4QR8A

Crystal structure of e coli pepq
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
sequence length
441
structure length
441
Chain Sequence
SLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis of substrate selectivity of E. coli prolidase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
molecule keywords Xaa-Pro dipeptidase
total genus 149
structure length 441
sequence length 441
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2014-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 4qr8A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4qr8A02
3RORA 2B3LA 1YW9A 2B3KA 2DFIA 2GU6A 1WY2A 3QOCA 3OVKA 3PKDA 2GZ5A 4A6VA 4FLJA 3BIPA 5E2CA 1YW7A 3MX6A 3PN9A 4B28A 2BWYA 4ZWUA 2HOWA 2BH3A 2BWSA 4S00A 1YJ3A 2BB7A 3MATA 4U6CA 5JI6A 2IW2A 3CTZA 4U6JA 2Q94A 1N51A 5CNXA 1WLRA 2OAZA 3OOOA 3FM3A 4ZNGA 4MATA 3TB5A 4IDYA 1A16A 2P99A 5JFRA 2GTXA 2BN7A 4R60A 1C27A 2P98A 4FO7A 1WL9A 2BHCA 2EVOA 4FLLA 1QXWA 1R5GA 1PV9A 1M35A 3BIQA 2GG8A 2EA4A 4U73A 4U6WA 1QXYA 5CIKA 5CDEA 2BWWA 1C24A 2EA2A 3L24A 1KQ9A 1XGNA 4U70A 3S6BA 5JHUA 2Q8KA 1W2MA 2EVCA 4Z7MA 1XGMA 2BWTA 4FUKA 3IU9A 3PEBA 2ZSGA 4RGZ1 4RZYA 2Q92A 4IF7A 4KM3A 4IKRA 2G6PA 1XGOA 4U1BA 4JUQA 3TAVA 1QZYA 2NQ7A 4IKTA 2ADUA 3FMQA 2GA2A 2GU5A 2GU4A 4PNCA 4U6ZA 2GG2A 2V3ZA 4FLIA 3PKBA 1XNZA 1BOAA 2GGCA 3IU7A 4ZWPA 1WKMA 4ZWOA 4U69A 3PKAA 1C21A 3IG4A 2V3YA 2V3XA 2BWXA 4U76A 4S2TP 5D6FA 2V6CA 1Y1NA 4FO8A 1R58A 3I7MA 5CDVA 4U71A 4IECA 1B59A 1KQ0A 2GG0A 5CE6A 5D6EA 1MATA 2OKNA 1R5HA 2NQ6A 5FCHA 2GG5A 4IU6A 1C23A 3RVAA 1WBQA 3D27A 2GU7A 2Q95A 3CB6A 3IU8A 4EGEA 2GGBA 4OOKA 5CLSA 2BHAA 5CDLA 1WN1A 3L7GA 3IL0A 1CHMA 1YW8A 2B3HA 2Q96A 2GG9A 3O5VA 2EVMA 4IKUA 4S2RP 4IKSA 3MR1A 3Q6DA 1BN5A 5E5BA 1O0XA 1QXZA 3PKEA 4U6EA 1W7VA 3BITA 4FKCA 1JAWA 2MATA 2P9AA 2BHDA 2BWUA 4FLKA 1KP0A 2BHBA 2GG7A 4QR8A 2GG3A 4U75A 4HXXA 5FCFA 3CB5A 1B6AA 4PV4A 4RZZA 1YVMA 2BWVA 2Q93A 4IPAA 3PKCA 3FMRA 4A6WA 1XGSA 4S01A 1WL6A 1C22A
chains in the Genus database with same CATH superfamily
3RORA 2B3LA 1YW9A 2B3KA 2DFIA 2GU6A 1WY2A 3QOCA 3OVKA 3PKDA 2GZ5A 4A6VA 4FLJA 3BIPA 5E2CA 1YW7A 3MX6A 3PN9A 4B28A 2BWYA 4ZWUA 2HOWA 2BH3A 2BWSA 4S00A 1YJ3A 2BB7A 3MATA 4U6CA 5JI6A 2IW2A 3CTZA 4U6JA 2Q94A 1N51A 5CNXA 1WLRA 2OAZA 3OOOA 3FM3A 4ZNGA 4MATA 3TB5A 4IDYA 1A16A 2P99A 5JFRA 2GTXA 2BN7A 4R60A 1C27A 2P98A 4FO7A 1WL9A 2BHCA 2EVOA 4FLLA 1QXWA 1R5GA 1PV9A 1M35A 3BIQA 2GG8A 2EA4A 4U73A 4U6WA 1QXYA 5CIKA 5CDEA 2BWWA 1C24A 2EA2A 3L24A 1KQ9A 1XGNA 4U70A 3S6BA 5JHUA 2Q8KA 1W2MA 2EVCA 4Z7MA 1XGMA 2BWTA 4FUKA 3IU9A 3PEBA 2ZSGA 4RGZ1 4RZYA 2Q92A 4IF7A 4KM3A 4IKRA 2G6PA 1XGOA 4U1BA 4JUQA 3TAVA 1QZYA 2NQ7A 4IKTA 2ADUA 3FMQA 2GA2A 2GU5A 2GU4A 4PNCA 4U6ZA 2GG2A 2V3ZA 4FLIA 3PKBA 1XNZA 1BOAA 2GGCA 3IU7A 4ZWPA 1WKMA 4ZWOA 4U69A 3PKAA 1C21A 3IG4A 2V3YA 2V3XA 2BWXA 4U76A 4S2TP 5D6FA 2V6CA 1Y1NA 4FO8A 1R58A 3I7MA 5CDVA 4U71A 4IECA 1B59A 1KQ0A 2GG0A 5CE6A 5D6EA 1MATA 2OKNA 1R5HA 2NQ6A 5FCHA 2GG5A 4IU6A 1C23A 3RVAA 1WBQA 3D27A 2GU7A 2Q95A 3CB6A 3IU8A 4EGEA 2GGBA 4OOKA 5CLSA 2BHAA 5CDLA 1WN1A 3L7GA 3IL0A 1CHMA 1YW8A 2B3HA 2Q96A 2GG9A 3O5VA 2EVMA 4IKUA 4S2RP 4IKSA 3MR1A 3Q6DA 1BN5A 5E5BA 1O0XA 1QXZA 3PKEA 4U6EA 1W7VA 3BITA 4FKCA 1JAWA 2MATA 2P9AA 2BHDA 2BWUA 4FLKA 1KP0A 2BHBA 2GG7A 4QR8A 2GG3A 4U75A 4HXXA 5FCFA 3CB5A 1B6AA 4PV4A 4RZZA 1YVMA 2BWVA 2Q93A 4IPAA 3PKCA 3FMRA 4A6WA 1XGSA 4S01A 1WL6A 1C22A
chains in the Genus database with same CATH topology
3RORA 2B3LA 1YW9A 2B3KA 2DFIA 2GU6A 1WY2A 3QOCA 3OVKA 3PKDA 2GZ5A 4A6VA 4FLJA 3BIPA 5E2CA 1YW7A 3MX6A 3PN9A 4B28A 2BWYA 4ZWUA 2HOWA 2BH3A 2BWSA 4S00A 1YJ3A 2BB7A 3MATA 4U6CA 5JI6A 2IW2A 3CTZA 4U6JA 2Q94A 1N51A 5CNXA 1WLRA 2OAZA 3OOOA 3FM3A 4ZNGA 4MATA 3TB5A 4IDYA 1A16A 2P99A 5JFRA 2GTXA 2BN7A 4R60A 1C27A 2P98A 4FO7A 1WL9A 2BHCA 2EVOA 4FLLA 1QXWA 1R5GA 1PV9A 1M35A 3BIQA 2GG8A 2EA4A 4U73A 4U6WA 1QXYA 5CIKA 5CDEA 2BWWA 1C24A 2EA2A 3L24A 1KQ9A 1XGNA 4U70A 3S6BA 5JHUA 2Q8KA 1W2MA 2EVCA 4Z7MA 1XGMA 2BWTA 4FUKA 3IU9A 3PEBA 2ZSGA 4RGZ1 4RZYA 2Q92A 4IF7A 4KM3A 4IKRA 2G6PA 1XGOA 4U1BA 4JUQA 3TAVA 1QZYA 2NQ7A 4IKTA 2ADUA 3FMQA 2GA2A 2GU5A 2GU4A 4PNCA 4U6ZA 2GG2A 2V3ZA 4FLIA 3PKBA 1XNZA 1BOAA 2GGCA 3IU7A 4ZWPA 1WKMA 4ZWOA 4U69A 3PKAA 1C21A 3IG4A 2V3YA 2V3XA 2BWXA 4U76A 4S2TP 5D6FA 2V6CA 1Y1NA 4FO8A 1R58A 3I7MA 5CDVA 4U71A 4IECA 1B59A 1KQ0A 2GG0A 5CE6A 5D6EA 1MATA 2OKNA 1R5HA 2NQ6A 5FCHA 2GG5A 4IU6A 1C23A 3RVAA 1WBQA 3D27A 2GU7A 2Q95A 3CB6A 3IU8A 4EGEA 2GGBA 4OOKA 5CLSA 2BHAA 5CDLA 1WN1A 3L7GA 3IL0A 1CHMA 1YW8A 2B3HA 2Q96A 2GG9A 3O5VA 2EVMA 4IKUA 4S2RP 4IKSA 3MR1A 3Q6DA 1BN5A 5E5BA 1O0XA 1QXZA 3PKEA 4U6EA 1W7VA 3BITA 4FKCA 1JAWA 2MATA 2P9AA 2BHDA 2BWUA 4FLKA 1KP0A 2BHBA 2GG7A 4QR8A 2GG3A 4U75A 4HXXA 5FCFA 3CB5A 1B6AA 4PV4A 4RZZA 1YVMA 2BWVA 2Q93A 4IPAA 3PKCA 3FMRA 4A6WA 1XGSA 4S01A 1WL6A 1C22A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3ROR A;  2B3L A;  1YW9 A;  2B3K A;  2DFI A;  2GU6 A;  1WY2 A;  3QOC A;  3OVK A;  3PKD A;  2GZ5 A;  4A6V A;  4FLJ A;  3BIP A;  5E2C A;  1YW7 A;  3MX6 A;  3PN9 A;  4B28 A;  2BWY A;  4ZWU A;  2HOW A;  2BH3 A;  2BWS A;  4S00 A;  1YJ3 A;  2BB7 A;  3MAT A;  4U6C A;  5JI6 A;  2IW2 A;  3CTZ A;  4U6J A;  2Q94 A;  1N51 A;  5CNX A;  1WLR A;  2OAZ A;  3OOO A;  3FM3 A;  4ZNG A;  4MAT A;  3TB5 A;  4IDY A;  1A16 A;  2P99 A;  5JFR A;  2GTX A;  2BN7 A;  4R60 A;  1C27 A;  2P98 A;  4FO7 A;  1WL9 A;  2BHC A;  2EVO A;  4FLL A;  1QXW A;  1R5G A;  1PV9 A;  1M35 A;  3BIQ A;  2GG8 A;  2EA4 A;  4U73 A;  4U6W A;  1QXY A;  5CIK A;  5CDE A;  2BWW A;  1C24 A;  2EA2 A;  3L24 A;  1KQ9 A;  1XGN A;  4U70 A;  3S6B A;  5JHU A;  2Q8K A;  1W2M A;  2EVC A;  4Z7M A;  1XGM A;  2BWT A;  4FUK A;  3IU9 A;  3PEB A;  2ZSG A;  4RGZ 1;  4RZY A;  2Q92 A;  4IF7 A;  4KM3 A;  4IKR A;  2G6P A;  1XGO A;  4U1B A;  4JUQ A;  3TAV A;  1QZY A;  2NQ7 A;  4IKT A;  2ADU A;  3FMQ A;  2GA2 A;  2GU5 A;  2GU4 A;  4PNC A;  4U6Z A;  2GG2 A;  2V3Z A;  4FLI A;  3PKB A;  1XNZ A;  1BOA A;  2GGC A;  3IU7 A;  4ZWP A;  1WKM A;  4ZWO A;  4U69 A;  3PKA A;  1C21 A;  3IG4 A;  2V3Y A;  2V3X A;  2BWX A;  4U76 A;  4S2T P;  5D6F A;  2V6C A;  1Y1N A;  4FO8 A;  1R58 A;  3I7M A;  5CDV A;  4U71 A;  4IEC A;  1B59 A;  1KQ0 A;  2GG0 A;  5CE6 A;  5D6E A;  1MAT A;  2OKN A;  1R5H A;  2NQ6 A;  5FCH A;  2GG5 A;  4IU6 A;  1C23 A;  3RVA A;  1WBQ A;  3D27 A;  2GU7 A;  2Q95 A;  3CB6 A;  3IU8 A;  4EGE A;  2GGB A;  4OOK A;  5CLS A;  2BHA A;  5CDL A;  1WN1 A;  3L7G A;  3IL0 A;  1CHM A;  1YW8 A;  2B3H A;  2Q96 A;  2GG9 A;  3O5V A;  2EVM A;  4IKU A;  4S2R P;  4IKS A;  3MR1 A;  3Q6D A;  1BN5 A;  5E5B A;  1O0X A;  1QXZ A;  3PKE A;  4U6E A;  1W7V A;  3BIT A;  4FKC A;  1JAW A;  2MAT A;  2P9A A;  2BHD A;  2BWU A;  4FLK A;  1KP0 A;  2BHB A;  2GG7 A;  4QR8 A;  2GG3 A;  4U75 A;  4HXX A;  5FCF A;  3CB5 A;  1B6A A;  4PV4 A;  4RZZ A;  1YVM A;  2BWV A;  2Q93 A;  4IPA A;  3PKC A;  3FMR A;  4A6W A;  1XGS A;  4S01 A;  1WL6 A;  1C22 A; 
#chains in the Genus database with same CATH topology
 3ROR A;  2B3L A;  1YW9 A;  2B3K A;  2DFI A;  2GU6 A;  1WY2 A;  3QOC A;  3OVK A;  3PKD A;  2GZ5 A;  4A6V A;  4FLJ A;  3BIP A;  5E2C A;  1YW7 A;  3MX6 A;  3PN9 A;  4B28 A;  2BWY A;  4ZWU A;  2HOW A;  2BH3 A;  2BWS A;  4S00 A;  1YJ3 A;  2BB7 A;  3MAT A;  4U6C A;  5JI6 A;  2IW2 A;  3CTZ A;  4U6J A;  2Q94 A;  1N51 A;  5CNX A;  1WLR A;  2OAZ A;  3OOO A;  3FM3 A;  4ZNG A;  4MAT A;  3TB5 A;  4IDY A;  1A16 A;  2P99 A;  5JFR A;  2GTX A;  2BN7 A;  4R60 A;  1C27 A;  2P98 A;  4FO7 A;  1WL9 A;  2BHC A;  2EVO A;  4FLL A;  1QXW A;  1R5G A;  1PV9 A;  1M35 A;  3BIQ A;  2GG8 A;  2EA4 A;  4U73 A;  4U6W A;  1QXY A;  5CIK A;  5CDE A;  2BWW A;  1C24 A;  2EA2 A;  3L24 A;  1KQ9 A;  1XGN A;  4U70 A;  3S6B A;  5JHU A;  2Q8K A;  1W2M A;  2EVC A;  4Z7M A;  1XGM A;  2BWT A;  4FUK A;  3IU9 A;  3PEB A;  2ZSG A;  4RGZ 1;  4RZY A;  2Q92 A;  4IF7 A;  4KM3 A;  4IKR A;  2G6P A;  1XGO A;  4U1B A;  4JUQ A;  3TAV A;  1QZY A;  2NQ7 A;  4IKT A;  2ADU A;  3FMQ A;  2GA2 A;  2GU5 A;  2GU4 A;  4PNC A;  4U6Z A;  2GG2 A;  2V3Z A;  4FLI A;  3PKB A;  1XNZ A;  1BOA A;  2GGC A;  3IU7 A;  4ZWP A;  1WKM A;  4ZWO A;  4U69 A;  3PKA A;  1C21 A;  3IG4 A;  2V3Y A;  2V3X A;  2BWX A;  4U76 A;  4S2T P;  5D6F A;  2V6C A;  1Y1N A;  4FO8 A;  1R58 A;  3I7M A;  5CDV A;  4U71 A;  4IEC A;  1B59 A;  1KQ0 A;  2GG0 A;  5CE6 A;  5D6E A;  1MAT A;  2OKN A;  1R5H A;  2NQ6 A;  5FCH A;  2GG5 A;  4IU6 A;  1C23 A;  3RVA A;  1WBQ A;  3D27 A;  2GU7 A;  2Q95 A;  3CB6 A;  3IU8 A;  4EGE A;  2GGB A;  4OOK A;  5CLS A;  2BHA A;  5CDL A;  1WN1 A;  3L7G A;  3IL0 A;  1CHM A;  1YW8 A;  2B3H A;  2Q96 A;  2GG9 A;  3O5V A;  2EVM A;  4IKU A;  4S2R P;  4IKS A;  3MR1 A;  3Q6D A;  1BN5 A;  5E5B A;  1O0X A;  1QXZ A;  3PKE A;  4U6E A;  1W7V A;  3BIT A;  4FKC A;  1JAW A;  2MAT A;  2P9A A;  2BHD A;  2BWU A;  4FLK A;  1KP0 A;  2BHB A;  2GG7 A;  4QR8 A;  2GG3 A;  4U75 A;  4HXX A;  5FCF A;  3CB5 A;  1B6A A;  4PV4 A;  4RZZ A;  1YVM A;  2BWV A;  2Q93 A;  4IPA A;  3PKC A;  3FMR A;  4A6W A;  1XGS A;  4S01 A;  1WL6 A;  1C22 A; 
#chains in the Genus database with same CATH homology
 3ROR A;  2B3L A;  1YW9 A;  2B3K A;  2DFI A;  2GU6 A;  1WY2 A;  3QOC A;  3OVK A;  3PKD A;  2GZ5 A;  4A6V A;  4FLJ A;  3BIP A;  5E2C A;  1YW7 A;  3MX6 A;  3PN9 A;  4B28 A;  2BWY A;  4ZWU A;  2HOW A;  2BH3 A;  2BWS A;  4S00 A;  1YJ3 A;  2BB7 A;  3MAT A;  4U6C A;  5JI6 A;  2IW2 A;  3CTZ A;  4U6J A;  2Q94 A;  1N51 A;  5CNX A;  1WLR A;  2OAZ A;  3OOO A;  3FM3 A;  4ZNG A;  4MAT A;  3TB5 A;  4IDY A;  1A16 A;  2P99 A;  5JFR A;  2GTX A;  2BN7 A;  4R60 A;  1C27 A;  2P98 A;  4FO7 A;  1WL9 A;  2BHC A;  2EVO A;  4FLL A;  1QXW A;  1R5G A;  1PV9 A;  1M35 A;  3BIQ A;  2GG8 A;  2EA4 A;  4U73 A;  4U6W A;  1QXY A;  5CIK A;  5CDE A;  2BWW A;  1C24 A;  2EA2 A;  3L24 A;  1KQ9 A;  1XGN A;  4U70 A;  3S6B A;  5JHU A;  2Q8K A;  1W2M A;  2EVC A;  4Z7M A;  1XGM A;  2BWT A;  4FUK A;  3IU9 A;  3PEB A;  2ZSG A;  4RGZ 1;  4RZY A;  2Q92 A;  4IF7 A;  4KM3 A;  4IKR A;  2G6P A;  1XGO A;  4U1B A;  4JUQ A;  3TAV A;  1QZY A;  2NQ7 A;  4IKT A;  2ADU A;  3FMQ A;  2GA2 A;  2GU5 A;  2GU4 A;  4PNC A;  4U6Z A;  2GG2 A;  2V3Z A;  4FLI A;  3PKB A;  1XNZ A;  1BOA A;  2GGC A;  3IU7 A;  4ZWP A;  1WKM A;  4ZWO A;  4U69 A;  3PKA A;  1C21 A;  3IG4 A;  2V3Y A;  2V3X A;  2BWX A;  4U76 A;  4S2T P;  5D6F A;  2V6C A;  1Y1N A;  4FO8 A;  1R58 A;  3I7M A;  5CDV A;  4U71 A;  4IEC A;  1B59 A;  1KQ0 A;  2GG0 A;  5CE6 A;  5D6E A;  1MAT A;  2OKN A;  1R5H A;  2NQ6 A;  5FCH A;  2GG5 A;  4IU6 A;  1C23 A;  3RVA A;  1WBQ A;  3D27 A;  2GU7 A;  2Q95 A;  3CB6 A;  3IU8 A;  4EGE A;  2GGB A;  4OOK A;  5CLS A;  2BHA A;  5CDL A;  1WN1 A;  3L7G A;  3IL0 A;  1CHM A;  1YW8 A;  2B3H A;  2Q96 A;  2GG9 A;  3O5V A;  2EVM A;  4IKU A;  4S2R P;  4IKS A;  3MR1 A;  3Q6D A;  1BN5 A;  5E5B A;  1O0X A;  1QXZ A;  3PKE A;  4U6E A;  1W7V A;  3BIT A;  4FKC A;  1JAW A;  2MAT A;  2P9A A;  2BHD A;  2BWU A;  4FLK A;  1KP0 A;  2BHB A;  2GG7 A;  4QR8 A;  2GG3 A;  4U75 A;  4HXX A;  5FCF A;  3CB5 A;  1B6A A;  4PV4 A;  4RZZ A;  1YVM A;  2BWV A;  2Q93 A;  4IPA A;  3PKC A;  3FMR A;  4A6W A;  1XGS A;  4S01 A;  1WL6 A;  1C22 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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