4OKGA

Lpxc from p.aeruginosa with the inhibitor 6-(benzimidazol-1-yl)-5-[4-[2-[6-[(4-methylpiperazin-1-yl)methyl]-3-pyridyl]ethynyl]phenyl]pyridine-3-carbohydroxamic acid
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
299
structure length
299
Chain Sequence
MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFSRTDLDPVVEIPARAENVGETTMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQEQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTSFVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKILDAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRP
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Overexpression of Pseudomonas aeruginosa LpxC in the Presence of an Inhibitor in an acrB Deletion Escherichia coli strain for Structural Studies
rcsb
source organism Pseudomonas aeruginosa
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase
total genus 88
structure length 299
sequence length 299
chains with identical sequence B
ec nomenclature ec 3.5.1.108: UDP-3-O-acyl-N-acetylglucosamine deacetylase.
pdb deposition date 2014-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03331 LpxC UDP-3-O-acyl N-acetylglycosamine deacetylase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.230.20 Alpha Beta 2-Layer Sandwich Ribosomal Protein S5; domain 2 lpxc deacetylase, domain 1 4okgA01
3.30.1700.10 Alpha Beta 2-Layer Sandwich lpxc deacetylase, domain 1 lpxc deacetylase, domain 2 4okgA02
4FW4A 2GO3A 4IS9A 4ISAA 4LCGA 3NZKA 3P3CA 2J65A 1YH8A 2IERA 4MQYA 3U1YA 3P3EA 5DRRA 3P3GA 1XXEA 4OKGA 4FW3A 1YHCA 4OZEA 3PS3A 4J3DA 3PS2A 4LCFA 3UHMA 5DROA 4U3DA 4U3BA 1P42A 4FW5A 4FW7A 2O3ZA 3P76A 2JT2A 5DRQA 4MDTA 4FW6A 2VESA 2IESA 5DRPA 3PS1A 4LCHA 2GO4A
chains in the Genus database with same CATH superfamily
4LFCE 4Z7CA 3M85G 3WU6A 4X62E 2R3VA 1YH8A 2DEIA 2HHHE 2Z5BA 1VI7A 3ZZUA 4YY3I 1IBKE 2UUBI 4BA1A 1FJGE 4N3OA 3JAMQ 2GQ0A 1IBMI 4JI2I 3LNUA 4K0KI 1Z59A 2NN6D 2O1WA 4GQUA 4DUZE 4LFAI 2JT2A 4MYUA 1HNZE 4B3SI 3B78A 4B3RI 3T1YI 4BA2A 2NN6F 1HR0I 2HKEA 4MU0A 4YY3E 4IFDE 2NN6A 5K36A 2UUAE 1XNQE 5GMDA 4LF5E 1U2RA 1Z0WA 4IZJA 5LMUI 1ZM4A 1J5EE 2VF3A 3JAMC 2Z5CB 4LFAE 4LF8E 4DR6I 4JI0I 1D6TA 1I94E 3J80Q 3T1HE 4JV5E 4LF5I 4X66I 1DARA 2C39A 5LMNE 4GKKI 5C0XE 4P7AA 1J5EI 3J81C 3D4JA 4FWHA 5K36C 4LF8I 1Z0GA 1Z0CA 3CWVA 2BA0G 4JI0E 4PRXA 4B3TI 4MQYA 1XMQI 3L7ZA 3J80C 4FWGA 4BA1B 2DEJA 4OO1F 4YHHE 5K36D 4DR3I 3Q6NA 4U3DA 4JI5E 2V8PA 3T1YE 2LJPA 4LF7E 1Z5AA 1Z5CA 5JEAD 4KQVA 1BKNA 4UT4A 4OO1C 4LCGA 4ISAA 3WU3A 2O1TA 3P3CA 1NHJA 1N0VC 2HK2A 4LF4E 2BA1G 4DV4E 4QNJA 4JI8I 5DROA 3J81Q 2VQFI 1KVKA 2C39B 2BV3A 1HNZI 4B3SE 3J7AM 2IESA 2E5LI 4NXNE 4X64E 2R42A 3ZKBA 2UU9I 2IERA 4DR7I 4DPWA 1MU5A 4DR2I 4R1FA 1UDOA 1N34E 1XXEA 1Z0BA 1ZM2A 4JI1I 4JG4A 2Q2EB 4DR3E 3QT5A 2GS8A 4X64I 2BA1D 2IOQA 4DV5E 3WU5A 4JV5I 4JYAE 4LF7I 2NN6E 3B8HA 4Z7YA 5LMNI 4DR7E 3U1KA 1ELOA 2VESA 5ELWA 5IT9C 4OO1E 5GMEA 1N34I 1H72C 3GLLA 4FN5A 2UXDE 3HJCA 2X7IA 4DPXA 4JI4I 2PO0A 5L3JA 1HNXI 4JI3I 4IZJD 3WU4A 4B3TE 4LF4I 4DV5I 4DV4I 4OO1D 2UXBE 2JEAA 4USKA 2PNLA 2WW4A 2PO2B 3LPSA 3PS2A 4IFDC 4LF9I 3K85A 4AIMA 2C37B 4X62I 2O1UA 1KTVA 1ZM9A 4JI4E 4LPFA 4ED4A 3P76A 1E3PA 1EA6A 2WNRB 1Y6ZA 4DR4I 1IBME 4JI2E 4P52A 4K0KE 1Y4SA 1IBLE 4DV3E 3Q6MA 4LFBE 4DUZI 1FI4A 4RPFA 4LF6I 1ZXMA 1H7SA 2Z5CA 4AIDA 4NXMI 1YHCA 4B3ME 2XEXA 2O1VA 2Z5EA 2ZBKB 4DR4E 2UXCI 2VQEI 1IBLI 2O3ZA 4DR6E 4AQYI 4IFDF 1E3HA 1UDNA 2UXCE 2UU9E 5LL6R 3B4TA 2VQEE 1NZ0A 1RHYA 5FLXQ 1H73A 2JEAB 4FW3A 1H7UA 4LCFA 2NPFA 4DR5E 4OX9I 5EL9A 1P42A 4XTJA 1XMQE 1A6FA 2CVEA 3KRNA 2EFGA 2V2VA 3DD6A 1FNMA 4YHHI 1NHIA 1OYSA 4IS9A 4JI6I 2JEBB 1HNXE 3QT6A 4JI3E 2J65A 4OX9E 4NBQA 3P3EA 2HKJA 4WUBA 1S4EA 3Q1QA 4HACB 2V2ZA 5A2QC 4LF9E 1N32I 4OO1A 4WUDA 2HFUA 3ZZ0A 2AE8A 1Z5BA 4FW5A 2UUCE 4DV2I 4DV0I 1PVGA 4AM3A 5DRPA 2NN6C 5K36B 2NN6B 4MYTA 4FW4A 2ZM6E 1MG7A 5JEAC 3K17A 2VQFE 4DV3I 4WUCA 1N32E 3M7ND 4LFBI 3L7ZB 5A2QQ 3CDIA 4IFDB 4LF6E 2UUCI 3P3GA 1Y4UA 4ZVIA 2PO1B 4NXNI 4DPYA 2E5LE 4LOMA 4URLA 4DUYI 4I3HA 4B3MI 2OI2A 5DNLA 2HFSA 3M7NG 1PIEA 3GMEA 1OYRA 3J7AG 1MX0A 5IWAI 4JI1E 4DR1I 3PS1A 4JI6E 4X65E 2PNZA 3P06A 4U3BA 2V34A 3CDJA 4IZKB 1N36I 2Z5BB 2A2DA 1VISA 1KIJA 5C0XC 1N0UA 2PO1A 4DV7E 5IWAE 4DU8A 4JI7E 2UXDI 5JEAB 1KKHA 1R6LA 4DV2E 2C37A 1UDQA 3PRYA 1N36E 5FWKA 2E1RA 2F4VE 2AJ4A 5K36F 2ZM6I 4DPTA 1EI1A 2PO0B 4JI7I 3QT7A 3V5RA 4QNKA 4IZKA 3ZM7A 4DV1I 3PYGA 1S16A 3H4LA 3QT8A 2J7KA 1Z0TA 4HYMA 4OKGA 1HR0E 5IT9Q 1ZXNA 2CGEA 5C0XD 2JE6A 3M85D 4OO1B 1ZM3A 3ZZTA 1XNRI 4MU1A 3B82A 4FW6A 4DV1E 2WNRA 3PYFA 5C0XF 2CZ9A 4MU3A 4X65I 4NXME 3K1JA 2BR2A 2GO4A 1XHKA 4FW9A 2A2CA 3PYEA 3NZKA 1HK7A 1XMOI 4GKJE 3M6AA 1XNRE 4DV7I 2PO2A 4J3DA 4AQYE 1OYPA 4DUYE 2C38A 1N33E 2CG9A 3H1CA 4UTGA 4PRVA 2BA0D 4DV6I 4BA2B 1XMOE 1UDSA 1FWLA 1UEKA 4DPUA 4DR1E 1B63A 4DR5I 4MDTA 4LFCI 4FWDA 2GO3A 1WUUA 2WP8A 3V2UC 2HHHI 2X36A 2JEBA 2V2QA 4IFDA 3U1YA 1RREA 4MU4A 5JEAE 3F0NA 1K47A 1IBKI 2UUBE 4HY1A 3OTOE 2BM0A 1B62A 1FWKA 1USVA 1OJ4A 5DRQA 5BR8I 4B3RE 2F4VI 4KHPI 1USUA 3ZKDA 2PNMA 2PNZB 2BR2B 2UUAI 4LCHA 1XNQI 4JI8E 5FLXC 2WP8B 1RR9A 1Y5YA 5EKWA 4PU9A 4DV0E 5DRRA 5BR8E 1QZRA 4OZEA 3PS3A 4KHPE 1N33I 3HULA 1I94I 4DU7A 3T1HI 3UHMA 2C38B 1FJGI 2HK3A 3GONA 1NHHA 2IOPA 2F1DA 4FW7A 4GKKE 5K36E 4DR2E 4M1KA 4HXZA 4USMA 1PKPA 1Y60A 1FKAE 4IZJB 4JYAI 3GCMA 1HNWE 4GKJI 4IFDD 3OTOI 5LMUE 1R6MA 1Z0EA 4HACA 3PYDA 5DNXA 2BM1A 5C0XA 4EMDA 5JEAA 5C0XB 2JE6B 4JI5I 1Z0VA 5JEAF 4DXLA 3LTOA 2UXBI 3HKMA 4DV6E 4X66E 1HNWI 2ZITA 1H74A
chains in the Genus database with same CATH topology
4FW4A 2GO3A 4IS9A 4ISAA 4LCGA 3NZKA 3P3CA 2J65A 1YH8A 2IERA 4MQYA 3U1YA 3P3EA 5DRRA 3P3GA 1XXEA 4OKGA 4FW3A 1YHCA 4OZEA 3PS3A 4J3DA 3PS2A 4LCFA 3UHMA 5DROA 4U3DA 4U3BA 1P42A 4FW5A 4FW7A 2O3ZA 3P76A 2JT2A 5DRQA 4MDTA 4FW6A 2VESA 2IESA 5DRPA 3PS1A 4LCHA 2GO4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FW4 A;  2GO3 A;  4IS9 A;  4ISA A;  4LCG A;  3NZK A;  3P3C A;  2J65 A;  1YH8 A;  2IER A;  4MQY A;  3U1Y A;  3P3E A;  5DRR A;  3P3G A;  1XXE A;  4OKG A;  4FW3 A;  1YHC A;  4OZE A;  3PS3 A;  4J3D A;  3PS2 A;  4LCF A;  3UHM A;  5DRO A;  4U3D A;  4U3B A;  1P42 A;  4FW5 A;  4FW7 A;  2O3Z A;  3P76 A;  2JT2 A;  5DRQ A;  4MDT A;  4FW6 A;  2VES A;  2IES A;  5DRP A;  3PS1 A;  4LCH A;  2GO4 A; 
#chains in the Genus database with same CATH topology
 4LFC E;  4Z7C A;  3M85 G;  3WU6 A;  4X62 E;  2R3V A;  1YH8 A;  2DEI A;  2HHH E;  2Z5B A;  1VI7 A;  3ZZU A;  4YY3 I;  1IBK E;  2UUB I;  4BA1 A;  1FJG E;  4N3O A;  3JAM Q;  2GQ0 A;  1IBM I;  4JI2 I;  3LNU A;  4K0K I;  1Z59 A;  2NN6 D;  2O1W A;  4GQU A;  4DUZ E;  4LFA I;  2JT2 A;  4MYU A;  1HNZ E;  4B3S I;  3B78 A;  4B3R I;  3T1Y I;  4BA2 A;  2NN6 F;  1HR0 I;  2HKE A;  4MU0 A;  4YY3 E;  4IFD E;  2NN6 A;  5K36 A;  2UUA E;  1XNQ E;  5GMD A;  4LF5 E;  1U2R A;  1Z0W A;  4IZJ A;  5LMU I;  1ZM4 A;  1J5E E;  2VF3 A;  3JAM C;  2Z5C B;  4LFA E;  4LF8 E;  4DR6 I;  4JI0 I;  1D6T A;  1I94 E;  3J80 Q;  3T1H E;  4JV5 E;  4LF5 I;  4X66 I;  1DAR A;  2C39 A;  5LMN E;  4GKK I;  5C0X E;  4P7A A;  1J5E I;  3J81 C;  3D4J A;  4FWH A;  5K36 C;  4LF8 I;  1Z0G A;  1Z0C A;  3CWV A;  2BA0 G;  4JI0 E;  4PRX A;  4B3T I;  4MQY A;  1XMQ I;  3L7Z A;  3J80 C;  4FWG A;  4BA1 B;  2DEJ A;  4OO1 F;  4YHH E;  5K36 D;  4DR3 I;  3Q6N A;  4U3D A;  4JI5 E;  2V8P A;  3T1Y E;  2LJP A;  4LF7 E;  1Z5A A;  1Z5C A;  5JEA D;  4KQV A;  1BKN A;  4UT4 A;  4OO1 C;  4LCG A;  4ISA A;  3WU3 A;  2O1T A;  3P3C A;  1NHJ A;  1N0V C;  2HK2 A;  4LF4 E;  2BA1 G;  4DV4 E;  4QNJ A;  4JI8 I;  5DRO A;  3J81 Q;  2VQF I;  1KVK A;  2C39 B;  2BV3 A;  1HNZ I;  4B3S E;  3J7A M;  2IES A;  2E5L I;  4NXN E;  4X64 E;  2R42 A;  3ZKB A;  2UU9 I;  2IER A;  4DR7 I;  4DPW A;  1MU5 A;  4DR2 I;  4R1F A;  1UDO A;  1N34 E;  1XXE A;  1Z0B A;  1ZM2 A;  4JI1 I;  4JG4 A;  2Q2E B;  4DR3 E;  3QT5 A;  2GS8 A;  4X64 I;  2BA1 D;  2IOQ A;  4DV5 E;  3WU5 A;  4JV5 I;  4JYA E;  4LF7 I;  2NN6 E;  3B8H A;  4Z7Y A;  5LMN I;  4DR7 E;  3U1K A;  1ELO A;  2VES A;  5ELW A;  5IT9 C;  4OO1 E;  5GME A;  1N34 I;  1H72 C;  3GLL A;  4FN5 A;  2UXD E;  3HJC A;  2X7I A;  4DPX A;  4JI4 I;  2PO0 A;  5L3J A;  1HNX I;  4JI3 I;  4IZJ D;  3WU4 A;  4B3T E;  4LF4 I;  4DV5 I;  4DV4 I;  4OO1 D;  2UXB E;  2JEA A;  4USK A;  2PNL A;  2WW4 A;  2PO2 B;  3LPS A;  3PS2 A;  4IFD C;  4LF9 I;  3K85 A;  4AIM A;  2C37 B;  4X62 I;  2O1U A;  1KTV A;  1ZM9 A;  4JI4 E;  4LPF A;  4ED4 A;  3P76 A;  1E3P A;  1EA6 A;  2WNR B;  1Y6Z A;  4DR4 I;  1IBM E;  4JI2 E;  4P52 A;  4K0K E;  1Y4S A;  1IBL E;  4DV3 E;  3Q6M A;  4LFB E;  4DUZ I;  1FI4 A;  4RPF A;  4LF6 I;  1ZXM A;  1H7S A;  2Z5C A;  4AID A;  4NXM I;  1YHC A;  4B3M E;  2XEX A;  2O1V A;  2Z5E A;  2ZBK B;  4DR4 E;  2UXC I;  2VQE I;  1IBL I;  2O3Z A;  4DR6 E;  4AQY I;  4IFD F;  1E3H A;  1UDN A;  2UXC E;  2UU9 E;  5LL6 R;  3B4T A;  2VQE E;  1NZ0 A;  1RHY A;  5FLX Q;  1H73 A;  2JEA B;  4FW3 A;  1H7U A;  4LCF A;  2NPF A;  4DR5 E;  4OX9 I;  5EL9 A;  1P42 A;  4XTJ A;  1XMQ E;  1A6F A;  2CVE A;  3KRN A;  2EFG A;  2V2V A;  3DD6 A;  1FNM A;  4YHH I;  1NHI A;  1OYS A;  4IS9 A;  4JI6 I;  2JEB B;  1HNX E;  3QT6 A;  4JI3 E;  2J65 A;  4OX9 E;  4NBQ A;  3P3E A;  2HKJ A;  4WUB A;  1S4E A;  3Q1Q A;  4HAC B;  2V2Z A;  5A2Q C;  4LF9 E;  1N32 I;  4OO1 A;  4WUD A;  2HFU A;  3ZZ0 A;  2AE8 A;  1Z5B A;  4FW5 A;  2UUC E;  4DV2 I;  4DV0 I;  1PVG A;  4AM3 A;  5DRP A;  2NN6 C;  5K36 B;  2NN6 B;  4MYT A;  4FW4 A;  2ZM6 E;  1MG7 A;  5JEA C;  3K17 A;  2VQF E;  4DV3 I;  4WUC A;  1N32 E;  3M7N D;  4LFB I;  3L7Z B;  5A2Q Q;  3CDI A;  4IFD B;  4LF6 E;  2UUC I;  3P3G A;  1Y4U A;  4ZVI A;  2PO1 B;  4NXN I;  4DPY A;  2E5L E;  4LOM A;  4URL A;  4DUY I;  4I3H A;  4B3M I;  2OI2 A;  5DNL A;  2HFS A;  3M7N G;  1PIE A;  3GME A;  1OYR A;  3J7A G;  1MX0 A;  5IWA I;  4JI1 E;  4DR1 I;  3PS1 A;  4JI6 E;  4X65 E;  2PNZ A;  3P06 A;  4U3B A;  2V34 A;  3CDJ A;  4IZK B;  1N36 I;  2Z5B B;  2A2D A;  1VIS A;  1KIJ A;  5C0X C;  1N0U A;  2PO1 A;  4DV7 E;  5IWA E;  4DU8 A;  4JI7 E;  2UXD I;  5JEA B;  1KKH A;  1R6L A;  4DV2 E;  2C37 A;  1UDQ A;  3PRY A;  1N36 E;  5FWK A;  2E1R A;  2F4V E;  2AJ4 A;  5K36 F;  2ZM6 I;  4DPT A;  1EI1 A;  2PO0 B;  4JI7 I;  3QT7 A;  3V5R A;  4QNK A;  4IZK A;  3ZM7 A;  4DV1 I;  3PYG A;  1S16 A;  3H4L A;  3QT8 A;  2J7K A;  1Z0T A;  4HYM A;  4OKG A;  1HR0 E;  5IT9 Q;  1ZXN A;  2CGE A;  5C0X D;  2JE6 A;  3M85 D;  4OO1 B;  1ZM3 A;  3ZZT A;  1XNR I;  4MU1 A;  3B82 A;  4FW6 A;  4DV1 E;  2WNR A;  3PYF A;  5C0X F;  2CZ9 A;  4MU3 A;  4X65 I;  4NXM E;  3K1J A;  2BR2 A;  2GO4 A;  1XHK A;  4FW9 A;  2A2C A;  3PYE A;  3NZK A;  1HK7 A;  1XMO I;  4GKJ E;  3M6A A;  1XNR E;  4DV7 I;  2PO2 A;  4J3D A;  4AQY E;  1OYP A;  4DUY E;  2C38 A;  1N33 E;  2CG9 A;  3H1C A;  4UTG A;  4PRV A;  2BA0 D;  4DV6 I;  4BA2 B;  1XMO E;  1UDS A;  1FWL A;  1UEK A;  4DPU A;  4DR1 E;  1B63 A;  4DR5 I;  4MDT A;  4LFC I;  4FWD A;  2GO3 A;  1WUU A;  2WP8 A;  3V2U C;  2HHH I;  2X36 A;  2JEB A;  2V2Q A;  4IFD A;  3U1Y A;  1RRE A;  4MU4 A;  5JEA E;  3F0N A;  1K47 A;  1IBK I;  2UUB E;  4HY1 A;  3OTO E;  2BM0 A;  1B62 A;  1FWK A;  1USV A;  1OJ4 A;  5DRQ A;  5BR8 I;  4B3R E;  2F4V I;  4KHP I;  1USU A;  3ZKD A;  2PNM A;  2PNZ B;  2BR2 B;  2UUA I;  4LCH A;  1XNQ I;  4JI8 E;  5FLX C;  2WP8 B;  1RR9 A;  1Y5Y A;  5EKW A;  4PU9 A;  4DV0 E;  5DRR A;  5BR8 E;  1QZR A;  4OZE A;  3PS3 A;  4KHP E;  1N33 I;  3HUL A;  1I94 I;  4DU7 A;  3T1H I;  3UHM A;  2C38 B;  1FJG I;  2HK3 A;  3GON A;  1NHH A;  2IOP A;  2F1D A;  4FW7 A;  4GKK E;  5K36 E;  4DR2 E;  4M1K A;  4HXZ A;  4USM A;  1PKP A;  1Y60 A;  1FKA E;  4IZJ B;  4JYA I;  3GCM A;  1HNW E;  4GKJ I;  4IFD D;  3OTO I;  5LMU E;  1R6M A;  1Z0E A;  4HAC A;  3PYD A;  5DNX A;  2BM1 A;  5C0X A;  4EMD A;  5JEA A;  5C0X B;  2JE6 B;  4JI5 I;  1Z0V A;  5JEA F;  4DXL A;  3LTO A;  2UXB I;  3HKM A;  4DV6 E;  4X66 E;  1HNW I;  2ZIT A;  1H74 A; 
#chains in the Genus database with same CATH homology
 4FW4 A;  2GO3 A;  4IS9 A;  4ISA A;  4LCG A;  3NZK A;  3P3C A;  2J65 A;  1YH8 A;  2IER A;  4MQY A;  3U1Y A;  3P3E A;  5DRR A;  3P3G A;  1XXE A;  4OKG A;  4FW3 A;  1YHC A;  4OZE A;  3PS3 A;  4J3D A;  3PS2 A;  4LCF A;  3UHM A;  5DRO A;  4U3D A;  4U3B A;  1P42 A;  4FW5 A;  4FW7 A;  2O3Z A;  3P76 A;  2JT2 A;  5DRQ A;  4MDT A;  4FW6 A;  2VES A;  2IES A;  5DRP A;  3PS1 A;  4LCH A;  2GO4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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