4P6TA

Crystal structure of tyrosinase from bacillus megaterium with p-tyrosol in the active site
Total Genus 103
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
103
sequence length
287
structure length
287
Chain Sequence
KYRVRKNVLHLTDTEKRDFVRTVLILKEKGIYDRYIAWHGAAGKFHTPPGSDRNAAHMSSAFLPWHREYLLRFERDLQSINPEVTLPYWEWETDAQMQDPSQSQIWSADFMGGNGNPIKDFIVDTGPFAAGRWTTIDEQGNPSGGLKRNFGATKEAPTLPTRDDVLNALKITQYDTPPWDMTSQNSFRNQLEGFINGPQLHNRVHRWVGGQMGVVPTAPNDPVFFLHHANVDRIWAVWQIIHRNQNYQPMKNGPFGQNFRDPMYPWNTTPEDVMNHRKLGYVYDIEL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Oxidoreductase
molecule keywords Tyrosinase
publication title Determination of tyrosinase substrate-binding modes reveals mechanistic differences between type-3 copper proteins.
pubmed doi rcsb
source organism Bacillus megaterium
total genus 103
structure length 287
sequence length 287
chains with identical sequence B
ec nomenclature ec 1.14.18.1: Tyrosinase.
pdb deposition date 2014-03-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00264 Tyrosinase Common central domain of tyrosinase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1280.10 Mainly Alpha Orthogonal Bundle di-copper center containing domain from catechol oxidase Di-copper center containing domain from catechol oxidase 4p6tA00
2AHLA 4L37A 1LNLA 3NQ1A 3W6WA 3NQ5A 1WX2A 4HD6A 3AWWA 3AWUA 1JS8A 2ZWDA 3GWJA 2ZWEA 2Y9WA 2ZWGA 1HCYA 2Y9XA 4Z0ZA 1BUGA 4OUAB 5I38A 2ZMXA 4YZWA 4L37B 2ZWFA 1WX4A 2ZMZA 1HC1A 4Z10A 1LLAA 3AWYA 4J3PA 2P3XA 3WJMB 3NPYA 3AWVA 4HD7A 4J6VA 3AWXA 4J6UA 3WJMA 1WXCA 4J3QA 1BT1A 4Z0YA 4J6TA 3NTMA 1LL1A 3WKYA 3AWSA 3NM8A 3AWZA 3HHSB 4J3RA 1OXYA 4P6TA 3W6QA 3HHSA 5I3AA 3QJOA 5CE9A 1WX5A 4P6SA 2AHKA 4HD4A 5I3BA 3AWTA 1BT3A 1NOLA 3AX0A 4D87A 3NQ0A 1BT2A 4P6RA 4OUAA 2ZMYA
chains in the Genus database with same CATH superfamily
2AHLA 4L37A 1LNLA 3NQ1A 3W6WA 3NQ5A 1WX2A 4HD6A 3AWWA 3AWUA 1JS8A 2ZWDA 3GWJA 2ZWEA 2Y9WA 2ZWGA 1HCYA 2Y9XA 4Z0ZA 1BUGA 4OUAB 5I38A 2ZMXA 4YZWA 4L37B 2ZWFA 1WX4A 2ZMZA 1HC1A 4Z10A 1LLAA 3AWYA 4J3PA 2P3XA 3WJMB 3NPYA 3AWVA 4HD7A 4J6VA 3AWXA 4J6UA 3WJMA 1WXCA 4J3QA 1BT1A 4Z0YA 4J6TA 3NTMA 1LL1A 3WKYA 3AWSA 3NM8A 3AWZA 3HHSB 4J3RA 1OXYA 4P6TA 3W6QA 3HHSA 5I3AA 3QJOA 5CE9A 1WX5A 4P6SA 2AHKA 4HD4A 5I3BA 3AWTA 1BT3A 1NOLA 3AX0A 4D87A 3NQ0A 1BT2A 4P6RA 4OUAA 2ZMYA
chains in the Genus database with same CATH topology
2AHLA 4L37A 1LNLA 3NQ1A 3W6WA 3NQ5A 1WX2A 4HD6A 3AWWA 3AWUA 1JS8A 2ZWDA 3GWJA 2ZWEA 2Y9WA 2ZWGA 1HCYA 2Y9XA 4Z0ZA 1BUGA 4OUAB 5I38A 2ZMXA 4YZWA 4L37B 2ZWFA 1WX4A 2ZMZA 1HC1A 4Z10A 1LLAA 3AWYA 4J3PA 2P3XA 3WJMB 3NPYA 3AWVA 4HD7A 4J6VA 3AWXA 4J6UA 3WJMA 1WXCA 4J3QA 1BT1A 4Z0YA 4J6TA 3NTMA 1LL1A 3WKYA 3AWSA 3NM8A 3AWZA 3HHSB 4J3RA 1OXYA 4P6TA 3W6QA 3HHSA 5I3AA 3QJOA 5CE9A 1WX5A 4P6SA 2AHKA 4HD4A 5I3BA 3AWTA 1BT3A 1NOLA 3AX0A 4D87A 3NQ0A 1BT2A 4P6RA 4OUAA 2ZMYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AHL A;  4L37 A;  1LNL A;  3NQ1 A;  3W6W A;  3NQ5 A;  1WX2 A;  4HD6 A;  3AWW A;  3AWU A;  1JS8 A;  2ZWD A;  3GWJ A;  2ZWE A;  2Y9W A;  2ZWG A;  1HCY A;  2Y9X A;  4Z0Z A;  1BUG A;  4OUA B;  5I38 A;  2ZMX A;  4YZW A;  4L37 B;  2ZWF A;  1WX4 A;  2ZMZ A;  1HC1 A;  4Z10 A;  1LLA A;  3AWY A;  4J3P A;  2P3X A;  3WJM B;  3NPY A;  3AWV A;  4HD7 A;  4J6V A;  3AWX A;  4J6U A;  3WJM A;  1WXC A;  4J3Q A;  1BT1 A;  4Z0Y A;  4J6T A;  3NTM A;  1LL1 A;  3WKY A;  3AWS A;  3NM8 A;  3AWZ A;  3HHS B;  4J3R A;  1OXY A;  4P6T A;  3W6Q A;  3HHS A;  5I3A A;  3QJO A;  5CE9 A;  1WX5 A;  4P6S A;  2AHK A;  4HD4 A;  5I3B A;  3AWT A;  1BT3 A;  1NOL A;  3AX0 A;  4D87 A;  3NQ0 A;  1BT2 A;  4P6R A;  4OUA A;  2ZMY A; 
#chains in the Genus database with same CATH topology
 2AHL A;  4L37 A;  1LNL A;  3NQ1 A;  3W6W A;  3NQ5 A;  1WX2 A;  4HD6 A;  3AWW A;  3AWU A;  1JS8 A;  2ZWD A;  3GWJ A;  2ZWE A;  2Y9W A;  2ZWG A;  1HCY A;  2Y9X A;  4Z0Z A;  1BUG A;  4OUA B;  5I38 A;  2ZMX A;  4YZW A;  4L37 B;  2ZWF A;  1WX4 A;  2ZMZ A;  1HC1 A;  4Z10 A;  1LLA A;  3AWY A;  4J3P A;  2P3X A;  3WJM B;  3NPY A;  3AWV A;  4HD7 A;  4J6V A;  3AWX A;  4J6U A;  3WJM A;  1WXC A;  4J3Q A;  1BT1 A;  4Z0Y A;  4J6T A;  3NTM A;  1LL1 A;  3WKY A;  3AWS A;  3NM8 A;  3AWZ A;  3HHS B;  4J3R A;  1OXY A;  4P6T A;  3W6Q A;  3HHS A;  5I3A A;  3QJO A;  5CE9 A;  1WX5 A;  4P6S A;  2AHK A;  4HD4 A;  5I3B A;  3AWT A;  1BT3 A;  1NOL A;  3AX0 A;  4D87 A;  3NQ0 A;  1BT2 A;  4P6R A;  4OUA A;  2ZMY A; 
#chains in the Genus database with same CATH homology
 2AHL A;  4L37 A;  1LNL A;  3NQ1 A;  3W6W A;  3NQ5 A;  1WX2 A;  4HD6 A;  3AWW A;  3AWU A;  1JS8 A;  2ZWD A;  3GWJ A;  2ZWE A;  2Y9W A;  2ZWG A;  1HCY A;  2Y9X A;  4Z0Z A;  1BUG A;  4OUA B;  5I38 A;  2ZMX A;  4YZW A;  4L37 B;  2ZWF A;  1WX4 A;  2ZMZ A;  1HC1 A;  4Z10 A;  1LLA A;  3AWY A;  4J3P A;  2P3X A;  3WJM B;  3NPY A;  3AWV A;  4HD7 A;  4J6V A;  3AWX A;  4J6U A;  3WJM A;  1WXC A;  4J3Q A;  1BT1 A;  4Z0Y A;  4J6T A;  3NTM A;  1LL1 A;  3WKY A;  3AWS A;  3NM8 A;  3AWZ A;  3HHS B;  4J3R A;  1OXY A;  4P6T A;  3W6Q A;  3HHS A;  5I3A A;  3QJO A;  5CE9 A;  1WX5 A;  4P6S A;  2AHK A;  4HD4 A;  5I3B A;  3AWT A;  1BT3 A;  1NOL A;  3AX0 A;  4D87 A;  3NQ0 A;  1BT2 A;  4P6R A;  4OUA A;  2ZMY A; 
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