4OKGA

Lpxc from p.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiperazin-1-yl)methyl]-3-pyridyl]ethynyl]phenyl]pyridine-3-carbohydroxamic acid
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
299
structure length
299
Chain Sequence
MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Overexpression of Pseudomonas aeruginosa LpxC in the Presence of an Inhibitor in an acrB Deletion Escherichia coli strain for Structural Studies
rcsb
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
molecule tags Hydrolase/hydrolase inhibitor
source organism Pseudomonas aeruginosa
total genus 88
structure length 299
sequence length 299
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4okgA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4okgA02
4LCFA 4OZEA 2IESA 3P3EA 2GO4A 4IS9A 2GO3A 4ISAA 4LCGA 5DRQA 4MQYA 4FW3A 3PS1A 3P3CA 1XXEA 4MDTA 4U3DA 4FW7A 4U3BA 5DRPA 1YHCA 4LCHA 2J65A 3U1YA 4FW6A 3PS3A 5DRRA 3NZKA 2IERA 1YH8A 1P42A 3P3GA 4J3DA 4FW4A 3PS2A 2VESA 5DROA 2O3ZA 3UHMA 2JT2A 4OKGA 3P76A 4FW5A
chains in the Genus database with same CATH superfamily
1OYPA 4LFCI 3ZZ0A 4PRXA 4AIDA 4X62I 5C0XD 4JI2I 2HKEA 4NXMI 1MU5A 4B3RI 1R6MA 1WUUA 2ZM6I 2PO2A 1KVKA 4DR4E 2BM1A 2J7KA 1XHKA 4HACB 4JI1E 2DEJA 4B3TI 2J65A 3J7AM 1N36I 5C0XE 1FWLA 2R3VA 1FJGE 5LL6R 2C38A 1A6FA 3CDJA 4LFBI 1B62A 4URLA 1IBKE 2UUBE 3GLLA 2A2DA 2PNZB 3J7AG 4IFDD 2F4VE 4LF7I 4JI6E 4KHPE 2VQFI 1IBLI 4B3ME 2PO1A 4U3BA 1USVA 2PO2B 1FNMA 3PS3A 1EA6A 1FWKA 2E1RA 2E5LI 4IFDE 2VESA 2GQ0A 2CZ9A 4GKKE 4JG4A 5JEAC 3P76A 3OTOE 4QNJA 4OZEA 4JI7I 4DR1I 1Z5BA 1Z59A 4JI4I 4IZJA 5LMUI 2UXBI 4Z7YA 4N3OA 5DRQA 1I94I 1PVGA 1XXEA 3M6AA 3HKMA 4U3DA 4LFAE 3WU6A 2UU9I 3GCMA 4IFDB 3CWVA 2UXCE 3KRNA 2JEBA 3PYGA 2PO1B 1J5EI 4M1KA 4JI3I 1XMOE 2Q2EB 1HNXE 4LF8E 3LPSA 1ZM3A 3V2UC 2VQEI 4UTGA 2UUAE 2HHHE 3DD6A 3K85A 1ZXNA 3P3EA 2GO3A 3ZM7A 3P3CA 4DV0E 5GMEA 4OO1C 4DPTA 1HR0E 1DARA 1UDSA 2ZBKB 3D4JA 1IBME 1N34E 4WUBA 2UUCE 2NN6D 2HK2A 3ZKDA 4DR2I 4DV2I 2X36A 4GKJI 1RREA 4DV3E 4X66E 3J80C 4BA1A 4K0KI 4JI8I 1USUA 4MYUA 4YHHI 4JYAI 5EKWA 2PNMA 2NN6E 2BA1G 2UXDI 4FN5A 5K36A 1Y6ZA 4ED4A 1OJ4A 3H1CA 1MG7A 1XNQE 1ELOA 4PRVA 5DRRA 1YH8A 2PO0A 4JI5E 3HULA 3T1YI 1HNZE 4X64I 4DUZE 4JI0E 2NN6B 2PNLA 4BA1B 3Q1QA 4DV4E 4QNKA 2C37A 2WNRA 5FLXC 1N32E 4LF6E 4JV5E 5C0XC 4AQYE 5K36B 4FW6A 1E3HA 1PIEA 2JE6A 4DV5E 3P3GA 5LMNE 2V8PA 4DR4I 4OX9E 1VI7A 3V5RA 1KTVA 2CGEA 4JI1I 4NBQA 1Y4UA 2PO0B 5L3JA 4USMA 4UT4A 1FJGI 3J80Q 4LPFA 4OO1F 4DV7E 4ZVIA 1IBKI 1KKHA 3WU4A 2UUBI 3QT6A 2WNRB 3U1YA 3M7NG 1S16A 3WU3A 3K1JA 4LOMA 2F4VI 4IFDC 4X65E 1H74A 4DUYE 2R42A 4JI6I 4KHPI 1B63A 5BR8E 4B3MI 3J81C 2IOQA 2JE6B 4KQVA 4DV1E 2IOPA 4LCFA 4IZJD 2C38B 4Z7CA 1FI4A 2XEXA 4GKKI 2WW4A 3OTOI 2BA1D 2BA0D 4DPYA 2AJ4A 5JEAA 4DR6E 3NZKA 5FLXQ 1N33E 1NHIA 4LF5E 2JT2A 4LFAI 4DR7I 3L7ZA 3PYEA 1BKNA 4LF9E 1Y5YA 4DXLA 2AE8A 4B3SE 4HY1A 1MX0A 2UXCI 2LJPA 1UDOA 1EI1A 2C39A 4FWHA 1NHHA 1OYRA 1UDNA 4HYMA 1XMOI 1HNXI 4LF8I 4DR3E 4YY3E 5GMDA 2WP8A 1XMQE 2UUAI 4NXNE 4DPXA 2HHHI 5C0XF 5IT9C 4IZJB 3F0NA 3ZZTA 5ELWA 4LF4E 1D6TA 1Z0GA 2IERA 2EFGA 5FWKA 1Z0TA 4DV0I 1HR0I 2NPFA 5JEAB 1ZM4A 2Z5EA 1N34I 1KIJA 4OO1A 2JEBB 2F1DA 2UUCI 4USKA 4XTJA 3L7ZB 3J81Q 4IS9A 4EMDA 5K36D 2BV3A 4X66I 4DV3I 2BA0G 4DV6E 4DR5E 2X7IA 4FWGA 3PYFA 2C39B 3T1HE 3H4LA 1H73A 1HNWE 5DRPA 4IFDF 3Q6MA 1Z0WA 1Z0CA 2WP8B 4FWDA 2BM0A 4J3DA 3GONA 4DU7A 3HJCA 2Z5CA 3M7ND 5K36E 4WUCA 4WUDA 5IWAE 1XNQI 1Y60A 4MU3A 2CG9A 1PKPA 4JI5I 4HACA 4MU0A 3CDIA 1N0VC 1XNRE 4AM3A 3P06A 4LCGA 4OO1B 1HNZI 4HXZA 2VF3A 1ZXMA 4DUZI 3JAMC 4JI0I 3U1KA 4P52A 3LNUA 2O1WA 1QZRA 4DV4I 1Z0BA 4LFCE 1P42A 2BR2A 4I3HA 3PS2A 4X62E 4JI2E 1N32I 4BA2A 5IT9Q 4NXME 4B3RE 4LF6I 2ZM6E 2PNZA 5DNLA 4JV5I 4MU4A 2O1VA 1RR9A 4AQYI 2HK3A 3LTOA 2Z5CB 1H72C 1ZM9A 4DV5I 2IESA 5LMNI 4OX9I 4B3TE 1N36E 5C0XA 1FKAE 1Z0VA 4FW3A 4MQYA 1N0UA 2HFUA 5EL9A 3QT8A 4LFBE 2C37B 4DV7I 4LF7E 2JEAA 2BR2B 2NN6F 2DEIA 4IZKA 2VQFE 1IBLE 4BA2B 2GS8A 3PRYA 4X65I 4DUYI 5BR8I 1VISA 4IFDA 2E5LE 2A2CA 4DV1I 4GQUA 1OYSA 1Z0EA 4MYTA 4FW9A 4MU1A 5DNXA 5JEAD 5A2QC 4R1FA 5C0XB 5K36F 3ZKBA 4JI7E 1U2RA 3JAMQ 4DR1E 2O3ZA 1UEKA 5LMUE 4JI4E 2UXBE 1I94E 1NHJA 1UDQA 2V34A 3ZZUA 5JEAE 2O1TA 4DR6I 1H7SA 3M85D 1N33I 1RHYA 4LF5I 2UU9E 3B82A 2GO4A 3B8HA 2JEAB 1K47A 4IZKB 3GMEA 1E3PA 4LF9I 1J5EE 4JI3E 4DR7E 4B3SI 3B78A 1R6LA 1ZM2A 2VQEE 1H7UA 2V2QA 1Z5CA 4DR3I 4YY3I 4FW4A 1S4EA 1XMQI 2V2VA 4OKGA 4NXNI 4DU8A 4OO1D 1IBMI 4LF4I 3QT7A 4AIMA 2NN6C 3PYDA 2HKJA 4DPUA 3B4TA 3PS1A 4PU9A 4DV2E 2Z5BA 4DR2E 4GKJE 2CVEA 2V2ZA 3Q6NA 4OO1E 1Z5AA 2ZITA 1YHCA 4P7AA 4LCHA 4JI8E 4K0KE 3QT5A 4YHHE 5K36C 4JYAE 4DV6I 2NN6A 5DROA 4DR5I 5A2QQ 3T1HI 2UXDE 1HNWI 3M85G 1HK7A 4DPWA 4ISAA 5IWAI 4MDTA 4FW7A 3T1YE 4RPFA 2OI2A 4X64E 1XNRI 2Z5BB 1Y4SA 5JEAF 2O1UA 1NZ0A 3WU5A 3UHMA 3K17A 4FW5A 2HFSA
chains in the Genus database with same CATH topology
4LCFA 4OZEA 2IESA 3P3EA 2GO4A 4IS9A 2GO3A 4ISAA 4LCGA 5DRQA 4MQYA 4FW3A 3PS1A 3P3CA 1XXEA 4MDTA 4U3DA 4FW7A 4U3BA 5DRPA 1YHCA 4LCHA 2J65A 3U1YA 4FW6A 3PS3A 5DRRA 3NZKA 2IERA 1YH8A 1P42A 3P3GA 4J3DA 4FW4A 3PS2A 2VESA 5DROA 2O3ZA 3UHMA 2JT2A 4OKGA 3P76A 4FW5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LCF A;  4OZE A;  2IES A;  3P3E A;  2GO4 A;  4IS9 A;  2GO3 A;  4ISA A;  4LCG A;  5DRQ A;  4MQY A;  4FW3 A;  3PS1 A;  3P3C A;  1XXE A;  4MDT A;  4U3D A;  4FW7 A;  4U3B A;  5DRP A;  1YHC A;  4LCH A;  2J65 A;  3U1Y A;  4FW6 A;  3PS3 A;  5DRR A;  3NZK A;  2IER A;  1YH8 A;  1P42 A;  3P3G A;  4J3D A;  4FW4 A;  3PS2 A;  2VES A;  5DRO A;  2O3Z A;  3UHM A;  2JT2 A;  4OKG A;  3P76 A;  4FW5 A; 
#chains in the Genus database with same CATH topology
 1OYP A;  4LFC I;  3ZZ0 A;  4PRX A;  4AID A;  4X62 I;  5C0X D;  4JI2 I;  2HKE A;  4NXM I;  1MU5 A;  4B3R I;  1R6M A;  1WUU A;  2ZM6 I;  2PO2 A;  1KVK A;  4DR4 E;  2BM1 A;  2J7K A;  1XHK A;  4HAC B;  4JI1 E;  2DEJ A;  4B3T I;  2J65 A;  3J7A M;  1N36 I;  5C0X E;  1FWL A;  2R3V A;  1FJG E;  5LL6 R;  2C38 A;  1A6F A;  3CDJ A;  4LFB I;  1B62 A;  4URL A;  1IBK E;  2UUB E;  3GLL A;  2A2D A;  2PNZ B;  3J7A G;  4IFD D;  2F4V E;  4LF7 I;  4JI6 E;  4KHP E;  2VQF I;  1IBL I;  4B3M E;  2PO1 A;  4U3B A;  1USV A;  2PO2 B;  1FNM A;  3PS3 A;  1EA6 A;  1FWK A;  2E1R A;  2E5L I;  4IFD E;  2VES A;  2GQ0 A;  2CZ9 A;  4GKK E;  4JG4 A;  5JEA C;  3P76 A;  3OTO E;  4QNJ A;  4OZE A;  4JI7 I;  4DR1 I;  1Z5B A;  1Z59 A;  4JI4 I;  4IZJ A;  5LMU I;  2UXB I;  4Z7Y A;  4N3O A;  5DRQ A;  1I94 I;  1PVG A;  1XXE A;  3M6A A;  3HKM A;  4U3D A;  4LFA E;  3WU6 A;  2UU9 I;  3GCM A;  4IFD B;  3CWV A;  2UXC E;  3KRN A;  2JEB A;  3PYG A;  2PO1 B;  1J5E I;  4M1K A;  4JI3 I;  1XMO E;  2Q2E B;  1HNX E;  4LF8 E;  3LPS A;  1ZM3 A;  3V2U C;  2VQE I;  4UTG A;  2UUA E;  2HHH E;  3DD6 A;  3K85 A;  1ZXN A;  3P3E A;  2GO3 A;  3ZM7 A;  3P3C A;  4DV0 E;  5GME A;  4OO1 C;  4DPT A;  1HR0 E;  1DAR A;  1UDS A;  2ZBK B;  3D4J A;  1IBM E;  1N34 E;  4WUB A;  2UUC E;  2NN6 D;  2HK2 A;  3ZKD A;  4DR2 I;  4DV2 I;  2X36 A;  4GKJ I;  1RRE A;  4DV3 E;  4X66 E;  3J80 C;  4BA1 A;  4K0K I;  4JI8 I;  1USU A;  4MYU A;  4YHH I;  4JYA I;  5EKW A;  2PNM A;  2NN6 E;  2BA1 G;  2UXD I;  4FN5 A;  5K36 A;  1Y6Z A;  4ED4 A;  1OJ4 A;  3H1C A;  1MG7 A;  1XNQ E;  1ELO A;  4PRV A;  5DRR A;  1YH8 A;  2PO0 A;  4JI5 E;  3HUL A;  3T1Y I;  1HNZ E;  4X64 I;  4DUZ E;  4JI0 E;  2NN6 B;  2PNL A;  4BA1 B;  3Q1Q A;  4DV4 E;  4QNK A;  2C37 A;  2WNR A;  5FLX C;  1N32 E;  4LF6 E;  4JV5 E;  5C0X C;  4AQY E;  5K36 B;  4FW6 A;  1E3H A;  1PIE A;  2JE6 A;  4DV5 E;  3P3G A;  5LMN E;  2V8P A;  4DR4 I;  4OX9 E;  1VI7 A;  3V5R A;  1KTV A;  2CGE A;  4JI1 I;  4NBQ A;  1Y4U A;  2PO0 B;  5L3J A;  4USM A;  4UT4 A;  1FJG I;  3J80 Q;  4LPF A;  4OO1 F;  4DV7 E;  4ZVI A;  1IBK I;  1KKH A;  3WU4 A;  2UUB I;  3QT6 A;  2WNR B;  3U1Y A;  3M7N G;  1S16 A;  3WU3 A;  3K1J A;  4LOM A;  2F4V I;  4IFD C;  4X65 E;  1H74 A;  4DUY E;  2R42 A;  4JI6 I;  4KHP I;  1B63 A;  5BR8 E;  4B3M I;  3J81 C;  2IOQ A;  2JE6 B;  4KQV A;  4DV1 E;  2IOP A;  4LCF A;  4IZJ D;  2C38 B;  4Z7C A;  1FI4 A;  2XEX A;  4GKK I;  2WW4 A;  3OTO I;  2BA1 D;  2BA0 D;  4DPY A;  2AJ4 A;  5JEA A;  4DR6 E;  3NZK A;  5FLX Q;  1N33 E;  1NHI A;  4LF5 E;  2JT2 A;  4LFA I;  4DR7 I;  3L7Z A;  3PYE A;  1BKN A;  4LF9 E;  1Y5Y A;  4DXL A;  2AE8 A;  4B3S E;  4HY1 A;  1MX0 A;  2UXC I;  2LJP A;  1UDO A;  1EI1 A;  2C39 A;  4FWH A;  1NHH A;  1OYR A;  1UDN A;  4HYM A;  1XMO I;  1HNX I;  4LF8 I;  4DR3 E;  4YY3 E;  5GMD A;  2WP8 A;  1XMQ E;  2UUA I;  4NXN E;  4DPX A;  2HHH I;  5C0X F;  5IT9 C;  4IZJ B;  3F0N A;  3ZZT A;  5ELW A;  4LF4 E;  1D6T A;  1Z0G A;  2IER A;  2EFG A;  5FWK A;  1Z0T A;  4DV0 I;  1HR0 I;  2NPF A;  5JEA B;  1ZM4 A;  2Z5E A;  1N34 I;  1KIJ A;  4OO1 A;  2JEB B;  2F1D A;  2UUC I;  4USK A;  4XTJ A;  3L7Z B;  3J81 Q;  4IS9 A;  4EMD A;  5K36 D;  2BV3 A;  4X66 I;  4DV3 I;  2BA0 G;  4DV6 E;  4DR5 E;  2X7I A;  4FWG A;  3PYF A;  2C39 B;  3T1H E;  3H4L A;  1H73 A;  1HNW E;  5DRP A;  4IFD F;  3Q6M A;  1Z0W A;  1Z0C A;  2WP8 B;  4FWD A;  2BM0 A;  4J3D A;  3GON A;  4DU7 A;  3HJC A;  2Z5C A;  3M7N D;  5K36 E;  4WUC A;  4WUD A;  5IWA E;  1XNQ I;  1Y60 A;  4MU3 A;  2CG9 A;  1PKP A;  4JI5 I;  4HAC A;  4MU0 A;  3CDI A;  1N0V C;  1XNR E;  4AM3 A;  3P06 A;  4LCG A;  4OO1 B;  1HNZ I;  4HXZ A;  2VF3 A;  1ZXM A;  4DUZ I;  3JAM C;  4JI0 I;  3U1K A;  4P52 A;  3LNU A;  2O1W A;  1QZR A;  4DV4 I;  1Z0B A;  4LFC E;  1P42 A;  2BR2 A;  4I3H A;  3PS2 A;  4X62 E;  4JI2 E;  1N32 I;  4BA2 A;  5IT9 Q;  4NXM E;  4B3R E;  4LF6 I;  2ZM6 E;  2PNZ A;  5DNL A;  4JV5 I;  4MU4 A;  2O1V A;  1RR9 A;  4AQY I;  2HK3 A;  3LTO A;  2Z5C B;  1H72 C;  1ZM9 A;  4DV5 I;  2IES A;  5LMN I;  4OX9 I;  4B3T E;  1N36 E;  5C0X A;  1FKA E;  1Z0V A;  4FW3 A;  4MQY A;  1N0U A;  2HFU A;  5EL9 A;  3QT8 A;  4LFB E;  2C37 B;  4DV7 I;  4LF7 E;  2JEA A;  2BR2 B;  2NN6 F;  2DEI A;  4IZK A;  2VQF E;  1IBL E;  4BA2 B;  2GS8 A;  3PRY A;  4X65 I;  4DUY I;  5BR8 I;  1VIS A;  4IFD A;  2E5L E;  2A2C A;  4DV1 I;  4GQU A;  1OYS A;  1Z0E A;  4MYT A;  4FW9 A;  4MU1 A;  5DNX A;  5JEA D;  5A2Q C;  4R1F A;  5C0X B;  5K36 F;  3ZKB A;  4JI7 E;  1U2R A;  3JAM Q;  4DR1 E;  2O3Z A;  1UEK A;  5LMU E;  4JI4 E;  2UXB E;  1I94 E;  1NHJ A;  1UDQ A;  2V34 A;  3ZZU A;  5JEA E;  2O1T A;  4DR6 I;  1H7S A;  3M85 D;  1N33 I;  1RHY A;  4LF5 I;  2UU9 E;  3B82 A;  2GO4 A;  3B8H A;  2JEA B;  1K47 A;  4IZK B;  3GME A;  1E3P A;  4LF9 I;  1J5E E;  4JI3 E;  4DR7 E;  4B3S I;  3B78 A;  1R6L A;  1ZM2 A;  2VQE E;  1H7U A;  2V2Q A;  1Z5C A;  4DR3 I;  4YY3 I;  4FW4 A;  1S4E A;  1XMQ I;  2V2V A;  4OKG A;  4NXN I;  4DU8 A;  4OO1 D;  1IBM I;  4LF4 I;  3QT7 A;  4AIM A;  2NN6 C;  3PYD A;  2HKJ A;  4DPU A;  3B4T A;  3PS1 A;  4PU9 A;  4DV2 E;  2Z5B A;  4DR2 E;  4GKJ E;  2CVE A;  2V2Z A;  3Q6N A;  4OO1 E;  1Z5A A;  2ZIT A;  1YHC A;  4P7A A;  4LCH A;  4JI8 E;  4K0K E;  3QT5 A;  4YHH E;  5K36 C;  4JYA E;  4DV6 I;  2NN6 A;  5DRO A;  4DR5 I;  5A2Q Q;  3T1H I;  2UXD E;  1HNW I;  3M85 G;  1HK7 A;  4DPW A;  4ISA A;  5IWA I;  4MDT A;  4FW7 A;  3T1Y E;  4RPF A;  2OI2 A;  4X64 E;  1XNR I;  2Z5B B;  1Y4S A;  5JEA F;  2O1U A;  1NZ0 A;  3WU5 A;  3UHM A;  3K17 A;  4FW5 A;  2HFS A; 
#chains in the Genus database with same CATH homology
 4LCF A;  4OZE A;  2IES A;  3P3E A;  2GO4 A;  4IS9 A;  2GO3 A;  4ISA A;  4LCG A;  5DRQ A;  4MQY A;  4FW3 A;  3PS1 A;  3P3C A;  1XXE A;  4MDT A;  4U3D A;  4FW7 A;  4U3B A;  5DRP A;  1YHC A;  4LCH A;  2J65 A;  3U1Y A;  4FW6 A;  3PS3 A;  5DRR A;  3NZK A;  2IER A;  1YH8 A;  1P42 A;  3P3G A;  4J3D A;  4FW4 A;  3PS2 A;  2VES A;  5DRO A;  2O3Z A;  3UHM A;  2JT2 A;  4OKG A;  3P76 A;  4FW5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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