4QBEA

The second sphere residue t263 is important for function and activity of ptp1b through modulating wpd loop
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
298
structure length
298
Chain Sequence
MEMEKEFEQIDKSGSWAAIYQDIRHEASDFPCRVAKLPKNKNRNRYRDVSPFDHSRIKLHQEDNDYINASLIKMEEAQRSYILTQGPLPNTCGHFWEMVWEQKSRGVVMLNRVMEKGSLKCAQYWPQKEEKEMIFEDTNLKLTLISEDIKSYYTVRQLELENLTTQETREILHFHYTTWPDFGVPESPASFLNFLFKVRESGSLSPEHGPVVVHCSAGIGRSGTFCLADTCLLLMDKRKDPSSVDIKKVLLEMRKFRMGLIQSADQLRFSYLAVIEGAKFIMGDSSVQDQWKELSHED
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The second-sphere residue T263 is important for the function and catalytic activity of PTP1B via interaction with the WPD-loop
pubmed doi rcsb
molecule tags Hydrolase
source organism Homo sapiens
molecule keywords Tyrosine-protein phosphatase non-receptor type 1
total genus 97
structure length 298
sequence length 298
ec nomenclature ec 3.1.3.48: Protein-tyrosine-phosphatase.
pdb deposition date 2014-05-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00102 Y_phosphatase Protein-tyrosine phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4qbeA00
1JLNA 1C85A 5KACA 3BLUA 1LARA 4OHDA 2CNEA 1OEVA 1PA1A 1PTUA 1Q6MA 4QAHA 5IBSA 2A3KA 4RKKA 1XXPA 4GRYA 1RPMA 1P15A 4GFVA 4OHEA 5KA3A 2QBQA 1XRIA 2J17A 1OEUA 1YTSA 5EHPA 5M43A 1OHCA 2CMAA 4NNDA 1XXVA 1WRMA 1X24A 1PA9A 2B3OA 2VEXA 2I1YA 1OHEA 1G7FA 4ZRTA 2MBCA 2Y96A 3NMEA 4OHLA 3ZMQA 3EAXA 2BZLA 5BZXA 3AWFA 1MKPA 4R0SA 2H04A 1ZC0A 4WOHA 2PT0A 4QBWA 4B04A 3U96A 4OHIA 4BPCA 3N0AA 2I3UA 3S4OA 1G1GA 2BGDA 2VEUA 3I7ZA 2RF6A 5K22A 1XBOA 3A5KA 2QDCA 2F6YA 1T4JA 4D3PA 3O4SA 5K9VA 2PI7A 4Y2EA 2CM3A 4GWFA 2OUDA 1Q6TA 1WCHA 3EU0A 4GS0A 4QBEA 2QCTA 1Q6NA 1YPTA 1FQ1A 2HY3A 3LJ8A 4NX8A 3AWGA 4J51A 5K25A 2F46A 2H4KA 1ZZWA 5K24A 5KAAA 1NWLA 4D3QA 2CM2A 2F71A 2GP0A 1Q6SA 2G59A 2WGPA 2HXPA 2PA5A 4RH5A 5KABA 3OLRA 5MMZB 2JJDA 4D3RA 1I9TA 3ZM3A 2E0TA 3M4UA 5KA9A 5K23A 2B07A 1EEOA 3S4EA 3QCHA 1NO6A 2CM8A 2Q05A 1U25A 2I6JA 3QCDA 2P4DA 3F81A 3MMJA 4WU3A 2FJNA 2YDUA 2NV5A 3H2XA 4ZN5A 5KA4A 2DXPA 4HJPA 1D5RA 2GWOA 3ZMPA 2F6VA 2VEVA 4WTYA 2CJZA 3CWEA 3D44A 4BJOA 2VEWA 2HCMA 1KAKA 4HJQA 3S3EA 2CMCA 4GRZA 1OETA 3D1OA 2PSZA 2NT2A 1EENA 2QEPA 4AZ1A 2J16B 2H4GA 1U24A 3O4UA 1C84A 2B4SA 2I6PA 3GXGA 1T49A 3MOZA 4Y14A 4QUMA 1YTNA 1RXDA 1PXHA 3D42A 1Q6PA 4ERCA 4I8NA 4RH9A 1NZ7A 3ZV2A 2I4EA 1QXKA 5KADA 2B4UA 1C88A 2PBNA 3V0GA 1ECVA 1GFYA 5KA1A 2OOQA 1ZCLA 1YN9A 3F41A 2I6MA 4S0GA 2C46A 3S3HA 4GE6A 1OHDA 4R30A 3QCKA 2HC1A 2ESBA 2GJTA 3S3FA 3ZM1A 4JMJA 3AWEA 4JMKA 1J4XA 4GFUA 1NWEA 3QCMA 2QBSA 3D1HA 4OHHA 2QBRA 1SUGA 1G7GA 5HDEA 2J16A 2HVLA 5BUGA 3O4TA 1BZCA 1FPZA 1V3AA 1I57A 1U26A 2CNHA 4PYHA 2I75A 5BX1A 2HC2A 2H02A 3A5JA 1PH0A 3SMEA 2Y2FA 3D9CA 2OZ5A 1ONYA 2G6ZA 1PYNA 2I6IA 3EB1A 1Q1MA 2B4PA 5BZZA 3BRHA 4H1OA 1LQFA 1YGUA 3SR9A 4TVVA 3RGQA 2F6TA 2IMGA 1FPRA 3QCJA 3PS5A 2CMBA 2QDMA 2AZRA 2HNQA 1C86A 3QKPA 1OESA 1YFOA 2Q47A 1WAXA 2FJMA 4QAPA 3QCIA 1BZHA 2CNFA 3QCCA 2VEYA 4RHGA 1ZCKA 2NTAA 2CM7A 3O3LA 2CNGA 2PQ5A 3S3KA 1YZ4A 2QBPA 4KYRA 4R0TA 2R0BA 4JBCA 2BGEA 2I6OA 3QCFA 3F9AA 4H34A 4KI9A 3CM3A 2BIJA 3GXHA 1G1FA 4WU2A 4MBBA 4RI4A 1BZJA 2BV5A 3I36A 2F70A 4GE5A 2F6WA 1NL9A 1Q6JA 1QZ0A 2I42A 1KAVA 2I3RA 5EHRA 1PTTA 4DGPA 2HNPA 4ZI4A 1OEOX 4IKCA 5IBMA 1NNYA 3QCBA 5I6VA 2B4OA 1G4US 1PTYA 2CNIA 3B7OA 2QCJA 2QDPA 3EMUA 1PTVA 4HRFA 2NZ6A 2FH7A 2ZN7A 1L8KA 3EZZA 1G1HA 4GE2A 1C87A 2OC3A 2I4HA 1I9SA 1YTWA 2A8BA 3MOWA 1A5YA 1YGRA 4RDDA 1R6HA 2P6XA 4NWGA 2F6FA 3BM8A 1VHRA 5KA0A 4DGXA 2H03A 3RO1A 3O5XA 2ZMMA 3V0DA 4NWFA 3RGOA 3V0JA 1C83A 3ZM0A 3BLTA 5K9WA 1M3GA 3F9BA 2C7SA 3QCNA 2CFVA 2H4VA 5KA7A 4YAAA 5LXQB 2AHSA 1OEMX 4YR8B 3F99A 4NYHA 1YWFA 2I5XA 2SHPA 3QCEA 1LYVA 3QCGA 2B49A 3OMHA 2I4GA 5AWXA 3D1QA 3ZM2A 2HB1A 5J8RA 2NLKA 3V0IA 3QKQA 4ICZA 3V0HA 2M3VA 3QCLA 4QUNA 5KA8A 2F6ZA 3RZ2A 4RI5A 3V0FA 5GTJA 2NT7A 3V0EA 1JF7A 4KYQA 4Z6BA 1ONZA 3I80A 1T48A 1XM2A 4PVGA 1AAXA 1GWZA 4JNBA 1L8GA 5KA2A 1G4WR
chains in the Genus database with same CATH superfamily
1JLNA 1C85A 2Y67A 5KACA 3BLUA 1LARA 4OHDA 2CNEA 1OEVA 1PA1A 1PTUA 1FGSA 1Q6MA 4QAHA 2GC6A 5IBSA 2A3KA 4RKKA 1XXPA 4GRYA 1RPMA 1P15A 5A5FA 4GFVA 4OHEA 5KA3A 2QBQA 1XRIA 2J17A 1OEUA 2GC5A 1W7KA 1YTSA 2JFHA 5EHPA 5M43A 3MVNA 1OHCA 2CMAA 4NNDA 1XXVA 1GQYA 1WRMA 1X24A 1PA9A 2B3OA 4C13A 2VEXA 4BUCA 2I1YA 1OHEA 1G7FA 4ZRTA 2MBCA 2Y96A 3NMEA 4OHLA 3ZMQA 3EAXA 2BZLA 5BZXA 2XPCA 3AWFA 1MKPA 4R0SA 2H04A 1ZC0A 4WOHA 2PT0A 4QBWA 4B04A 3U96A 4OHIA 4BPCA 3N0AA 2I3UA 3S4OA 1G1GA 2BGDA 2VEUA 3I7ZA 2RF6A 5K22A 1XBOA 3A5KA 2QDCA 2F6YA 1T4JA 4D3PA 3O4SA 1JBVA 5K9VA 3N2AA 2PI7A 4Y2EA 2VORA 2CM3A 4GWFA 2OUDA 1Q6TA 1WCHA 3EU0A 4GS0A 4QBEA 1EEHA 2QCTA 1Q6NA 1YPTA 1FQ1A 2HY3A 3LJ8A 2XJAA 4NX8A 3AWGA 4J51A 3PYZA 5K25A 2F46A 2H4KA 1ZZWA 5K24A 5KAAA 1NWLA 4D3QA 2CM2A 2F71A 2GP0A 1Q6SA 4BUBA 2G59A 2WGPA 2HXPA 2PA5A 4RH5A 5KABA 3OLRA 5MMZB 2JJDA 4D3RA 1I9TA 3ZM3A 2E0TA 3M4UA 4QDIA 5KA9A 5K23A 2AM1A 2B07A 1EEOA 3S4EA 3QCHA 1NO6A 2CM8A 2Q05A 1U25A 2JFGA 2I6JA 3QCDA 2P4DA 3ZM6A 3F81A 3MMJA 4WU3A 1GQQA 2FJNA 2YDUA 2NV5A 3H2XA 4ZN5A 5KA4A 2DXPA 4HJPA 1D5RA 2GWOA 2JFFA 3ZMPA 2F6VA 2VEVA 4WTYA 2CJZA 3CWEA 3D44A 4BJOA 1GG4A 2VEWA 2HCMA 1KAKA 4HJQA 3S3EA 2CMCA 4GRZA 1OETA 3D1OA 2PSZA 2NT2A 1EENA 2QEPA 4AZ1A 2J16B 2H4GA 1U24A 3O4UA 1C84A 2B4SA 4UAGA 2I6PA 3GXGA 1T49A 4CVLA 3MOZA 4Y14A 4QUMA 1YTNA 1RXDA 1PXHA 3D42A 1Q6PA 4ERCA 4I8NA 2F00A 4RH9A 1NZ7A 3ZV2A 2I4EA 1QXKA 5KADA 2B4UA 3QCZA 1C88A 1P31A 2PBNA 3V0GA 1ECVA 1GFYA 5KA1A 2OOQA 1ZCLA 1YN9A 3F41A 2I6MA 4S0GA 2C46A 3S3HA 4GE6A 1OHDA 4R30A 3QCKA 2HC1A 2ESBA 2VTEA 2GJTA 2AM2A 3S3FA 3ZM1A 4JMJA 3AWEA 4JMKA 1J4XA 4GFUA 1NWEA 3QCMA 2QBSA 3D1HA 4OHHA 2QBRA 1SUGA 1G7GA 5HDEA 2J16A 3LK7A 2HVLA 5BUGA 3O4TA 1BZCA 1FPZA 1V3AA 1I57A 1U26A 2CNHA 4PYHA 2I75A 5BX1A 2HC2A 2H02A 3A5JA 1PH0A 3SMEA 2Y2FA 3D9CA 1P3DA 2OZ5A 1ONYA 2G6ZA 1PYNA 2I6IA 3UAGA 3EB1A 3HN7A 1Q1MA 1O5ZA 2B4PA 5BZZA 3BRHA 4H1OA 2Y68A 1LQFA 1YGUA 3SR9A 4TVVA 3RGQA 2F6TA 2IMGA 1FPRA 3QCJA 3PS5A 2CMBA 2QDMA 2AZRA 2HNQA 1C86A 3QKPA 1OESA 2Y66A 1YFOA 2Q47A 1WAXA 2FJMA 4QAPA 3QCIA 1BZHA 2CNFA 3QCCA 2VEYA 4RHGA 4ZIYA 1ZCKA 2NTAA 2CM7A 3O3LA 2CNGA 2PQ5A 3S3KA 1YZ4A 2QBPA 4KYRA 4R0TA 2R0BA 4JBCA 2BGEA 2I6OA 3QCFA 3F9AA 4H34A 4KI9A 3CM3A 2BIJA 2VOSA 1E8CA 2GCAA 3GXHA 1G1FA 1W78A 4WU2A 4QF5A 4MBBA 4RI4A 1BZJA 2BV5A 3I36A 2F70A 4GE5A 2F6WA 1JBWA 2X5OA 1NL9A 1Q6JA 1QZ0A 2I42A 1KAVA 2I3RA 5EHRA 4CVKA 1PTTA 2UAGA 4DGPA 2VTDA 2HNPA 4ZI4A 1OEOX 4IKCA 5A5EA 5IBMA 1NNYA 3QCBA 5I6VA 2B4OA 1G4US 1PTYA 2CNIA 2WJPA 3B7OA 2QCJA 2QDPA 3EMUA 1PTVA 4HRFA 2NZ6A 2FH7A 2ZN7A 1L8KA 3EZZA 1G1HA 4GE2A 1C87A 2OC3A 2I4HA 1E0DA 1I9SA 1YTWA 2WTZA 2A8BA 3MOWA 1A5YA 1YGRA 4HV4A 2GCBA 4RDDA 1R6HA 2P6XA 4C12A 4NWGA 2F6FA 3ZL8A 3BM8A 1VHRA 5KA0A 4DGXA 2H03A 3RO1A 3O5XA 2ZMMA 3V0DA 4NWFA 3RGOA 3V0JA 1C83A 2UUPA 3ZM0A 3BLTA 5K9WA 1M3GA 3F9BA 2C7SA 3QCNA 2CFVA 2H4VA 5KA7A 4YAAA 5LXQB 2AHSA 1OEMX 4YR8B 3F99A 4NYHA 1YWFA 2I5XA 2SHPA 3QCEA 1LYVA 3QCGA 4CVMA 3ZM5A 2B49A 3OMHA 2I4GA 5AWXA 3D1QA 3ZM2A 2HB1A 5J8RA 2NLKA 3V0IA 3QKQA 1J6UA 4ICZA 3V0HA 2M3VA 3QCLA 4QUNA 5KA8A 2F6ZA 3RZ2A 4RI5A 3NRSA 3V0FA 5GTJA 2NT7A 3V0EA 2Y1OA 1JF7A 4KYQA 4Z6BA 1ONZA 3I80A 1UAGA 1T48A 1XM2A 4PVGA 1AAXA 1GWZA 2UUOA 4JNBA 1L8GA 5KA2A 1G4WR
chains in the Genus database with same CATH topology
1JLNA 1C85A 5KACA 3BLUA 1LARA 4OHDA 2CNEA 1OEVA 1PA1A 1PTUA 1Q6MA 4QAHA 5IBSA 2A3KA 4RKKA 1XXPA 4GRYA 1RPMA 1P15A 4GFVA 4OHEA 5KA3A 2QBQA 1XRIA 2J17A 1OEUA 1YTSA 5EHPA 5M43A 1OHCA 2CMAA 4NNDA 1XXVA 1WRMA 1X24A 1PA9A 2B3OA 2VEXA 2I1YA 1OHEA 1G7FA 4ZRTA 2MBCA 2Y96A 3NMEA 4OHLA 3ZMQA 3EAXA 2BZLA 5BZXA 3AWFA 1MKPA 4R0SA 2H04A 1ZC0A 4WOHA 2PT0A 4QBWA 4B04A 3U96A 4OHIA 4BPCA 3N0AA 2I3UA 3S4OA 1G1GA 2BGDA 2VEUA 3I7ZA 2RF6A 5K22A 1XBOA 3A5KA 2QDCA 2F6YA 1T4JA 4D3PA 3O4SA 5K9VA 2PI7A 4Y2EA 2CM3A 4GWFA 2OUDA 1Q6TA 1WCHA 3EU0A 4GS0A 4QBEA 2QCTA 1Q6NA 1YPTA 1FQ1A 2HY3A 3LJ8A 4NX8A 3AWGA 4J51A 5K25A 2F46A 2H4KA 1ZZWA 5K24A 5KAAA 1NWLA 4D3QA 2CM2A 2F71A 2GP0A 1Q6SA 2G59A 2WGPA 2HXPA 2PA5A 4RH5A 5KABA 3OLRA 5MMZB 2JJDA 4D3RA 1I9TA 3ZM3A 2E0TA 3M4UA 5KA9A 5K23A 2B07A 1EEOA 3S4EA 3QCHA 1NO6A 2CM8A 2Q05A 1U25A 2I6JA 3QCDA 2P4DA 3F81A 3MMJA 4WU3A 2FJNA 2YDUA 2NV5A 3H2XA 4ZN5A 5KA4A 2DXPA 4HJPA 1D5RA 2GWOA 3ZMPA 2F6VA 2VEVA 4WTYA 2CJZA 3CWEA 3D44A 4BJOA 2VEWA 2HCMA 1KAKA 4HJQA 3S3EA 2CMCA 4GRZA 1OETA 3D1OA 2PSZA 2NT2A 1EENA 2QEPA 4AZ1A 2J16B 2H4GA 1U24A 3O4UA 1C84A 2B4SA 2I6PA 3GXGA 1T49A 3MOZA 4Y14A 4QUMA 1YTNA 1RXDA 1PXHA 3D42A 1Q6PA 4ERCA 4I8NA 4RH9A 1NZ7A 3ZV2A 2I4EA 1QXKA 5KADA 2B4UA 1C88A 2PBNA 3V0GA 1ECVA 1GFYA 5KA1A 2OOQA 1ZCLA 1YN9A 3F41A 2I6MA 4S0GA 2C46A 3S3HA 4GE6A 1OHDA 4R30A 3QCKA 2HC1A 2ESBA 2GJTA 3S3FA 3ZM1A 4JMJA 3AWEA 4JMKA 1J4XA 4GFUA 1NWEA 3QCMA 2QBSA 3D1HA 4OHHA 2QBRA 1SUGA 1G7GA 5HDEA 2J16A 2HVLA 5BUGA 3O4TA 1BZCA 1FPZA 1V3AA 1I57A 1U26A 2CNHA 4PYHA 2I75A 5BX1A 2HC2A 2H02A 3A5JA 1PH0A 3SMEA 2Y2FA 3D9CA 2OZ5A 1ONYA 2G6ZA 1PYNA 2I6IA 3EB1A 1Q1MA 2B4PA 5BZZA 3BRHA 4H1OA 1LQFA 1YGUA 3SR9A 4TVVA 3RGQA 2F6TA 2IMGA 1FPRA 3QCJA 3PS5A 2CMBA 2QDMA 2AZRA 2HNQA 1C86A 3QKPA 1OESA 1YFOA 2Q47A 1WAXA 2FJMA 4QAPA 3QCIA 1BZHA 2CNFA 3QCCA 2VEYA 4RHGA 1ZCKA 2NTAA 2CM7A 3O3LA 2CNGA 2PQ5A 3S3KA 1YZ4A 2QBPA 4KYRA 4R0TA 2R0BA 4JBCA 2BGEA 2I6OA 3QCFA 3F9AA 4H34A 4KI9A 3CM3A 2BIJA 3GXHA 1G1FA 4WU2A 4MBBA 4RI4A 1BZJA 2BV5A 3I36A 2F70A 4GE5A 2F6WA 1NL9A 1Q6JA 1QZ0A 2I42A 1KAVA 2I3RA 5EHRA 1PTTA 4DGPA 2HNPA 4ZI4A 1OEOX 4IKCA 5IBMA 1NNYA 3QCBA 5I6VA 2B4OA 1G4US 1PTYA 2CNIA 3B7OA 2QCJA 2QDPA 3EMUA 1PTVA 4HRFA 2NZ6A 2FH7A 2ZN7A 1L8KA 3EZZA 1G1HA 4GE2A 1C87A 2OC3A 2I4HA 1I9SA 1YTWA 2A8BA 3MOWA 1A5YA 1YGRA 4RDDA 1R6HA 2P6XA 4NWGA 2F6FA 3BM8A 1VHRA 5KA0A 4DGXA 2H03A 3RO1A 3O5XA 2ZMMA 3V0DA 4NWFA 3RGOA 3V0JA 1C83A 3ZM0A 3BLTA 5K9WA 1M3GA 3F9BA 2C7SA 3QCNA 2CFVA 2H4VA 5KA7A 4YAAA 5LXQB 2AHSA 1OEMX 4YR8B 3F99A 4NYHA 1YWFA 2I5XA 2SHPA 3QCEA 1LYVA 3QCGA 2B49A 3OMHA 2I4GA 5AWXA 3D1QA 3ZM2A 2HB1A 5J8RA 2NLKA 3V0IA 3QKQA 4ICZA 3V0HA 2M3VA 3QCLA 4QUNA 5KA8A 2F6ZA 3RZ2A 4RI5A 3V0FA 5GTJA 2NT7A 3V0EA 1JF7A 4KYQA 4Z6BA 1ONZA 3I80A 1T48A 1XM2A 4PVGA 1AAXA 1GWZA 4JNBA 1L8GA 5KA2A 1G4WR
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JLN A;  1C85 A;  5KAC A;  3BLU A;  1LAR A;  4OHD A;  2CNE A;  1OEV A;  1PA1 A;  1PTU A;  1Q6M A;  4QAH A;  5IBS A;  2A3K A;  4RKK A;  1XXP A;  4GRY A;  1RPM A;  1P15 A;  4GFV A;  4OHE A;  5KA3 A;  2QBQ A;  1XRI A;  2J17 A;  1OEU A;  1YTS A;  5EHP A;  5M43 A;  1OHC A;  2CMA A;  4NND A;  1XXV A;  1WRM A;  1X24 A;  1PA9 A;  2B3O A;  2VEX A;  2I1Y A;  1OHE A;  1G7F A;  4ZRT A;  2MBC A;  2Y96 A;  3NME A;  4OHL A;  3ZMQ A;  3EAX A;  2BZL A;  5BZX A;  3AWF A;  1MKP A;  4R0S A;  2H04 A;  1ZC0 A;  4WOH A;  2PT0 A;  4QBW A;  4B04 A;  3U96 A;  4OHI A;  4BPC A;  3N0A A;  2I3U A;  3S4O A;  1G1G A;  2BGD A;  2VEU A;  3I7Z A;  2RF6 A;  5K22 A;  1XBO A;  3A5K A;  2QDC A;  2F6Y A;  1T4J A;  4D3P A;  3O4S A;  5K9V A;  2PI7 A;  4Y2E A;  2CM3 A;  4GWF A;  2OUD A;  1Q6T A;  1WCH A;  3EU0 A;  4GS0 A;  4QBE A;  2QCT A;  1Q6N A;  1YPT A;  1FQ1 A;  2HY3 A;  3LJ8 A;  4NX8 A;  3AWG A;  4J51 A;  5K25 A;  2F46 A;  2H4K A;  1ZZW A;  5K24 A;  5KAA A;  1NWL A;  4D3Q A;  2CM2 A;  2F71 A;  2GP0 A;  1Q6S A;  2G59 A;  2WGP A;  2HXP A;  2PA5 A;  4RH5 A;  5KAB A;  3OLR A;  5MMZ B;  2JJD A;  4D3R A;  1I9T A;  3ZM3 A;  2E0T A;  3M4U A;  5KA9 A;  5K23 A;  2B07 A;  1EEO A;  3S4E A;  3QCH A;  1NO6 A;  2CM8 A;  2Q05 A;  1U25 A;  2I6J A;  3QCD A;  2P4D A;  3F81 A;  3MMJ A;  4WU3 A;  2FJN A;  2YDU A;  2NV5 A;  3H2X A;  4ZN5 A;  5KA4 A;  2DXP A;  4HJP A;  1D5R A;  2GWO A;  3ZMP A;  2F6V A;  2VEV A;  4WTY A;  2CJZ A;  3CWE A;  3D44 A;  4BJO A;  2VEW A;  2HCM A;  1KAK A;  4HJQ A;  3S3E A;  2CMC A;  4GRZ A;  1OET A;  3D1O A;  2PSZ A;  2NT2 A;  1EEN A;  2QEP A;  4AZ1 A;  2J16 B;  2H4G A;  1U24 A;  3O4U A;  1C84 A;  2B4S A;  2I6P A;  3GXG A;  1T49 A;  3MOZ A;  4Y14 A;  4QUM A;  1YTN A;  1RXD A;  1PXH A;  3D42 A;  1Q6P A;  4ERC A;  4I8N A;  4RH9 A;  1NZ7 A;  3ZV2 A;  2I4E A;  1QXK A;  5KAD A;  2B4U A;  1C88 A;  2PBN A;  3V0G A;  1ECV A;  1GFY A;  5KA1 A;  2OOQ A;  1ZCL A;  1YN9 A;  3F41 A;  2I6M A;  4S0G A;  2C46 A;  3S3H A;  4GE6 A;  1OHD A;  4R30 A;  3QCK A;  2HC1 A;  2ESB A;  2GJT A;  3S3F A;  3ZM1 A;  4JMJ A;  3AWE A;  4JMK A;  1J4X A;  4GFU A;  1NWE A;  3QCM A;  2QBS A;  3D1H A;  4OHH A;  2QBR A;  1SUG A;  1G7G A;  5HDE A;  2J16 A;  2HVL A;  5BUG A;  3O4T A;  1BZC A;  1FPZ A;  1V3A A;  1I57 A;  1U26 A;  2CNH A;  4PYH A;  2I75 A;  5BX1 A;  2HC2 A;  2H02 A;  3A5J A;  1PH0 A;  3SME A;  2Y2F A;  3D9C A;  2OZ5 A;  1ONY A;  2G6Z A;  1PYN A;  2I6I A;  3EB1 A;  1Q1M A;  2B4P A;  5BZZ A;  3BRH A;  4H1O A;  1LQF A;  1YGU A;  3SR9 A;  4TVV A;  3RGQ A;  2F6T A;  2IMG A;  1FPR A;  3QCJ A;  3PS5 A;  2CMB A;  2QDM A;  2AZR A;  2HNQ A;  1C86 A;  3QKP A;  1OES A;  1YFO A;  2Q47 A;  1WAX A;  2FJM A;  4QAP A;  3QCI A;  1BZH A;  2CNF A;  3QCC A;  2VEY A;  4RHG A;  1ZCK A;  2NTA A;  2CM7 A;  3O3L A;  2CNG A;  2PQ5 A;  3S3K A;  1YZ4 A;  2QBP A;  4KYR A;  4R0T A;  2R0B A;  4JBC A;  2BGE A;  2I6O A;  3QCF A;  3F9A A;  4H34 A;  4KI9 A;  3CM3 A;  2BIJ A;  3GXH A;  1G1F A;  4WU2 A;  4MBB A;  4RI4 A;  1BZJ A;  2BV5 A;  3I36 A;  2F70 A;  4GE5 A;  2F6W A;  1NL9 A;  1Q6J A;  1QZ0 A;  2I42 A;  1KAV A;  2I3R A;  5EHR A;  1PTT A;  4DGP A;  2HNP A;  4ZI4 A;  1OEO X;  4IKC A;  5IBM A;  1NNY A;  3QCB A;  5I6V A;  2B4O A;  1G4U S;  1PTY A;  2CNI A;  3B7O A;  2QCJ A;  2QDP A;  3EMU A;  1PTV A;  4HRF A;  2NZ6 A;  2FH7 A;  2ZN7 A;  1L8K A;  3EZZ A;  1G1H A;  4GE2 A;  1C87 A;  2OC3 A;  2I4H A;  1I9S A;  1YTW A;  2A8B A;  3MOW A;  1A5Y A;  1YGR A;  4RDD A;  1R6H A;  2P6X A;  4NWG A;  2F6F A;  3BM8 A;  1VHR A;  5KA0 A;  4DGX A;  2H03 A;  3RO1 A;  3O5X A;  2ZMM A;  3V0D A;  4NWF A;  3RGO A;  3V0J A;  1C83 A;  3ZM0 A;  3BLT A;  5K9W A;  1M3G A;  3F9B A;  2C7S A;  3QCN A;  2CFV A;  2H4V A;  5KA7 A;  4YAA A;  5LXQ B;  2AHS A;  1OEM X;  4YR8 B;  3F99 A;  4NYH A;  1YWF A;  2I5X A;  2SHP A;  3QCE A;  1LYV A;  3QCG A;  2B49 A;  3OMH A;  2I4G A;  5AWX A;  3D1Q A;  3ZM2 A;  2HB1 A;  5J8R A;  2NLK A;  3V0I A;  3QKQ A;  4ICZ A;  3V0H A;  2M3V A;  3QCL A;  4QUN A;  5KA8 A;  2F6Z A;  3RZ2 A;  4RI5 A;  3V0F A;  5GTJ A;  2NT7 A;  3V0E A;  1JF7 A;  4KYQ A;  4Z6B A;  1ONZ A;  3I80 A;  1T48 A;  1XM2 A;  4PVG A;  1AAX A;  1GWZ A;  4JNB A;  1L8G A;  5KA2 A;  1G4W R; 
#chains in the Genus database with same CATH topology
 1JLN A;  1C85 A;  2Y67 A;  5KAC A;  3BLU A;  1LAR A;  4OHD A;  2CNE A;  1OEV A;  1PA1 A;  1PTU A;  1FGS A;  1Q6M A;  4QAH A;  2GC6 A;  5IBS A;  2A3K A;  4RKK A;  1XXP A;  4GRY A;  1RPM A;  1P15 A;  5A5F A;  4GFV A;  4OHE A;  5KA3 A;  2QBQ A;  1XRI A;  2J17 A;  1OEU A;  2GC5 A;  1W7K A;  1YTS A;  2JFH A;  5EHP A;  5M43 A;  3MVN A;  1OHC A;  2CMA A;  4NND A;  1XXV A;  1GQY A;  1WRM A;  1X24 A;  1PA9 A;  2B3O A;  4C13 A;  2VEX A;  4BUC A;  2I1Y A;  1OHE A;  1G7F A;  4ZRT A;  2MBC A;  2Y96 A;  3NME A;  4OHL A;  3ZMQ A;  3EAX A;  2BZL A;  5BZX A;  2XPC A;  3AWF A;  1MKP A;  4R0S A;  2H04 A;  1ZC0 A;  4WOH A;  2PT0 A;  4QBW A;  4B04 A;  3U96 A;  4OHI A;  4BPC A;  3N0A A;  2I3U A;  3S4O A;  1G1G A;  2BGD A;  2VEU A;  3I7Z A;  2RF6 A;  5K22 A;  1XBO A;  3A5K A;  2QDC A;  2F6Y A;  1T4J A;  4D3P A;  3O4S A;  1JBV A;  5K9V A;  3N2A A;  2PI7 A;  4Y2E A;  2VOR A;  2CM3 A;  4GWF A;  2OUD A;  1Q6T A;  1WCH A;  3EU0 A;  4GS0 A;  4QBE A;  1EEH A;  2QCT A;  1Q6N A;  1YPT A;  1FQ1 A;  2HY3 A;  3LJ8 A;  2XJA A;  4NX8 A;  3AWG A;  4J51 A;  3PYZ A;  5K25 A;  2F46 A;  2H4K A;  1ZZW A;  5K24 A;  5KAA A;  1NWL A;  4D3Q A;  2CM2 A;  2F71 A;  2GP0 A;  1Q6S A;  4BUB A;  2G59 A;  2WGP A;  2HXP A;  2PA5 A;  4RH5 A;  5KAB A;  3OLR A;  5MMZ B;  2JJD A;  4D3R A;  1I9T A;  3ZM3 A;  2E0T A;  3M4U A;  4QDI A;  5KA9 A;  5K23 A;  2AM1 A;  2B07 A;  1EEO A;  3S4E A;  3QCH A;  1NO6 A;  2CM8 A;  2Q05 A;  1U25 A;  2JFG A;  2I6J A;  3QCD A;  2P4D A;  3ZM6 A;  3F81 A;  3MMJ A;  4WU3 A;  1GQQ A;  2FJN A;  2YDU A;  2NV5 A;  3H2X A;  4ZN5 A;  5KA4 A;  2DXP A;  4HJP A;  1D5R A;  2GWO A;  2JFF A;  3ZMP A;  2F6V A;  2VEV A;  4WTY A;  2CJZ A;  3CWE A;  3D44 A;  4BJO A;  1GG4 A;  2VEW A;  2HCM A;  1KAK A;  4HJQ A;  3S3E A;  2CMC A;  4GRZ A;  1OET A;  3D1O A;  2PSZ A;  2NT2 A;  1EEN A;  2QEP A;  4AZ1 A;  2J16 B;  2H4G A;  1U24 A;  3O4U A;  1C84 A;  2B4S A;  4UAG A;  2I6P A;  3GXG A;  1T49 A;  4CVL A;  3MOZ A;  4Y14 A;  4QUM A;  1YTN A;  1RXD A;  1PXH A;  3D42 A;  1Q6P A;  4ERC A;  4I8N A;  2F00 A;  4RH9 A;  1NZ7 A;  3ZV2 A;  2I4E A;  1QXK A;  5KAD A;  2B4U A;  3QCZ A;  1C88 A;  1P31 A;  2PBN A;  3V0G A;  1ECV A;  1GFY A;  5KA1 A;  2OOQ A;  1ZCL A;  1YN9 A;  3F41 A;  2I6M A;  4S0G A;  2C46 A;  3S3H A;  4GE6 A;  1OHD A;  4R30 A;  3QCK A;  2HC1 A;  2ESB A;  2VTE A;  2GJT A;  2AM2 A;  3S3F A;  3ZM1 A;  4JMJ A;  3AWE A;  4JMK A;  1J4X A;  4GFU A;  1NWE A;  3QCM A;  2QBS A;  3D1H A;  4OHH A;  2QBR A;  1SUG A;  1G7G A;  5HDE A;  2J16 A;  3LK7 A;  2HVL A;  5BUG A;  3O4T A;  1BZC A;  1FPZ A;  1V3A A;  1I57 A;  1U26 A;  2CNH A;  4PYH A;  2I75 A;  5BX1 A;  2HC2 A;  2H02 A;  3A5J A;  1PH0 A;  3SME A;  2Y2F A;  3D9C A;  1P3D A;  2OZ5 A;  1ONY A;  2G6Z A;  1PYN A;  2I6I A;  3UAG A;  3EB1 A;  3HN7 A;  1Q1M A;  1O5Z A;  2B4P A;  5BZZ A;  3BRH A;  4H1O A;  2Y68 A;  1LQF A;  1YGU A;  3SR9 A;  4TVV A;  3RGQ A;  2F6T A;  2IMG A;  1FPR A;  3QCJ A;  3PS5 A;  2CMB A;  2QDM A;  2AZR A;  2HNQ A;  1C86 A;  3QKP A;  1OES A;  2Y66 A;  1YFO A;  2Q47 A;  1WAX A;  2FJM A;  4QAP A;  3QCI A;  1BZH A;  2CNF A;  3QCC A;  2VEY A;  4RHG A;  4ZIY A;  1ZCK A;  2NTA A;  2CM7 A;  3O3L A;  2CNG A;  2PQ5 A;  3S3K A;  1YZ4 A;  2QBP A;  4KYR A;  4R0T A;  2R0B A;  4JBC A;  2BGE A;  2I6O A;  3QCF A;  3F9A A;  4H34 A;  4KI9 A;  3CM3 A;  2BIJ A;  2VOS A;  1E8C A;  2GCA A;  3GXH A;  1G1F A;  1W78 A;  4WU2 A;  4QF5 A;  4MBB A;  4RI4 A;  1BZJ A;  2BV5 A;  3I36 A;  2F70 A;  4GE5 A;  2F6W A;  1JBW A;  2X5O A;  1NL9 A;  1Q6J A;  1QZ0 A;  2I42 A;  1KAV A;  2I3R A;  5EHR A;  4CVK A;  1PTT A;  2UAG A;  4DGP A;  2VTD A;  2HNP A;  4ZI4 A;  1OEO X;  4IKC A;  5A5E A;  5IBM A;  1NNY A;  3QCB A;  5I6V A;  2B4O A;  1G4U S;  1PTY A;  2CNI A;  2WJP A;  3B7O A;  2QCJ A;  2QDP A;  3EMU A;  1PTV A;  4HRF A;  2NZ6 A;  2FH7 A;  2ZN7 A;  1L8K A;  3EZZ A;  1G1H A;  4GE2 A;  1C87 A;  2OC3 A;  2I4H A;  1E0D A;  1I9S A;  1YTW A;  2WTZ A;  2A8B A;  3MOW A;  1A5Y A;  1YGR A;  4HV4 A;  2GCB A;  4RDD A;  1R6H A;  2P6X A;  4C12 A;  4NWG A;  2F6F A;  3ZL8 A;  3BM8 A;  1VHR A;  5KA0 A;  4DGX A;  2H03 A;  3RO1 A;  3O5X A;  2ZMM A;  3V0D A;  4NWF A;  3RGO A;  3V0J A;  1C83 A;  2UUP A;  3ZM0 A;  3BLT A;  5K9W A;  1M3G A;  3F9B A;  2C7S A;  3QCN A;  2CFV A;  2H4V A;  5KA7 A;  4YAA A;  5LXQ B;  2AHS A;  1OEM X;  4YR8 B;  3F99 A;  4NYH A;  1YWF A;  2I5X A;  2SHP A;  3QCE A;  1LYV A;  3QCG A;  4CVM A;  3ZM5 A;  2B49 A;  3OMH A;  2I4G A;  5AWX A;  3D1Q A;  3ZM2 A;  2HB1 A;  5J8R A;  2NLK A;  3V0I A;  3QKQ A;  1J6U A;  4ICZ A;  3V0H A;  2M3V A;  3QCL A;  4QUN A;  5KA8 A;  2F6Z A;  3RZ2 A;  4RI5 A;  3NRS A;  3V0F A;  5GTJ A;  2NT7 A;  3V0E A;  2Y1O A;  1JF7 A;  4KYQ A;  4Z6B A;  1ONZ A;  3I80 A;  1UAG A;  1T48 A;  1XM2 A;  4PVG A;  1AAX A;  1GWZ A;  2UUO A;  4JNB A;  1L8G A;  5KA2 A;  1G4W R; 
#chains in the Genus database with same CATH homology
 1JLN A;  1C85 A;  5KAC A;  3BLU A;  1LAR A;  4OHD A;  2CNE A;  1OEV A;  1PA1 A;  1PTU A;  1Q6M A;  4QAH A;  5IBS A;  2A3K A;  4RKK A;  1XXP A;  4GRY A;  1RPM A;  1P15 A;  4GFV A;  4OHE A;  5KA3 A;  2QBQ A;  1XRI A;  2J17 A;  1OEU A;  1YTS A;  5EHP A;  5M43 A;  1OHC A;  2CMA A;  4NND A;  1XXV A;  1WRM A;  1X24 A;  1PA9 A;  2B3O A;  2VEX A;  2I1Y A;  1OHE A;  1G7F A;  4ZRT A;  2MBC A;  2Y96 A;  3NME A;  4OHL A;  3ZMQ A;  3EAX A;  2BZL A;  5BZX A;  3AWF A;  1MKP A;  4R0S A;  2H04 A;  1ZC0 A;  4WOH A;  2PT0 A;  4QBW A;  4B04 A;  3U96 A;  4OHI A;  4BPC A;  3N0A A;  2I3U A;  3S4O A;  1G1G A;  2BGD A;  2VEU A;  3I7Z A;  2RF6 A;  5K22 A;  1XBO A;  3A5K A;  2QDC A;  2F6Y A;  1T4J A;  4D3P A;  3O4S A;  5K9V A;  2PI7 A;  4Y2E A;  2CM3 A;  4GWF A;  2OUD A;  1Q6T A;  1WCH A;  3EU0 A;  4GS0 A;  4QBE A;  2QCT A;  1Q6N A;  1YPT A;  1FQ1 A;  2HY3 A;  3LJ8 A;  4NX8 A;  3AWG A;  4J51 A;  5K25 A;  2F46 A;  2H4K A;  1ZZW A;  5K24 A;  5KAA A;  1NWL A;  4D3Q A;  2CM2 A;  2F71 A;  2GP0 A;  1Q6S A;  2G59 A;  2WGP A;  2HXP A;  2PA5 A;  4RH5 A;  5KAB A;  3OLR A;  5MMZ B;  2JJD A;  4D3R A;  1I9T A;  3ZM3 A;  2E0T A;  3M4U A;  5KA9 A;  5K23 A;  2B07 A;  1EEO A;  3S4E A;  3QCH A;  1NO6 A;  2CM8 A;  2Q05 A;  1U25 A;  2I6J A;  3QCD A;  2P4D A;  3F81 A;  3MMJ A;  4WU3 A;  2FJN A;  2YDU A;  2NV5 A;  3H2X A;  4ZN5 A;  5KA4 A;  2DXP A;  4HJP A;  1D5R A;  2GWO A;  3ZMP A;  2F6V A;  2VEV A;  4WTY A;  2CJZ A;  3CWE A;  3D44 A;  4BJO A;  2VEW A;  2HCM A;  1KAK A;  4HJQ A;  3S3E A;  2CMC A;  4GRZ A;  1OET A;  3D1O A;  2PSZ A;  2NT2 A;  1EEN A;  2QEP A;  4AZ1 A;  2J16 B;  2H4G A;  1U24 A;  3O4U A;  1C84 A;  2B4S A;  2I6P A;  3GXG A;  1T49 A;  3MOZ A;  4Y14 A;  4QUM A;  1YTN A;  1RXD A;  1PXH A;  3D42 A;  1Q6P A;  4ERC A;  4I8N A;  4RH9 A;  1NZ7 A;  3ZV2 A;  2I4E A;  1QXK A;  5KAD A;  2B4U A;  1C88 A;  2PBN A;  3V0G A;  1ECV A;  1GFY A;  5KA1 A;  2OOQ A;  1ZCL A;  1YN9 A;  3F41 A;  2I6M A;  4S0G A;  2C46 A;  3S3H A;  4GE6 A;  1OHD A;  4R30 A;  3QCK A;  2HC1 A;  2ESB A;  2GJT A;  3S3F A;  3ZM1 A;  4JMJ A;  3AWE A;  4JMK A;  1J4X A;  4GFU A;  1NWE A;  3QCM A;  2QBS A;  3D1H A;  4OHH A;  2QBR A;  1SUG A;  1G7G A;  5HDE A;  2J16 A;  2HVL A;  5BUG A;  3O4T A;  1BZC A;  1FPZ A;  1V3A A;  1I57 A;  1U26 A;  2CNH A;  4PYH A;  2I75 A;  5BX1 A;  2HC2 A;  2H02 A;  3A5J A;  1PH0 A;  3SME A;  2Y2F A;  3D9C A;  2OZ5 A;  1ONY A;  2G6Z A;  1PYN A;  2I6I A;  3EB1 A;  1Q1M A;  2B4P A;  5BZZ A;  3BRH A;  4H1O A;  1LQF A;  1YGU A;  3SR9 A;  4TVV A;  3RGQ A;  2F6T A;  2IMG A;  1FPR A;  3QCJ A;  3PS5 A;  2CMB A;  2QDM A;  2AZR A;  2HNQ A;  1C86 A;  3QKP A;  1OES A;  1YFO A;  2Q47 A;  1WAX A;  2FJM A;  4QAP A;  3QCI A;  1BZH A;  2CNF A;  3QCC A;  2VEY A;  4RHG A;  1ZCK A;  2NTA A;  2CM7 A;  3O3L A;  2CNG A;  2PQ5 A;  3S3K A;  1YZ4 A;  2QBP A;  4KYR A;  4R0T A;  2R0B A;  4JBC A;  2BGE A;  2I6O A;  3QCF A;  3F9A A;  4H34 A;  4KI9 A;  3CM3 A;  2BIJ A;  3GXH A;  1G1F A;  4WU2 A;  4MBB A;  4RI4 A;  1BZJ A;  2BV5 A;  3I36 A;  2F70 A;  4GE5 A;  2F6W A;  1NL9 A;  1Q6J A;  1QZ0 A;  2I42 A;  1KAV A;  2I3R A;  5EHR A;  1PTT A;  4DGP A;  2HNP A;  4ZI4 A;  1OEO X;  4IKC A;  5IBM A;  1NNY A;  3QCB A;  5I6V A;  2B4O A;  1G4U S;  1PTY A;  2CNI A;  3B7O A;  2QCJ A;  2QDP A;  3EMU A;  1PTV A;  4HRF A;  2NZ6 A;  2FH7 A;  2ZN7 A;  1L8K A;  3EZZ A;  1G1H A;  4GE2 A;  1C87 A;  2OC3 A;  2I4H A;  1I9S A;  1YTW A;  2A8B A;  3MOW A;  1A5Y A;  1YGR A;  4RDD A;  1R6H A;  2P6X A;  4NWG A;  2F6F A;  3BM8 A;  1VHR A;  5KA0 A;  4DGX A;  2H03 A;  3RO1 A;  3O5X A;  2ZMM A;  3V0D A;  4NWF A;  3RGO A;  3V0J A;  1C83 A;  3ZM0 A;  3BLT A;  5K9W A;  1M3G A;  3F9B A;  2C7S A;  3QCN A;  2CFV A;  2H4V A;  5KA7 A;  4YAA A;  5LXQ B;  2AHS A;  1OEM X;  4YR8 B;  3F99 A;  4NYH A;  1YWF A;  2I5X A;  2SHP A;  3QCE A;  1LYV A;  3QCG A;  2B49 A;  3OMH A;  2I4G A;  5AWX A;  3D1Q A;  3ZM2 A;  2HB1 A;  5J8R A;  2NLK A;  3V0I A;  3QKQ A;  4ICZ A;  3V0H A;  2M3V A;  3QCL A;  4QUN A;  5KA8 A;  2F6Z A;  3RZ2 A;  4RI5 A;  3V0F A;  5GTJ A;  2NT7 A;  3V0E A;  1JF7 A;  4KYQ A;  4Z6B A;  1ONZ A;  3I80 A;  1T48 A;  1XM2 A;  4PVG A;  1AAX A;  1GWZ A;  4JNB A;  1L8G A;  5KA2 A;  1G4W R; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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