4O68A

Structure of human cyclic gmp-amp synthase (cgas)
Total Genus 114
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
114
sequence length
358
structure length
353
Chain Sequence
ASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFENPLSQFLEGEILSASKMLSKFRKIIKEEINDIKDTDVIMKRKRGGSPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKEGNGFQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVF
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cyclic GMP-AMP synthase
publication title The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 114
structure length 353
sequence length 358
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4o68A01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4o68A02
4JLXA 4O6AA 4NXXA 4KM5A 4AT7B 4K99A 4OAHA 4K8VA 4JLZA 4ATBB 4O67A 4OAIZ 4AT9B 4AT7A 4NXWA 4NXUA 4MKPA 4NXTA 4O68A 4WOYA 4LEYA 4ATBA 4KB6A 4O69A 4K96A 4AT8B 4K9AA 4K9BA 4K97A 4OAGA 4LEZA 4NXVA 4LEVA 4AT9A 4LEWA 4OAFA 4K98A 4AT8A
chains in the Genus database with same CATH superfamily
4YD2A 2FCLA 1ZQCA 4FHWA 4NKTA 4AT7B 4IQUA 1ZQLA 2BCSA 1JAJA 4XQ7A 4WBYA 1ZQHA 1MIYA 1ZQFA 5F2VO 4HX0A 4QZIA 5J0XA 3ISDA 3ER8C 3MDCA 4P4PA 2DR5A 4PGXA 1MQ3A 2PXIA 5J0WA 2B56A 3RH4A 7ICUA 4K9BA 4PGYA 4KLJA 1MIWA 4WCWA 4QZHA 4QZEA 5HRDA 5DB9A 3C2KA 1ZQPA 1ZQIA 4M9NA 4RPXA 8ICHA 4F5QA 3NYBA 4RQ0A 1ZQZA 2BCUA 4X4RA 4WC5A 2VANA 9ICRA 3OWGA 2O5AA 4KLQA 4EGWA 5BOLA 2GWSA 8ICQA 4MKPA 5DBAA 5CHGA 2ISOA 5J2EA 8ICEA 4K9AA 4M04A 4F5NA 4DOCA 1R89A 2BBHA 8ICFA 3TFSA 4WBZA 4RQ8A 1UEUA 4Z6DA 1OU5A 4WQLA 3RJHA 8ICNA 3GDXA 4I2AA 5CB1A 4TUPA 9ICCA 2IUBA 8ICUA 5HREA 1ZJMA 4O9MA 2NRKA 7ICSA 4NXWA 1ZQBA 8ICBA 4XRHA 4RWOA 4I2EA 4UB4A 1JQRA 1BPZA 4O69A 4WC6A 5IINA 3RJKA 4LT6A 4QZFA 4LEVA 4FH5A 4QZ8A 4P4OA 3C66A 3HIYA 3MGHA 5DBBA 5DB7A 3LQCB 2Q66A 4EEDA 3EF2A 8ICKA 4I2IA 9ICOA 9ICQA 3HJ1A 1NOMA 1ZQYA 4K99A 4I2JA 4QZAA 4NY8A 5HRGA 8ICSA 5IIIA 4JLZA 4QZCA 4UB5A 4IG8A 4O67A 3UXPA 8ICTA 3MBYA 3AU2A 9ICWA 4I0UA 5TZVA 1WOTA 2ZH5A 3RJFA 4X4NA 4TUQA 3JPSA 5CFSA 4TUSA 4RQ1A 4NXVA 4UD5A 4F5RA 1NO5A 5HRKA 4O5KA 4UB2A 4KLEA 5CP2A 3ERCC 3MCRA 4YN4A 4KLSA 1TV9A 5J0QA 2ISPA 2ZH3A 8ICZA 2BCRA 3H38A 1KDHA 4NLZA 1ZQJA 4LVSA 2IHOA 5J2HA 4KLTA 3RJIA 4YMOA 1ZQXA 3HX0A 2DVIA 8ICMA 3JPQA 2GAFD 3JPNA 4NLNA 4FHPA 4M9LA 5HC9A 4RWNA 4AT8A 2ZH9A 4NM2A 4NKUA 5CJ7A 9ICSA 1F5AA 9ICPA 2BE3A 4I28A 3JPOA 1Q78A 2O1PA 1BPDA 4OAIZ 4FO1A 3HWTA 1BPBA 4YD1A 4O68A 2B51A 4MFFA 2PFPA 3HJ4A 3UPQA 1MIVA 2ZH7A 8ICLA 2BCQA 5IIKA 4LEWA 3H39A 4X4VA 1ZQEA 4M47A 5HRBA 8ICXA 9ICJA 3RJGA 3UXOA 8ICGA 4O6AA 4KM5A 7ICTA 4PPXA 2ZHAA 3V72A 4OAHA 4YMMA 1BPYA 2DR9A 7ICEA 5CR0A 3WFPA 4WC4A 8ICJA 8ICIA 4WH5A 4RT3A 4P2HA 3WFOA 3ISCA 4KLHA 5J2IA 1RPLA 5DB8A 4MFAA 9ICMA 4K4GA 4M2YA 1R8BA 2ZH1A 4WC0A 1ZQOA 3OVBA 4UBBA 4PGQA 4X4SA 4RQ5A 4R64A 1ZQVA 4DOAA 3MGIA 1TFYA 4MFCA 4M9HA 3NWIA 2PFQA 1FA0A 2RFFA 1BPEA 3OUYA 7ICHA 1PX5A 4EBKA 5CWRA 5J2GA 3UQ2A 4X5VA 1R8AA 5CFUA 4K4HA 4RQ2A 5J2FA 4WQKA 1ZQKA 2DR8A 4I2FA 8ICYA 4UD4A 3OVSA 5D49A 4AT8B 3B0XA 3NKUA 5JTGA 3JPPA 3WFSC 4RQ3A 2IHMA 1ZQMA 3AU6A 3PMLA 2FMPA 2HHPA 3JCFA 4R66A 5D4BA 4K98A 4K4IA 5DEDA 4E7XA 5J2AA 5CA7A 4QZDA 1XSPA 9ICKA 5J29A 4FHVA 4QZ9A 3UPSA 4F5PA 3PHZA 4EBJA 4MF8A 3RH5A 3OVAA 5J0OA 4DO9A 4YCXA 4RQ6A 1Q79A 2BPCA 5HHIA 9ICLA 4MF2A 4KB6A 2M2WA 5EOZA 1ZQAA 2B4VA 3RJJA 1ZQDA 5J0TA 3AUOA 4KLFA 8ICVA 4EP7A 4I2DA 1ZQGA 2P66A 7ICRA 4KLLA 2ZH8A 3CK6A 3L9DA 4XA5A 4FO6A 5BPCA 4I2GA 3AQKA 2M2TA 5IIMA 2BPGA 4Z6FA 4IQWA 7ICJA 4WOYA 1UEVA 4XJEA 4XUSA 4Z6EA 4JWNA 4K96A 2I9GA 4K97A 4E80A 1TVAA 3ISBA 4AT9A 5HRHA 3OUYB 4EV6A 5J0RA 4RT2A 3C2MA 1RZTA 4KLOA 5IIOA 4O5CA 2HN1A 4PHPA 1HUZA 4N7RA 4X0AA 8ICPA 9ICHA 5D62A 1MQ2A 4FHXA 5J0PA 9ICFA 4WC2A 4DOBA 3K75D 2DRBA 3H3AA 3LK9A 3JZ0A 3C5FA 5IILA 4P4MA 4X4QA 4QZBA 9ICAA 4LEZA 3C2LA 4GXIA 4M9JA 4WC1A 1ZQWA 4E8FA 3HW8A 4OAFA 3OGUA 3V7JA 5D63A 4NXXA 1ZQNA 4RPZA 2ID1A 4I29A 4K8VA 4X0BA 3C5GA 4JWMA 5J2DA 2ZH2A 8ICWA 1JMSA 3JPRA 1GPJA 1HUOA 4I2BA 7ICMA 4UAWA 4FHYA 1VFGA 4I2HA 4UB1A 5DDYA 9ICVA 9ICIA 1V4AA 5HRIA 2BCVA 4NLKA 7ICKA 4OAGA 5CHEA 7ICFA 3C18A 3AQMA 4M9GA 5B3QA 1ZJNA 3V7LA 4M5DA 3PMNA 5J2BA 3AQNA 4X4PA 4PH5A 4IQTA 4KLGA 7ICVA 4RQ7A 5J2CA 4QZGA 3JYYA 5J2JA 4PHDA 1KEJA 4AT9B 3H37A 5DDMA 5J0YA 4RWQA 4ATBA 2M2UA 5D46A 4O5EA 8ICCA 4LZGA 9ICGA 5J0SA 7ICNA 7ICGA 4I2CA 2DRAA 3B0YA 5DKWA 2FMSA 2BPFA 2W9MA 5D61A 7ICLA 1UETA 4EEBA 4KLUA 1XSLA 7ICOA 1ZQTA 4RPYA 4I27A 5BOMA 3OV7A 4X4UA 4AT7A 2PFOA 3ER9B 5CFTA 3NVOA 4M0AA 3V7KA 4Z6CA 3RJEA 3TFRA 1YLQA 9ICXA 4UBCA 4GXJA 1ZQRA 1ZQQA 3PNCA 5DBCA 4UB3A 5HRLA 3WFRE 4FH3A 5J2KA 4S3NA 4WC7A 1ZQSA 3JPTA 4RQ4A 4RWPA 7ICQA 3UXNA 4R63A 4KLDA 3AQLA 9ICTA 5HHHA 3UQ0A 8ICRA 1ZQUA 4XQ8A 1BPXA 2DR7A 2ZH6A 4NXUA 4F5OA 4NXTA 1TFWA 4LEYA 1KNYA 4X4TA 5B3PA 4UAZA 2FMQA 8ICAA 4LZDA 3MDAA 2PFNA 4IQVA 4X4OA 4WC3A 4YMNA 2HN2A 4UAYA 3WFQE 4JLXA 4PHEA 8ICOA 9ICNA 1VJ7A 9ICBA 4KLIA 5HR9A 5J0UA 4TURA 2M2VA 4ATBB 3RH6A 1XSNA 2ZH4A 1R8CA 2GA9D 7ICIA 4NXZA 3K7DA 4KLMA 5HRFA 2PBEA 9ICUA 4PHAA 2BBJA 5IIJA 4R65A 2ZHBA 5DECA 4NM1A 4GXKA 9ICEA 5DB6A 7ICPA 2EWRA 1JN3A
chains in the Genus database with same CATH topology
4M5DA 2FCLA 3MCRA 4FHWA 4NKTA 4X4PA 4AT7B 4FHVA 3PHZA 2ZH3A 3OVAA 4HX0A 3ER8C 4AT9B 1Q79A 2DR5A 2IHOA 2B56A 4ATBA 4KB6A 4K9BA 2DVIA 2B4VA 2GAFD 4FHPA 2DRAA 4EP7A 4AT8A 2ZH9A 4NKUA 5D61A 1UETA 2ZH8A 3NYBA 1F5AA 4X4RA 1Q78A 2O1PA 3OWGA 3OV7A 4OAIZ 4FO1A 4X4UA 4AT7A 4MKPA 3ER9B 5CFTA 4O68A 2B51A 1UEVA 4WOYA 4XJEA 4K96A 4K9AA 3HJ4A 4K97A 4E80A 2ZH7A 1R89A 4AT9A 4LEWA 4X4VA 3OUYB 1UEUA 4O6AA 4KM5A 4WQLA 4N7RA 4FH3A 2ZHAA 4OAHA 5D62A 4FHXA 2DR9A 4WH5A 2EWRA 2DR7A 2DRBA 4NXWA 2ZH6A 4NXUA 4NXTA 1TFWA 1R8BA 2ZH1A 4LEYA 4O69A 4X4TA 5B3PA 4X4QA 3OVBA 4LEZA 4LT6A 4X4SA 4LEVA 4FH5A 3C66A 3HIYA 1TFYA 4X4OA 4E8FA 2Q66A 4OAFA 5D63A 4JLXA 3EF2A 4NXXA 3HJ1A 1FA0A 4K99A 4K8VA 3OUYA 4JLZA 2ZH2A 4ATBB 2ZH4A 4O67A 1GPJA 1R8CA 1R8AA 2GA9D 5CFUA 4FHYA 3K7DA 4WQKA 2DR8A 2ZH5A 4X4NA 3ERCC 4UD4A 3OVSA 4AT8B 5CFSA 3NKUA 2ZHBA 4OAGA 4NXVA 5CHEA 4UD5A 5B3QA 2HHPA 4K98A 4E7XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4JLX A;  4O6A A;  4NXX A;  4KM5 A;  4AT7 B;  4K99 A;  4OAH A;  4K8V A;  4JLZ A;  4ATB B;  4O67 A;  4OAI Z;  4AT9 B;  4AT7 A;  4NXW A;  4NXU A;  4MKP A;  4NXT A;  4O68 A;  4WOY A;  4LEY A;  4ATB A;  4KB6 A;  4O69 A;  4K96 A;  4AT8 B;  4K9A A;  4K9B A;  4K97 A;  4OAG A;  4LEZ A;  4NXV A;  4LEV A;  4AT9 A;  4LEW A;  4OAF A;  4K98 A;  4AT8 A; 
#chains in the Genus database with same CATH topology
 4YD2 A;  2FCL A;  1ZQC A;  4FHW A;  4NKT A;  4AT7 B;  4IQU A;  1ZQL A;  2BCS A;  1JAJ A;  4XQ7 A;  4WBY A;  1ZQH A;  1MIY A;  1ZQF A;  5F2V O;  4HX0 A;  4QZI A;  5J0X A;  3ISD A;  3ER8 C;  3MDC A;  4P4P A;  2DR5 A;  4PGX A;  1MQ3 A;  2PXI A;  5J0W A;  2B56 A;  3RH4 A;  7ICU A;  4K9B A;  4PGY A;  4KLJ A;  1MIW A;  4WCW A;  4QZH A;  4QZE A;  5HRD A;  5DB9 A;  3C2K A;  1ZQP A;  1ZQI A;  4M9N A;  4RPX A;  8ICH A;  4F5Q A;  3NYB A;  4RQ0 A;  1ZQZ A;  2BCU A;  4X4R A;  4WC5 A;  2VAN A;  9ICR A;  3OWG A;  2O5A A;  4KLQ A;  4EGW A;  5BOL A;  2GWS A;  8ICQ A;  4MKP A;  5DBA A;  5CHG A;  2ISO A;  5J2E A;  8ICE A;  4K9A A;  4M04 A;  4F5N A;  4DOC A;  1R89 A;  2BBH A;  8ICF A;  3TFS A;  4WBZ A;  4RQ8 A;  1UEU A;  4Z6D A;  1OU5 A;  4WQL A;  3RJH A;  8ICN A;  3GDX A;  4I2A A;  5CB1 A;  4TUP A;  9ICC A;  2IUB A;  8ICU A;  5HRE A;  1ZJM A;  4O9M A;  2NRK A;  7ICS A;  4NXW A;  1ZQB A;  8ICB A;  4XRH A;  4RWO A;  4I2E A;  4UB4 A;  1JQR A;  1BPZ A;  4O69 A;  4WC6 A;  5IIN A;  3RJK A;  4LT6 A;  4QZF A;  4LEV A;  4FH5 A;  4QZ8 A;  4P4O A;  3C66 A;  3HIY A;  3MGH A;  5DBB A;  5DB7 A;  3LQC B;  2Q66 A;  4EED A;  3EF2 A;  8ICK A;  4I2I A;  9ICO A;  9ICQ A;  3HJ1 A;  1NOM A;  1ZQY A;  4K99 A;  4I2J A;  4QZA A;  4NY8 A;  5HRG A;  8ICS A;  5III A;  4JLZ A;  4QZC A;  4UB5 A;  4IG8 A;  4O67 A;  3UXP A;  8ICT A;  3MBY A;  3AU2 A;  9ICW A;  4I0U A;  5TZV A;  1WOT A;  2ZH5 A;  3RJF A;  4X4N A;  4TUQ A;  3JPS A;  5CFS A;  4TUS A;  4RQ1 A;  4NXV A;  4UD5 A;  4F5R A;  1NO5 A;  5HRK A;  4O5K A;  4UB2 A;  4KLE A;  5CP2 A;  3ERC C;  3MCR A;  4YN4 A;  4KLS A;  1TV9 A;  5J0Q A;  2ISP A;  2ZH3 A;  8ICZ A;  2BCR A;  3H38 A;  1KDH A;  4NLZ A;  1ZQJ A;  4LVS A;  2IHO A;  5J2H A;  4KLT A;  3RJI A;  4YMO A;  1ZQX A;  3HX0 A;  2DVI A;  8ICM A;  3JPQ A;  2GAF D;  3JPN A;  4NLN A;  4FHP A;  4M9L A;  5HC9 A;  4RWN A;  4AT8 A;  2ZH9 A;  4NM2 A;  4NKU A;  5CJ7 A;  9ICS A;  1F5A A;  9ICP A;  2BE3 A;  4I28 A;  3JPO A;  1Q78 A;  2O1P A;  1BPD A;  4OAI Z;  4FO1 A;  3HWT A;  1BPB A;  4YD1 A;  4O68 A;  2B51 A;  4MFF A;  2PFP A;  3HJ4 A;  3UPQ A;  1MIV A;  2ZH7 A;  8ICL A;  2BCQ A;  5IIK A;  4LEW A;  3H39 A;  4X4V A;  1ZQE A;  4M47 A;  5HRB A;  8ICX A;  9ICJ A;  3RJG A;  3UXO A;  8ICG A;  4O6A A;  4KM5 A;  7ICT A;  4PPX A;  2ZHA A;  3V72 A;  4OAH A;  4YMM A;  1BPY A;  2DR9 A;  7ICE A;  5CR0 A;  3WFP A;  4WC4 A;  8ICJ A;  8ICI A;  4WH5 A;  4RT3 A;  4P2H A;  3WFO A;  3ISC A;  4KLH A;  5J2I A;  1RPL A;  5DB8 A;  4MFA A;  9ICM A;  4K4G A;  4M2Y A;  1R8B A;  2ZH1 A;  4WC0 A;  1ZQO A;  3OVB A;  4UBB A;  4PGQ A;  4X4S A;  4RQ5 A;  4R64 A;  1ZQV A;  4DOA A;  3MGI A;  1TFY A;  4MFC A;  4M9H A;  3NWI A;  2PFQ A;  1FA0 A;  2RFF A;  1BPE A;  3OUY A;  7ICH A;  1PX5 A;  4EBK A;  5CWR A;  5J2G A;  3UQ2 A;  4X5V A;  1R8A A;  5CFU A;  4K4H A;  4RQ2 A;  5J2F A;  4WQK A;  1ZQK A;  2DR8 A;  4I2F A;  8ICY A;  4UD4 A;  3OVS A;  5D49 A;  4AT8 B;  3B0X A;  3NKU A;  5JTG A;  3JPP A;  3WFS C;  4RQ3 A;  2IHM A;  1ZQM A;  3AU6 A;  3PML A;  2FMP A;  2HHP A;  3JCF A;  4R66 A;  5D4B A;  4K98 A;  4K4I A;  5DED A;  4E7X A;  5J2A A;  5CA7 A;  4QZD A;  1XSP A;  9ICK A;  5J29 A;  4FHV A;  4QZ9 A;  3UPS A;  4F5P A;  3PHZ A;  4EBJ A;  4MF8 A;  3RH5 A;  3OVA A;  5J0O A;  4DO9 A;  4YCX A;  4RQ6 A;  1Q79 A;  2BPC A;  5HHI A;  9ICL A;  4MF2 A;  4KB6 A;  2M2W A;  5EOZ A;  1ZQA A;  2B4V A;  3RJJ A;  1ZQD A;  5J0T A;  3AUO A;  4KLF A;  8ICV A;  4EP7 A;  4I2D A;  1ZQG A;  2P66 A;  7ICR A;  4KLL A;  2ZH8 A;  3CK6 A;  3L9D A;  4XA5 A;  4FO6 A;  5BPC A;  4I2G A;  3AQK A;  2M2T A;  5IIM A;  2BPG A;  4Z6F A;  4IQW A;  7ICJ A;  4WOY A;  1UEV A;  4XJE A;  4XUS A;  4Z6E A;  4JWN A;  4K96 A;  2I9G A;  4K97 A;  4E80 A;  1TVA A;  3ISB A;  4AT9 A;  5HRH A;  3OUY B;  4EV6 A;  5J0R A;  4RT2 A;  3C2M A;  1RZT A;  4KLO A;  5IIO A;  4O5C A;  2HN1 A;  4PHP A;  1HUZ A;  4N7R A;  4X0A A;  8ICP A;  9ICH A;  5D62 A;  1MQ2 A;  4FHX A;  5J0P A;  9ICF A;  4WC2 A;  4DOB A;  3K75 D;  2DRB A;  3H3A A;  3LK9 A;  3JZ0 A;  3C5F A;  5IIL A;  4P4M A;  4X4Q A;  4QZB A;  9ICA A;  4LEZ A;  3C2L A;  4GXI A;  4M9J A;  4WC1 A;  1ZQW A;  4E8F A;  3HW8 A;  4OAF A;  3OGU A;  3V7J A;  5D63 A;  4NXX A;  1ZQN A;  4RPZ A;  2ID1 A;  4I29 A;  4K8V A;  4X0B A;  3C5G A;  4JWM A;  5J2D A;  2ZH2 A;  8ICW A;  1JMS A;  3JPR A;  1GPJ A;  1HUO A;  4I2B A;  7ICM A;  4UAW A;  4FHY A;  1VFG A;  4I2H A;  4UB1 A;  5DDY A;  9ICV A;  9ICI A;  1V4A A;  5HRI A;  2BCV A;  4NLK A;  7ICK A;  4OAG A;  5CHE A;  7ICF A;  3C18 A;  3AQM A;  4M9G A;  5B3Q A;  1ZJN A;  3V7L A;  4M5D A;  3PMN A;  5J2B A;  3AQN A;  4X4P A;  4PH5 A;  4IQT A;  4KLG A;  7ICV A;  4RQ7 A;  5J2C A;  4QZG A;  3JYY A;  5J2J A;  4PHD A;  1KEJ A;  4AT9 B;  3H37 A;  5DDM A;  5J0Y A;  4RWQ A;  4ATB A;  2M2U A;  5D46 A;  4O5E A;  8ICC A;  4LZG A;  9ICG A;  5J0S A;  7ICN A;  7ICG A;  4I2C A;  2DRA A;  3B0Y A;  5DKW A;  2FMS A;  2BPF A;  2W9M A;  5D61 A;  7ICL A;  1UET A;  4EEB A;  4KLU A;  1XSL A;  7ICO A;  1ZQT A;  4RPY A;  4I27 A;  5BOM A;  3OV7 A;  4X4U A;  4AT7 A;  2PFO A;  3ER9 B;  5CFT A;  3NVO A;  4M0A A;  3V7K A;  4Z6C A;  3RJE A;  3TFR A;  1YLQ A;  9ICX A;  4UBC A;  4GXJ A;  1ZQR A;  1ZQQ A;  3PNC A;  5DBC A;  4UB3 A;  5HRL A;  3WFR E;  4FH3 A;  5J2K A;  4S3N A;  4WC7 A;  1ZQS A;  3JPT A;  4RQ4 A;  4RWP A;  7ICQ A;  3UXN A;  4R63 A;  4KLD A;  3AQL A;  9ICT A;  5HHH A;  3UQ0 A;  8ICR A;  1ZQU A;  4XQ8 A;  1BPX A;  2DR7 A;  2ZH6 A;  4NXU A;  4F5O A;  4NXT A;  1TFW A;  4LEY A;  1KNY A;  4X4T A;  5B3P A;  4UAZ A;  2FMQ A;  8ICA A;  4LZD A;  3MDA A;  2PFN A;  4IQV A;  4X4O A;  4WC3 A;  4YMN A;  2HN2 A;  4UAY A;  3WFQ E;  4JLX A;  4PHE A;  8ICO A;  9ICN A;  1VJ7 A;  9ICB A;  4KLI A;  5HR9 A;  5J0U A;  4TUR A;  2M2V A;  4ATB B;  3RH6 A;  1XSN A;  2ZH4 A;  1R8C A;  2GA9 D;  7ICI A;  4NXZ A;  3K7D A;  4KLM A;  5HRF A;  2PBE A;  9ICU A;  4PHA A;  2BBJ A;  5IIJ A;  4R65 A;  2ZHB A;  5DEC A;  4NM1 A;  4GXK A;  9ICE A;  5DB6 A;  7ICP A;  2EWR A;  1JN3 A; 
#chains in the Genus database with same CATH homology
 4M5D A;  2FCL A;  3MCR A;  4FHW A;  4NKT A;  4X4P A;  4AT7 B;  4FHV A;  3PHZ A;  2ZH3 A;  3OVA A;  4HX0 A;  3ER8 C;  4AT9 B;  1Q79 A;  2DR5 A;  2IHO A;  2B56 A;  4ATB A;  4KB6 A;  4K9B A;  2DVI A;  2B4V A;  2GAF D;  4FHP A;  2DRA A;  4EP7 A;  4AT8 A;  2ZH9 A;  4NKU A;  5D61 A;  1UET A;  2ZH8 A;  3NYB A;  1F5A A;  4X4R A;  1Q78 A;  2O1P A;  3OWG A;  3OV7 A;  4OAI Z;  4FO1 A;  4X4U A;  4AT7 A;  4MKP A;  3ER9 B;  5CFT A;  4O68 A;  2B51 A;  1UEV A;  4WOY A;  4XJE A;  4K96 A;  4K9A A;  3HJ4 A;  4K97 A;  4E80 A;  2ZH7 A;  1R89 A;  4AT9 A;  4LEW A;  4X4V A;  3OUY B;  1UEU A;  4O6A A;  4KM5 A;  4WQL A;  4N7R A;  4FH3 A;  2ZHA A;  4OAH A;  5D62 A;  4FHX A;  2DR9 A;  4WH5 A;  2EWR A;  2DR7 A;  2DRB A;  4NXW A;  2ZH6 A;  4NXU A;  4NXT A;  1TFW A;  1R8B A;  2ZH1 A;  4LEY A;  4O69 A;  4X4T A;  5B3P A;  4X4Q A;  3OVB A;  4LEZ A;  4LT6 A;  4X4S A;  4LEV A;  4FH5 A;  3C66 A;  3HIY A;  1TFY A;  4X4O A;  4E8F A;  2Q66 A;  4OAF A;  5D63 A;  4JLX A;  3EF2 A;  4NXX A;  3HJ1 A;  1FA0 A;  4K99 A;  4K8V A;  3OUY A;  4JLZ A;  2ZH2 A;  4ATB B;  2ZH4 A;  4O67 A;  1GPJ A;  1R8C A;  1R8A A;  2GA9 D;  5CFU A;  4FHY A;  3K7D A;  4WQK A;  2DR8 A;  2ZH5 A;  4X4N A;  3ERC C;  4UD4 A;  3OVS A;  4AT8 B;  5CFS A;  3NKU A;  2ZHB A;  4OAG A;  4NXV A;  5CHE A;  4UD5 A;  5B3Q A;  2HHP A;  4K98 A;  4E7X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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