4OOCA

Dehydratase domain of the polyketide ppsc from mycobacterium tuberculosis
Total Genus 65
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
65
sequence length
294
structure length
268
Chain Sequence
DTHPLLGVGVTDPTNGTRVWESELDPDLLWLADHVIDDLVVLPGAAYAEIALAAATDTFAVEQDQPWMISELDLRQMLHVTPGTVLVTTLTGDEQRCQVEIRTRSGSSGWTTHATATVARAEPLTADLEDQLDPDDLYQRLRGAGQQHGPAFQGIVGLAVTQAGVARAQVRLPASARTGSREFMLHPVMMDIALQTLGATRTATDLSALVVPVRFAGVHVYGDITRGVRAVGSLAAAGDRLVGEVVLTDANGQPLLVVDEVEMAVLGS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Insights into the catalytic mechanism of the DH domain of the Mycobacterium tuberculosis polyketide synthase PpsC and architecture of the beta-carbon processing domains
rcsb
molecule tags Transferase
source organism Mycobacterium tuberculosis
molecule keywords Phthiocerol synthesis polyketide synthase type I PpsC
total genus 65
structure length 268
sequence length 294
ec nomenclature ec 2.3.1.41: Beta-ketoacyl-[acyl-carrier-protein] synthase I.
pdb deposition date 2014-01-31
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.10.129.110 Alpha Beta Roll Thiol Ester Dehydrase; Chain A Thiol Ester Dehydrase; Chain A 4oocA00
4LN9A 5E1VA 4U3VA 3KG9A 4OOCA 3EL6A 3HRRA 2VZ8A 5BP2A 5BP3A 3HRQA 5KKUA 3KG6A 2VZ9A 3KG7A 4KC5A
chains in the Genus database with same CATH superfamily
3KX7A 3S4KA 3BBJA 5BUYA 1VPMA 3DP3A 3R3BA 5EO4A 4GAKA 3ZH5A 3F5OA 4H4GA 3KG6A 3TEAA 4E3EA 4KEHA 5BYUA 2CYEA 3LMBA 4R9ZA 2GLLA 4R4UA 3R3FA 4XY6A 3ZH7B 4U3VA 3D6XA 5SZYA 3R36A 1WM6A 2UV8G 3LW3A 2HBOA 3R34A 1SC0A 2O6TA 5HWFA 4MOCA 2C2IA 2XEMA 3R3DA 2PRXA 3P3IA 2FUJA 4CL6A 1SBKA 4B0JA 3R87A 2Q78A 1Q4TA 4XY5A 4A0YA 1Q4SA 1MKBA 5EGKA 4K4DA 3DOYA 2NUJA 4HZNA 5T07A 3DP2A 3B7KA 3E29A 1TBUA 1VH9A 2PIMA 4FFUA 2HLJA 1VH5A 3U0AA 3CF9A 1Y7UA 4NCPA 1PN2A 2DSLA 3KVZA 4RLUB 4ZW0A 4AE7A 3HMJG 3AZ9A 2CY9A 3GEKA 1WLVA 3DP0A 3LZ7A 5BUXA 3KV7A 2W3XA 3AZBA 4HZPA 1Z6BA 4QD8A 2F41A 3KUWA 5SZVA 2GVHA 5F6RA 2EGIA 5DM5A 1NJKA 4ORDA 1Z54A 2EGRA 1Q4UA 3Q62A 2F3XA 3HM0A 4W78B 5KKUA 3D6LA 4GAHA 4RV2A 3KW1A 4K4AA 2H4UA 3ESIA 3KUVA 1PSUA 3CF8A 3HRRA 3R37A 4QD9A 1LO9A 4RLUA 4QDAA 4K00A 5DIOA 4I4JA 3P3FA 4QD7A 3KV8A 2V1OA 2QQPA 3LBEA 3BNVA 4IENA 4MTUA 2B3MA 5BP2A 2EGJA 4RV2B 4A0ZA 4AE8A 4OOBA 4W78A 5EO2A 5HZ4A 3CK1A 1U1ZA 4RMMA 4ZRFA 4B0CA 3KG9A 1YLIA 4A0XA 4MZQA 4RLJA 3E1EA 4B8UA 2VZ9A 1Q6WA 2B6EA 5T02A 1ZHGA 2VZ8A 1IXLA 5T06A 2XFLA 5E1VA 3F1TA 3KG7A 3SPSA 2OKHA 2CWZA 4K4CA 4WNBA 3ZH6A 1J1YA 2GLPA 4HZOA 2QWZA 3WEWA 4RLJB 3E8PA 3EL6A 1YOCA 2F0XA 1S5UA 4I82A 3HRQA 5EP5A 4A12A 3R3AA 3DOZA 3KX8A 5HD6A 3RD7A 3KVUA 3P2RA 3B7JA 3P2SA 3QY3A 4RLTA 3B18A 3KVIA 1C8UA 5CPGA 1S9CA 3EXZA 1IQ6A 1MKAA 2GLVA 3QOOA 1WLUA 1WN3A 3AZAA 3R35A 1LO7A 3KG8A 4I83A 4WNBB 4ZJBA 2BI0A 4LN9A 3DKZA 1T82A 4K02A 4OOCA 2GLMA 2O6BA 4ZV3A 1ZKIA 2OV9A 2Q2BA 3R3CA 1SH8A 1VI8A 2GF6A 3NWZA 4RLTB 3DP1A 5SZZA 2O5UA 4QFWA 3KH8A 4MOBA 5EGLA 2OWNA 4K49A 1PN4A 3S6PA 2OAFA 4RLWA 4M20A 3FRNA 4ZRBA 2AV9A 3HDUA 2FS2A 3KHPA 4I45A 4KC5A 3ED0A 3P2QA 5HMCA 3D04A 5KL9A 3AZ8A 5HMBA 2ESSA 3OMLA 3K67A 4B0IA 3BJKA 1BVQA 4K4BA 3LWGA 1OHFA 3CJYA 2OKIA 2PZHA 4FQ9A 3IR3A 2QQ2A 5BUWA 3RQBA 2VKZG 4RLWB 5SZUA 3LBBA 4B0BA 2O6UA 3R32A 1LO8A 2OIWA 4YBVA 3ZH7A 5EGJA 5BP3A 2PFCA 2EISA 4QDBA 2HX5A
chains in the Genus database with same CATH topology
4LN9A 3BBJA 3HMJG 3KG9A 4OOCA 3ZH5A 3KG6A 2VZ9A 4QFWA 4R9ZA 4R4UA 3ZH7B 4U3VA 3S6PA 2VZ8A 3FRNA 2UV8G 5KKUA 5E1VA 3KG7A 4KC5A 3ZH6A 3EL6A 3HRRA 3HRQA 1OHFA 3CJYA 2QQPA 3RD7A 3RQBA 2VKZG 3B18A 5BP3A 5BP2A 3ZH7A 3U0AA 2PFCA 3KG8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4LN9 A;  5E1V A;  4U3V A;  3KG9 A;  4OOC A;  3EL6 A;  3HRR A;  2VZ8 A;  5BP2 A;  5BP3 A;  3HRQ A;  5KKU A;  3KG6 A;  2VZ9 A;  3KG7 A;  4KC5 A; 
#chains in the Genus database with same CATH topology
 3KX7 A;  3S4K A;  3BBJ A;  5BUY A;  1VPM A;  3DP3 A;  3R3B A;  5EO4 A;  4GAK A;  3ZH5 A;  3F5O A;  4H4G A;  3KG6 A;  3TEA A;  4E3E A;  4KEH A;  5BYU A;  2CYE A;  3LMB A;  4R9Z A;  2GLL A;  4R4U A;  3R3F A;  4XY6 A;  3ZH7 B;  4U3V A;  3D6X A;  5SZY A;  3R36 A;  1WM6 A;  2UV8 G;  3LW3 A;  2HBO A;  3R34 A;  1SC0 A;  2O6T A;  5HWF A;  4MOC A;  2C2I A;  2XEM A;  3R3D A;  2PRX A;  3P3I A;  2FUJ A;  4CL6 A;  1SBK A;  4B0J A;  3R87 A;  2Q78 A;  1Q4T A;  4XY5 A;  4A0Y A;  1Q4S A;  1MKB A;  5EGK A;  4K4D A;  3DOY A;  2NUJ A;  4HZN A;  5T07 A;  3DP2 A;  3B7K A;  3E29 A;  1TBU A;  1VH9 A;  2PIM A;  4FFU A;  2HLJ A;  1VH5 A;  3U0A A;  3CF9 A;  1Y7U A;  4NCP A;  1PN2 A;  2DSL A;  3KVZ A;  4RLU B;  4ZW0 A;  4AE7 A;  3HMJ G;  3AZ9 A;  2CY9 A;  3GEK A;  1WLV A;  3DP0 A;  3LZ7 A;  5BUX A;  3KV7 A;  2W3X A;  3AZB A;  4HZP A;  1Z6B A;  4QD8 A;  2F41 A;  3KUW A;  5SZV A;  2GVH A;  5F6R A;  2EGI A;  5DM5 A;  1NJK A;  4ORD A;  1Z54 A;  2EGR A;  1Q4U A;  3Q62 A;  2F3X A;  3HM0 A;  4W78 B;  5KKU A;  3D6L A;  4GAH A;  4RV2 A;  3KW1 A;  4K4A A;  2H4U A;  3ESI A;  3KUV A;  1PSU A;  3CF8 A;  3HRR A;  3R37 A;  4QD9 A;  1LO9 A;  4RLU A;  4QDA A;  4K00 A;  5DIO A;  4I4J A;  3P3F A;  4QD7 A;  3KV8 A;  2V1O A;  2QQP A;  3LBE A;  3BNV A;  4IEN A;  4MTU A;  2B3M A;  5BP2 A;  2EGJ A;  4RV2 B;  4A0Z A;  4AE8 A;  4OOB A;  4W78 A;  5EO2 A;  5HZ4 A;  3CK1 A;  1U1Z A;  4RMM A;  4ZRF A;  4B0C A;  3KG9 A;  1YLI A;  4A0X A;  4MZQ A;  4RLJ A;  3E1E A;  4B8U A;  2VZ9 A;  1Q6W A;  2B6E A;  5T02 A;  1ZHG A;  2VZ8 A;  1IXL A;  5T06 A;  2XFL A;  5E1V A;  3F1T A;  3KG7 A;  3SPS A;  2OKH A;  2CWZ A;  4K4C A;  4WNB A;  3ZH6 A;  1J1Y A;  2GLP A;  4HZO A;  2QWZ A;  3WEW A;  4RLJ B;  3E8P A;  3EL6 A;  1YOC A;  2F0X A;  1S5U A;  4I82 A;  3HRQ A;  5EP5 A;  4A12 A;  3R3A A;  3DOZ A;  3KX8 A;  5HD6 A;  3RD7 A;  3KVU A;  3P2R A;  3B7J A;  3P2S A;  3QY3 A;  4RLT A;  3B18 A;  3KVI A;  1C8U A;  5CPG A;  1S9C A;  3EXZ A;  1IQ6 A;  1MKA A;  2GLV A;  3QOO A;  1WLU A;  1WN3 A;  3AZA A;  3R35 A;  1LO7 A;  3KG8 A;  4I83 A;  4WNB B;  4ZJB A;  2BI0 A;  4LN9 A;  3DKZ A;  1T82 A;  4K02 A;  4OOC A;  2GLM A;  2O6B A;  4ZV3 A;  1ZKI A;  2OV9 A;  2Q2B A;  3R3C A;  1SH8 A;  1VI8 A;  2GF6 A;  3NWZ A;  4RLT B;  3DP1 A;  5SZZ A;  2O5U A;  4QFW A;  3KH8 A;  4MOB A;  5EGL A;  2OWN A;  4K49 A;  1PN4 A;  3S6P A;  2OAF A;  4RLW A;  4M20 A;  3FRN A;  4ZRB A;  2AV9 A;  3HDU A;  2FS2 A;  3KHP A;  4I45 A;  4KC5 A;  3ED0 A;  3P2Q A;  5HMC A;  3D04 A;  5KL9 A;  3AZ8 A;  5HMB A;  2ESS A;  3OML A;  3K67 A;  4B0I A;  3BJK A;  1BVQ A;  4K4B A;  3LWG A;  1OHF A;  3CJY A;  2OKI A;  2PZH A;  4FQ9 A;  3IR3 A;  2QQ2 A;  5BUW A;  3RQB A;  2VKZ G;  4RLW B;  5SZU A;  3LBB A;  4B0B A;  2O6U A;  3R32 A;  1LO8 A;  2OIW A;  4YBV A;  3ZH7 A;  5EGJ A;  5BP3 A;  2PFC A;  2EIS A;  4QDB A;  2HX5 A; 
#chains in the Genus database with same CATH homology
 4LN9 A;  3BBJ A;  3HMJ G;  3KG9 A;  4OOC A;  3ZH5 A;  3KG6 A;  2VZ9 A;  4QFW A;  4R9Z A;  4R4U A;  3ZH7 B;  4U3V A;  3S6P A;  2VZ8 A;  3FRN A;  2UV8 G;  5KKU A;  5E1V A;  3KG7 A;  4KC5 A;  3ZH6 A;  3EL6 A;  3HRR A;  3HRQ A;  1OHF A;  3CJY A;  2QQP A;  3RD7 A;  3RQB A;  2VKZ G;  3B18 A;  5BP3 A;  5BP2 A;  3ZH7 A;  3U0A A;  2PFC A;  3KG8 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...