4QN0A

Crystal structure of the cps-6 mutant q130k
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
239
structure length
238
Chain Sequence
SRSAEIMKHGYPGFTNVRTYEDFVLSYDYKTRTAHWVCEHLTPERLKHAGVDRKLCEFKPDITFPKKFLSQNTDYKCSGFDRGHLAAAGNHRKSQLAVDQTFYLSNMSPQVGRGFNRDKWNDLEMHCRRVAKKMINSYIITGPLYLPKLEGDGKKYIKYQVIGDNNVAVPTHFFKVALFEVTPGKFELESYILPNAVIEDTVEISKFHVPLDAVERSAGLEIFARLDPKSIVKENGAK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Oxidative Stress Impairs Cell Death by Repressing the Nuclease Activity of Mitochondrial Endonuclease G
pubmed doi rcsb
source organism Caenorhabditis elegans
molecule tags Hydrolase
molecule keywords Endonuclease G, mitochondrial
total genus 72
structure length 238
sequence length 239
chains with identical sequence B, C, D
ec nomenclature ec 3.1.30.-:
pdb deposition date 2014-06-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01223 Endonuclease_NS DNA/RNA non-specific endonuclease
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.570.10 Alpha Beta 3-Layer(aba) Sandwich Extracellular Endonuclease; Chain A Extracellular Endonuclease, subunit A 4qn0A00
3WAVA 1SMNA 5INHA 4GTYA 2XGRA 5L0EA 3NKOA 4ZG7A 3NKRA 4ZGAA 2XH3A 3NKNA 4ZG6A 5L0BA 4GTWA 3S5BA 5LQQA 1G8TA 3ISMA 5DLTA 5IJQA 3WAXA 5L0KA 5DLWA 4QGOA 5DLVA 5GKPA 4GTXA 5HRTA 3NKPA 4QN0A 3WAWA 3WAYA 4ZG9A 3OWVA 2XR9A 3NKQA 2XRGA 1ZM8A 5KXAA 5LIAA 1QL0A 5GKCA 4B56A 2O3BA 4GTZA 1QAEA 5IJSA 3NKMA 4E3YA 4QH0A 4A1NA
chains in the Genus database with same CATH superfamily
3WAVA 1SMNA 5INHA 4GTYA 2XGRA 5L0EA 3NKOA 4ZG7A 3NKRA 4ZGAA 2XH3A 3NKNA 4ZG6A 5L0BA 4GTWA 3S5BA 5LQQA 1G8TA 3ISMA 5DLTA 5IJQA 3WAXA 5L0KA 5DLWA 4QGOA 5DLVA 5GKPA 4GTXA 5HRTA 3NKPA 4QN0A 3WAWA 3WAYA 4ZG9A 3OWVA 2XR9A 3NKQA 2XRGA 1ZM8A 5KXAA 5LIAA 1QL0A 5GKCA 4B56A 2O3BA 4GTZA 1QAEA 5IJSA 3NKMA 4E3YA 4QH0A 4A1NA
chains in the Genus database with same CATH topology
3WAVA 1SMNA 5INHA 4GTYA 2XGRA 5L0EA 3NKOA 4ZG7A 3NKRA 4ZGAA 2XH3A 3NKNA 4ZG6A 5L0BA 4GTWA 3S5BA 5LQQA 1G8TA 3ISMA 5DLTA 5IJQA 3WAXA 5L0KA 5DLWA 4QGOA 5DLVA 5GKPA 4GTXA 5HRTA 3NKPA 4QN0A 3WAWA 3WAYA 4ZG9A 3OWVA 2XR9A 3NKQA 2XRGA 1ZM8A 5KXAA 5LIAA 1QL0A 5GKCA 4B56A 2O3BA 4GTZA 1QAEA 5IJSA 3NKMA 4E3YA 4QH0A 4A1NA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3WAV A;  1SMN A;  5INH A;  4GTY A;  2XGR A;  5L0E A;  3NKO A;  4ZG7 A;  3NKR A;  4ZGA A;  2XH3 A;  3NKN A;  4ZG6 A;  5L0B A;  4GTW A;  3S5B A;  5LQQ A;  1G8T A;  3ISM A;  5DLT A;  5IJQ A;  3WAX A;  5L0K A;  5DLW A;  4QGO A;  5DLV A;  5GKP A;  4GTX A;  5HRT A;  3NKP A;  4QN0 A;  3WAW A;  3WAY A;  4ZG9 A;  3OWV A;  2XR9 A;  3NKQ A;  2XRG A;  1ZM8 A;  5KXA A;  5LIA A;  1QL0 A;  5GKC A;  4B56 A;  2O3B A;  4GTZ A;  1QAE A;  5IJS A;  3NKM A;  4E3Y A;  4QH0 A;  4A1N A; 
#chains in the Genus database with same CATH topology
 3WAV A;  1SMN A;  5INH A;  4GTY A;  2XGR A;  5L0E A;  3NKO A;  4ZG7 A;  3NKR A;  4ZGA A;  2XH3 A;  3NKN A;  4ZG6 A;  5L0B A;  4GTW A;  3S5B A;  5LQQ A;  1G8T A;  3ISM A;  5DLT A;  5IJQ A;  3WAX A;  5L0K A;  5DLW A;  4QGO A;  5DLV A;  5GKP A;  4GTX A;  5HRT A;  3NKP A;  4QN0 A;  3WAW A;  3WAY A;  4ZG9 A;  3OWV A;  2XR9 A;  3NKQ A;  2XRG A;  1ZM8 A;  5KXA A;  5LIA A;  1QL0 A;  5GKC A;  4B56 A;  2O3B A;  4GTZ A;  1QAE A;  5IJS A;  3NKM A;  4E3Y A;  4QH0 A;  4A1N A; 
#chains in the Genus database with same CATH homology
 3WAV A;  1SMN A;  5INH A;  4GTY A;  2XGR A;  5L0E A;  3NKO A;  4ZG7 A;  3NKR A;  4ZGA A;  2XH3 A;  3NKN A;  4ZG6 A;  5L0B A;  4GTW A;  3S5B A;  5LQQ A;  1G8T A;  3ISM A;  5DLT A;  5IJQ A;  3WAX A;  5L0K A;  5DLW A;  4QGO A;  5DLV A;  5GKP A;  4GTX A;  5HRT A;  3NKP A;  4QN0 A;  3WAW A;  3WAY A;  4ZG9 A;  3OWV A;  2XR9 A;  3NKQ A;  2XRG A;  1ZM8 A;  5KXA A;  5LIA A;  1QL0 A;  5GKC A;  4B56 A;  2O3B A;  4GTZ A;  1QAE A;  5IJS A;  3NKM A;  4E3Y A;  4QH0 A;  4A1N A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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