4PNKG

G protein-coupled receptor kinase 2 in complex with gsk180736a
Total Genus 15
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
15
sequence length
62
structure length
62
Chain Sequence
ASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Identification and structure-function analysis of subfamily selective g protein-coupled receptor kinase inhibitors.
pubmed doi rcsb
molecule tags Transferase/transferase inhibitor
source organism Homo sapiens
molecule keywords Beta-adrenergic receptor kinase 1
total genus 15
structure length 62
sequence length 62
ec nomenclature
pdb deposition date 2014-05-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
G PF00631 G-gamma GGL domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
4.10.260.10 Few Secondary Structures Irregular G Protein Gi Gamma 2 Transducin (heterotrimeric G protein), gamma chain 4pnkG00
5KDOG 2PBIA 5HE1G 3PVWG 3KRWG 1A0RG 1OMWG 2BCJG 3PVUG 3SN6G 5HE3G 1XHMB 3V5WG 1TBGE 1B9YB 5HE0G 5HE2G 4PNKG 5TDHG 4MK0G 1GG2G 3KRXG 3PSCG 1B9XB 1GP2G 3AH8G 2TRCG 1GOTG 3CIKG 4KFMG
chains in the Genus database with same CATH superfamily
5KDOG 2PBIA 1HFES 5HE1G 3PVWG 3KRWG 1A0RG 1OMWG 2BCJG 3PVUG 3SN6G 5HE3G 1IOJA 1XHMB 3V5WG 1TBGE 1B9YB 5HE0G 5HE2G 4PNKG 5TDHG 4MK0G 1GG2G 3KRXG 3PSCG 1B9XB 1GP2G 3AH8G 2TRCG 1GOTG 3CIKG 4KFMG
chains in the Genus database with same CATH topology
5KDOG 2PBIA 5HE1G 3PVWG 3KRWG 1A0RG 1OMWG 2BCJG 3PVUG 3SN6G 5HE3G 1XHMB 3V5WG 1TBGE 1B9YB 5HE0G 5HE2G 4PNKG 5TDHG 4MK0G 1GG2G 3KRXG 3PSCG 1B9XB 1GP2G 3AH8G 2TRCG 1GOTG 3CIKG 4KFMG
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5KDO G;  2PBI A;  5HE1 G;  3PVW G;  3KRW G;  1A0R G;  1OMW G;  2BCJ G;  3PVU G;  3SN6 G;  5HE3 G;  1XHM B;  3V5W G;  1TBG E;  1B9Y B;  5HE0 G;  5HE2 G;  4PNK G;  5TDH G;  4MK0 G;  1GG2 G;  3KRX G;  3PSC G;  1B9X B;  1GP2 G;  3AH8 G;  2TRC G;  1GOT G;  3CIK G;  4KFM G; 
#chains in the Genus database with same CATH topology
 5KDO G;  2PBI A;  1HFE S;  5HE1 G;  3PVW G;  3KRW G;  1A0R G;  1OMW G;  2BCJ G;  3PVU G;  3SN6 G;  5HE3 G;  1IOJ A;  1XHM B;  3V5W G;  1TBG E;  1B9Y B;  5HE0 G;  5HE2 G;  4PNK G;  5TDH G;  4MK0 G;  1GG2 G;  3KRX G;  3PSC G;  1B9X B;  1GP2 G;  3AH8 G;  2TRC G;  1GOT G;  3CIK G;  4KFM G; 
#chains in the Genus database with same CATH homology
 5KDO G;  2PBI A;  5HE1 G;  3PVW G;  3KRW G;  1A0R G;  1OMW G;  2BCJ G;  3PVU G;  3SN6 G;  5HE3 G;  1XHM B;  3V5W G;  1TBG E;  1B9Y B;  5HE0 G;  5HE2 G;  4PNK G;  5TDH G;  4MK0 G;  1GG2 G;  3KRX G;  3PSC G;  1B9X B;  1GP2 G;  3AH8 G;  2TRC G;  1GOT G;  3CIK G;  4KFM G; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...