4OAAA

Crystal structure of e. coli lactose permease g46w,g262w bound to sugar
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
407
structure length
391
Chain Sequence
LKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSDTWIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGIMFTINNQFVFWLGSGCALILAVLLFFAKTDAFSLKLALELFRQPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFWYVTTMGELLNASIMFFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCFKYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGFTLISVFTLSGPGPLSLLR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of sugar-bound LacY.
pubmed doi rcsb
molecule keywords Lactose/galactose transporter
molecule tags Transport protein
source organism Escherichia coli
total genus 121
structure length 391
sequence length 407
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-01-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4oaaA02
1.20.1250.20 Mainly Alpha Up-down Bundle Growth Hormone; Chain: A; MFS general substrate transporter like domains 4oaaA01
4GC0A 4LDSA 4J05A 4ZWCA 4D2CA 5A2OA 4TPHA 4YB9D 4UVMA 4APSA 4IKVA 4ZYRA 4YBQA 2Y5YA 4OH3A 4U4TA 2XUTA 2CFPA 5A2NA 4JR9A 5EQGA 4U4WA 4QIQA 4XNIA 3O7PA 4GBZA 3O7QA 1PV7A 4IKXA 4TPGA 4IKZA 4OAAA 4PYPA 5GXBA 4IU8A 4D2DA 2V8NA 5EQHA 4IKWA 3WDOA 4TPJA 4LEPA 5EQIA 4GBYA 1PV6A 4ZW9A 4Q65A 4D2BA 4JA3A 5D6KA 2CFQA 4U4VA 4XNJA 5D59A 4W6VA 1PW4A 5C65A 4JREA 4ZWBA 4IKYA 4IU9A 5D58A
chains in the Genus database with same CATH superfamily
4GC0A 1V7MV 2XQBA 2CFPA 3PIWA 4TPJA 1Y1VD 3HOXD 4IU8A 1LQSL 2H24A 3D48P 3DI3A 4O9HA 5D6KA 4A3ED 3L5XA 3D85C 4A3MD 1IJZA 3QAZA 1J7VL 3PO2D 5D72A 3BPOA 4NN6A 4DKEA 3OG6A 4YDYI 4A3LD 1AXIA 1HIKA 3QT2C 3QWRB 3VA2A 2JA7D 2E9WC 3G9VB 4IKVA 4ZF7A 1GNCA 2LMSA 5L6YC 4IKWA 2B8XA 4NEJA 4LRLA 5D70A 1ITMA 1BGCA 4NI7A 2B63D 1FYHA 3EJJA 5C3ED 2B8YA 4YB9D 4OH3A 3I4ND 3N0PA 2B90A 5D71A 5A2NA 1A22A 5FLMD 1Y14A 1FG9A 2Q14A 3Q1SI 2R93D 2D48A 1RHGA 1JLIA 1CD9A 3AYHA 5IYBD 1Y6NL 4U4VA 4XNJA 3HHCA 4YQXA 1RW5A 4DOHA 1QVNA 4UVMA 2Y5YA 3FKID 1EKUA 5C44D 4XNIA 3HOWD 1INRA 3UF2A 3DI2A 4NI9A 4GS7A 1M4RA 2GMFA 4NN7A 1M48A 4J4LC 3D87A 1PVHB 4GBZA 1PV7A 2V8NA 4PS4A 1D9CA 3PIVA 4GBYA 1BGEA 3NCEA 2ERJD 1N1FA 4A3GD 5IYDD 4W6VA 1CYLA 5C65A 2R92D 4APSA 4QIQA 2VUMD 4PYPA 1M49A 1CN4C 4X51A 4NN5A 4ZS7A 4ZW9A 2Z3RA 1GA3A 5E4EA 1IL6A 4BY1D 3BESL 3NCFA 4NKQC 5D58A 1I1RB 1WCMD 1BCNA 3BPNA 2C35A 4IKXA 4BY7D 4NEMA 2Q98A 5TS9A 1M4CA 1PGRA 4A3CD 3WCYI 1WU3I 2B8ZA 4BBRD 3B5KA 2CYKA 1AX8A 3H3VE 1Y1WD 4WRLB 2D9QA 1HUWA 3HOUD 3OG4A 3I4MD 1BP3A 4D2BA 2IL6A 3HOZD 1EVSA 3QB1A 2L3YA 4J05A 4ZWCA 3OQ3A 4DKFA 3PO3D 4RS1A 1Z92A 1Y6KL 5EQGA 3NCCA 4A3FD 3WDOA 5IP9D 5C7XA 4DKDA 2OQPA 3BPLA 3H0GD 4YUEC 5D28B 1CSGA 1F6FA 3HHRA 3NCBA 1PY2A 1V7NV 1IK0A 2B5IA 4BBSD 3S9DA 2L3OA 2O27A 2R7ZD 3L5WI 4ZYRA 1PW6A 4U4TA 2XUTA 4U4WA 4DKCA 1HZIA 2HYMB 2PSMA 3HOVD 1B5LA 5EQIA 1RFBA 4O6KA 4A3DD 1LKIA 5A2OA 4MHLA 1RCBA 1NBPA 4CNIC 3O7QA 5EQHA 1LK3A 1Z7CA 2JA8D 1Y6ML 3SE4B 1M4AA 2Z3QA 4JREA 4IKYA 1ETEA 5D22A 1ALUA 3EW3A 3UX9A 3UF5A 4EXPA 2Q7NB 1ITLA 1HIJA 4I77Z 1HWHA 4GRWA 4A93D 1HGUA 3MZGA 5KNHI 4LEPA 2O6IA 3HMXB 1KF9A 3DLQI 4A3ID 3INKC 4Q65A 1ILKA 2CFQA 3DUHC 1D9GA 4A3KD 2JA5D 3HOYD 5FHXA 3TGXB 1VLKA 4D2CA 3SE3B 3LB6A 1F45B 1AU1A 1HULA 2JA6D 1P9MB 1BGDA 3QB7A 4D2DA 1A7MA 3UEZE 1ITFA 3N06A 1CNT1 4JA3A 5C4XD 1M4BA 4LDSA 2ILKA 2B8UA 4YPGC 1IRLA 4TPHA 4YBQA 1M47A 4FA8E 3G6DA 1IARA 4TPGA 4IKZA 1BUYA 2KZ1A 1HWGA 1ITIA 4A3BD 3IRHA 1PV6A 5LQBA 3LB6B 5IP7D 1EMRA 2LAGA 1PW4A 2INTA 5IYCD 1EXZA 4ZWBA 4IU9A 2O26A 1YKBA 4EXNA 1BBNA 4JR9A 3O7PA 3DGCL 4OAAA 5GXBA 2B91A 4BXXD 1SCFA 4A3JD 1EERA 5D59A 5FUCA 4Z5RD 3NPZA
chains in the Genus database with same CATH topology
4GC0A 4LDSA 4J05A 4ZWCA 4D2CA 5A2OA 4TPHA 4YB9D 4UVMA 4APSA 4IKVA 4ZYRA 4YBQA 2Y5YA 4OH3A 4U4TA 2XUTA 2CFPA 5A2NA 4JR9A 5EQGA 4U4WA 4QIQA 4XNIA 3O7PA 4GBZA 3O7QA 1PV7A 4IKXA 4TPGA 4IKZA 4OAAA 4PYPA 5GXBA 4IU8A 4D2DA 2V8NA 5EQHA 4IKWA 3WDOA 4TPJA 4LEPA 5EQIA 4GBYA 1PV6A 4ZW9A 4Q65A 4D2BA 4JA3A 5D6KA 2CFQA 4U4VA 4XNJA 5D59A 4W6VA 1PW4A 5C65A 4JREA 4ZWBA 4IKYA 4IU9A 5D58A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4GC0 A;  4LDS A;  4J05 A;  4ZWC A;  4D2C A;  5A2O A;  4TPH A;  4YB9 D;  4UVM A;  4APS A;  4IKV A;  4ZYR A;  4YBQ A;  2Y5Y A;  4OH3 A;  4U4T A;  2XUT A;  2CFP A;  5A2N A;  4JR9 A;  5EQG A;  4U4W A;  4QIQ A;  4XNI A;  3O7P A;  4GBZ A;  3O7Q A;  1PV7 A;  4IKX A;  4TPG A;  4IKZ A;  4OAA A;  4PYP A;  5GXB A;  4IU8 A;  4D2D A;  2V8N A;  5EQH A;  4IKW A;  3WDO A;  4TPJ A;  4LEP A;  5EQI A;  4GBY A;  1PV6 A;  4ZW9 A;  4Q65 A;  4D2B A;  4JA3 A;  5D6K A;  2CFQ A;  4U4V A;  4XNJ A;  5D59 A;  4W6V A;  1PW4 A;  5C65 A;  4JRE A;  4ZWB A;  4IKY A;  4IU9 A;  5D58 A; 
#chains in the Genus database with same CATH topology
 4GC0 A;  1V7M V;  2XQB A;  2CFP A;  3PIW A;  4TPJ A;  1Y1V D;  3HOX D;  4IU8 A;  1LQS L;  2H24 A;  3D48 P;  3DI3 A;  4O9H A;  5D6K A;  4A3E D;  3L5X A;  3D85 C;  4A3M D;  1IJZ A;  3QAZ A;  1J7V L;  3PO2 D;  5D72 A;  3BPO A;  4NN6 A;  4DKE A;  3OG6 A;  4YDY I;  4A3L D;  1AXI A;  1HIK A;  3QT2 C;  3QWR B;  3VA2 A;  2JA7 D;  2E9W C;  3G9V B;  4IKV A;  4ZF7 A;  1GNC A;  2LMS A;  5L6Y C;  4IKW A;  2B8X A;  4NEJ A;  4LRL A;  5D70 A;  1ITM A;  1BGC A;  4NI7 A;  2B63 D;  1FYH A;  3EJJ A;  5C3E D;  2B8Y A;  4YB9 D;  4OH3 A;  3I4N D;  3N0P A;  2B90 A;  5D71 A;  5A2N A;  1A22 A;  5FLM D;  1Y14 A;  1FG9 A;  2Q14 A;  3Q1S I;  2R93 D;  2D48 A;  1RHG A;  1JLI A;  1CD9 A;  3AYH A;  5IYB D;  1Y6N L;  4U4V A;  4XNJ A;  3HHC A;  4YQX A;  1RW5 A;  4DOH A;  1QVN A;  4UVM A;  2Y5Y A;  3FKI D;  1EKU A;  5C44 D;  4XNI A;  3HOW D;  1INR A;  3UF2 A;  3DI2 A;  4NI9 A;  4GS7 A;  1M4R A;  2GMF A;  4NN7 A;  1M48 A;  4J4L C;  3D87 A;  1PVH B;  4GBZ A;  1PV7 A;  2V8N A;  4PS4 A;  1D9C A;  3PIV A;  4GBY A;  1BGE A;  3NCE A;  2ERJ D;  1N1F A;  4A3G D;  5IYD D;  4W6V A;  1CYL A;  5C65 A;  2R92 D;  4APS A;  4QIQ A;  2VUM D;  4PYP A;  1M49 A;  1CN4 C;  4X51 A;  4NN5 A;  4ZS7 A;  4ZW9 A;  2Z3R A;  1GA3 A;  5E4E A;  1IL6 A;  4BY1 D;  3BES L;  3NCF A;  4NKQ C;  5D58 A;  1I1R B;  1WCM D;  1BCN A;  3BPN A;  2C35 A;  4IKX A;  4BY7 D;  4NEM A;  2Q98 A;  5TS9 A;  1M4C A;  1PGR A;  4A3C D;  3WCY I;  1WU3 I;  2B8Z A;  4BBR D;  3B5K A;  2CYK A;  1AX8 A;  3H3V E;  1Y1W D;  4WRL B;  2D9Q A;  1HUW A;  3HOU D;  3OG4 A;  3I4M D;  1BP3 A;  4D2B A;  2IL6 A;  3HOZ D;  1EVS A;  3QB1 A;  2L3Y A;  4J05 A;  4ZWC A;  3OQ3 A;  4DKF A;  3PO3 D;  4RS1 A;  1Z92 A;  1Y6K L;  5EQG A;  3NCC A;  4A3F D;  3WDO A;  5IP9 D;  5C7X A;  4DKD A;  2OQP A;  3BPL A;  3H0G D;  4YUE C;  5D28 B;  1CSG A;  1F6F A;  3HHR A;  3NCB A;  1PY2 A;  1V7N V;  1IK0 A;  2B5I A;  4BBS D;  3S9D A;  2L3O A;  2O27 A;  2R7Z D;  3L5W I;  4ZYR A;  1PW6 A;  4U4T A;  2XUT A;  4U4W A;  4DKC A;  1HZI A;  2HYM B;  2PSM A;  3HOV D;  1B5L A;  5EQI A;  1RFB A;  4O6K A;  4A3D D;  1LKI A;  5A2O A;  4MHL A;  1RCB A;  1NBP A;  4CNI C;  3O7Q A;  5EQH A;  1LK3 A;  1Z7C A;  2JA8 D;  1Y6M L;  3SE4 B;  1M4A A;  2Z3Q A;  4JRE A;  4IKY A;  1ETE A;  5D22 A;  1ALU A;  3EW3 A;  3UX9 A;  3UF5 A;  4EXP A;  2Q7N B;  1ITL A;  1HIJ A;  4I77 Z;  1HWH A;  4GRW A;  4A93 D;  1HGU A;  3MZG A;  5KNH I;  4LEP A;  2O6I A;  3HMX B;  1KF9 A;  3DLQ I;  4A3I D;  3INK C;  4Q65 A;  1ILK A;  2CFQ A;  3DUH C;  1D9G A;  4A3K D;  2JA5 D;  3HOY D;  5FHX A;  3TGX B;  1VLK A;  4D2C A;  3SE3 B;  3LB6 A;  1F45 B;  1AU1 A;  1HUL A;  2JA6 D;  1P9M B;  1BGD A;  3QB7 A;  4D2D A;  1A7M A;  3UEZ E;  1ITF A;  3N06 A;  1CNT 1;  4JA3 A;  5C4X D;  1M4B A;  4LDS A;  2ILK A;  2B8U A;  4YPG C;  1IRL A;  4TPH A;  4YBQ A;  1M47 A;  4FA8 E;  3G6D A;  1IAR A;  4TPG A;  4IKZ A;  1BUY A;  2KZ1 A;  1HWG A;  1ITI A;  4A3B D;  3IRH A;  1PV6 A;  5LQB A;  3LB6 B;  5IP7 D;  1EMR A;  2LAG A;  1PW4 A;  2INT A;  5IYC D;  1EXZ A;  4ZWB A;  4IU9 A;  2O26 A;  1YKB A;  4EXN A;  1BBN A;  4JR9 A;  3O7P A;  3DGC L;  4OAA A;  5GXB A;  2B91 A;  4BXX D;  1SCF A;  4A3J D;  1EER A;  5D59 A;  5FUC A;  4Z5R D;  3NPZ A; 
#chains in the Genus database with same CATH homology
 4GC0 A;  4LDS A;  4J05 A;  4ZWC A;  4D2C A;  5A2O A;  4TPH A;  4YB9 D;  4UVM A;  4APS A;  4IKV A;  4ZYR A;  4YBQ A;  2Y5Y A;  4OH3 A;  4U4T A;  2XUT A;  2CFP A;  5A2N A;  4JR9 A;  5EQG A;  4U4W A;  4QIQ A;  4XNI A;  3O7P A;  4GBZ A;  3O7Q A;  1PV7 A;  4IKX A;  4TPG A;  4IKZ A;  4OAA A;  4PYP A;  5GXB A;  4IU8 A;  4D2D A;  2V8N A;  5EQH A;  4IKW A;  3WDO A;  4TPJ A;  4LEP A;  5EQI A;  4GBY A;  1PV6 A;  4ZW9 A;  4Q65 A;  4D2B A;  4JA3 A;  5D6K A;  2CFQ A;  4U4V A;  4XNJ A;  5D59 A;  4W6V A;  1PW4 A;  5C65 A;  4JRE A;  4ZWB A;  4IKY A;  4IU9 A;  5D58 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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