4Q40A

Crystal structure of schistosoma mansoni arginase in complex with l-valine
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
344
structure length
335
Chain Sequence
KLLYTSANFLGIPTNRGQPKIGTYQGPELIRKSNFFQLVAEDGIQLTDCGDIIPVELNEAEDPQRFGMKWSRSFSLTTLRIAERVEELMKQSNKSTPLVIVGGDHSMATGTILGHAEAKPDLCVLWIDAHGDINTPLNSASGNMHGMPLSFLVKELQDQIPWLDDFEGIKPCLNASNIAYIGLRDLDAHETHDIRKHGIAYFTMLDVDRMGIEAVIKEALLAVNPRLEKAIHLSFDIDALDPLVAPSTGTAVPGGLTLREGLRICEEVSATGKLSVVELAELNPLLGSQEDVLKTQSSAVHILRACLGHCRSGHLPFKVRNLTDQGIMSRAAHMQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Arginase
publication title Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis.
pubmed doi rcsb
source organism Schistosoma mansoni
molecule tags Hydrolase
total genus 132
structure length 335
sequence length 344
chains with identical sequence B, C, D
ec nomenclature ec 3.5.3.1: Arginase.
pdb deposition date 2014-04-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00491 Arginase Arginase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.800.10 Alpha Beta 3-Layer(aba) Sandwich Arginase; Chain A Ureohydrolase domain 4q40A00
2ZAVA 1RLAA 3MFVA 4GSVA 1P8SA 2EF4A 4GSZA 4Q40A 1P8MA 4FCIA 3THEA 4IXVA 4MXRA 1PQ3A 2PHAA 2PLLA 4GSMA 4IU1A 3MMRA 4IXUA 4RHLA 4G3HA 3DJ8A 1P8PA 1TBLA 3RLAA 1ZPGA 3MFWA 1HQ5A 1WVAA 1XFKA 2CEVA 3KV2A 4Q3QA 3M1RA 1CEVA 4IE3A 4Q3RC 4MYKA 4MYFA 1P8NA 3GN0A 5RLAA 4IU0A 1WOGA 4DZ4A 3E9BA 4Q3VA 1GQ7A 3E6VA 1TA1A 4Q3TA 4HZEA 1T4RA 3PZLA 1R1OA 4IU4A 1HQXA 3SJTA 1T5GA 1T4SA 4Q41A 1T5FA 1HQHA 1ZPEA 3LP4A 3THJA 4Q3SA 4IE1A 3TH7A 4RHKA 3F80A 1P8OA 4CEVA 3E6KA 4MYLA 3NIPA 3E8ZA 1HQGA 4GWDA 1WOHA 3LP7A 4IE2A 1TBHA 3SL0A 4IU5A 5HJAA 3E8QA 2PHOA 3MJLA 3NIQA 4Q3RA 4FCKA 3NIOA 5CEVA 4HXQA 3SKKA 2AEBA 4Q3PA 4RHQA 1D3VA 1HQFA 1T4PA 1P8RA 1TBJA 2A0MA 2RLAA 4RHMA 3GMZA 4RHJA 3CEVA 2EF5A 1P8QA 4Q3UA 1T4TA 4I06A 4Q42A 5HJ9A 4MYNA 3SL1A 4RHIA 3TF3A 1WOIA 4RLAA 4ITYA 4GWCA 1WVBA 1GQ6A 2EIVA 3LHLA 4HWWA 3THHA
chains in the Genus database with same CATH superfamily
3C0ZA 5FUEA 5IWGA 4CBYA 2ZAVA 1RLAA 3MFVA 4GSVA 4ZUMA 4BZ5A 1P8SA 3C0YA 2EF4A 5G13A 5IX0A 4BZ7A 4GSZA 4Q40A 1P8MA 4FCIA 4ZUNA 3THEA 3Q9BA 4IXVA 4MXRA 4QA0A 3Q9FA 4QA6A 1PQ3A 4QA1A 2PHAA 2PLLA 4GSMA 4IU1A 4ZUOA 3MMRA 4IXUA 5D1DA 4RHLA 5DC7A 5DC6A 4G3HA 3DJ8A 4RN1A 5EEIA 5G1CA 1P8PA 4BKXB 3EZPA 1T67A 1TBLA 3RLAA 1ZPGA 1ZZ0A 3MFWA 5G17A 1HQ5A 5THUA 5EENA 4ZURA 5EEKA 1WVAA 5G12A 2GH6A 1XFKA 2CEVA 2VQQA 5EFGA 5A2SA 3MZ7A 5EFNA 3KV2A 4Q3QA 5D1CA 2VQOA 3M1RA 3RQDA 4BZ6A 1CEVA 2V5XA 4IE3A 4MYKA 2VQJA 1P8NA 3GN0A 4MYFA 4Q3RC 4IU0A 5RLAA 1WOGA 4DZ4A 3E9BA 4Q3VA 5G0XA 1GQ7A 3E6VA 1TA1A 3MAXA 4Q3TA 4HZEA 5THSA 1T4RA 3PZLA 5EFBD 5EFKB 1R1OA 2VQWG 5JI5A 4IU4A 1HQXA 4QA3A 5EEMA 3SJTA 4RN2A 1T5GA 2VQMA 1T4SA 4Q41A 1T5FA 4LY1A 1HQHA 1ZZ3A 4LXZA 1ZPEA 3LP4A 3THJA 4RN0A 5G11A 3C10A 2V5WA 4Q3SA 4IE1A 3TH7A 4RHKA 3F80A 4QA7A 5ICNB 1W22A 5EFHA 1P8OA 4CEVA 3E6KA 4MYLA 3NIPA 2VCGA 5G0HA 3MENA 3E8ZA 1HQGA 1ZZ1A 5D1BA 5G1AA 4GWDA 5G0IA 1T69A 5LI3A 1WOHA 3LP7A 5THTA 3EWFA 4IE2A 1TBHA 3SL0A 3SFHA 4IU5A 5FCWA 5HJAA 3ZNSA 3MZ6A 1C3RA 3E8QA 2PHOA 3Q9CA 5G0GA 3MJLA 3NIQA 4Q3RA 5G0YA 4BZ8A 4FCKA 5DC8A 3EZTA 3NIOA 4ZUQA 5THVA 4HXQA 3SKKA 5CEVA 2AEBA 4QA4A 4Q3PA 4RHQA 5EF8A 1D3VA 1HQFA 1T4PA 1P8RA 4CBTA 1T64A 4A69A 5DC5A 1TBJA 2A0MA 2RLAA 3F06A 4RHMA 3ZNRA 3GMZA 4RHJA 5G1BA 3CEVA 4CQFA 2EF5A 5EF7A 1C3PA 1P8QA 3MZ3A 4Q3UA 4BZ9A 1T4TA 4I06A 3MZ4A 4QA5A 3Q9EA 4ZUPA 1C3SA 3SFFA 4Q42A 3F07A 5HJ9A 4MYNA 5G3WA 4QA2A 5G0JA 3SL1A 4RHIA 3TF3A 3EW8A 1WOIA 4RLAA 5G10A 4ITYA 4GWCA 5EEFA 5EFJD 1WVBA 5BWZA 1GQ6A 1VKGA 2EIVA 3LHLA 2VQVA 3F0RA 4HWWA 3THHA
chains in the Genus database with same CATH topology
2ZAVA 1RLAA 3MFVA 4GSVA 1P8SA 2EF4A 4GSZA 4Q40A 1P8MA 4FCIA 3THEA 4IXVA 4MXRA 1PQ3A 2PHAA 2PLLA 4GSMA 4IU1A 3MMRA 4IXUA 4RHLA 4G3HA 3DJ8A 1P8PA 1TBLA 3RLAA 1ZPGA 3MFWA 1HQ5A 1WVAA 1XFKA 2CEVA 3KV2A 4Q3QA 3M1RA 1CEVA 4IE3A 4Q3RC 4MYKA 4MYFA 1P8NA 3GN0A 5RLAA 4IU0A 1WOGA 4DZ4A 3E9BA 4Q3VA 1GQ7A 3E6VA 1TA1A 4Q3TA 4HZEA 1T4RA 3PZLA 1R1OA 4IU4A 1HQXA 3SJTA 1T5GA 1T4SA 4Q41A 1T5FA 1HQHA 1ZPEA 3LP4A 3THJA 4Q3SA 4IE1A 3TH7A 4RHKA 3F80A 1P8OA 4CEVA 3E6KA 4MYLA 3NIPA 3E8ZA 1HQGA 4GWDA 1WOHA 3LP7A 4IE2A 1TBHA 3SL0A 4IU5A 5HJAA 3E8QA 2PHOA 3MJLA 3NIQA 4Q3RA 4FCKA 3NIOA 5CEVA 4HXQA 3SKKA 2AEBA 4Q3PA 4RHQA 1D3VA 1HQFA 1T4PA 1P8RA 1TBJA 2A0MA 2RLAA 4RHMA 3GMZA 4RHJA 3CEVA 2EF5A 1P8QA 4Q3UA 1T4TA 4I06A 4Q42A 5HJ9A 4MYNA 3SL1A 4RHIA 3TF3A 1WOIA 4RLAA 4ITYA 4GWCA 1WVBA 1GQ6A 2EIVA 3LHLA 4HWWA 3THHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZAV A;  1RLA A;  3MFV A;  4GSV A;  1P8S A;  2EF4 A;  4GSZ A;  4Q40 A;  1P8M A;  4FCI A;  3THE A;  4IXV A;  4MXR A;  1PQ3 A;  2PHA A;  2PLL A;  4GSM A;  4IU1 A;  3MMR A;  4IXU A;  4RHL A;  4G3H A;  3DJ8 A;  1P8P A;  1TBL A;  3RLA A;  1ZPG A;  3MFW A;  1HQ5 A;  1WVA A;  1XFK A;  2CEV A;  3KV2 A;  4Q3Q A;  3M1R A;  1CEV A;  4IE3 A;  4Q3R C;  4MYK A;  4MYF A;  1P8N A;  3GN0 A;  5RLA A;  4IU0 A;  1WOG A;  4DZ4 A;  3E9B A;  4Q3V A;  1GQ7 A;  3E6V A;  1TA1 A;  4Q3T A;  4HZE A;  1T4R A;  3PZL A;  1R1O A;  4IU4 A;  1HQX A;  3SJT A;  1T5G A;  1T4S A;  4Q41 A;  1T5F A;  1HQH A;  1ZPE A;  3LP4 A;  3THJ A;  4Q3S A;  4IE1 A;  3TH7 A;  4RHK A;  3F80 A;  1P8O A;  4CEV A;  3E6K A;  4MYL A;  3NIP A;  3E8Z A;  1HQG A;  4GWD A;  1WOH A;  3LP7 A;  4IE2 A;  1TBH A;  3SL0 A;  4IU5 A;  5HJA A;  3E8Q A;  2PHO A;  3MJL A;  3NIQ A;  4Q3R A;  4FCK A;  3NIO A;  5CEV A;  4HXQ A;  3SKK A;  2AEB A;  4Q3P A;  4RHQ A;  1D3V A;  1HQF A;  1T4P A;  1P8R A;  1TBJ A;  2A0M A;  2RLA A;  4RHM A;  3GMZ A;  4RHJ A;  3CEV A;  2EF5 A;  1P8Q A;  4Q3U A;  1T4T A;  4I06 A;  4Q42 A;  5HJ9 A;  4MYN A;  3SL1 A;  4RHI A;  3TF3 A;  1WOI A;  4RLA A;  4ITY A;  4GWC A;  1WVB A;  1GQ6 A;  2EIV A;  3LHL A;  4HWW A;  3THH A; 
#chains in the Genus database with same CATH topology
 3C0Z A;  5FUE A;  5IWG A;  4CBY A;  2ZAV A;  1RLA A;  3MFV A;  4GSV A;  4ZUM A;  4BZ5 A;  1P8S A;  3C0Y A;  2EF4 A;  5G13 A;  5IX0 A;  4BZ7 A;  4GSZ A;  4Q40 A;  1P8M A;  4FCI A;  4ZUN A;  3THE A;  3Q9B A;  4IXV A;  4MXR A;  4QA0 A;  3Q9F A;  4QA6 A;  1PQ3 A;  4QA1 A;  2PHA A;  2PLL A;  4GSM A;  4IU1 A;  4ZUO A;  3MMR A;  4IXU A;  5D1D A;  4RHL A;  5DC7 A;  5DC6 A;  4G3H A;  3DJ8 A;  4RN1 A;  5EEI A;  5G1C A;  1P8P A;  4BKX B;  3EZP A;  1T67 A;  1TBL A;  3RLA A;  1ZPG A;  1ZZ0 A;  3MFW A;  5G17 A;  1HQ5 A;  5THU A;  5EEN A;  4ZUR A;  5EEK A;  1WVA A;  5G12 A;  2GH6 A;  1XFK A;  2CEV A;  2VQQ A;  5EFG A;  5A2S A;  3MZ7 A;  5EFN A;  3KV2 A;  4Q3Q A;  5D1C A;  2VQO A;  3M1R A;  3RQD A;  4BZ6 A;  1CEV A;  2V5X A;  4IE3 A;  4MYK A;  2VQJ A;  1P8N A;  3GN0 A;  4MYF A;  4Q3R C;  4IU0 A;  5RLA A;  1WOG A;  4DZ4 A;  3E9B A;  4Q3V A;  5G0X A;  1GQ7 A;  3E6V A;  1TA1 A;  3MAX A;  4Q3T A;  4HZE A;  5THS A;  1T4R A;  3PZL A;  5EFB D;  5EFK B;  1R1O A;  2VQW G;  5JI5 A;  4IU4 A;  1HQX A;  4QA3 A;  5EEM A;  3SJT A;  4RN2 A;  1T5G A;  2VQM A;  1T4S A;  4Q41 A;  1T5F A;  4LY1 A;  1HQH A;  1ZZ3 A;  4LXZ A;  1ZPE A;  3LP4 A;  3THJ A;  4RN0 A;  5G11 A;  3C10 A;  2V5W A;  4Q3S A;  4IE1 A;  3TH7 A;  4RHK A;  3F80 A;  4QA7 A;  5ICN B;  1W22 A;  5EFH A;  1P8O A;  4CEV A;  3E6K A;  4MYL A;  3NIP A;  2VCG A;  5G0H A;  3MEN A;  3E8Z A;  1HQG A;  1ZZ1 A;  5D1B A;  5G1A A;  4GWD A;  5G0I A;  1T69 A;  5LI3 A;  1WOH A;  3LP7 A;  5THT A;  3EWF A;  4IE2 A;  1TBH A;  3SL0 A;  3SFH A;  4IU5 A;  5FCW A;  5HJA A;  3ZNS A;  3MZ6 A;  1C3R A;  3E8Q A;  2PHO A;  3Q9C A;  5G0G A;  3MJL A;  3NIQ A;  4Q3R A;  5G0Y A;  4BZ8 A;  4FCK A;  5DC8 A;  3EZT A;  3NIO A;  4ZUQ A;  5THV A;  4HXQ A;  3SKK A;  5CEV A;  2AEB A;  4QA4 A;  4Q3P A;  4RHQ A;  5EF8 A;  1D3V A;  1HQF A;  1T4P A;  1P8R A;  4CBT A;  1T64 A;  4A69 A;  5DC5 A;  1TBJ A;  2A0M A;  2RLA A;  3F06 A;  4RHM A;  3ZNR A;  3GMZ A;  4RHJ A;  5G1B A;  3CEV A;  4CQF A;  2EF5 A;  5EF7 A;  1C3P A;  1P8Q A;  3MZ3 A;  4Q3U A;  4BZ9 A;  1T4T A;  4I06 A;  3MZ4 A;  4QA5 A;  3Q9E A;  4ZUP A;  1C3S A;  3SFF A;  4Q42 A;  3F07 A;  5HJ9 A;  4MYN A;  5G3W A;  4QA2 A;  5G0J A;  3SL1 A;  4RHI A;  3TF3 A;  3EW8 A;  1WOI A;  4RLA A;  5G10 A;  4ITY A;  4GWC A;  5EEF A;  5EFJ D;  1WVB A;  5BWZ A;  1GQ6 A;  1VKG A;  2EIV A;  3LHL A;  2VQV A;  3F0R A;  4HWW A;  3THH A; 
#chains in the Genus database with same CATH homology
 2ZAV A;  1RLA A;  3MFV A;  4GSV A;  1P8S A;  2EF4 A;  4GSZ A;  4Q40 A;  1P8M A;  4FCI A;  3THE A;  4IXV A;  4MXR A;  1PQ3 A;  2PHA A;  2PLL A;  4GSM A;  4IU1 A;  3MMR A;  4IXU A;  4RHL A;  4G3H A;  3DJ8 A;  1P8P A;  1TBL A;  3RLA A;  1ZPG A;  3MFW A;  1HQ5 A;  1WVA A;  1XFK A;  2CEV A;  3KV2 A;  4Q3Q A;  3M1R A;  1CEV A;  4IE3 A;  4Q3R C;  4MYK A;  4MYF A;  1P8N A;  3GN0 A;  5RLA A;  4IU0 A;  1WOG A;  4DZ4 A;  3E9B A;  4Q3V A;  1GQ7 A;  3E6V A;  1TA1 A;  4Q3T A;  4HZE A;  1T4R A;  3PZL A;  1R1O A;  4IU4 A;  1HQX A;  3SJT A;  1T5G A;  1T4S A;  4Q41 A;  1T5F A;  1HQH A;  1ZPE A;  3LP4 A;  3THJ A;  4Q3S A;  4IE1 A;  3TH7 A;  4RHK A;  3F80 A;  1P8O A;  4CEV A;  3E6K A;  4MYL A;  3NIP A;  3E8Z A;  1HQG A;  4GWD A;  1WOH A;  3LP7 A;  4IE2 A;  1TBH A;  3SL0 A;  4IU5 A;  5HJA A;  3E8Q A;  2PHO A;  3MJL A;  3NIQ A;  4Q3R A;  4FCK A;  3NIO A;  5CEV A;  4HXQ A;  3SKK A;  2AEB A;  4Q3P A;  4RHQ A;  1D3V A;  1HQF A;  1T4P A;  1P8R A;  1TBJ A;  2A0M A;  2RLA A;  4RHM A;  3GMZ A;  4RHJ A;  3CEV A;  2EF5 A;  1P8Q A;  4Q3U A;  1T4T A;  4I06 A;  4Q42 A;  5HJ9 A;  4MYN A;  3SL1 A;  4RHI A;  3TF3 A;  1WOI A;  4RLA A;  4ITY A;  4GWC A;  1WVB A;  1GQ6 A;  2EIV A;  3LHL A;  4HWW A;  3THH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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