA 3K7DA 5CFSA 1Q78A 4O69A 2B4VA 4M5DA 4FHYA 4AT7B 3PHZA 2B56A 4EP7A 2ZH4A 4X4UA 3MCRA 2ZH6A 3ER9B 3OWGA 3NYBA 4JLXA 4ATBB 1R89A 4O68A 4WOYA 4FHXA 5D62A 2ZH3A 4NKUA 4NXUA 4FO1A 2DVIA 1R8BA 4FHPA 1F5AA 4UD5A 4X4NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4O67 A;  4MKP A;  4OAF A;  4K9B A;  4LEV A;  4NXX A;  4AT9 A;  4ATB A;  4NXT A;  4O69 A;  4AT8 B;  4AT7 B;  4LEW A;  4NXV A;  4NXW A;  4K8V A;  4KB6 A;  4JLX A;  4ATB B;  4O68 A;  4OAG A;  4OAH A;  4AT9 B;  4WOY A;  4LEY A;  4K97 A;  4NXU A;  4K9A A;  4K98 A;  4O6A A;  4K96 A;  4K99 A;  4LEZ A;  4JLZ A;  4KM5 A;  4AT8 A;  4OAI Z;  4AT7 A; 
#chains in the Genus database with same CATH topology
 4WC5 A;  4QZ8 A;  1UET A;  4MKP A;  4NKT A;  4P4M A;  4WCW A;  5TZV A;  9ICE A;  4LT6 A;  5J0P A;  3JCF A;  1BPZ A;  4I2F A;  3AQM A;  4XQ8 A;  5D46 A;  2BPF A;  5CR0 A;  4UB4 A;  3C2L A;  9ICH A;  3HIY A;  4QZH A;  1PX5 A;  3JPT A;  1ZQQ A;  3LK9 A;  4WQK A;  4HX0 A;  2HN2 A;  1MIW A;  2M2V A;  4K96 A;  7ICK A;  4UD4 A;  3ER8 C;  4AT8 A;  7ICS A;  5D61 A;  3HJ4 A;  4QZG A;  3OUY A;  2BBJ A;  4XQ7 A;  4WC6 A;  1YLQ A;  1ZQT A;  2ZHB A;  1RPL A;  4YD1 A;  3RH5 A;  1HUO A;  3RJI A;  1JN3 A;  1ZQB A;  2PFQ A;  4EED A;  7ICI A;  2M2T A;  1BPB A;  3RJG A;  1NOM A;  4OAG A;  4X4P A;  1ZQV A;  1VFG A;  4M04 A;  3H39 A;  2DR9 A;  7ICM A;  3UQ0 A;  2GAF D;  3HX0 A;  5HC9 A;  1VJ7 A;  7ICT A;  4PH5 A;  9ICO A;  3RJF A;  9ICN A;  5CFU A;  1ZQS A;  3UXO A;  2DR8 A;  4EEB A;  4UAZ A;  3TFR A;  3JPN A;  5J0R A;  1ZJM A;  5J0U A;  9ICG A;  2BBH A;  3C18 A;  1R8C A;  8ICS A;  4S3N A;  5J0W A;  5HRB A;  4PGQ A;  5D63 A;  4FHW A;  4RPY A;  7ICU A;  5DED A;  5J2E A;  9ICV A;  3ISB A;  5J2J A;  4QZ9 A;  1BPX A;  4K4G A;  9ICC A;  1ZQP A;  3JPQ A;  5D4B A;  1TFW A;  4I29 A;  4NXX A;  5CJ7 A;  4RQ5 A;  1ZQC A;  4ATB A;  3K7D A;  4RQ3 A;  1ZQJ A;  1ZQI A;  4O69 A;  4KLE A;  4RWP A;  4RT2 A;  3MCR A;  3C5G A;  3HWT A;  3UXP A;  4KLJ A;  4MFC A;  1HUZ A;  4JLX A;  2PXI A;  4F5O A;  4FHX A;  5J0Y A;  2HN1 A;  2IHM A;  4NKU A;  9ICK A;  4IQV A;  2PBE A;  3GDX A;  2DVI A;  3UQ2 A;  4I27 A;  4P2H A;  7ICP A;  4X4N A;  4RQ6 A;  4FHV A;  3AQL A;  5J2G A;  4RPZ A;  4MFF A;  5CFT A;  4I2E A;  1MIV A;  5DDM A;  8ICN A;  3WFS C;  4NY8 A;  1ZJN A;  4IQW A;  5HHI A;  5J2F A;  4M0A A;  1R8A A;  3AQN A;  2PFP A;  1ZQE A;  2EWR A;  4M47 A;  4OAH A;  4AT9 B;  4IG8 A;  4XUS A;  2DRA A;  1JMS A;  5D49 A;  3AQK A;  5CP2 A;  3C2K A;  4UB5 A;  4UBC A;  4RPX A;  4YD2 A;  2ZHA A;  3MGI A;  2ZH2 A;  3C2M A;  5DBB A;  5J2H A;  4KM5 A;  4QZI A;  5HRL A;  4X4R A;  3PML A;  4NLN A;  4Z6D A;  4WBZ A;  3PMN A;  5EOZ A;  4LEV A;  4I2A A;  1KEJ A;  5IIJ A;  5DB7 A;  9ICI A;  4AT8 B;  3JPR A;  1ZQW A;  8ICG A;  4NXV A;  3OUY B;  2ZH7 A;  4R66 A;  2FCL A;  2FMP A;  5DB9 A;  4RT3 A;  2ISO A;  8ICF A;  3H37 A;  4K8V A;  4WBY A;  2PFN A;  4K4I A;  4QZE A;  5DB8 A;  4IQU A;  5DDY A;  2DRB A;  3V72 A;  8ICJ A;  4RQ7 A;  4K97 A;  4PHP A;  4Z6F A;  4F5N A;  5BOM A;  3PNC A;  4PHE A;  4YMO A;  4OAI Z;  3WFO A;  4I2C A;  3NVO A;  3OVB A;  3JYY A;  5CHE A;  4RQ2 A;  1BPY A;  9ICQ A;  4WC1 A;  4R63 A;  1ZQO A;  4GXK A;  2PFO A;  4RQ8 A;  4LVS A;  5J0S A;  2GA9 D;  4X0B A;  2M2U A;  4WC4 A;  4PPX A;  8ICB A;  4UAW A;  4RWO A;  4Z6C A;  3H3A A;  4K98 A;  4I0U A;  3JPO A;  2BCV A;  3B0Y A;  4WH5 A;  4O9M A;  4K9B A;  1V4A A;  8ICL A;  5HRG A;  5J2I A;  4FO6 A;  4PHA A;  9ICT A;  3WFQ E;  4QZD A;  2B4V A;  3PHZ A;  3V7K A;  3B0X A;  5DKW A;  4MFA A;  5CWR A;  2ZH6 A;  1ZQD A;  3JZ0 A;  4NLK A;  3NYB A;  4P4P A;  8ICK A;  8ICQ A;  4ATB B;  4UBB A;  8ICM A;  4UAY A;  1ZQX A;  5DEC A;  5CA7 A;  2ZH3 A;  1ZQA A;  8ICE A;  4NXU A;  3H38 A;  9ICF A;  4UB3 A;  4FO1 A;  1R8B A;  4NLZ A;  9ICU A;  4XRH A;  8ICR A;  4QZF A;  1MIY A;  4GXI A;  1MQ2 A;  8ICA A;  9ICS A;  7ICV A;  5J0T A;  5IIO A;  2BPG A;  3AU6 A;  2BPC A;  5HRE A;  4F5P A;  3HW8 A;  2ZH8 A;  4X5V A;  4JWN A;  3EF2 A;  4KLF A;  5HHH A;  4KLM A;  4M2Y A;  4LZD A;  5CHG A;  4KLU A;  2ZH5 A;  1XSN A;  4K99 A;  3UXN A;  5DB6 A;  5IIN A;  5CB1 A;  4O5C A;  2RFF A;  4DOB A;  4O67 A;  9ICL A;  3RJK A;  2BCS A;  8ICU A;  4RQ1 A;  1GPJ A;  2GWS A;  8ICT A;  4JWM A;  1ZQN A;  5J29 A;  3V7J A;  7ICL A;  4NXW A;  2VAN A;  4M9H A;  4KB6 A;  4LZG A;  3OV7 A;  3RJJ A;  5DBC A;  5DBA A;  5HR9 A;  2BE3 A;  8ICX A;  5B3Q A;  4X4O A;  8ICC A;  4I2I A;  8ICI A;  9ICM A;  4FH5 A;  5J0X A;  4M9J A;  3CK6 A;  4E7X A;  4FH3 A;  4DOA A;  4R65 A;  4R64 A;  3K75 D;  2IHO A;  3JPP A;  3MBY A;  4KLG A;  3JPS A;  3OVA A;  2ZH1 A;  3AU2 A;  8ICH A;  4IQT A;  4UB1 A;  3UPQ A;  1FA0 A;  7ICE A;  4O6A A;  4X4T A;  5J0Q A;  2FMS A;  3L9D A;  1ZQK A;  4AT7 A;  5J2C A;  3TFS A;  7ICN A;  1ZQL A;  1ZQR A;  1ZQG A;  4AT9 A;  4P4O A;  5CFS A;  2P66 A;  2ID1 A;  2B56 A;  4X4U A;  7ICO A;  3ER9 B;  1R89 A;  4O68 A;  8ICW A;  4I2H A;  3MDC A;  4WC0 A;  1TV9 A;  2FMQ A;  1TVA A;  1F5A A;  4UD5 A;  5J2D A;  4NM2 A;  3WFR E;  2ZH9 A;  5III A;  4WQL A;  5F2V O;  9ICA A;  1KDH A;  5IIK A;  7ICG A;  4DO9 A;  1XSP A;  1JQR A;  4QZC A;  4PGX A;  4O5K A;  9ICX A;  4I28 A;  9ICW A;  5J2B A;  1BPE A;  4I2B A;  2HHP A;  5J2A A;  2DR7 A;  5J0O A;  4TUP A;  3C66 A;  3MGH A;  1ZQH A;  1RZT A;  1UEV A;  2Q66 A;  1KNY A;  3NWI A;  1NO5 A;  4MF8 A;  4K4H A;  4WC3 A;  4I2J A;  4KLL A;  4YCX A;  4TUQ A;  3RJE A;  4LEZ A;  5IIM A;  3OVS A;  9ICJ A;  2M2W A;  1ZQM A;  3ISD A;  2IUB A;  2BCR A;  3OGU A;  4O5E A;  4PHD A;  8ICP A;  1UEU A;  1ZQY A;  4E80 A;  1JAJ A;  3RH6 A;  4NXT A;  4RQ0 A;  4DOC A;  4WC7 A;  4TUS A;  4GXJ A;  4LEW A;  9ICR A;  4EGW A;  4X4V A;  4RWQ A;  4YMN A;  4X4S A;  4QZB A;  4F5Q A;  4RWN A;  4RQ4 A;  4EV6 A;  5BPC A;  4KLQ A;  2B51 A;  4LEY A;  2ISP A;  4M9L A;  4K9A A;  4XA5 A;  5JTG A;  7ICH A;  4EBJ A;  2DR5 A;  4E8F A;  4X0A A;  1ZQU A;  3V7L A;  3HJ1 A;  5IIL A;  4EBK A;  5HRK A;  1TFY A;  1MQ3 A;  4YN4 A;  3UPS A;  4KLO A;  8ICY A;  7ICJ A;  5HRF A;  4N7R A;  3WFP A;  4WC2 A;  5BOL A;  3MDA A;  5B3P A;  4I2D A;  3ERC C;  7ICQ A;  4X4Q A;  1BPD A;  2BCU A;  2O5A A;  2O1P A;  4PGY A;  4KLD A;  1Q79 A;  3RJH A;  4JLZ A;  2NRK A;  5HRH A;  4XJE A;  1XSL A;  4F5R A;  2BCQ A;  4M9N A;  4OAF A;  4TUR A;  8ICZ A;  3C5F A;  3NKU A;  3LQC B;  8ICO A;  1Q78 A;  3RH4 A;  4M5D A;  4FHY A;  4AT7 B;  4EP7 A;  2ZH4 A;  3AUO A;  4YMM A;  4KLH A;  3OWG A;  8ICV A;  4M9G A;  9ICP A;  4KLS A;  4WOY A;  2I9G A;  4NXZ A;  5HRI A;  5HRD A;  5D62 A;  1ZQF A;  3ISC A;  4MF2 A;  4I2G A;  4QZA A;  4NM1 A;  1ZQZ A;  4KLI A;  5J2K A;  1OU5 A;  2W9M A;  4FHP A;  4Z6E A;  1WOT A;  4UB2 A;  7ICF A;  9ICB A;  7ICR A;  4KLT A; 
#chains in the Genus database with same CATH homology
 4FHV A;  1UET A;  4MKP A;  2ZH9 A;  4NKT A;  4WQL A;  5CFT A;  4LT6 A;  1R8A A;  2ZH8 A;  2HHP A;  2EWR A;  2DR7 A;  3EF2 A;  4OAH A;  4AT9 B;  3C66 A;  3HIY A;  2DRA A;  4WQK A;  1UEV A;  2Q66 A;  4HX0 A;  2ZHA A;  2ZH5 A;  4K96 A;  4UD4 A;  4K99 A;  2ZH2 A;  4LEZ A;  3ER8 C;  3OVS A;  4KM5 A;  4AT8 A;  5D61 A;  3HJ4 A;  4X4R A;  3OUY A;  4O67 A;  1UEU A;  4LEV A;  4E80 A;  2ZHB A;  1GPJ A;  4NXT A;  4AT8 B;  4LEW A;  4NXV A;  3OUY B;  2ZH7 A;  4X4V A;  2FCL A;  4NXW A;  4X4S A;  4K8V A;  4KB6 A;  4OAG A;  3OV7 A;  4X4P A;  2DRB A;  2B51 A;  2DR9 A;  4LEY A;  4K97 A;  4K9A A;  2GAF D;  2DR5 A;  4E8F A;  4OAI Z;  5CFU A;  3HJ1 A;  5B3Q A;  4X4O A;  3OVB A;  1TFY A;  5CHE A;  4FH5 A;  2DR8 A;  4E7X A;  4FH3 A;  4N7R A;  5B3P A;  3ERC C;  4X4Q A;  2IHO A;  1R8C A;  2GA9 D;  5D63 A;  4FHW A;  2O1P A;  3OVA A;  2ZH1 A;  1FA0 A;  4K98 A;  4O6A A;  4X4T A;  1Q79 A;  4JLZ A;  4XJE A;  4AT7 A;  4WH5 A;  4OAF A;  4K9B A;  1TFW A;  4NXX A;  4AT9 A;  3NKU A;  4ATB A;  3K7D A;  5CFS A;  1Q78 A;  4O69 A;  2B4V A;  4M5D A;  4FHY A;  4AT7 B;  3PHZ A;  2B56 A;  4EP7 A;  2ZH4 A;  4X4U A;  3MCR A;  2ZH6 A;  3ER9 B;  3OWG A;  3NYB A;  4JLX A;  4ATB B;  1R89 A;  4O68 A;  4WOY A;  4FHX A;  5D62 A;  2ZH3 A;  4NKU A;  4NXU A;  4FO1 A;  2DVI A;  1R8B A;  4FHP A;  1F5A A;  4UD5 A;  4X4N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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