4PNKG

G protein-coupled receptor kinase 2 in complex with gsk180736a
Total Genus 15
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
62
structure length
62
Chain Sequence
ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase/transferase inhibitor
molecule keywords Beta-adrenergic receptor kinase 1
publication title Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors.
pubmed doi rcsb
source organism Homo sapiens
total genus 15
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 2014-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 4pnkG00
4KFMG 5HE3G 5HE2G 1GOTG 1TBGE 3KRWG 3PVWG 5HE0G 2PBIA 1XHMB 3V5WG 3AH8G 5TDHG 1A0RG 3KRXG 1OMWG 5HE1G 4MK0G 2BCJG 1B9YB 3CIKG 2TRCG 4PNKG 1GG2G 1GP2G 1B9XB 3SN6G 5KDOG 3PSCG 3PVUG
chains in the Genus database with same CATH superfamily
4KFMG 5HE3G 5HE2G 1GOTG 1TBGE 3KRWG 3PVWG 5HE0G 2PBIA 1XHMB 3V5WG 3AH8G 5TDHG 1HFES 1A0RG 3KRXG 1OMWG 5HE1G 4MK0G 2BCJG 1B9YB 1IOJA 3CIKG 2TRCG 4PNKG 1GG2G 1GP2G 1B9XB 3SN6G 5KDOG 3PSCG 3PVUG
chains in the Genus database with same CATH topology
4KFMG 5HE3G 5HE2G 1GOTG 1TBGE 3KRWG 3PVWG 5HE0G 2PBIA 1XHMB 3V5WG 3AH8G 5TDHG 1A0RG 3KRXG 1OMWG 5HE1G 4MK0G 2BCJG 1B9YB 3CIKG 2TRCG 4PNKG 1GG2G 1GP2G 1B9XB 3SN6G 5KDOG 3PSCG 3PVUG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KFM G;  5HE3 G;  5HE2 G;  1GOT G;  1TBG E;  3KRW G;  3PVW G;  5HE0 G;  2PBI A;  1XHM B;  3V5W G;  3AH8 G;  5TDH G;  1A0R G;  3KRX G;  1OMW G;  5HE1 G;  4MK0 G;  2BCJ G;  1B9Y B;  3CIK G;  2TRC G;  4PNK G;  1GG2 G;  1GP2 G;  1B9X B;  3SN6 G;  5KDO G;  3PSC G;  3PVU G; 
#chains in the Genus database with same CATH topology
 4KFM G;  5HE3 G;  5HE2 G;  1GOT G;  1TBG E;  3KRW G;  3PVW G;  5HE0 G;  2PBI A;  1XHM B;  3V5W G;  3AH8 G;  5TDH G;  1HFE S;  1A0R G;  3KRX G;  1OMW G;  5HE1 G;  4MK0 G;  2BCJ G;  1B9Y B;  1IOJ A;  3CIK G;  2TRC G;  4PNK G;  1GG2 G;  1GP2 G;  1B9X B;  3SN6 G;  5KDO G;  3PSC G;  3PVU G; 
#chains in the Genus database with same CATH homology
 4KFM G;  5HE3 G;  5HE2 G;  1GOT G;  1TBG E;  3KRW G;  3PVW G;  5HE0 G;  2PBI A;  1XHM B;  3V5W G;  3AH8 G;  5TDH G;  1A0R G;  3KRX G;  1OMW G;  5HE1 G;  4MK0 G;  2BCJ G;  1B9Y B;  3CIK G;  2TRC G;  4PNK G;  1GG2 G;  1GP2 G;  1B9X B;  3SN6 G;  5KDO G;  3PSC G;  3PVU G; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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