4QR8A

Crystal structure of e coli pepq
Total Genus 149
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
149
sequence length
441
structure length
441
Chain Sequence
SLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Xaa-Pro dipeptidase
publication title Structural basis of substrate selectivity of E. coli prolidase.
pubmed doi rcsb
source organism Escherichia coli
molecule tags Hydrolase
total genus 149
structure length 441
sequence length 441
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2014-06-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 4qr8A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4qr8A02
3Q6DA 5CE6A 2NQ6A 2ZSGA 3L7GA 1QXYA 4U6CA 4U71A 4MATA 5FCFA 5JFRA 1MATA 2Q92A 3D27A 2BH3A 1XNZA 4B28A 4OOKA 5CDLA 2IW2A 4S01A 1C27A 2P99A 2V6CA 1XGNA 2OAZA 4S2RP 3PKCA 2GU7A 2BWYA 2HOWA 4S2TP 4KM3A 4A6WA 2EVCA 2MATA 1KP0A 3TB5A 4IECA 3PKEA 4S00A 3QOCA 4U6ZA 4QR8A 4U6EA 3BITA 4FUKA 2ADUA 1A16A 4PV4A 2GU5A 2EA2A 2GU6A 4FLLA 2Q94A 1N51A 1C22A 1QZYA 4FO7A 2BWUA 1QXZA 1YW9A 1WKMA 2EA4A 3S6BA 3I7MA 3BIQA 2GU4A 3FMQA 1CHMA 4ZWUA 3IU7A 1YW7A 3O5VA 4IDYA 4A6VA 1YW8A 1WBQA 1C23A 4HXXA 1WL9A 1XGMA 4IKRA 4JUQA 4ZNGA 2OKNA 1XGSA 1R5HA 2Q93A 4U76A 3OVKA 4IF7A 2BN7A 2GGCA 3IU8A 4RZYA 1O0XA 2BHDA 2BWVA 2V3ZA 1KQ0A 2BWWA 4IKTA 3IG4A 3RORA 1C24A 3MX6A 1R58A 4FO8A 1WL6A 1BN5A 5FCHA 2V3YA 4R60A 1R5GA 2GG2A 4U6WA 1JAWA 1W2MA 3PN9A 2BB7A 2EVMA 3PKBA 1WY2A 2Q8KA 4U70A 4PNCA 5CNXA 3BIPA 3CB6A 2GTXA 1YVMA 1Y1NA 1B59A 5CDEA 4RZZA 3MR1A 4U6JA 4IU6A 3IL0A 2Q96A 3FM3A 2GG8A 4IPAA 5JI6A 5E5BA 2G6PA 3PEBA 4IKUA 4Z7MA 2V3XA 1BOAA 3FMRA 3MATA 2BHCA 2B3HA 2GG3A 4IKSA 1XGOA 4FKCA 2P98A 4EGEA 2GA2A 2GG0A 3IU9A 5D6FA 2Q95A 3CB5A 1WLRA 2GG5A 4FLJA 4FLKA 2GG7A 3TAVA 2DFIA 3PKDA 1YJ3A 3PKAA 2BWSA 5CIKA 4ZWPA 5CLSA 5JHUA 2NQ7A 2BWXA 1QXWA 1PV9A 1KQ9A 3RVAA 1B6AA 2B3LA 2GZ5A 2GG9A 3L24A 5CDVA 1W7VA 4RGZ1 5E2CA 2BHAA 4FLIA 4U75A 1WN1A 2BHBA 4U1BA 4U69A 2BWTA 3CTZA 2GGBA 2P9AA 5D6EA 2EVOA 2B3KA 4ZWOA 4U73A 3OOOA 1C21A 1M35A
chains in the Genus database with same CATH superfamily
3Q6DA 5CE6A 2NQ6A 2ZSGA 3L7GA 1QXYA 4U6CA 4U71A 4MATA 5FCFA 5JFRA 1MATA 2Q92A 3D27A 2BH3A 1XNZA 4B28A 4OOKA 5CDLA 2IW2A 4S01A 1C27A 2P99A 2V6CA 1XGNA 2OAZA 4S2RP 3PKCA 2GU7A 2BWYA 2HOWA 4S2TP 4KM3A 4A6WA 2EVCA 2MATA 1KP0A 3TB5A 4IECA 3PKEA 4S00A 3QOCA 4U6ZA 4QR8A 4U6EA 3BITA 4FUKA 2ADUA 1A16A 4PV4A 2GU5A 2EA2A 2GU6A 4FLLA 2Q94A 1N51A 1C22A 1QZYA 4FO7A 2BWUA 1QXZA 1YW9A 1WKMA 2EA4A 3S6BA 3I7MA 3BIQA 2GU4A 3FMQA 1CHMA 4ZWUA 3IU7A 1YW7A 3O5VA 4IDYA 4A6VA 1YW8A 1WBQA 1C23A 4HXXA 1WL9A 1XGMA 4IKRA 4JUQA 4ZNGA 2OKNA 1XGSA 1R5HA 2Q93A 4U76A 3OVKA 4IF7A 2BN7A 2GGCA 3IU8A 4RZYA 1O0XA 2BHDA 2BWVA 2V3ZA 1KQ0A 2BWWA 4IKTA 3IG4A 3RORA 1C24A 3MX6A 1R58A 4FO8A 1WL6A 1BN5A 5FCHA 2V3YA 4R60A 1R5GA 2GG2A 4U6WA 1JAWA 1W2MA 3PN9A 2BB7A 2EVMA 3PKBA 1WY2A 2Q8KA 4U70A 4PNCA 5CNXA 3BIPA 3CB6A 2GTXA 1YVMA 1Y1NA 1B59A 5CDEA 4RZZA 3MR1A 4U6JA 4IU6A 3IL0A 2Q96A 3FM3A 2GG8A 4IPAA 5JI6A 5E5BA 2G6PA 3PEBA 4IKUA 4Z7MA 2V3XA 1BOAA 3FMRA 3MATA 2BHCA 2B3HA 2GG3A 4IKSA 1XGOA 4FKCA 2P98A 4EGEA 2GA2A 2GG0A 3IU9A 5D6FA 2Q95A 3CB5A 1WLRA 2GG5A 4FLJA 4FLKA 2GG7A 3TAVA 2DFIA 3PKDA 1YJ3A 3PKAA 2BWSA 5CIKA 4ZWPA 5CLSA 5JHUA 2NQ7A 2BWXA 1QXWA 1PV9A 1KQ9A 3RVAA 1B6AA 2B3LA 2GZ5A 2GG9A 3L24A 5CDVA 1W7VA 4RGZ1 5E2CA 2BHAA 4FLIA 4U75A 1WN1A 2BHBA 4U1BA 4U69A 2BWTA 3CTZA 2GGBA 2P9AA 5D6EA 2EVOA 2B3KA 4ZWOA 4U73A 3OOOA 1C21A 1M35A
chains in the Genus database with same CATH topology
3Q6DA 5CE6A 2NQ6A 2ZSGA 3L7GA 1QXYA 4U6CA 4U71A 4MATA 5FCFA 5JFRA 1MATA 2Q92A 3D27A 2BH3A 1XNZA 4B28A 4OOKA 5CDLA 2IW2A 4S01A 1C27A 2P99A 2V6CA 1XGNA 2OAZA 4S2RP 3PKCA 2GU7A 2BWYA 2HOWA 4S2TP 4KM3A 4A6WA 2EVCA 2MATA 1KP0A 3TB5A 4IECA 3PKEA 4S00A 3QOCA 4U6ZA 4QR8A 4U6EA 3BITA 4FUKA 2ADUA 1A16A 4PV4A 2GU5A 2EA2A 2GU6A 4FLLA 2Q94A 1N51A 1C22A 1QZYA 4FO7A 2BWUA 1QXZA 1YW9A 1WKMA 2EA4A 3S6BA 3I7MA 3BIQA 2GU4A 3FMQA 1CHMA 4ZWUA 3IU7A 1YW7A 3O5VA 4IDYA 4A6VA 1YW8A 1WBQA 1C23A 4HXXA 1WL9A 1XGMA 4IKRA 4JUQA 4ZNGA 2OKNA 1XGSA 1R5HA 2Q93A 4U76A 3OVKA 4IF7A 2BN7A 2GGCA 3IU8A 4RZYA 1O0XA 2BHDA 2BWVA 2V3ZA 1KQ0A 2BWWA 4IKTA 3IG4A 3RORA 1C24A 3MX6A 1R58A 4FO8A 1WL6A 1BN5A 5FCHA 2V3YA 4R60A 1R5GA 2GG2A 4U6WA 1JAWA 1W2MA 3PN9A 2BB7A 2EVMA 3PKBA 1WY2A 2Q8KA 4U70A 4PNCA 5CNXA 3BIPA 3CB6A 2GTXA 1YVMA 1Y1NA 1B59A 5CDEA 4RZZA 3MR1A 4U6JA 4IU6A 3IL0A 2Q96A 3FM3A 2GG8A 4IPAA 5JI6A 5E5BA 2G6PA 3PEBA 4IKUA 4Z7MA 2V3XA 1BOAA 3FMRA 3MATA 2BHCA 2B3HA 2GG3A 4IKSA 1XGOA 4FKCA 2P98A 4EGEA 2GA2A 2GG0A 3IU9A 5D6FA 2Q95A 3CB5A 1WLRA 2GG5A 4FLJA 4FLKA 2GG7A 3TAVA 2DFIA 3PKDA 1YJ3A 3PKAA 2BWSA 5CIKA 4ZWPA 5CLSA 5JHUA 2NQ7A 2BWXA 1QXWA 1PV9A 1KQ9A 3RVAA 1B6AA 2B3LA 2GZ5A 2GG9A 3L24A 5CDVA 1W7VA 4RGZ1 5E2CA 2BHAA 4FLIA 4U75A 1WN1A 2BHBA 4U1BA 4U69A 2BWTA 3CTZA 2GGBA 2P9AA 5D6EA 2EVOA 2B3KA 4ZWOA 4U73A 3OOOA 1C21A 1M35A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3Q6D A;  5CE6 A;  2NQ6 A;  2ZSG A;  3L7G A;  1QXY A;  4U6C A;  4U71 A;  4MAT A;  5FCF A;  5JFR A;  1MAT A;  2Q92 A;  3D27 A;  2BH3 A;  1XNZ A;  4B28 A;  4OOK A;  5CDL A;  2IW2 A;  4S01 A;  1C27 A;  2P99 A;  2V6C A;  1XGN A;  2OAZ A;  4S2R P;  3PKC A;  2GU7 A;  2BWY A;  2HOW A;  4S2T P;  4KM3 A;  4A6W A;  2EVC A;  2MAT A;  1KP0 A;  3TB5 A;  4IEC A;  3PKE A;  4S00 A;  3QOC A;  4U6Z A;  4QR8 A;  4U6E A;  3BIT A;  4FUK A;  2ADU A;  1A16 A;  4PV4 A;  2GU5 A;  2EA2 A;  2GU6 A;  4FLL A;  2Q94 A;  1N51 A;  1C22 A;  1QZY A;  4FO7 A;  2BWU A;  1QXZ A;  1YW9 A;  1WKM A;  2EA4 A;  3S6B A;  3I7M A;  3BIQ A;  2GU4 A;  3FMQ A;  1CHM A;  4ZWU A;  3IU7 A;  1YW7 A;  3O5V A;  4IDY A;  4A6V A;  1YW8 A;  1WBQ A;  1C23 A;  4HXX A;  1WL9 A;  1XGM A;  4IKR A;  4JUQ A;  4ZNG A;  2OKN A;  1XGS A;  1R5H A;  2Q93 A;  4U76 A;  3OVK A;  4IF7 A;  2BN7 A;  2GGC A;  3IU8 A;  4RZY A;  1O0X A;  2BHD A;  2BWV A;  2V3Z A;  1KQ0 A;  2BWW A;  4IKT A;  3IG4 A;  3ROR A;  1C24 A;  3MX6 A;  1R58 A;  4FO8 A;  1WL6 A;  1BN5 A;  5FCH A;  2V3Y A;  4R60 A;  1R5G A;  2GG2 A;  4U6W A;  1JAW A;  1W2M A;  3PN9 A;  2BB7 A;  2EVM A;  3PKB A;  1WY2 A;  2Q8K A;  4U70 A;  4PNC A;  5CNX A;  3BIP A;  3CB6 A;  2GTX A;  1YVM A;  1Y1N A;  1B59 A;  5CDE A;  4RZZ A;  3MR1 A;  4U6J A;  4IU6 A;  3IL0 A;  2Q96 A;  3FM3 A;  2GG8 A;  4IPA A;  5JI6 A;  5E5B A;  2G6P A;  3PEB A;  4IKU A;  4Z7M A;  2V3X A;  1BOA A;  3FMR A;  3MAT A;  2BHC A;  2B3H A;  2GG3 A;  4IKS A;  1XGO A;  4FKC A;  2P98 A;  4EGE A;  2GA2 A;  2GG0 A;  3IU9 A;  5D6F A;  2Q95 A;  3CB5 A;  1WLR A;  2GG5 A;  4FLJ A;  4FLK A;  2GG7 A;  3TAV A;  2DFI A;  3PKD A;  1YJ3 A;  3PKA A;  2BWS A;  5CIK A;  4ZWP A;  5CLS A;  5JHU A;  2NQ7 A;  2BWX A;  1QXW A;  1PV9 A;  1KQ9 A;  3RVA A;  1B6A A;  2B3L A;  2GZ5 A;  2GG9 A;  3L24 A;  5CDV A;  1W7V A;  4RGZ 1;  5E2C A;  2BHA A;  4FLI A;  4U75 A;  1WN1 A;  2BHB A;  4U1B A;  4U69 A;  2BWT A;  3CTZ A;  2GGB A;  2P9A A;  5D6E A;  2EVO A;  2B3K A;  4ZWO A;  4U73 A;  3OOO A;  1C21 A;  1M35 A; 
#chains in the Genus database with same CATH topology
 3Q6D A;  5CE6 A;  2NQ6 A;  2ZSG A;  3L7G A;  1QXY A;  4U6C A;  4U71 A;  4MAT A;  5FCF A;  5JFR A;  1MAT A;  2Q92 A;  3D27 A;  2BH3 A;  1XNZ A;  4B28 A;  4OOK A;  5CDL A;  2IW2 A;  4S01 A;  1C27 A;  2P99 A;  2V6C A;  1XGN A;  2OAZ A;  4S2R P;  3PKC A;  2GU7 A;  2BWY A;  2HOW A;  4S2T P;  4KM3 A;  4A6W A;  2EVC A;  2MAT A;  1KP0 A;  3TB5 A;  4IEC A;  3PKE A;  4S00 A;  3QOC A;  4U6Z A;  4QR8 A;  4U6E A;  3BIT A;  4FUK A;  2ADU A;  1A16 A;  4PV4 A;  2GU5 A;  2EA2 A;  2GU6 A;  4FLL A;  2Q94 A;  1N51 A;  1C22 A;  1QZY A;  4FO7 A;  2BWU A;  1QXZ A;  1YW9 A;  1WKM A;  2EA4 A;  3S6B A;  3I7M A;  3BIQ A;  2GU4 A;  3FMQ A;  1CHM A;  4ZWU A;  3IU7 A;  1YW7 A;  3O5V A;  4IDY A;  4A6V A;  1YW8 A;  1WBQ A;  1C23 A;  4HXX A;  1WL9 A;  1XGM A;  4IKR A;  4JUQ A;  4ZNG A;  2OKN A;  1XGS A;  1R5H A;  2Q93 A;  4U76 A;  3OVK A;  4IF7 A;  2BN7 A;  2GGC A;  3IU8 A;  4RZY A;  1O0X A;  2BHD A;  2BWV A;  2V3Z A;  1KQ0 A;  2BWW A;  4IKT A;  3IG4 A;  3ROR A;  1C24 A;  3MX6 A;  1R58 A;  4FO8 A;  1WL6 A;  1BN5 A;  5FCH A;  2V3Y A;  4R60 A;  1R5G A;  2GG2 A;  4U6W A;  1JAW A;  1W2M A;  3PN9 A;  2BB7 A;  2EVM A;  3PKB A;  1WY2 A;  2Q8K A;  4U70 A;  4PNC A;  5CNX A;  3BIP A;  3CB6 A;  2GTX A;  1YVM A;  1Y1N A;  1B59 A;  5CDE A;  4RZZ A;  3MR1 A;  4U6J A;  4IU6 A;  3IL0 A;  2Q96 A;  3FM3 A;  2GG8 A;  4IPA A;  5JI6 A;  5E5B A;  2G6P A;  3PEB A;  4IKU A;  4Z7M A;  2V3X A;  1BOA A;  3FMR A;  3MAT A;  2BHC A;  2B3H A;  2GG3 A;  4IKS A;  1XGO A;  4FKC A;  2P98 A;  4EGE A;  2GA2 A;  2GG0 A;  3IU9 A;  5D6F A;  2Q95 A;  3CB5 A;  1WLR A;  2GG5 A;  4FLJ A;  4FLK A;  2GG7 A;  3TAV A;  2DFI A;  3PKD A;  1YJ3 A;  3PKA A;  2BWS A;  5CIK A;  4ZWP A;  5CLS A;  5JHU A;  2NQ7 A;  2BWX A;  1QXW A;  1PV9 A;  1KQ9 A;  3RVA A;  1B6A A;  2B3L A;  2GZ5 A;  2GG9 A;  3L24 A;  5CDV A;  1W7V A;  4RGZ 1;  5E2C A;  2BHA A;  4FLI A;  4U75 A;  1WN1 A;  2BHB A;  4U1B A;  4U69 A;  2BWT A;  3CTZ A;  2GGB A;  2P9A A;  5D6E A;  2EVO A;  2B3K A;  4ZWO A;  4U73 A;  3OOO A;  1C21 A;  1M35 A; 
#chains in the Genus database with same CATH homology
 3Q6D A;  5CE6 A;  2NQ6 A;  2ZSG A;  3L7G A;  1QXY A;  4U6C A;  4U71 A;  4MAT A;  5FCF A;  5JFR A;  1MAT A;  2Q92 A;  3D27 A;  2BH3 A;  1XNZ A;  4B28 A;  4OOK A;  5CDL A;  2IW2 A;  4S01 A;  1C27 A;  2P99 A;  2V6C A;  1XGN A;  2OAZ A;  4S2R P;  3PKC A;  2GU7 A;  2BWY A;  2HOW A;  4S2T P;  4KM3 A;  4A6W A;  2EVC A;  2MAT A;  1KP0 A;  3TB5 A;  4IEC A;  3PKE A;  4S00 A;  3QOC A;  4U6Z A;  4QR8 A;  4U6E A;  3BIT A;  4FUK A;  2ADU A;  1A16 A;  4PV4 A;  2GU5 A;  2EA2 A;  2GU6 A;  4FLL A;  2Q94 A;  1N51 A;  1C22 A;  1QZY A;  4FO7 A;  2BWU A;  1QXZ A;  1YW9 A;  1WKM A;  2EA4 A;  3S6B A;  3I7M A;  3BIQ A;  2GU4 A;  3FMQ A;  1CHM A;  4ZWU A;  3IU7 A;  1YW7 A;  3O5V A;  4IDY A;  4A6V A;  1YW8 A;  1WBQ A;  1C23 A;  4HXX A;  1WL9 A;  1XGM A;  4IKR A;  4JUQ A;  4ZNG A;  2OKN A;  1XGS A;  1R5H A;  2Q93 A;  4U76 A;  3OVK A;  4IF7 A;  2BN7 A;  2GGC A;  3IU8 A;  4RZY A;  1O0X A;  2BHD A;  2BWV A;  2V3Z A;  1KQ0 A;  2BWW A;  4IKT A;  3IG4 A;  3ROR A;  1C24 A;  3MX6 A;  1R58 A;  4FO8 A;  1WL6 A;  1BN5 A;  5FCH A;  2V3Y A;  4R60 A;  1R5G A;  2GG2 A;  4U6W A;  1JAW A;  1W2M A;  3PN9 A;  2BB7 A;  2EVM A;  3PKB A;  1WY2 A;  2Q8K A;  4U70 A;  4PNC A;  5CNX A;  3BIP A;  3CB6 A;  2GTX A;  1YVM A;  1Y1N A;  1B59 A;  5CDE A;  4RZZ A;  3MR1 A;  4U6J A;  4IU6 A;  3IL0 A;  2Q96 A;  3FM3 A;  2GG8 A;  4IPA A;  5JI6 A;  5E5B A;  2G6P A;  3PEB A;  4IKU A;  4Z7M A;  2V3X A;  1BOA A;  3FMR A;  3MAT A;  2BHC A;  2B3H A;  2GG3 A;  4IKS A;  1XGO A;  4FKC A;  2P98 A;  4EGE A;  2GA2 A;  2GG0 A;  3IU9 A;  5D6F A;  2Q95 A;  3CB5 A;  1WLR A;  2GG5 A;  4FLJ A;  4FLK A;  2GG7 A;  3TAV A;  2DFI A;  3PKD A;  1YJ3 A;  3PKA A;  2BWS A;  5CIK A;  4ZWP A;  5CLS A;  5JHU A;  2NQ7 A;  2BWX A;  1QXW A;  1PV9 A;  1KQ9 A;  3RVA A;  1B6A A;  2B3L A;  2GZ5 A;  2GG9 A;  3L24 A;  5CDV A;  1W7V A;  4RGZ 1;  5E2C A;  2BHA A;  4FLI A;  4U75 A;  1WN1 A;  2BHB A;  4U1B A;  4U69 A;  2BWT A;  3CTZ A;  2GGB A;  2P9A A;  5D6E A;  2EVO A;  2B3K A;  4ZWO A;  4U73 A;  3OOO A;  1C21 A;  1M35 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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