4P39A

Crystal structure of the human c5ar antagonist c5a-a8
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
69
structure length
69
Chain Sequence
STLQKKIEEIAAKYKHSVVKKCCYDGARVNNDETCEQRAARISLGPRCIKAFTECCVVASQLRANISFK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Immune system
molecule keywords Complement C5
publication title Structural and functional characterization of human and murine C5a anaphylatoxins.
pubmed doi rcsb
source organism Homo sapiens
total genus 23
structure length 69
sequence length 69
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2014-03-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01821 ANATO Anaphylotoxin-like domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.91.20 Mainly Alpha Up-down Bundle Influenza Virus Matrix Protein; Chain A, domain 1 Anaphylotoxins (complement system) 4p39A00
4P3BA 1C5AA 4HWJA 4HW5A 3HQAA 3KLSA 2A73B 1CFAA 4I6OA 4P3AA 4P39A 2B39A 4UU9C 5B4PB 4WB3A 3CU7A 4FXKB 4WB2A 5JPNB 1KJSA 3HQBA
chains in the Genus database with same CATH superfamily
4P3BA 1C5AA 2Z16A 4HWJA 4HW5A 3HQAA 4FXGB 3KLSA 2A73B 1CFAA 4I6OA 4P3AA 3VDXA 4P39A 4D9JA 5JPMB 3MD2A 2B39A 1AA7A 4UU9C 1EA3A 5B4PB 4WB3A 4PUSA 3CU7A 4FXKB 5CQEA 4WB2A 5JPNB 1KJSA 3HQBA 4ITVA 4IQ4A
chains in the Genus database with same CATH topology
4P3BA 1C5AA 4HWJA 4HW5A 3HQAA 3KLSA 2A73B 1CFAA 4I6OA 4P3AA 4P39A 2B39A 4UU9C 5B4PB 4WB3A 3CU7A 4FXKB 4WB2A 5JPNB 1KJSA 3HQBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P3B A;  1C5A A;  4HWJ A;  4HW5 A;  3HQA A;  3KLS A;  2A73 B;  1CFA A;  4I6O A;  4P3A A;  4P39 A;  2B39 A;  4UU9 C;  5B4P B;  4WB3 A;  3CU7 A;  4FXK B;  4WB2 A;  5JPN B;  1KJS A;  3HQB A; 
#chains in the Genus database with same CATH topology
 4P3B A;  1C5A A;  2Z16 A;  4HWJ A;  4HW5 A;  3HQA A;  4FXG B;  3KLS A;  2A73 B;  1CFA A;  4I6O A;  4P3A A;  3VDX A;  4P39 A;  4D9J A;  5JPM B;  3MD2 A;  2B39 A;  1AA7 A;  4UU9 C;  1EA3 A;  5B4P B;  4WB3 A;  4PUS A;  3CU7 A;  4FXK B;  5CQE A;  4WB2 A;  5JPN B;  1KJS A;  3HQB A;  4ITV A;  4IQ4 A; 
#chains in the Genus database with same CATH homology
 4P3B A;  1C5A A;  4HWJ A;  4HW5 A;  3HQA A;  3KLS A;  2A73 B;  1CFA A;  4I6O A;  4P3A A;  4P39 A;  2B39 A;  4UU9 C;  5B4P B;  4WB3 A;  3CU7 A;  4FXK B;  4WB2 A;  5JPN B;  1KJS A;  3HQB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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