4O69A

Human cyclic gmp-amp synthase (cgas) in complex with sulfate ion
Total Genus 128
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
128
sequence length
362
structure length
353
Chain Sequence
MGASKLRAVLEKLKLSRDDISTAAGMVKGVVDHLLLRLKCDSAFRGVGLLNTGSYYEHVKISAPNEFDVMFKLEVPRIQLEEYSNTRAYYFVKFKRNPKENPLSQFLEGEILSASKMLSKFRKIIKEEINDITDVIMKRKRGPAVTLLISEKISVDITLALESKSSWPASTQEGLRIQNWLSAKVRKQLRLKPFYLVPKHAKQEETWRLSFSHIEKEILNNHGKSKTCCENKEEKCCRKDCLKLMKYLLEQLKERFKDKKHLDKFSSYHVKTAFFHVCTQNPQDSQWDRKDLGLCFDNCVTYFLQCLRTEKLENYFIPEFNLFSSNLIDKRSKEFLTKQIEYERNNEFPVFDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Cyclic GMP-AMP synthase
publication title The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Transferase
total genus 128
structure length 353
sequence length 362
ec nomenclature ec 2.7.7.86: Cyclic GMP-AMP synthase.
pdb deposition date 2013-12-20

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03281 Mab-21 Mab-21 protein
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1410.40 Mainly Alpha Orthogonal Bundle Poly(a)-polymerase, middle domain Poly(a)-polymerase, middle domain 4o69A01
3.30.460.90 Alpha Beta 2-Layer Sandwich Beta Polymerase; domain 2 Beta Polymerase; domain 2 4o69A02
4NXXA 4AT8A 4ATBB 4MKPA 4O6AA 4OAFA 4OAHA 4KM5A 4NXWA 4LEWA 4AT7B 4AT9B 4K98A 4LEYA 4ATBA 4K9AA 4O67A 4K97A 4JLZA 4K8VA 4AT7A 4K96A 4O68A 4JLXA 4OAIZ 4KB6A 4OAGA 4NXUA 4AT9A 4WOYA 4AT8B 4LEVA 4NXVA 4K99A 4NXTA 4O69A 4K9BA 4LEZA
chains in the Genus database with same CATH superfamily
4IQUA 7ICPA 4YCXA 4R64A 4FHXA 7ICKA 3NKUA 1ZQJA 1BPYA 4RWNA 2BE3A 4AT7B 4PHDA 1JAJA 7ICSA 4RPZA 5HREA 5HRBA 3NVOA 9ICEA 9ICJA 2O5AA 3AQKA 5IIJA 8ICBA 3HX0A 4XJEA 4FH5A 1ZQVA 4NY8A 2IHOA 1PX5A 3UQ0A 5J0RA 4UD5A 1ZQNA 1R8AA 3C66A 4LEZA 4YMMA 2PXIA 4F5RA 9ICGA 4AT8A 4MKPA 3WFSC 1JQRA 2HN2A 1KNYA 5J0YA 5B3PA 5DB6A 3ER9B 4KLQA 3PHZA 4AT9B 7ICLA 4HX0A 4UAYA 4O9MA 8ICVA 4I0UA 4DOCA 4QZDA 4K96A 1NO5A 4F5PA 1Q79A 5DBBA 4QZGA 2M2TA 4NXUA 4UB4A 1JMSA 5HRGA 1ZQPA 4UD4A 3WFOA 4LEVA 5HR9A 3HJ4A 4QZAA 5J2EA 9ICVA 3LK9A 1XSPA 4UBBA 7ICFA 3RH4A 5CA7A 4MF8A 5DDMA 1BPDA 4GXKA 1RZTA 5DB9A 3AU2A 4QZCA 4EBJA 3UXOA 2HHPA 5D61A 4X4VA 4XA5A 5J0UA 4I2BA 9ICMA 8ICWA 4PHAA 3PMLA 8ICZA 2ZH5A 3OVSA 4TUSA 2BCUA 2ID1A 3JPTA 4F5NA 8ICSA 5J0SA 2ZH3A 4I2EA 5CHEA 9ICKA 5DEDA 2M2VA 1TVAA 5DB7A 3WFRE 7ICUA 4GXJA 4WC7A 5JTGA 8ICNA 4JLXA 4R65A 4RPXA 1ZQSA 1ZQZA 3C18A 3C5GA 2DVIA 3ISDA 4X5VA 3OUYB 5IIIA 1BPZA 8ICJA 5CHGA 4KLOA 4NXXA 2ISPA 4MF2A 1ZQIA 1V4AA 5DBCA 2B4VA 5IINA 4NM1A 2BBHA 1BPXA 3RJIA 8ICFA 9ICWA 4YD1A 5HRKA 4KLHA 7ICMA 8ICHA 1XSNA 8ICTA 4FHWA 4QZIA 4KLSA 5J0XA 4K9AA 3RH5A 9ICIA 5HHIA 2DR7A 4Z6EA 5J0QA 2BCRA 4WC1A 4EGWA 1F5AA 5IIMA 4IQWA 1MIVA 4I27A 3HWTA 2I9GA 2FMSA 4NLZA 4NXZA 3RJHA 1ZQWA 1TFYA 2ZH6A 4M2YA 9ICNA 4LEYA 1MQ3A 1VJ7A 3RJEA 1BPBA 2NRKA 4RQ3A 3H39A 4UB1A 3CK6A 9ICRA 5CFUA 4OAGA 1KEJA 4AT9A 3C5FA 4I2HA 4LZGA 4Z6CA 2ZH1A 4NXTA 5IILA 4RPYA 3JPNA 5IIOA 7ICTA 4NLNA 1ZQAA 2EWRA 7ICOA 1MQ2A 4X4UA 5J29A 2B51A 4M47A 4M5DA 2BCVA 3OGUA 5B3QA 5J2CA 4OAIZ 1R89A 3RJJA 4IQVA 4EEDA 4E8FA 4WC2A 4DOBA 2Q66A 3AQLA 1TFWA 4XRHA 2ZHAA 1MIYA 5J0TA 4FHYA 4K9BA 3NWIA 4GXIA 4ATBB 3K75D 4M9HA 3OWGA 2O1PA 3C2KA 3PNCA 7ICEA 2ZHBA 2FMQA 2GA9D 2W9MA 3TFRA 3B0YA 4NM2A 2PFOA 4KLGA 3UQ2A 4P2HA 3RH6A 2DRAA 4WC3A 4MFAA 3MGHA 1OU5A 5CR0A 3AUOA 5D63A 1ZQXA 3ISCA 1KDHA 3PMNA 9ICCA 5D4BA 2M2WA 4RQ5A 3V7KA 5J0OA 4LZDA 4OAFA 4PGQA 5F2VO 4KLLA 5HRFA 5CFSA 4LEWA 5J2HA 5HRDA 5D49A 1ZQEA 3HW8A 3JZ0A 3OUYA 4X0BA 3JYYA 3RJGA 2ZH2A 5CP2A 1XSLA 3GDXA 1WOTA 5J2JA 5DKWA 1ZQFA 1ZQDA 1ZQLA 4RQ4A 4LVSA 4K97A 3L9DA 4JLZA 4PGXA 4XUSA 3V7JA 4M04A 2RFFA 1ZQYA 7ICVA 9ICFA 3UXNA 5J2IA 2PBEA 4KLJA 5J2KA 4WC0A 4WCWA 4WC6A 2BCSA 4X4QA 1BPEA 3MDCA 4P4MA 9ICPA 4X4RA 3WFQE 4PPXA 5HC9A 4I2FA 1ZQMA 8ICKA 3JPSA 2ISOA 4DO9A 4EV6A 2PFNA 7ICIA 3OVBA 4IQTA 4WQLA 4X4SA 4WC5A 2GWSA 3RJFA 4O68A 4RQ1A 7ICJA 1HUZA 4RQ6A 4K4GA 4UAZA 1GPJA 5CWRA 8ICUA 4O69A 4YD2A 4MFFA 2M2UA 8ICCA 5J2DA 9ICXA 1JN3A 1ZQBA 3MCRA 4F5QA 3C2MA 4N7RA 1FA0A 4O5KA 2ZH9A 5J0WA 3EF2A 4WH5A 5DB8A 4RQ8A 3V7LA 4K98A 4E80A 8ICMA 4UB3A 3AQMA 3AQNA 1UEUA 5J2FA 5J2BA 4I29A 4O67A 1VFGA 8ICIA 8ICEA 4KLUA 4R63A 4QZHA 1HUOA 3RJKA 4FHVA 4UB2A 4TURA 1R8BA 3JPOA 1UEVA 2PFQA 1MIWA 4LT6A 2ZH8A 4QZEA 1ZQKA 4Z6FA 4XQ8A 9ICSA 3ERCC 3MDAA 4EBKA 4PH5A 3JPQA 8ICYA 4YMOA 4JWMA 1NOMA 4NKTA 4ATBA 4K4HA 4NLKA 4WC4A 3MGIA 8ICLA 5DBAA 4RWPA 3ER8C 4UBCA 4KB6A 4PGYA 4E7XA 4WBZA 4I2AA 7ICQA 5DDYA 2BPGA 7ICGA 3V72A 4NXVA 9ICOA 3H38A 4I2IA 5EOZA 9ICTA 4WBYA 3HJ1A 4EP7A 1UETA 4RWQA 4I2DA 2GAFD 4M9JA 4P4PA 2DR9A 2DRBA 3AU6A 4EEBA 5J2GA 4UB5A 3C2LA 4KLDA 5CJ7A 4FO1A 4YMNA 1R8CA 4R66A 1Q78A 2BCQA 5CFTA 3ISBA 4AT8B 5BOMA 5J0PA 4XQ7A 2DR5A 4Z6DA 9ICLA 4FH3A 3LQCB 9ICAA 9ICQA 1ZJMA 4I2CA 5J2AA 9ICHA 4M9GA 4KLMA 3JPRA 4O6AA 1ZQQA 4OAHA 4KM5A 4X0AA 2P66A 3UPQA 3H3AA 8ICAA 7ICNA 1ZQCA 1ZQTA 9ICUA 4FHPA 8ICPA 5IIKA 2B56A 4NKUA 1RPLA 3UPSA 4K8VA 4IG8A 2VANA 4O5CA 4QZ8A 3JCFA 4I28A 4RQ2A 4UAWA 7ICRA 8ICXA 4F5OA 4X4NA 3JPPA 9ICBA 5HHHA 4FO6A 1ZQUA 4P4OA 4M9LA 3WFPA 4K99A 4TUPA 4RWOA 4TUQA 2IUBA 4X4PA 3OV7A 4KLTA 3HIYA 1ZQGA 2BBJA 2ZH4A 5HRHA 2IHMA 4RQ0A 3NYBA 5DECA 3H37A 8ICQA 4KLFA 4I2JA 5TZVA 5BPCA 4X4OA 8ICOA 7ICHA 3K7DA 4RT3A 4RT2A 5D46A 1ZQOA 8ICGA 4PHPA 3OVAA 3UXPA 4O5EA 3B0XA 4S3NA 4MFCA 4K4IA 5CB1A 5D62A 4RQ7A 4X4TA 5BOLA 2PFPA 8ICRA 4NXWA 4M9NA 4YN4A 4KLIA 5HRLA 1YLQA 4I2GA 1ZQRA 2DR8A 2ZH7A 2HN1A 2FMPA 1TV9A 5HRIA 4AT7A 4QZBA 2FCLA 4M0AA 4WOYA 1ZQHA 4KLEA 4DOAA 3TFSA 3MBYA 4WQKA 2BPCA 4QZFA 4PHEA 4JWNA 1ZJNA 4QZ9A 2BPFA
chains in the Genus database with same CATH topology
4NXXA 4EP7A 1UETA 2GAFD 4FHXA 4OAFA 2B4VA 2DR9A 2DRBA 3NKUA 5CFSA 4LEWA 4AT7B 3OUYA 2ZH2A 4FHWA 4FO1A 4K9AA 1R8CA 1Q78A 4K97A 4JLZA 2DR7A 5CFTA 4AT8B 4XJEA 4FH5A 1F5AA 2DR5A 2IHOA 4FH3A 4UD5A 1R8AA 3C66A 4LEZA 4AT8A 4MKPA 4O6AA 4X4QA 4OAHA 4KM5A 4X4RA 5B3PA 3ER9B 3PHZA 1TFYA 2ZH6A 4AT9B 4FHPA 4HX0A 3OVBA 4LEYA 2B56A 4WQLA 4X4SA 4NKUA 4K8VA 4K96A 1Q79A 4O68A 5CFUA 4OAGA 4NXUA 4AT9A 4UD4A 4LEVA 1GPJA 3HJ4A 4X4NA 2ZH1A 4K99A 4NXTA 3MCRA 4X4PA 3OV7A 4N7RA 3HIYA 1FA0A 2ZH4A 2ZH9A 3EF2A 2EWRA 4WH5A 4K98A 3NYBA 4X4UA 4E80A 2B51A 4M5DA 2HHPA 1UEUA 5D61A 4O67A 5B3QA 4X4VA 4X4OA 4OAIZ 1R89A 4E8FA 3K7DA 2Q66A 2ZH5A 1TFWA 4FHVA 3OVSA 3OVAA 2ZHAA 4FHYA 4K9BA 1R8BA 5D62A 1UEVA 4ATBB 2ZH3A 4LT6A 4X4TA 2ZH8A 3OWGA 2O1PA 5CHEA 4NXWA 2ZHBA 3ERCC 2GA9D 4NKTA 4ATBA 2DR8A 2ZH7A 4AT7A 2DRAA 2FCLA 4JLXA 3ER8C 4KB6A 4E7XA 4WOYA 5D63A 4NXVA 4WQKA 2DVIA 3OUYB 4O69A 3HJ1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4NXX A;  4AT8 A;  4ATB B;  4MKP A;  4O6A A;  4OAF A;  4OAH A;  4KM5 A;  4NXW A;  4LEW A;  4AT7 B;  4AT9 B;  4K98 A;  4LEY A;  4ATB A;  4K9A A;  4O67 A;  4K97 A;  4JLZ A;  4K8V A;  4AT7 A;  4K96 A;  4O68 A;  4JLX A;  4OAI Z;  4KB6 A;  4OAG A;  4NXU A;  4AT9 A;  4WOY A;  4AT8 B;  4LEV A;  4NXV A;  4K99 A;  4NXT A;  4O69 A;  4K9B A;  4LEZ A; 
#chains in the Genus database with same CATH topology
 4IQU A;  7ICP A;  4YCX A;  4R64 A;  4FHX A;  7ICK A;  3NKU A;  1ZQJ A;  1BPY A;  4RWN A;  2BE3 A;  4AT7 B;  4PHD A;  1JAJ A;  7ICS A;  4RPZ A;  5HRE A;  5HRB A;  3NVO A;  9ICE A;  9ICJ A;  2O5A A;  3AQK A;  5IIJ A;  8ICB A;  3HX0 A;  4XJE A;  4FH5 A;  1ZQV A;  4NY8 A;  2IHO A;  1PX5 A;  3UQ0 A;  5J0R A;  4UD5 A;  1ZQN A;  1R8A A;  3C66 A;  4LEZ A;  4YMM A;  2PXI A;  4F5R A;  9ICG A;  4AT8 A;  4MKP A;  3WFS C;  1JQR A;  2HN2 A;  1KNY A;  5J0Y A;  5B3P A;  5DB6 A;  3ER9 B;  4KLQ A;  3PHZ A;  4AT9 B;  7ICL A;  4HX0 A;  4UAY A;  4O9M A;  8ICV A;  4I0U A;  4DOC A;  4QZD A;  4K96 A;  1NO5 A;  4F5P A;  1Q79 A;  5DBB A;  4QZG A;  2M2T A;  4NXU A;  4UB4 A;  1JMS A;  5HRG A;  1ZQP A;  4UD4 A;  3WFO A;  4LEV A;  5HR9 A;  3HJ4 A;  4QZA A;  5J2E A;  9ICV A;  3LK9 A;  1XSP A;  4UBB A;  7ICF A;  3RH4 A;  5CA7 A;  4MF8 A;  5DDM A;  1BPD A;  4GXK A;  1RZT A;  5DB9 A;  3AU2 A;  4QZC A;  4EBJ A;  3UXO A;  2HHP A;  5D61 A;  4X4V A;  4XA5 A;  5J0U A;  4I2B A;  9ICM A;  8ICW A;  4PHA A;  3PML A;  8ICZ A;  2ZH5 A;  3OVS A;  4TUS A;  2BCU A;  2ID1 A;  3JPT A;  4F5N A;  8ICS A;  5J0S A;  2ZH3 A;  4I2E A;  5CHE A;  9ICK A;  5DED A;  2M2V A;  1TVA A;  5DB7 A;  3WFR E;  7ICU A;  4GXJ A;  4WC7 A;  5JTG A;  8ICN A;  4JLX A;  4R65 A;  4RPX A;  1ZQS A;  1ZQZ A;  3C18 A;  3C5G A;  2DVI A;  3ISD A;  4X5V A;  3OUY B;  5III A;  1BPZ A;  8ICJ A;  5CHG A;  4KLO A;  4NXX A;  2ISP A;  4MF2 A;  1ZQI A;  1V4A A;  5DBC A;  2B4V A;  5IIN A;  4NM1 A;  2BBH A;  1BPX A;  3RJI A;  8ICF A;  9ICW A;  4YD1 A;  5HRK A;  4KLH A;  7ICM A;  8ICH A;  1XSN A;  8ICT A;  4FHW A;  4QZI A;  4KLS A;  5J0X A;  4K9A A;  3RH5 A;  9ICI A;  5HHI A;  2DR7 A;  4Z6E A;  5J0Q A;  2BCR A;  4WC1 A;  4EGW A;  1F5A A;  5IIM A;  4IQW A;  1MIV A;  4I27 A;  3HWT A;  2I9G A;  2FMS A;  4NLZ A;  4NXZ A;  3RJH A;  1ZQW A;  1TFY A;  2ZH6 A;  4M2Y A;  9ICN A;  4LEY A;  1MQ3 A;  1VJ7 A;  3RJE A;  1BPB A;  2NRK A;  4RQ3 A;  3H39 A;  4UB1 A;  3CK6 A;  9ICR A;  5CFU A;  4OAG A;  1KEJ A;  4AT9 A;  3C5F A;  4I2H A;  4LZG A;  4Z6C A;  2ZH1 A;  4NXT A;  5IIL A;  4RPY A;  3JPN A;  5IIO A;  7ICT A;  4NLN A;  1ZQA A;  2EWR A;  7ICO A;  1MQ2 A;  4X4U A;  5J29 A;  2B51 A;  4M47 A;  4M5D A;  2BCV A;  3OGU A;  5B3Q A;  5J2C A;  4OAI Z;  1R89 A;  3RJJ A;  4IQV A;  4EED A;  4E8F A;  4WC2 A;  4DOB A;  2Q66 A;  3AQL A;  1TFW A;  4XRH A;  2ZHA A;  1MIY A;  5J0T A;  4FHY A;  4K9B A;  3NWI A;  4GXI A;  4ATB B;  3K75 D;  4M9H A;  3OWG A;  2O1P A;  3C2K A;  3PNC A;  7ICE A;  2ZHB A;  2FMQ A;  2GA9 D;  2W9M A;  3TFR A;  3B0Y A;  4NM2 A;  2PFO A;  4KLG A;  3UQ2 A;  4P2H A;  3RH6 A;  2DRA A;  4WC3 A;  4MFA A;  3MGH A;  1OU5 A;  5CR0 A;  3AUO A;  5D63 A;  1ZQX A;  3ISC A;  1KDH A;  3PMN A;  9ICC A;  5D4B A;  2M2W A;  4RQ5 A;  3V7K A;  5J0O A;  4LZD A;  4OAF A;  4PGQ A;  5F2V O;  4KLL A;  5HRF A;  5CFS A;  4LEW A;  5J2H A;  5HRD A;  5D49 A;  1ZQE A;  3HW8 A;  3JZ0 A;  3OUY A;  4X0B A;  3JYY A;  3RJG A;  2ZH2 A;  5CP2 A;  1XSL A;  3GDX A;  1WOT A;  5J2J A;  5DKW A;  1ZQF A;  1ZQD A;  1ZQL A;  4RQ4 A;  4LVS A;  4K97 A;  3L9D A;  4JLZ A;  4PGX A;  4XUS A;  3V7J A;  4M04 A;  2RFF A;  1ZQY A;  7ICV A;  9ICF A;  3UXN A;  5J2I A;  2PBE A;  4KLJ A;  5J2K A;  4WC0 A;  4WCW A;  4WC6 A;  2BCS A;  4X4Q A;  1BPE A;  3MDC A;  4P4M A;  9ICP A;  4X4R A;  3WFQ E;  4PPX A;  5HC9 A;  4I2F A;  1ZQM A;  8ICK A;  3JPS A;  2ISO A;  4DO9 A;  4EV6 A;  2PFN A;  7ICI A;  3OVB A;  4IQT A;  4WQL A;  4X4S A;  4WC5 A;  2GWS A;  3RJF A;  4O68 A;  4RQ1 A;  7ICJ A;  1HUZ A;  4RQ6 A;  4K4G A;  4UAZ A;  1GPJ A;  5CWR A;  8ICU A;  4O69 A;  4YD2 A;  4MFF A;  2M2U A;  8ICC A;  5J2D A;  9ICX A;  1JN3 A;  1ZQB A;  3MCR A;  4F5Q A;  3C2M A;  4N7R A;  1FA0 A;  4O5K A;  2ZH9 A;  5J0W A;  3EF2 A;  4WH5 A;  5DB8 A;  4RQ8 A;  3V7L A;  4K98 A;  4E80 A;  8ICM A;  4UB3 A;  3AQM A;  3AQN A;  1UEU A;  5J2F A;  5J2B A;  4I29 A;  4O67 A;  1VFG A;  8ICI A;  8ICE A;  4KLU A;  4R63 A;  4QZH A;  1HUO A;  3RJK A;  4FHV A;  4UB2 A;  4TUR A;  1R8B A;  3JPO A;  1UEV A;  2PFQ A;  1MIW A;  4LT6 A;  2ZH8 A;  4QZE A;  1ZQK A;  4Z6F A;  4XQ8 A;  9ICS A;  3ERC C;  3MDA A;  4EBK A;  4PH5 A;  3JPQ A;  8ICY A;  4YMO A;  4JWM A;  1NOM A;  4NKT A;  4ATB A;  4K4H A;  4NLK A;  4WC4 A;  3MGI A;  8ICL A;  5DBA A;  4RWP A;  3ER8 C;  4UBC A;  4KB6 A;  4PGY A;  4E7X A;  4WBZ A;  4I2A A;  7ICQ A;  5DDY A;  2BPG A;  7ICG A;  3V72 A;  4NXV A;  9ICO A;  3H38 A;  4I2I A;  5EOZ A;  9ICT A;  4WBY A;  3HJ1 A;  4EP7 A;  1UET A;  4RWQ A;  4I2D A;  2GAF D;  4M9J A;  4P4P A;  2DR9 A;  2DRB A;  3AU6 A;  4EEB A;  5J2G A;  4UB5 A;  3C2L A;  4KLD A;  5CJ7 A;  4FO1 A;  4YMN A;  1R8C A;  4R66 A;  1Q78 A;  2BCQ A;  5CFT A;  3ISB A;  4AT8 B;  5BOM A;  5J0P A;  4XQ7 A;  2DR5 A;  4Z6D A;  9ICL A;  4FH3 A;  3LQC B;  9ICA A;  9ICQ A;  1ZJM A;  4I2C A;  5J2A A;  9ICH A;  4M9G A;  4KLM A;  3JPR A;  4O6A A;  1ZQQ A;  4OAH A;  4KM5 A;  4X0A A;  2P66 A;  3UPQ A;  3H3A A;  8ICA A;  7ICN A;  1ZQC A;  1ZQT A;  9ICU A;  4FHP A;  8ICP A;  5IIK A;  2B56 A;  4NKU A;  1RPL A;  3UPS A;  4K8V A;  4IG8 A;  2VAN A;  4O5C A;  4QZ8 A;  3JCF A;  4I28 A;  4RQ2 A;  4UAW A;  7ICR A;  8ICX A;  4F5O A;  4X4N A;  3JPP A;  9ICB A;  5HHH A;  4FO6 A;  1ZQU A;  4P4O A;  4M9L A;  3WFP A;  4K99 A;  4TUP A;  4RWO A;  4TUQ A;  2IUB A;  4X4P A;  3OV7 A;  4KLT A;  3HIY A;  1ZQG A;  2BBJ A;  2ZH4 A;  5HRH A;  2IHM A;  4RQ0 A;  3NYB A;  5DEC A;  3H37 A;  8ICQ A;  4KLF A;  4I2J A;  5TZV A;  5BPC A;  4X4O A;  8ICO A;  7ICH A;  3K7D A;  4RT3 A;  4RT2 A;  5D46 A;  1ZQO A;  8ICG A;  4PHP A;  3OVA A;  3UXP A;  4O5E A;  3B0X A;  4S3N A;  4MFC A;  4K4I A;  5CB1 A;  5D62 A;  4RQ7 A;  4X4T A;  5BOL A;  2PFP A;  8ICR A;  4NXW A;  4M9N A;  4YN4 A;  4KLI A;  5HRL A;  1YLQ A;  4I2G A;  1ZQR A;  2DR8 A;  2ZH7 A;  2HN1 A;  2FMP A;  1TV9 A;  5HRI A;  4AT7 A;  4QZB A;  2FCL A;  4M0A A;  4WOY A;  1ZQH A;  4KLE A;  4DOA A;  3TFS A;  3MBY A;  4WQK A;  2BPC A;  4QZF A;  4PHE A;  4JWN A;  1ZJN A;  4QZ9 A;  2BPF A; 
#chains in the Genus database with same CATH homology
 4NXX A;  4EP7 A;  1UET A;  2GAF D;  4FHX A;  4OAF A;  2B4V A;  2DR9 A;  2DRB A;  3NKU A;  5CFS A;  4LEW A;  4AT7 B;  3OUY A;  2ZH2 A;  4FHW A;  4FO1 A;  4K9A A;  1R8C A;  1Q78 A;  4K97 A;  4JLZ A;  2DR7 A;  5CFT A;  4AT8 B;  4XJE A;  4FH5 A;  1F5A A;  2DR5 A;  2IHO A;  4FH3 A;  4UD5 A;  1R8A A;  3C66 A;  4LEZ A;  4AT8 A;  4MKP A;  4O6A A;  4X4Q A;  4OAH A;  4KM5 A;  4X4R A;  5B3P A;  3ER9 B;  3PHZ A;  1TFY A;  2ZH6 A;  4AT9 B;  4FHP A;  4HX0 A;  3OVB A;  4LEY A;  2B56 A;  4WQL A;  4X4S A;  4NKU A;  4K8V A;  4K96 A;  1Q79 A;  4O68 A;  5CFU A;  4OAG A;  4NXU A;  4AT9 A;  4UD4 A;  4LEV A;  1GPJ A;  3HJ4 A;  4X4N A;  2ZH1 A;  4K99 A;  4NXT A;  3MCR A;  4X4P A;  3OV7 A;  4N7R A;  3HIY A;  1FA0 A;  2ZH4 A;  2ZH9 A;  3EF2 A;  2EWR A;  4WH5 A;  4K98 A;  3NYB A;  4X4U A;  4E80 A;  2B51 A;  4M5D A;  2HHP A;  1UEU A;  5D61 A;  4O67 A;  5B3Q A;  4X4V A;  4X4O A;  4OAI Z;  1R89 A;  4E8F A;  3K7D A;  2Q66 A;  2ZH5 A;  1TFW A;  4FHV A;  3OVS A;  3OVA A;  2ZHA A;  4FHY A;  4K9B A;  1R8B A;  5D62 A;  1UEV A;  4ATB B;  2ZH3 A;  4LT6 A;  4X4T A;  2ZH8 A;  3OWG A;  2O1P A;  5CHE A;  4NXW A;  2ZHB A;  3ERC C;  2GA9 D;  4NKT A;  4ATB A;  2DR8 A;  2ZH7 A;  4AT7 A;  2DRA A;  2FCL A;  4JLX A;  3ER8 C;  4KB6 A;  4E7X A;  4WOY A;  5D63 A;  4NXV A;  4WQK A;  2DVI A;  3OUY B;  4O69 A;  3HJ1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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