4O67A

Human cyclic gmp-amp synthase (cgas) in complex with gamp
Total Genus 116
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
116
sequence length
361
structure length
346
Chain Sequence
b'GASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNKENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cyclic GMP-AMP synthase
publication title The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 116
structure length 346
sequence length 361
chains with identical sequence B
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4o67A01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4o67A02
4ATBB 4AT7A 4MKPA 4O68A 4OAIZ 4K8VA 4AT9B 4NXWA 4JLXA 4O67A 4KM5A 4NXUA 4AT8A 4NXXA 4K96A 4JLZA 4LEWA 4K9BA 4K9AA 4K99A 4ATBA 4WOYA 4LEZA 4NXTA 4OAFA 4LEVA 4AT9A 4AT7B 4OAHA 4O69A 4NXVA 4K97A 4O6AA 4KB6A 4OAGA 4K98A 4LEYA 4AT8B
chains in the Genus database with same CATH superfamily
4I2JA 5HHHA 2M2WA 4M2YA 4K4GA 5J2GA 5B3QA 7ICSA 4F5QA 7ICQA 4UB5A 4M9NA 8ICWA 4FO1A 2DR7A 4JLZA 1ZQYA 1ZQFA 9ICCA 4NLZA 7ICLA 1ZQDA 4I2EA 1UETA 4HX0A 4M04A 1VFGA 2P66A 4E8FA 4I2DA 4Z6CA 4K97A 4EV6A 4I2GA 5HRHA 4F5OA 2ZH4A 4AT8B 4RPXA 3ER8C 4MFCA 4KLUA 1KNYA 4YMOA 5IIIA 4P4OA 9ICMA 1ZQBA 4NXWA 2ZHAA 4LZDA 4M5DA 8ICSA 3JPOA 5IILA 1Q78A 9ICEA 3NKUA 2HHPA 9ICPA 4PHDA 3TFRA 3TFSA 3ERCC 4WC4A 2DR9A 9ICJA 5J2DA 3RJGA 2GAFD 4QZBA 3JPPA 4Z6EA 2FMSA 9ICOA 4EEDA 5J29A 5F2VO 4KM5A 4WC5A 3V7JA 4KLFA 4KLTA 5J0RA 3AQMA 4XJEA 4RPYA 4JWMA 3JZ0A 8ICRA 4QZEA 4FH3A 1BPBA 5DEDA 2I9GA 1ZQNA 3GDXA 1RZTA 4RQ6A 4AT7A 5J2BA 8ICCA 4RQ0A 4WC0A 4K8VA 4KLGA 4RPZA 2BCUA 4UD4A 4X4TA 4RT2A 7ICEA 4NXUA 3AUOA 4QZHA 4XUSA 4QZGA 2VANA 1BPZA 1TV9A 3RJHA 4K9AA 2BBHA 7ICIA 5HRLA 4OAFA 5D49A 2DVIA 3PNCA 3ISBA 2BPFA 4F5NA 8ICBA 5HRIA 7ICNA 3HX0A 2BE3A 3LQCB 2ZHBA 2PFOA 5J2HA 3B0XA 1YLQA 4KLDA 3MGHA 9ICBA 4MKPA 7ICFA 4LT6A 3OUYB 3JPQA 9ICGA 3MBYA 4KLQA 4M0AA 8ICGA 2IHOA 1ZQQA 7ICJA 8ICLA 4ATBA 4EBKA 4IQWA 3NWIA 3ISDA 5IIKA 3WFQE 4AT9A 4WQKA 8ICVA 4WC3A 8ICZA 4KB6A 4OAGA 1JMSA 1JN3A 5DBBA 4X4QA 3V7KA 1HUZA 1ZQKA 2PBEA 4M9JA 9ICQA 4UD5A 1UEUA 1WOTA 1ZQGA 1ZQRA 7ICMA 3NVOA 4XRHA 4RT3A 4IQVA 1MIWA 4UB1A 7ICRA 2BBJA 2GA9D 1RPLA 4NXXA 1MIVA 3UXNA 3V72A 9ICHA 4FHPA 4YD2A 2FCLA 8ICXA 4TUPA 4O5CA 5DDYA 4I2HA 4QZIA 3H38A 5J0YA 8ICHA 4DOBA 1NOMA 4QZDA 2B4VA 3AQKA 3OV7A 9ICLA 3OVBA 4EEBA 1JQRA 2BPGA 4E80A 1TVAA 1ZQXA 4NM1A 3RJIA 2NRKA 1KEJA 2W9MA 1TFWA 1V4AA 4WC1A 5D46A 3C18A 5JTGA 4AT8A 5D62A 5J0QA 4X4VA 1MIYA 3AU2A 1ZQTA 4PHPA 2PFNA 1ZJNA 4X5VA 4NY8A 4O9MA 4X4UA 3MGIA 5IIJA 4OAHA 4O69A 4FHVA 3MDAA 3OVAA 4X0BA 4K98A 1PX5A 2ZH2A 4KLJA 3HW8A 7ICOA 4RQ5A 5CJ7A 5DB8A 3NYBA 5D4BA 4GXIA 3RH6A 5CA7A 3RJJA 3JCFA 1HUOA 8ICIA 9ICUA 2ZH9A 4X4SA 1FA0A 4RWNA 3AQNA 2DR5A 4LEWA 5D63A 4WBZA 4RQ7A 2B51A 4GXJA 5HHIA 4I29A 4NKUA 5CFUA 3C5GA 1ZQOA 3RJKA 4IG8A 2O5AA 2DRAA 3JPRA 1UEVA 4EP7A 1TFYA 9ICFA 7ICPA 5CHEA 4YD1A 2ZH5A 3C5FA 3C66A 1ZQMA 4RQ2A 4IQUA 4PGXA 4FHYA 1ZQCA 5IIOA 2PFQA 4K4IA 9ICNA 4UB3A 1BPYA 4Z6DA 4F5RA 4FHWA 1JAJA 4RWQA 3K75D 4FO6A 4I28A 4NXZA 4TUSA 4M9GA 9ICRA 8ICMA 4PGYA 4LEYA 4I0UA 4RWPA 4UB2A 4UB4A 4O68A 2BCSA 9ICVA 8ICUA 3L9DA 1ZQJA 4JLXA 3UXPA 3UQ2A 3LK9A 3OUYA 8ICTA 3JPTA 5DDMA 1R89A 4QZ8A 8ICFA 4TUQA 1MQ2A 1ZQVA 9ICKA 2M2UA 4YMNA 8ICPA 1ZQLA 5J2EA 5B3PA 4ATBB 4YN4A 3C2MA 4X4PA 4LVSA 4AT9B 3OGUA 1KDHA 4DOAA 3UPSA 5HRGA 9ICTA 2BPCA 3CK6A 2GWSA 4KLLA 5DBCA 4XQ7A 4QZ9A 3C2LA 2DRBA 4P4PA 2FMQA 3UQ0A 2Q66A 2M2VA 1BPEA 5CB1A 2ISOA 7ICGA 4I2AA 4MFFA 4KLHA 4NXVA 2ZH1A 4QZCA 3EF2A 4E7XA 3HJ1A 3ISCA 3WFSC 5CFSA 2M2TA 4O5EA 4OAIZ 5BPCA 1R8BA 7ICTA 4WC6A 5J0UA 3RJFA 4I2BA 2BCVA 2BCQA 2FMPA 1Q79A 4K96A 9ICIA 4K99A 4WBYA 5CWRA 4JWNA 4WOYA 4NXTA 5J0XA 1OU5A 4LEVA 2BCRA 4M47A 4IQTA 5TZVA 4GXKA 1F5AA 5HR9A 4RQ1A 3UXOA 3MDCA 4DOCA 2ZH6A 4I27A 4X4NA 4WQLA 3WFOA 5DB9A 4WCWA 5HRDA 4XQ8A 3PMLA 3RH4A 5EOZA 4PGQA 5CHGA 5J0SA 4PPXA 1MQ3A 4RWOA 5HRKA 4N7RA 8ICQA 5BOLA 4P2HA 3PHZA 9ICSA 5IINA 4UBBA 4X0AA 3OWGA 3RJEA 2RFFA 4K4HA 5CR0A 5DB6A 2IHMA 2O1PA 4O6AA 3JPSA 1BPDA 3C2KA 3AQLA 1ZQZA 1ZQPA 4I2CA 1ZQUA 5DBAA 5J0WA 2EWRA 4PHAA 4FHXA 4QZFA 1R8AA 3RH5A 3WFPA 3K7DA 4FH5A 5D61A 1ZQHA 4R66A 3OVSA 8ICKA 2ID1A 5J2JA 2ZH7A 2DR8A 3H39A 1ZQWA 4I2FA 7ICHA 1ZQSA 5DB7A 3ER9B 1ZQAA 3PMNA 4R65A 4MF2A 4AT7B 8ICOA 7ICVA 4EGWA 4QZAA 2IUBA 5DECA 8ICYA 5CFTA 5HRBA 4UAWA 4EBJA 3HWTA 9ICAA 1XSPA 3H3AA 4XA5A 4YCXA 5CP2A 4KLOA 4LZGA 5J2CA 4UBCA 4KLSA 4F5PA 5J2KA 4WC2A 4WC7A 5J2IA 1GPJA 2HN2A 4Z6FA 5J0TA 1BPXA 4UAYA 4NKTA 1VJ7A 2B56A 3HJ4A 4LEZA 4I2IA 8ICEA 4WH5A 4NLKA 5BOMA 4KLMA 4P4MA 3H37A 5HC9A 1ZQEA 5J2AA 7ICKA 4R63A 4R64A 4KLEA 5HREA 2ZH3A 4M9LA 8ICAA 2ISPA 4S3NA 2ZH8A 3JYYA 3HIYA 3JPNA 9ICXA 5J0OA 4MFAA 3AU6A 4O5KA 5IIMA 4KLIA 4PHEA 4TURA 4DO9A 3B0YA 4RQ4A 8ICJA 8ICNA 4O67A 2PXIA 1R8CA 3V7LA 2PFPA 4K9BA 5DKWA 2HN1A 1NO5A 4UAZA 5HRFA 4X4RA 3WFRE 4RQ8A 4M9HA 5J2FA 4MF8A 7ICUA 1ZJMA 4NLNA 1XSLA 4X4OA 4RQ3A 5J0PA 9ICWA 1ZQIA 4NM2A 4PH5A 4YMMA 1XSNA 3MCRA 3UPQA
chains in the Genus database with same CATH topology
5CHEA 4MKPA 2ZH5A 4LT6A 3OUYB 3C66A 5B3QA 2IHOA 4FO1A 4N7RA 2DR7A 4FHYA 4JLZA 3PHZA 4ATBA 1UETA 3OWGA 4AT9A 4HX0A 4FHWA 4WQKA 4E8FA 4K97A 2O1PA 4O6AA 4KB6A 4OAGA 4LEYA 2ZH4A 4AT8B 4X4QA 3ER8C 4O68A 2EWRA 4UD5A 1UEUA 4FHXA 1R8AA 4NXWA 3K7DA 4FH5A 4JLXA 5D61A 2ZHAA 3OVSA 2GA9D 4NXXA 2ZH7A 2DR8A 4M5DA 3ER9B 1Q78A 3OUYA 4FHPA 2FCLA 3NKUA 2HHPA 4AT7B 1R89A 5CFTA 2B4VA 3OV7A 3ERCC 3OVBA 2DR9A 4E80A 5B3PA 4ATBB 4X4PA 2GAFD 4AT9B 1TFWA 4KM5A 4AT8A 5D62A 1GPJA 4X4VA 4NKTA 2DRBA 2B56A 3HJ4A 4LEZA 4WH5A 2Q66A 4XJEA 4X4UA 4OAHA 4O69A 4FHVA 3OVAA 4NXVA 2ZH1A 4FH3A 4K98A 2ZH3A 3EF2A 4E7XA 2ZH2A 2ZH8A 3HJ1A 3HIYA 4AT7A 3NYBA 5CFSA 4OAIZ 4K8VA 1R8BA 4UD4A 4X4TA 4O67A 1R8CA 4NXUA 2ZH9A 4X4SA 1FA0A 1Q79A 4K96A 2DR5A 4LEWA 5D63A 4K9BA 4K9AA 4K99A 2B51A 4WOYA 4X4RA 4NXTA 4OAFA 4NKUA 4LEVA 2DVIA 5CFUA 1F5AA 2DRAA 4X4OA 1UEVA 2ZH6A 2ZHBA 4X4NA 3MCRA 4EP7A 4WQLA 1TFYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ATB B;  4AT7 A;  4MKP A;  4O68 A;  4OAI Z;  4K8V A;  4AT9 B;  4NXW A;  4JLX A;  4O67 A;  4KM5 A;  4NXU A;  4AT8 A;  4NXX A;  4K96 A;  4JLZ A;  4LEW A;  4K9B A;  4K9A A;  4K99 A;  4ATB A;  4WOY A;  4LEZ A;  4NXT A;  4OAF A;  4LEV A;  4AT9 A;  4AT7 B;  4OAH A;  4O69 A;  4NXV A;  4K97 A;  4O6A A;  4KB6 A;  4OAG A;  4K98 A;  4LEY A;  4AT8 B; 
#chains in the Genus database with same CATH topology
 4I2J A;  5HHH A;  2M2W A;  4M2Y A;  4K4G A;  5J2G A;  5B3Q A;  7ICS A;  4F5Q A;  7ICQ A;  4UB5 A;  4M9N A;  8ICW A;  4FO1 A;  2DR7 A;  4JLZ A;  1ZQY A;  1ZQF A;  9ICC A;  4NLZ A;  7ICL A;  1ZQD A;  4I2E A;  1UET A;  4HX0 A;  4M04 A;  1VFG A;  2P66 A;  4E8F A;  4I2D A;  4Z6C A;  4K97 A;  4EV6 A;  4I2G A;  5HRH A;  4F5O A;  2ZH4 A;  4AT8 B;  4RPX A;  3ER8 C;  4MFC A;  4KLU A;  1KNY A;  4YMO A;  5III A;  4P4O A;  9ICM A;  1ZQB A;  4NXW A;  2ZHA A;  4LZD A;  4M5D A;  8ICS A;  3JPO A;  5IIL A;  1Q78 A;  9ICE A;  3NKU A;  2HHP A;  9ICP A;  4PHD A;  3TFR A;  3TFS A;  3ERC C;  4WC4 A;  2DR9 A;  9ICJ A;  5J2D A;  3RJG A;  2GAF D;  4QZB A;  3JPP A;  4Z6E A;  2FMS A;  9ICO A;  4EED A;  5J29 A;  5F2V O;  4KM5 A;  4WC5 A;  3V7J A;  4KLF A;  4KLT A;  5J0R A;  3AQM A;  4XJE A;  4RPY A;  4JWM A;  3JZ0 A;  8ICR A;  4QZE A;  4FH3 A;  1BPB A;  5DED A;  2I9G A;  1ZQN A;  3GDX A;  1RZT A;  4RQ6 A;  4AT7 A;  5J2B A;  8ICC A;  4RQ0 A;  4WC0 A;  4K8V A;  4KLG A;  4RPZ A;  2BCU A;  4UD4 A;  4X4T A;  4RT2 A;  7ICE A;  4NXU A;  3AUO A;  4QZH A;  4XUS A;  4QZG A;  2VAN A;  1BPZ A;  1TV9 A;  3RJH A;  4K9A A;  2BBH A;  7ICI A;  5HRL A;  4OAF A;  5D49 A;  2DVI A;  3PNC A;  3ISB A;  2BPF A;  4F5N A;  8ICB A;  5HRI A;  7ICN A;  3HX0 A;  2BE3 A;  3LQC B;  2ZHB A;  2PFO A;  5J2H A;  3B0X A;  1YLQ A;  4KLD A;  3MGH A;  9ICB A;  4MKP A;  7ICF A;  4LT6 A;  3OUY B;  3JPQ A;  9ICG A;  3MBY A;  4KLQ A;  4M0A A;  8ICG A;  2IHO A;  1ZQQ A;  7ICJ A;  8ICL A;  4ATB A;  4EBK A;  4IQW A;  3NWI A;  3ISD A;  5IIK A;  3WFQ E;  4AT9 A;  4WQK A;  8ICV A;  4WC3 A;  8ICZ A;  4KB6 A;  4OAG A;  1JMS A;  1JN3 A;  5DBB A;  4X4Q A;  3V7K A;  1HUZ A;  1ZQK A;  2PBE A;  4M9J A;  9ICQ A;  4UD5 A;  1UEU A;  1WOT A;  1ZQG A;  1ZQR A;  7ICM A;  3NVO A;  4XRH A;  4RT3 A;  4IQV A;  1MIW A;  4UB1 A;  7ICR A;  2BBJ A;  2GA9 D;  1RPL A;  4NXX A;  1MIV A;  3UXN A;  3V72 A;  9ICH A;  4FHP A;  4YD2 A;  2FCL A;  8ICX A;  4TUP A;  4O5C A;  5DDY A;  4I2H A;  4QZI A;  3H38 A;  5J0Y A;  8ICH A;  4DOB A;  1NOM A;  4QZD A;  2B4V A;  3AQK A;  3OV7 A;  9ICL A;  3OVB A;  4EEB A;  1JQR A;  2BPG A;  4E80 A;  1TVA A;  1ZQX A;  4NM1 A;  3RJI A;  2NRK A;  1KEJ A;  2W9M A;  1TFW A;  1V4A A;  4WC1 A;  5D46 A;  3C18 A;  5JTG A;  4AT8 A;  5D62 A;  5J0Q A;  4X4V A;  1MIY A;  3AU2 A;  1ZQT A;  4PHP A;  2PFN A;  1ZJN A;  4X5V A;  4NY8 A;  4O9M A;  4X4U A;  3MGI A;  5IIJ A;  4OAH A;  4O69 A;  4FHV A;  3MDA A;  3OVA A;  4X0B A;  4K98 A;  1PX5 A;  2ZH2 A;  4KLJ A;  3HW8 A;  7ICO A;  4RQ5 A;  5CJ7 A;  5DB8 A;  3NYB A;  5D4B A;  4GXI A;  3RH6 A;  5CA7 A;  3RJJ A;  3JCF A;  1HUO A;  8ICI A;  9ICU A;  2ZH9 A;  4X4S A;  1FA0 A;  4RWN A;  3AQN A;  2DR5 A;  4LEW A;  5D63 A;  4WBZ A;  4RQ7 A;  2B51 A;  4GXJ A;  5HHI A;  4I29 A;  4NKU A;  5CFU A;  3C5G A;  1ZQO A;  3RJK A;  4IG8 A;  2O5A A;  2DRA A;  3JPR A;  1UEV A;  4EP7 A;  1TFY A;  9ICF A;  7ICP A;  5CHE A;  4YD1 A;  2ZH5 A;  3C5F A;  3C66 A;  1ZQM A;  4RQ2 A;  4IQU A;  4PGX A;  4FHY A;  1ZQC A;  5IIO A;  2PFQ A;  4K4I A;  9ICN A;  4UB3 A;  1BPY A;  4Z6D A;  4F5R A;  4FHW A;  1JAJ A;  4RWQ A;  3K75 D;  4FO6 A;  4I28 A;  4NXZ A;  4TUS A;  4M9G A;  9ICR A;  8ICM A;  4PGY A;  4LEY A;  4I0U A;  4RWP A;  4UB2 A;  4UB4 A;  4O68 A;  2BCS A;  9ICV A;  8ICU A;  3L9D A;  1ZQJ A;  4JLX A;  3UXP A;  3UQ2 A;  3LK9 A;  3OUY A;  8ICT A;  3JPT A;  5DDM A;  1R89 A;  4QZ8 A;  8ICF A;  4TUQ A;  1MQ2 A;  1ZQV A;  9ICK A;  2M2U A;  4YMN A;  8ICP A;  1ZQL A;  5J2E A;  5B3P A;  4ATB B;  4YN4 A;  3C2M A;  4X4P A;  4LVS A;  4AT9 B;  3OGU A;  1KDH A;  4DOA A;  3UPS A;  5HRG A;  9ICT A;  2BPC A;  3CK6 A;  2GWS A;  4KLL A;  5DBC A;  4XQ7 A;  4QZ9 A;  3C2L A;  2DRB A;  4P4P A;  2FMQ A;  3UQ0 A;  2Q66 A;  2M2V A;  1BPE A;  5CB1 A;  2ISO A;  7ICG A;  4I2A A;  4MFF A;  4KLH A;  4NXV A;  2ZH1 A;  4QZC A;  3EF2 A;  4E7X A;  3HJ1 A;  3ISC A;  3WFS C;  5CFS A;  2M2T A;  4O5E A;  4OAI Z;  5BPC A;  1R8B A;  7ICT A;  4WC6 A;  5J0U A;  3RJF A;  4I2B A;  2BCV A;  2BCQ A;  2FMP A;  1Q79 A;  4K96 A;  9ICI A;  4K99 A;  4WBY A;  5CWR A;  4JWN A;  4WOY A;  4NXT A;  5J0X A;  1OU5 A;  4LEV A;  2BCR A;  4M47 A;  4IQT A;  5TZV A;  4GXK A;  1F5A A;  5HR9 A;  4RQ1 A;  3UXO A;  3MDC A;  4DOC A;  2ZH6 A;  4I27 A;  4X4N A;  4WQL A;  3WFO A;  5DB9 A;  4WCW A;  5HRD A;  4XQ8 A;  3PML A;  3RH4 A;  5EOZ A;  4PGQ A;  5CHG A;  5J0S A;  4PPX A;  1MQ3 A;  4RWO A;  5HRK A;  4N7R A;  8ICQ A;  5BOL A;  4P2H A;  3PHZ A;  9ICS A;  5IIN A;  4UBB A;  4X0A A;  3OWG A;  3RJE A;  2RFF A;  4K4H A;  5CR0 A;  5DB6 A;  2IHM A;  2O1P A;  4O6A A;  3JPS A;  1BPD A;  3C2K A;  3AQL A;  1ZQZ A;  1ZQP A;  4I2C A;  1ZQU A;  5DBA A;  5J0W A;  2EWR A;  4PHA A;  4FHX A;  4QZF A;  1R8A A;  3RH5 A;  3WFP A;  3K7D A;  4FH5 A;  5D61 A;  1ZQH A;  4R66 A;  3OVS A;  8ICK A;  2ID1 A;  5J2J A;  2ZH7 A;  2DR8 A;  3H39 A;  1ZQW A;  4I2F A;  7ICH A;  1ZQS A;  5DB7 A;  3ER9 B;  1ZQA A;  3PMN A;  4R65 A;  4MF2 A;  4AT7 B;  8ICO A;  7ICV A;  4EGW A;  4QZA A;  2IUB A;  5DEC A;  8ICY A;  5CFT A;  5HRB A;  4UAW A;  4EBJ A;  3HWT A;  9ICA A;  1XSP A;  3H3A A;  4XA5 A;  4YCX A;  5CP2 A;  4KLO A;  4LZG A;  5J2C A;  4UBC A;  4KLS A;  4F5P A;  5J2K A;  4WC2 A;  4WC7 A;  5J2I A;  1GPJ A;  2HN2 A;  4Z6F A;  5J0T A;  1BPX A;  4UAY A;  4NKT A;  1VJ7 A;  2B56 A;  3HJ4 A;  4LEZ A;  4I2I A;  8ICE A;  4WH5 A;  4NLK A;  5BOM A;  4KLM A;  4P4M A;  3H37 A;  5HC9 A;  1ZQE A;  5J2A A;  7ICK A;  4R63 A;  4R64 A;  4KLE A;  5HRE A;  2ZH3 A;  4M9L A;  8ICA A;  2ISP A;  4S3N A;  2ZH8 A;  3JYY A;  3HIY A;  3JPN A;  9ICX A;  5J0O A;  4MFA A;  3AU6 A;  4O5K A;  5IIM A;  4KLI A;  4PHE A;  4TUR A;  4DO9 A;  3B0Y A;  4RQ4 A;  8ICJ A;  8ICN A;  4O67 A;  2PXI A;  1R8C A;  3V7L A;  2PFP A;  4K9B A;  5DKW A;  2HN1 A;  1NO5 A;  4UAZ A;  5HRF A;  4X4R A;  3WFR E;  4RQ8 A;  4M9H A;  5J2F A;  4MF8 A;  7ICU A;  1ZJM A;  4NLN A;  1XSL A;  4X4O A;  4RQ3 A;  5J0P A;  9ICW A;  1ZQI A;  4NM2 A;  4PH5 A;  4YMM A;  1XSN A;  3MCR A;  3UPQ A; 
#chains in the Genus database with same CATH homology
 5CHE A;  4MKP A;  2ZH5 A;  4LT6 A;  3OUY B;  3C66 A;  5B3Q A;  2IHO A;  4FO1 A;  4N7R A;  2DR7 A;  4FHY A;  4JLZ A;  3PHZ A;  4ATB A;  1UET A;  3OWG A;  4AT9 A;  4HX0 A;  4FHW A;  4WQK A;  4E8F A;  4K97 A;  2O1P A;  4O6A A;  4KB6 A;  4OAG A;  4LEY A;  2ZH4 A;  4AT8 B;  4X4Q A;  3ER8 C;  4O68 A;  2EWR A;  4UD5 A;  1UEU A;  4FHX A;  1R8A A;  4NXW A;  3K7D A;  4FH5 A;  4JLX A;  5D61 A;  2ZHA A;  3OVS A;  2GA9 D;  4NXX A;  2ZH7 A;  2DR8 A;  4M5D A;  3ER9 B;  1Q78 A;  3OUY A;  4FHP A;  2FCL A;  3NKU A;  2HHP A;  4AT7 B;  1R89 A;  5CFT A;  2B4V A;  3OV7 A;  3ERC C;  3OVB A;  2DR9 A;  4E80 A;  5B3P A;  4ATB B;  4X4P A;  2GAF D;  4AT9 B;  1TFW A;  4KM5 A;  4AT8 A;  5D62 A;  1GPJ A;  4X4V A;  4NKT A;  2DRB A;  2B56 A;  3HJ4 A;  4LEZ A;  4WH5 A;  2Q66 A;  4XJE A;  4X4U A;  4OAH A;  4O69 A;  4FHV A;  3OVA A;  4NXV A;  2ZH1 A;  4FH3 A;  4K98 A;  2ZH3 A;  3EF2 A;  4E7X A;  2ZH2 A;  2ZH8 A;  3HJ1 A;  3HIY A;  4AT7 A;  3NYB A;  5CFS A;  4OAI Z;  4K8V A;  1R8B A;  4UD4 A;  4X4T A;  4O67 A;  1R8C A;  4NXU A;  2ZH9 A;  4X4S A;  1FA0 A;  1Q79 A;  4K96 A;  2DR5 A;  4LEW A;  5D63 A;  4K9B A;  4K9A A;  4K99 A;  2B51 A;  4WOY A;  4X4R A;  4NXT A;  4OAF A;  4NKU A;  4LEV A;  2DVI A;  5CFU A;  1F5A A;  2DRA A;  4X4O A;  1UEV A;  2ZH6 A;  2ZHB A;  4X4N A;  3MCR A;  4EP7 A;  4WQL A;  1TFY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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