4P1YA

Crystal structure of staphylococcal gamma-hemolysin prepore
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
284
structure length
267
Chain Sequence
VTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGAGPYGRDSFHPTYGNELFLAGSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQICWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Gamma-hemolysin component B
publication title Molecular basis of transmembrane beta-barrel formation of staphylococcal pore-forming toxins.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 62
structure length 267
sequence length 284
chains with identical sequence C, E, G
ec nomenclature
pdb deposition date 2014-02-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4p1yA00
4IYAA 1T5RA 4P1YA 4YHDA 2QK7B 4TW1B 2QK7A 1PVLA 4TW1A 4IYCA 5K59A 4IZLA 2YGTA 3LKFA 4U6VA 4P24A 4Q7GA 3B07B 1LKFA 3B07A 3M2LA 2LKFA 4J0OA 3O44A 3ROHA 4H56A 3M4EA 3M3RA 4IDJA 4IYTA 3ANZA 7AHLA 4P1XB 4I0NA 4P1XA 3M4DA 4P1YB 5K59C
chains in the Genus database with same CATH superfamily
4IYAA 1T5RA 4P1YA 4YHDA 2QK7B 4TW1B 2QK7A 1PVLA 4TW1A 4IYCA 5K59A 4IZLA 2YGTA 3LKFA 4U6VA 4P24A 4Q7GA 3B07B 1LKFA 3B07A 3M2LA 2LKFA 4J0OA 3O44A 3ROHA 4H56A 3M4EA 3M3RA 1XEZA 4IDJA 4IYTA 3ANZA 7AHLA 4P1XB 4I0NA 4P1XA 3M4DA 4P1YB 5K59C
chains in the Genus database with same CATH topology
4IYAA 1T5RA 4P1YA 4YHDA 2QK7B 4TW1B 2QK7A 1PVLA 4TW1A 4IYCA 5K59A 4IZLA 2YGTA 3LKFA 4U6VA 4P24A 4Q7GA 3B07B 1LKFA 3B07A 3M2LA 2LKFA 4J0OA 3O44A 3ROHA 4H56A 3M4EA 3M3RA 4IDJA 4IYTA 3ANZA 7AHLA 4P1XB 4I0NA 4P1XA 3M4DA 4P1YB 5K59C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IYA A;  1T5R A;  4P1Y A;  4YHD A;  2QK7 B;  4TW1 B;  2QK7 A;  1PVL A;  4TW1 A;  4IYC A;  5K59 A;  4IZL A;  2YGT A;  3LKF A;  4U6V A;  4P24 A;  4Q7G A;  3B07 B;  1LKF A;  3B07 A;  3M2L A;  2LKF A;  4J0O A;  3O44 A;  3ROH A;  4H56 A;  3M4E A;  3M3R A;  4IDJ A;  4IYT A;  3ANZ A;  7AHL A;  4P1X B;  4I0N A;  4P1X A;  3M4D A;  4P1Y B;  5K59 C; 
#chains in the Genus database with same CATH topology
 4IYA A;  1T5R A;  4P1Y A;  4YHD A;  2QK7 B;  4TW1 B;  2QK7 A;  1PVL A;  4TW1 A;  4IYC A;  5K59 A;  4IZL A;  2YGT A;  3LKF A;  4U6V A;  4P24 A;  4Q7G A;  3B07 B;  1LKF A;  3B07 A;  3M2L A;  2LKF A;  4J0O A;  3O44 A;  3ROH A;  4H56 A;  3M4E A;  3M3R A;  1XEZ A;  4IDJ A;  4IYT A;  3ANZ A;  7AHL A;  4P1X B;  4I0N A;  4P1X A;  3M4D A;  4P1Y B;  5K59 C; 
#chains in the Genus database with same CATH homology
 4IYA A;  1T5R A;  4P1Y A;  4YHD A;  2QK7 B;  4TW1 B;  2QK7 A;  1PVL A;  4TW1 A;  4IYC A;  5K59 A;  4IZL A;  2YGT A;  3LKF A;  4U6V A;  4P24 A;  4Q7G A;  3B07 B;  1LKF A;  3B07 A;  3M2L A;  2LKF A;  4J0O A;  3O44 A;  3ROH A;  4H56 A;  3M4E A;  3M3R A;  4IDJ A;  4IYT A;  3ANZ A;  7AHL A;  4P1X B;  4I0N A;  4P1X A;  3M4D A;  4P1Y B;  5K59 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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