4OKGA

Lpxc from p.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiperazin-1-yl)methyl]-3-pyridyl]ethynyl]phenyl]pyridine-3-carbohydroxamic acid
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
299
structure length
299
Chain Sequence
MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Overexpression of Pseudomonas aeruginosa LpxC in the Presence of an Inhibitor in an acrB Deletion Escherichia coli strain for Structural Studies
rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 88
structure length 299
sequence length 299
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4okgA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4okgA02
2GO3A 4MDTA 4U3BA 4FW5A 2IERA 4FW4A 2IESA 4FW7A 3P3EA 3P3CA 4OZEA 2GO4A 4FW6A 3PS1A 1YH8A 3NZKA 2JT2A 3PS2A 4OKGA 2VESA 4U3DA 1YHCA 1XXEA 4ISAA 4LCHA 3P76A 3P3GA 3UHMA 4FW3A 4J3DA 4IS9A 4MQYA 4LCFA 5DROA 5DRPA 5DRRA 4LCGA 1P42A 2J65A 2O3ZA 3U1YA 5DRQA 3PS3A
chains in the Genus database with same CATH superfamily
3CDIA 1XMQE 1UDNA 4JI2I 5DNXA 4X66I 3M7NG 4USMA 4DR3I 4LFBI 1OYRA 1Z5BA 1H74A 3P3EA 4WUCA 3F0NA 4JG4A 4NXME 4LF6I 4R1FA 3K85A 2UXCI 4AM3A 1HNXI 2PO1A 2ZM6E 4IFDE 5A2QQ 2WP8A 2O1TA 5BR8I 4LF8E 1EA6A 2F4VE 4IZJB 4DUZE 1Z59A 2HK2A 1NHJA 4DV0E 4AIMA 2GQ0A 4X64I 1N36I 2PO2A 1N0UA 1HR0I 1E3PA 4B3ME 1A6FA 2UXBE 2NN6C 2NN6F 2UUBI 4JI3I 3T1YE 4DV1I 1N0VC 2UUAE 3J80Q 1H73A 4XTJA 4MU0A 4HACB 2C37B 4NXNE 4JI0E 5JEAC 4LFAE 4IZKB 4PRVA 4LPFA 4ZVIA 5C0XD 2IERA 1N32E 3QT6A 3ZZUA 4FWGA 3ZZ0A 4BA1B 1Y60A 4GKJE 3PYDA 4Z7CA 2VESA 5K36C 2PNLA 4NBQA 1XMOE 1R6MA 4B3TI 4DXLA 1HNWE 2JE6B 4LF5I 4B3RI 2V2QA 4URLA 4BA2A 1FJGI 3LNUA 5DRRA 2J65A 1H7SA 1HNXE 4DU7A 4DR6I 5ELWA 4FWHA 5LMUI 4GKKE 1ZM9A 1N33E 3OTOE 2C39A 2F4VI 2PO2B 3J80C 3J7AG 3HKMA 2VQEI 2XEXA 3QT8A 4IZJD 4X64E 2LJPA 1N36E 4J3DA 5JEAA 4LCFA 2AE8A 4YY3I 5GMEA 2HFUA 5DRQA 1J5EE 4DR5E 2NN6A 2PNMA 1XHKA 3ZKDA 1Z5AA 1FWKA 4HXZA 4BA1A 5A2QC 4X62E 4MU4A 3B78A 4OZEA 3K17A 4DPYA 3HJCA 4IFDC 4LF9E 4IZKA 3Q6NA 4DR2E 4IFDD 3PRYA 2NPFA 5C0XA 3PYGA 4DPWA 3T1HE 1IBMI 4X65E 2V8PA 5DRPA 1ELOA 2CG9A 3U1YA 1HNWI 5C0XE 3M7ND 4OO1B 2V34A 3GONA 4MYTA 4KHPE 3WU5A 1H7UA 4DV3E 3HULA 4FW4A 1U2RA 4JI5E 3KRNA 3ZKBA 4B3SI 4DV7I 1N34E 3WU6A 3OTOI 1E3HA 1Z0GA 2UXDI 4YHHE 5K36F 1VISA 4NXMI 2HFSA 2VQFE 2O1UA 2PO1B 5DROA 1VI7A 2WNRA 2Z5CA 4DV6I 1FWLA 1HNZE 3J7AM 2X36A 4X66E 2PO0B 2O1VA 3Q1QA 1BKNA 5K36E 1USUA 1XNQE 4FW7A 4LF6E 4JV5E 4LOMA 3P3CA 4DPTA 3L7ZB 2JEBB 4M1KA 2AJ4A 4LF4I 1IBKE 1Z0WA 4X62I 2UU9I 4DUYI 1XNRI 3H1CA 1FKAE 4LF7I 1KIJA 2ZM6I 2BA1D 2CZ9A 4DV5I 1WUUA 1HR0E 1IBLI 4ED4A 4JI3E 4JI6I 4JI7I 4HYMA 1S4EA 4JYAE 2BR2B 3M85D 4USKA 4X65I 4DR4I 2BA0D 2O1WA 4IFDB 5FLXQ 2HKEA 4MYUA 2JEAB 2C38B 2C38A 2JEAA 3PS1A 3NZKA 2IOQA 2UUBE 4JI5I 4OO1D 1Y5YA 4OO1E 5JEAF 3P06A 1PIEA 1Y4SA 4K0KI 2Q2EB 2NN6E 3B82A 2UXCE 1UDOA 4KQVA 1K47A 4LCGA 1PKPA 3QT5A 2R42A 3PS3A 1ZXMA 4IZJA 1RREA 4MU1A 1Z0CA 4U3BA 4OO1A 1FJGE 3JAMC 1OYPA 3LPSA 4GKJI 4DUZI 3B8HA 4OX9E 2BA1G 5LMNE 4B3TE 4UT4A 2GO4A 5C0XF 1N33I 1MX0A 2PO0A 2Z5EA 4JV5I 2UUCI 4MU3A 4PU9A 3WU4A 2ZITA 4HACA 4IS9A 1ZM3A 1DARA 4WUDA 2UUAI 1FNMA 2JEBA 5EKWA 5IWAE 4JI4E 5K36D 1ZXNA 4JI2E 3CWVA 3V2UC 4YY3E 1UDSA 1UDQA 4JI0I 1J5EI 2EFGA 4JI8I 4UTGA 4JI1E 2A2CA 3U1KA 2Z5BB 1OYSA 2BR2A 5JEAB 4DV2E 1N32I 5K36A 4OKGA 4U3DA 2WNRB 2Z5CB 1Z5CA 1USVA 4ISAA 1XMOI 2V2ZA 2J7KA 4I3HA 2WW4A 4LF9I 2HHHI 1I94E 4K0KE 4DR1I 1NZ0A 2Z5BA 1IBME 4MDTA 4DV4E 4AQYI 1Y4UA 2E1RA 2ZBKB 4FWDA 1KVKA 2E5LE 3GCMA 5GMDA 4FW6A 4GKKI 1RHYA 3GMEA 3WU3A 2BV3A 3T1YI 1XXEA 2OI2A 3P3GA 2VQEE 1OJ4A 4P7AA 4DR7E 3D4JA 4IFDA 1XMQI 2PNZA 1NHIA 2F1DA 2A2DA 3CDJA 5C0XC 5BR8E 4LF8I 2BM1A 3V5RA 3QT7A 4HY1A 4B3SE 3PYFA 2C39B 1N34I 5K36B 2NN6B 4JI8E 3GLLA 2JT2A 3PYEA 3ZZTA 3J81Q 4QNJA 1ZM4A 1XNQI 2CVEA 2X7IA 1ZM2A 2BM0A 3UHMA 2UU9E 4DR6E 5JEAD 5JEAE 4BA2B 1P42A 3T1HI 4OO1F 1MG7A 4DV0I 5FLXC 2GO3A 4FN5A 5EL9A 1PVGA 4JI7E 4GQUA 4PRXA 4LFAI 4DR1E 2GS8A 4AQYE 4LF4E 1QZRA 3DD6A 1Y6ZA 1HK7A 4DU8A 3P76A 2BA0G 3J81C 3K1JA 4EMDA 2UXDE 4JYAI 1H72C 2VQFI 4DR7I 4DV6E 3JAMQ 2V2VA 3LTOA 4Z7YA 4IFDF 5IT9Q 2DEJA 1D6TA 2DEIA 5LMUE 1KTVA 4LF5E 4B3RE 4OX9I 4LFCE 1IBKI 1FI4A 4OO1C 2JE6A 1UEKA 4DUYE 1XNRE 4LF7E 2NN6D 1IBLE 2O3ZA 1MU5A 1B62A 4DPUA 5IT9C 4JI6E 4KHPI 4DR3E 4LFBE 1Z0BA 1Z0VA 2HKJA 2VF3A 4AIDA 5IWAI 5L3JA 1KKHA 3Q6MA 4DR4E 2IESA 1RR9A 3L7ZA 2WP8B 4JI1I 3PS2A 1S16A 1R6LA 1YHCA 5DNLA 4QNKA 3H4LA 4FW3A 4DR5I 4DPXA 4DR2I 4JI4I 3B4TA 2R3VA 1HNZI 4MQYA 2CGEA 3M6AA 2HHHE 5LL6R 1I94I 5FWKA 4FW5A 3M85G 1Z0TA 4WUBA 4DV2I 4FW9A 3ZM7A 4B3MI 4DV4I 2UXBI 4N3OA 2IOPA 1Z0EA 1YH8A 4DV1E 5LMNI 4RPFA 2HK3A 2E5LI 4LCHA 4DV5E 4DV7E 1NHHA 5C0XB 1EI1A 4NXNI 2UUCE 4YHHI 2PNZB 1B63A 4LFCI 4P52A 4DV3I 2C37A
chains in the Genus database with same CATH topology
2GO3A 4MDTA 4U3BA 4FW5A 2IERA 4FW4A 2IESA 4FW7A 3P3EA 3P3CA 4OZEA 2GO4A 4FW6A 3PS1A 1YH8A 3NZKA 2JT2A 3PS2A 4OKGA 2VESA 4U3DA 1YHCA 1XXEA 4ISAA 4LCHA 3P76A 3P3GA 3UHMA 4FW3A 4J3DA 4IS9A 4MQYA 4LCFA 5DROA 5DRPA 5DRRA 4LCGA 1P42A 2J65A 2O3ZA 3U1YA 5DRQA 3PS3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GO3 A;  4MDT A;  4U3B A;  4FW5 A;  2IER A;  4FW4 A;  2IES A;  4FW7 A;  3P3E A;  3P3C A;  4OZE A;  2GO4 A;  4FW6 A;  3PS1 A;  1YH8 A;  3NZK A;  2JT2 A;  3PS2 A;  4OKG A;  2VES A;  4U3D A;  1YHC A;  1XXE A;  4ISA A;  4LCH A;  3P76 A;  3P3G A;  3UHM A;  4FW3 A;  4J3D A;  4IS9 A;  4MQY A;  4LCF A;  5DRO A;  5DRP A;  5DRR A;  4LCG A;  1P42 A;  2J65 A;  2O3Z A;  3U1Y A;  5DRQ A;  3PS3 A; 
#chains in the Genus database with same CATH topology
 3CDI A;  1XMQ E;  1UDN A;  4JI2 I;  5DNX A;  4X66 I;  3M7N G;  4USM A;  4DR3 I;  4LFB I;  1OYR A;  1Z5B A;  1H74 A;  3P3E A;  4WUC A;  3F0N A;  4JG4 A;  4NXM E;  4LF6 I;  4R1F A;  3K85 A;  2UXC I;  4AM3 A;  1HNX I;  2PO1 A;  2ZM6 E;  4IFD E;  5A2Q Q;  2WP8 A;  2O1T A;  5BR8 I;  4LF8 E;  1EA6 A;  2F4V E;  4IZJ B;  4DUZ E;  1Z59 A;  2HK2 A;  1NHJ A;  4DV0 E;  4AIM A;  2GQ0 A;  4X64 I;  1N36 I;  2PO2 A;  1N0U A;  1HR0 I;  1E3P A;  4B3M E;  1A6F A;  2UXB E;  2NN6 C;  2NN6 F;  2UUB I;  4JI3 I;  3T1Y E;  4DV1 I;  1N0V C;  2UUA E;  3J80 Q;  1H73 A;  4XTJ A;  4MU0 A;  4HAC B;  2C37 B;  4NXN E;  4JI0 E;  5JEA C;  4LFA E;  4IZK B;  4PRV A;  4LPF A;  4ZVI A;  5C0X D;  2IER A;  1N32 E;  3QT6 A;  3ZZU A;  4FWG A;  3ZZ0 A;  4BA1 B;  1Y60 A;  4GKJ E;  3PYD A;  4Z7C A;  2VES A;  5K36 C;  2PNL A;  4NBQ A;  1XMO E;  1R6M A;  4B3T I;  4DXL A;  1HNW E;  2JE6 B;  4LF5 I;  4B3R I;  2V2Q A;  4URL A;  4BA2 A;  1FJG I;  3LNU A;  5DRR A;  2J65 A;  1H7S A;  1HNX E;  4DU7 A;  4DR6 I;  5ELW A;  4FWH A;  5LMU I;  4GKK E;  1ZM9 A;  1N33 E;  3OTO E;  2C39 A;  2F4V I;  2PO2 B;  3J80 C;  3J7A G;  3HKM A;  2VQE I;  2XEX A;  3QT8 A;  4IZJ D;  4X64 E;  2LJP A;  1N36 E;  4J3D A;  5JEA A;  4LCF A;  2AE8 A;  4YY3 I;  5GME A;  2HFU A;  5DRQ A;  1J5E E;  4DR5 E;  2NN6 A;  2PNM A;  1XHK A;  3ZKD A;  1Z5A A;  1FWK A;  4HXZ A;  4BA1 A;  5A2Q C;  4X62 E;  4MU4 A;  3B78 A;  4OZE A;  3K17 A;  4DPY A;  3HJC A;  4IFD C;  4LF9 E;  4IZK A;  3Q6N A;  4DR2 E;  4IFD D;  3PRY A;  2NPF A;  5C0X A;  3PYG A;  4DPW A;  3T1H E;  1IBM I;  4X65 E;  2V8P A;  5DRP A;  1ELO A;  2CG9 A;  3U1Y A;  1HNW I;  5C0X E;  3M7N D;  4OO1 B;  2V34 A;  3GON A;  4MYT A;  4KHP E;  3WU5 A;  1H7U A;  4DV3 E;  3HUL A;  4FW4 A;  1U2R A;  4JI5 E;  3KRN A;  3ZKB A;  4B3S I;  4DV7 I;  1N34 E;  3WU6 A;  3OTO I;  1E3H A;  1Z0G A;  2UXD I;  4YHH E;  5K36 F;  1VIS A;  4NXM I;  2HFS A;  2VQF E;  2O1U A;  2PO1 B;  5DRO A;  1VI7 A;  2WNR A;  2Z5C A;  4DV6 I;  1FWL A;  1HNZ E;  3J7A M;  2X36 A;  4X66 E;  2PO0 B;  2O1V A;  3Q1Q A;  1BKN A;  5K36 E;  1USU A;  1XNQ E;  4FW7 A;  4LF6 E;  4JV5 E;  4LOM A;  3P3C A;  4DPT A;  3L7Z B;  2JEB B;  4M1K A;  2AJ4 A;  4LF4 I;  1IBK E;  1Z0W A;  4X62 I;  2UU9 I;  4DUY I;  1XNR I;  3H1C A;  1FKA E;  4LF7 I;  1KIJ A;  2ZM6 I;  2BA1 D;  2CZ9 A;  4DV5 I;  1WUU A;  1HR0 E;  1IBL I;  4ED4 A;  4JI3 E;  4JI6 I;  4JI7 I;  4HYM A;  1S4E A;  4JYA E;  2BR2 B;  3M85 D;  4USK A;  4X65 I;  4DR4 I;  2BA0 D;  2O1W A;  4IFD B;  5FLX Q;  2HKE A;  4MYU A;  2JEA B;  2C38 B;  2C38 A;  2JEA A;  3PS1 A;  3NZK A;  2IOQ A;  2UUB E;  4JI5 I;  4OO1 D;  1Y5Y A;  4OO1 E;  5JEA F;  3P06 A;  1PIE A;  1Y4S A;  4K0K I;  2Q2E B;  2NN6 E;  3B82 A;  2UXC E;  1UDO A;  4KQV A;  1K47 A;  4LCG A;  1PKP A;  3QT5 A;  2R42 A;  3PS3 A;  1ZXM A;  4IZJ A;  1RRE A;  4MU1 A;  1Z0C A;  4U3B A;  4OO1 A;  1FJG E;  3JAM C;  1OYP A;  3LPS A;  4GKJ I;  4DUZ I;  3B8H A;  4OX9 E;  2BA1 G;  5LMN E;  4B3T E;  4UT4 A;  2GO4 A;  5C0X F;  1N33 I;  1MX0 A;  2PO0 A;  2Z5E A;  4JV5 I;  2UUC I;  4MU3 A;  4PU9 A;  3WU4 A;  2ZIT A;  4HAC A;  4IS9 A;  1ZM3 A;  1DAR A;  4WUD A;  2UUA I;  1FNM A;  2JEB A;  5EKW A;  5IWA E;  4JI4 E;  5K36 D;  1ZXN A;  4JI2 E;  3CWV A;  3V2U C;  4YY3 E;  1UDS A;  1UDQ A;  4JI0 I;  1J5E I;  2EFG A;  4JI8 I;  4UTG A;  4JI1 E;  2A2C A;  3U1K A;  2Z5B B;  1OYS A;  2BR2 A;  5JEA B;  4DV2 E;  1N32 I;  5K36 A;  4OKG A;  4U3D A;  2WNR B;  2Z5C B;  1Z5C A;  1USV A;  4ISA A;  1XMO I;  2V2Z A;  2J7K A;  4I3H A;  2WW4 A;  4LF9 I;  2HHH I;  1I94 E;  4K0K E;  4DR1 I;  1NZ0 A;  2Z5B A;  1IBM E;  4MDT A;  4DV4 E;  4AQY I;  1Y4U A;  2E1R A;  2ZBK B;  4FWD A;  1KVK A;  2E5L E;  3GCM A;  5GMD A;  4FW6 A;  4GKK I;  1RHY A;  3GME A;  3WU3 A;  2BV3 A;  3T1Y I;  1XXE A;  2OI2 A;  3P3G A;  2VQE E;  1OJ4 A;  4P7A A;  4DR7 E;  3D4J A;  4IFD A;  1XMQ I;  2PNZ A;  1NHI A;  2F1D A;  2A2D A;  3CDJ A;  5C0X C;  5BR8 E;  4LF8 I;  2BM1 A;  3V5R A;  3QT7 A;  4HY1 A;  4B3S E;  3PYF A;  2C39 B;  1N34 I;  5K36 B;  2NN6 B;  4JI8 E;  3GLL A;  2JT2 A;  3PYE A;  3ZZT A;  3J81 Q;  4QNJ A;  1ZM4 A;  1XNQ I;  2CVE A;  2X7I A;  1ZM2 A;  2BM0 A;  3UHM A;  2UU9 E;  4DR6 E;  5JEA D;  5JEA E;  4BA2 B;  1P42 A;  3T1H I;  4OO1 F;  1MG7 A;  4DV0 I;  5FLX C;  2GO3 A;  4FN5 A;  5EL9 A;  1PVG A;  4JI7 E;  4GQU A;  4PRX A;  4LFA I;  4DR1 E;  2GS8 A;  4AQY E;  4LF4 E;  1QZR A;  3DD6 A;  1Y6Z A;  1HK7 A;  4DU8 A;  3P76 A;  2BA0 G;  3J81 C;  3K1J A;  4EMD A;  2UXD E;  4JYA I;  1H72 C;  2VQF I;  4DR7 I;  4DV6 E;  3JAM Q;  2V2V A;  3LTO A;  4Z7Y A;  4IFD F;  5IT9 Q;  2DEJ A;  1D6T A;  2DEI A;  5LMU E;  1KTV A;  4LF5 E;  4B3R E;  4OX9 I;  4LFC E;  1IBK I;  1FI4 A;  4OO1 C;  2JE6 A;  1UEK A;  4DUY E;  1XNR E;  4LF7 E;  2NN6 D;  1IBL E;  2O3Z A;  1MU5 A;  1B62 A;  4DPU A;  5IT9 C;  4JI6 E;  4KHP I;  4DR3 E;  4LFB E;  1Z0B A;  1Z0V A;  2HKJ A;  2VF3 A;  4AID A;  5IWA I;  5L3J A;  1KKH A;  3Q6M A;  4DR4 E;  2IES A;  1RR9 A;  3L7Z A;  2WP8 B;  4JI1 I;  3PS2 A;  1S16 A;  1R6L A;  1YHC A;  5DNL A;  4QNK A;  3H4L A;  4FW3 A;  4DR5 I;  4DPX A;  4DR2 I;  4JI4 I;  3B4T A;  2R3V A;  1HNZ I;  4MQY A;  2CGE A;  3M6A A;  2HHH E;  5LL6 R;  1I94 I;  5FWK A;  4FW5 A;  3M85 G;  1Z0T A;  4WUB A;  4DV2 I;  4FW9 A;  3ZM7 A;  4B3M I;  4DV4 I;  2UXB I;  4N3O A;  2IOP A;  1Z0E A;  1YH8 A;  4DV1 E;  5LMN I;  4RPF A;  2HK3 A;  2E5L I;  4LCH A;  4DV5 E;  4DV7 E;  1NHH A;  5C0X B;  1EI1 A;  4NXN I;  2UUC E;  4YHH I;  2PNZ B;  1B63 A;  4LFC I;  4P52 A;  4DV3 I;  2C37 A; 
#chains in the Genus database with same CATH homology
 2GO3 A;  4MDT A;  4U3B A;  4FW5 A;  2IER A;  4FW4 A;  2IES A;  4FW7 A;  3P3E A;  3P3C A;  4OZE A;  2GO4 A;  4FW6 A;  3PS1 A;  1YH8 A;  3NZK A;  2JT2 A;  3PS2 A;  4OKG A;  2VES A;  4U3D A;  1YHC A;  1XXE A;  4ISA A;  4LCH A;  3P76 A;  3P3G A;  3UHM A;  4FW3 A;  4J3D A;  4IS9 A;  4MQY A;  4LCF A;  5DRO A;  5DRP A;  5DRR A;  4LCG A;  1P42 A;  2J65 A;  2O3Z A;  3U1Y A;  5DRQ A;  3PS3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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