4Q3VA

Crystal structure of schistosoma mansoni arginase in complex with inhibitor bec
Total Genus 123
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
123
sequence length
346
structure length
337
Chain Sequence
PKLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQT
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Arginase
publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Hydrolase/hydrolase inhibitor
total genus 123
structure length 337
sequence length 346
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q3vA00
3THHA 1P8OA 1T4SA 5CEVA 2ZAVA 3TH7A 1P8SA 1T4RA 4RHQA 1XFKA 4ITYA 1P8MA 3THEA 1GQ6A 4GSZA 3MJLA 3MFWA 4HXQA 4IE2A 2EF4A 3E6VA 3THJA 1P8NA 4RHKA 1TBLA 2RLAA 4MXRA 3SKKA 3E8QA 1TBHA 1TBJA 4MYNA 4Q40A 3MFVA 4Q3RA 4Q3TA 4GSVA 1HQXA 4CEVA 3LP4A 4IXVA 1R1OA 2CEVA 1CEVA 3MMRA 1P8RA 1P8QA 4IU0A 3E6KA 3M1RA 4RLAA 1WVBA 1D3VA 3TF3A 3LHLA 1HQ5A 3KV2A 3DJ8A 2A0MA 4GSMA 4Q42A 1WVAA 3PZLA 1T5FA 2PHOA 4HZEA 3SL0A 1HQFA 3GN0A 4IXUA 3LP7A 3SL1A 4IU4A 4MYLA 5RLAA 1RLAA 4MYFA 4RHJA 1TA1A 2EF5A 4Q3VA 4G3HA 1HQHA 5HJ9A 4Q41A 2EIVA 4Q3PA 4MYKA 2PHAA 2AEBA 3CEVA 4IE1A 4RHIA 4IU5A 3F80A 4DZ4A 1PQ3A 3E8ZA 1T4PA 1T5GA 4GWCA 3RLAA 1HQGA 2PLLA 3GMZA 4GWDA 3NIOA 4Q3SA 4HWWA 1GQ7A 4RHMA 4IE3A 1ZPGA 4Q3RC 1WOIA 3SJTA 1ZPEA 4Q3QA 3E9BA 4FCKA 4RHLA 5HJAA 1T4TA 4Q3UA 1WOGA 1P8PA 4IU1A 3NIQA 4FCIA 4I06A 1WOHA 3NIPA
chains in the Genus database with same CATH superfamily
3RQDA 3THHA 1P8OA 1T4SA 5EFNA 3EZPA 5EEKA 5CEVA 5G13A 2ZAVA 3TH7A 1P8SA 1T4RA 3F06A 1XFKA 4RHQA 4ITYA 4ZUQA 3MZ3A 1P8MA 3SFHA 3THEA 1GQ6A 4GSZA 3MJLA 3MFWA 4HXQA 4IE2A 3F0RA 2EF4A 3E6VA 3THJA 4CBTA 1P8NA 4RHKA 3EW8A 5EEFA 2VQQA 1TBLA 2RLAA 4CBYA 3MAXA 4MXRA 5FCWA 3ZNSA 3SKKA 3E8QA 1TBHA 3EWFA 1TBJA 4MYNA 4Q40A 2VQWG 1T64A 3MFVA 4BZ7A 3EZTA 5EFHA 5DC8A 4Q3RA 4Q3TA 5DC5A 4GSVA 1HQXA 4CEVA 3LP4A 4IXVA 5A2SA 1R1OA 2CEVA 3C0ZA 4QA0A 1C3RA 5EEIA 1CEVA 3MMRA 1T69A 1P8RA 1P8QA 4IU0A 3E6KA 3M1RA 5EEMA 1T67A 3MZ4A 4RLAA 1WVBA 5BWZA 1D3VA 3TF3A 5EF8A 4QA7A 3LHLA 5D1BA 4BZ6A 3MENA 4QA3A 1HQ5A 4QA4A 5G0IA 3KV2A 5EF7A 5G1CA 4QA2A 3DJ8A 5G3WA 5DC7A 2A0MA 4BKXB 4GSMA 5D1CA 4Q42A 5G0JA 1WVAA 3PZLA 1T5FA 2PHOA 3MZ6A 5EFKB 4HZEA 3SL0A 1HQFA 3GN0A 3MZ7A 1W22A 3LP7A 1C3PA 4IU4A 4IXUA 4MYLA 5G1BA 1RLAA 5RLAA 4MYFA 5THUA 5LI3A 4RHJA 1TA1A 2EF5A 4Q3VA 4G3HA 1HQHA 5HJ9A 1ZZ1A 4Q41A 2EIVA 4Q3PA 1C3SA 2V5XA 4MYKA 2PHAA 2AEBA 3CEVA 4IE1A 1ZZ3A 4RHIA 4RN1A 4IU5A 3F80A 4A69A 3C0YA 5G10A 4DZ4A 2VQJA 1PQ3A 4BZ5A 4LY1A 3E8ZA 4QA6A 4ZUPA 5G0XA 1T4PA 2VQVA 5G12A 1T5GA 4GWCA 4ZUNA 3RLAA 1HQGA 2PLLA 3GMZA 4GWDA 5THSA 3NIOA 3C10A 4Q3SA 4BZ9A 5ICNB 5G0YA 5EENA 4HWWA 4ZUOA 5G11A 1GQ7A 2VQMA 4QA1A 4RHMA 5EFBD 5G17A 3SL1A 5IX0A 4IE3A 1VKGA 5D1DA 4BZ8A 1ZPGA 4Q3RC 1WOIA 4QA5A 2VCGA 3SFFA 3SJTA 3ZNRA 5G0HA 1ZPEA 4LXZA 2GH6A 3Q9EA 4Q3QA 2V5WA 3E9BA 5FUEA 5G1AA 4FCKA 4RHLA 5DC6A 5IWGA 5HJAA 5THTA 1ZZ0A 3Q9FA 1T4TA 4Q3UA 3F07A 1WOGA 4CQFA 2VQOA 5EFGA 1P8PA 4IU1A 5EFJD 3NIQA 5G0GA 4RN0A 4FCIA 4RN2A 5THVA 5JI5A 4I06A 3Q9BA 4ZUMA 4ZURA 3Q9CA 1WOHA 3NIPA
chains in the Genus database with same CATH topology
3THHA 1P8OA 1T4SA 5CEVA 2ZAVA 3TH7A 1P8SA 1T4RA 4RHQA 1XFKA 4ITYA 1P8MA 3THEA 1GQ6A 4GSZA 3MJLA 3MFWA 4HXQA 4IE2A 2EF4A 3E6VA 3THJA 1P8NA 4RHKA 1TBLA 2RLAA 4MXRA 3SKKA 3E8QA 1TBHA 1TBJA 4MYNA 4Q40A 3MFVA 4Q3RA 4Q3TA 4GSVA 1HQXA 4CEVA 3LP4A 4IXVA 1R1OA 2CEVA 1CEVA 3MMRA 1P8RA 1P8QA 4IU0A 3E6KA 3M1RA 4RLAA 1WVBA 1D3VA 3TF3A 3LHLA 1HQ5A 3KV2A 3DJ8A 2A0MA 4GSMA 4Q42A 1WVAA 3PZLA 1T5FA 2PHOA 4HZEA 3SL0A 1HQFA 3GN0A 4IXUA 3LP7A 3SL1A 4IU4A 4MYLA 5RLAA 1RLAA 4MYFA 4RHJA 1TA1A 2EF5A 4Q3VA 4G3HA 1HQHA 5HJ9A 4Q41A 2EIVA 4Q3PA 4MYKA 2PHAA 2AEBA 3CEVA 4IE1A 4RHIA 4IU5A 3F80A 4DZ4A 1PQ3A 3E8ZA 1T4PA 1T5GA 4GWCA 3RLAA 1HQGA 2PLLA 3GMZA 4GWDA 3NIOA 4Q3SA 4HWWA 1GQ7A 4RHMA 4IE3A 1ZPGA 4Q3RC 1WOIA 3SJTA 1ZPEA 4Q3QA 3E9BA 4FCKA 4RHLA 5HJAA 1T4TA 4Q3UA 1WOGA 1P8PA 4IU1A 3NIQA 4FCIA 4I06A 1WOHA 3NIPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3THH A;  1P8O A;  1T4S A;  5CEV A;  2ZAV A;  3TH7 A;  1P8S A;  1T4R A;  4RHQ A;  1XFK A;  4ITY A;  1P8M A;  3THE A;  1GQ6 A;  4GSZ A;  3MJL A;  3MFW A;  4HXQ A;  4IE2 A;  2EF4 A;  3E6V A;  3THJ A;  1P8N A;  4RHK A;  1TBL A;  2RLA A;  4MXR A;  3SKK A;  3E8Q A;  1TBH A;  1TBJ A;  4MYN A;  4Q40 A;  3MFV A;  4Q3R A;  4Q3T A;  4GSV A;  1HQX A;  4CEV A;  3LP4 A;  4IXV A;  1R1O A;  2CEV A;  1CEV A;  3MMR A;  1P8R A;  1P8Q A;  4IU0 A;  3E6K A;  3M1R A;  4RLA A;  1WVB A;  1D3V A;  3TF3 A;  3LHL A;  1HQ5 A;  3KV2 A;  3DJ8 A;  2A0M A;  4GSM A;  4Q42 A;  1WVA A;  3PZL A;  1T5F A;  2PHO A;  4HZE A;  3SL0 A;  1HQF A;  3GN0 A;  4IXU A;  3LP7 A;  3SL1 A;  4IU4 A;  4MYL A;  5RLA A;  1RLA A;  4MYF A;  4RHJ A;  1TA1 A;  2EF5 A;  4Q3V A;  4G3H A;  1HQH A;  5HJ9 A;  4Q41 A;  2EIV A;  4Q3P A;  4MYK A;  2PHA A;  2AEB A;  3CEV A;  4IE1 A;  4RHI A;  4IU5 A;  3F80 A;  4DZ4 A;  1PQ3 A;  3E8Z A;  1T4P A;  1T5G A;  4GWC A;  3RLA A;  1HQG A;  2PLL A;  3GMZ A;  4GWD A;  3NIO A;  4Q3S A;  4HWW A;  1GQ7 A;  4RHM A;  4IE3 A;  1ZPG A;  4Q3R C;  1WOI A;  3SJT A;  1ZPE A;  4Q3Q A;  3E9B A;  4FCK A;  4RHL A;  5HJA A;  1T4T A;  4Q3U A;  1WOG A;  1P8P A;  4IU1 A;  3NIQ A;  4FCI A;  4I06 A;  1WOH A;  3NIP A; 
#chains in the Genus database with same CATH topology
 3RQD A;  3THH A;  1P8O A;  1T4S A;  5EFN A;  3EZP A;  5EEK A;  5CEV A;  5G13 A;  2ZAV A;  3TH7 A;  1P8S A;  1T4R A;  3F06 A;  1XFK A;  4RHQ A;  4ITY A;  4ZUQ A;  3MZ3 A;  1P8M A;  3SFH A;  3THE A;  1GQ6 A;  4GSZ A;  3MJL A;  3MFW A;  4HXQ A;  4IE2 A;  3F0R A;  2EF4 A;  3E6V A;  3THJ A;  4CBT A;  1P8N A;  4RHK A;  3EW8 A;  5EEF A;  2VQQ A;  1TBL A;  2RLA A;  4CBY A;  3MAX A;  4MXR A;  5FCW A;  3ZNS A;  3SKK A;  3E8Q A;  1TBH A;  3EWF A;  1TBJ A;  4MYN A;  4Q40 A;  2VQW G;  1T64 A;  3MFV A;  4BZ7 A;  3EZT A;  5EFH A;  5DC8 A;  4Q3R A;  4Q3T A;  5DC5 A;  4GSV A;  1HQX A;  4CEV A;  3LP4 A;  4IXV A;  5A2S A;  1R1O A;  2CEV A;  3C0Z A;  4QA0 A;  1C3R A;  5EEI A;  1CEV A;  3MMR A;  1T69 A;  1P8R A;  1P8Q A;  4IU0 A;  3E6K A;  3M1R A;  5EEM A;  1T67 A;  3MZ4 A;  4RLA A;  1WVB A;  5BWZ A;  1D3V A;  3TF3 A;  5EF8 A;  4QA7 A;  3LHL A;  5D1B A;  4BZ6 A;  3MEN A;  4QA3 A;  1HQ5 A;  4QA4 A;  5G0I A;  3KV2 A;  5EF7 A;  5G1C A;  4QA2 A;  3DJ8 A;  5G3W A;  5DC7 A;  2A0M A;  4BKX B;  4GSM A;  5D1C A;  4Q42 A;  5G0J A;  1WVA A;  3PZL A;  1T5F A;  2PHO A;  3MZ6 A;  5EFK B;  4HZE A;  3SL0 A;  1HQF A;  3GN0 A;  3MZ7 A;  1W22 A;  3LP7 A;  1C3P A;  4IU4 A;  4IXU A;  4MYL A;  5G1B A;  1RLA A;  5RLA A;  4MYF A;  5THU A;  5LI3 A;  4RHJ A;  1TA1 A;  2EF5 A;  4Q3V A;  4G3H A;  1HQH A;  5HJ9 A;  1ZZ1 A;  4Q41 A;  2EIV A;  4Q3P A;  1C3S A;  2V5X A;  4MYK A;  2PHA A;  2AEB A;  3CEV A;  4IE1 A;  1ZZ3 A;  4RHI A;  4RN1 A;  4IU5 A;  3F80 A;  4A69 A;  3C0Y A;  5G10 A;  4DZ4 A;  2VQJ A;  1PQ3 A;  4BZ5 A;  4LY1 A;  3E8Z A;  4QA6 A;  4ZUP A;  5G0X A;  1T4P A;  2VQV A;  5G12 A;  1T5G A;  4GWC A;  4ZUN A;  3RLA A;  1HQG A;  2PLL A;  3GMZ A;  4GWD A;  5THS A;  3NIO A;  3C10 A;  4Q3S A;  4BZ9 A;  5ICN B;  5G0Y A;  5EEN A;  4HWW A;  4ZUO A;  5G11 A;  1GQ7 A;  2VQM A;  4QA1 A;  4RHM A;  5EFB D;  5G17 A;  3SL1 A;  5IX0 A;  4IE3 A;  1VKG A;  5D1D A;  4BZ8 A;  1ZPG A;  4Q3R C;  1WOI A;  4QA5 A;  2VCG A;  3SFF A;  3SJT A;  3ZNR A;  5G0H A;  1ZPE A;  4LXZ A;  2GH6 A;  3Q9E A;  4Q3Q A;  2V5W A;  3E9B A;  5FUE A;  5G1A A;  4FCK A;  4RHL A;  5DC6 A;  5IWG A;  5HJA A;  5THT A;  1ZZ0 A;  3Q9F A;  1T4T A;  4Q3U A;  3F07 A;  1WOG A;  4CQF A;  2VQO A;  5EFG A;  1P8P A;  4IU1 A;  5EFJ D;  3NIQ A;  5G0G A;  4RN0 A;  4FCI A;  4RN2 A;  5THV A;  5JI5 A;  4I06 A;  3Q9B A;  4ZUM A;  4ZUR A;  3Q9C A;  1WOH A;  3NIP A; 
#chains in the Genus database with same CATH homology
 3THH A;  1P8O A;  1T4S A;  5CEV A;  2ZAV A;  3TH7 A;  1P8S A;  1T4R A;  4RHQ A;  1XFK A;  4ITY A;  1P8M A;  3THE A;  1GQ6 A;  4GSZ A;  3MJL A;  3MFW A;  4HXQ A;  4IE2 A;  2EF4 A;  3E6V A;  3THJ A;  1P8N A;  4RHK A;  1TBL A;  2RLA A;  4MXR A;  3SKK A;  3E8Q A;  1TBH A;  1TBJ A;  4MYN A;  4Q40 A;  3MFV A;  4Q3R A;  4Q3T A;  4GSV A;  1HQX A;  4CEV A;  3LP4 A;  4IXV A;  1R1O A;  2CEV A;  1CEV A;  3MMR A;  1P8R A;  1P8Q A;  4IU0 A;  3E6K A;  3M1R A;  4RLA A;  1WVB A;  1D3V A;  3TF3 A;  3LHL A;  1HQ5 A;  3KV2 A;  3DJ8 A;  2A0M A;  4GSM A;  4Q42 A;  1WVA A;  3PZL A;  1T5F A;  2PHO A;  4HZE A;  3SL0 A;  1HQF A;  3GN0 A;  4IXU A;  3LP7 A;  3SL1 A;  4IU4 A;  4MYL A;  5RLA A;  1RLA A;  4MYF A;  4RHJ A;  1TA1 A;  2EF5 A;  4Q3V A;  4G3H A;  1HQH A;  5HJ9 A;  4Q41 A;  2EIV A;  4Q3P A;  4MYK A;  2PHA A;  2AEB A;  3CEV A;  4IE1 A;  4RHI A;  4IU5 A;  3F80 A;  4DZ4 A;  1PQ3 A;  3E8Z A;  1T4P A;  1T5G A;  4GWC A;  3RLA A;  1HQG A;  2PLL A;  3GMZ A;  4GWD A;  3NIO A;  4Q3S A;  4HWW A;  1GQ7 A;  4RHM A;  4IE3 A;  1ZPG A;  4Q3R C;  1WOI A;  3SJT A;  1ZPE A;  4Q3Q A;  3E9B A;  4FCK A;  4RHL A;  5HJA A;  1T4T A;  4Q3U A;  1WOG A;  1P8P A;  4IU1 A;  3NIQ A;  4FCI A;  4I06 A;  1WOH A;  3NIP A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...