4R0AA

Crystal structure of human tlr8 in complex with uridine mononucleoside
Total Genus 251
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
251
sequence length
786
structure length
748
Chain Sequence
RSYPCDEKKQNDSVIAECSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISRLINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSSNLLKTINKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRLVDVICASPGDQRGKSIVSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule keywords Toll-like receptor 8
publication title Toll-like receptor 8 senses degradation products of single-stranded RNA.
pubmed doi rcsb
source organism Homo sapiens
molecule tags Immune system
total genus 251
structure length 748
sequence length 786
ec nomenclature
pdb deposition date 2014-07-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00560 LRR_1 Leucine Rich Repeat
A PF13855 LRR_8 Leucine rich repeat
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.80.10.10 Alpha Beta Alpha-Beta Horseshoe Leucine-rich repeat, LRR (right-handed beta-alpha superhelix) Ribonuclease Inhibitor 4r0aA00
4CNCA 1O6VA 5LFNA 1H6TA 2OMTA 5B0NA 5IJDA 2V9SA 1DS9A 4QBZA 4V2EA 3O53A 1OZNA 2P1OB 3UL8A 4U09A 3WPIA 2WQWA 5D3IA 5HZLB 4R5CA 4AW4A 2UZXA 3ULVA 4IM6A 4LSXC 4Q3GA 2P1NB 3WPGA 1OTNA 3G04C 1DCEA 5GS2B 4ECNA 5AWBA 1K5DC 5CMPA 2Z62A 4L3AA 1U0ND 5A5CA 4FDWA 4R5DA 4CC4C 2Z63A 4CILA 3OGKB 1PGVA 4LXRA 4I6JB 2Q4GW 4KT1A 4PERA 4V2DA 3DZEA 2OMZA 2P1PB 1XWDC 2Y5QA 5B4PA 5AWAA 2OMWA 4RWTC 5GQRK 4C2BB 4L3FA 3RGXA 4U08A 4NKGA 4PKIG 3OJAB 4ARNA 4R08A 4J0MA 2P1MB 1SQ0B 3WPCA 4Y61B 2JQDA 3CIGA 3VQ1A 1LTXA 2OMVA 2WQVA 3A79B 3UL9A 2A0ZA 5IJCA 2P1QB 4PQ8A 4WP6A 4QC0A 3M19A 4M7EC 5GMHA 2WQUA 2ASSB 4ARRA 4FHOA 3UL7A 4Z61C 3TSRE 4LSXA 4TZHA 4K17A 4BV4R 1OTMA 2R9UA 2ELLA 3E6JA 2WFHA 3ZYNA 4LI2A 4XGOA 4QXEA 3WN4A 4Q62A 3OJAA 3KJ4A 4RCAB 5IJBA 5AZ5A 4G8AA 4LXSA 4R09A 3E4GA 2V9TB 2XWTC 1M9LA 1M10B 1WWLA 1FO1A 4Z94G 4Z8GA 1G9UA 3G39A 3ZYIA 5GMGA 4ECOA 2XOTA 4CNMA 1GWBA 3RFJA 2O6SA 4LSCA 3VQ2A 3JB9j 4R0AA 4MN8B 4CP6A 3W3KA 1O6SA 3WPDA 3RFSA 1XKUA 1D0BA 4PSJA 3RW7A 3PMHG 3OGMB 1A4YA 4KXFB 2BEXA 4H09A 1M9SA 2Z66A 4NKHA 3W3MA 4LSAA 3W3LA 4FD0A 4R07A 4HQ1A 1XECA 2CA6A 4FCGA 1JL5A 3REZA 5CMNA 3RFEA 4R6FA 5AWCA 3ULAA 4Z79A 3RIZA 1FT8A 2Z7XB 4R58A 3M18A 3G3AA 1XEUA 4WYKA 1K5GC 2WQXA 4XOSA 4AY9X 4Z64C 1W8AA 3W3JA 1Z7XW 3G06A 1A9NA 4P91A 4EZGA 2Z65A 5IYXC 3G3BA 5GS0A 4FS7A 3P72A 2Z64A 4Q3IA 5FTTB 4R6JA 3E3ZA 1OOKG 3C6NB 4BSSA 1OGQA 5AWDA 3RW6A 4V2CA 2RR6A 3ULUA 2ASTB 4C2AB 2ID5A 2Z7XA 3WPFA 4CC4A 4RCWA 4GLPA 1P8VA 1YRGA 1ZIWA 1DFJI 2V70A 1FS2A 3FXIA 4GT6A 3OGLB 3WPHA 1H6UA 1KOHA 3CIYA 2OMXA 4FMZA 1M0ZA 3GOZA 3W3GA 5GMFA 3WPBA 3CVRA 1FQVA 2IFGA 4OQTA 4BSRA 4PEQB 2Z82A 1XCDA 3SB4A 3C6PB 4U7LA 3E2JA 2RA8A 1KOOA 2O6RA 1IO0A 2Z81A 4XSQA 3C6OB 2BNHA 2FT3A 5HDHA 4MQWX 1OTOA 4J4LA 1P8TA 4R6AA 4R6GA 1O6TA 1P9AG 2O6QA 4M7EA 2JE0A 3RGZA 3O6NA 3RJ0A 4B8CD 3WPEA 3ZYOA 4U06A 3UN9A 1QYYA 4LI1A 2OMUA 3W3NA 4KNGA 4YEBB 4P8SA 4BSUA 5B0TA 2UZYA 3BZ5A 4UFRA 2OMYA 3ZYJA 2JE1A
chains in the Genus database with same CATH superfamily
4CNCA 1O6VA 5LFNA 1H6TA 2OMTA 5B0NA 5IJDA 2V9SA 1DS9A 4QBZA 4V2EA 3O53A 1OZNA 2P1OB 3UL8A 4U09A 3WPIA 2WQWA 5D3IA 5HZLB 4R5CA 4AW4A 2UZXA 3ULVA 4IM6A 4LSXC 4Q3GA 2P1NB 3WPGA 1OTNA 3G04C 1DCEA 5GS2B 4ECNA 5AWBA 1K5DC 5CMPA 2Z62A 4L3AA 1U0ND 5A5CA 4FDWA 4R5DA 4CC4C 2Z63A 4CILA 3OGKB 1PGVA 4LXRA 4I6JB 2Q4GW 4KT1A 4PERA 4V2DA 3DZEA 2OMZA 2P1PB 1XWDC 2Y5QA 5B4PA 5AWAA 2OMWA 4RWTC 5GQRK 4C2BB 4L3FA 3RGXA 4U08A 4NKGA 4PKIG 3OJAB 4ARNA 4R08A 4J0MA 2P1MB 1SQ0B 3WPCA 4Y61B 2JQDA 3CIGA 3VQ1A 1LTXA 2OMVA 2WQVA 3A79B 3UL9A 2A0ZA 5IJCA 2P1QB 4PQ8A 4WP6A 4QC0A 3M19A 4M7EC 5GMHA 2WQUA 2ASSB 4ARRA 4FHOA 3UL7A 4Z61C 3TSRE 4LSXA 4TZHA 4K17A 4BV4R 1OTMA 2R9UA 2ELLA 3E6JA 2WFHA 3ZYNA 4LI2A 4XGOA 4QXEA 3WN4A 4Q62A 3OJAA 3KJ4A 4RCAB 5IJBA 5AZ5A 4G8AA 4LXSA 4R09A 3E4GA 2V9TB 2XWTC 1M9LA 1M10B 1WWLA 1FO1A 4Z94G 4Z8GA 1G9UA 3G39A 3ZYIA 5GMGA 4ECOA 2XOTA 4CNMA 1GWBA 3RFJA 2O6SA 4LSCA 3VQ2A 3JB9j 4R0AA 4MN8B 4CP6A 3W3KA 1O6SA 3WPDA 3RFSA 1XKUA 1D0BA 4PSJA 3RW7A 3PMHG 3OGMB 1A4YA 4KXFB 2BEXA 4H09A 1M9SA 2Z66A 4NKHA 3W3MA 4LSAA 3W3LA 4FD0A 4R07A 4HQ1A 1XECA 2CA6A 4FCGA 1JL5A 3REZA 5CMNA 3RFEA 4R6FA 5AWCA 3ULAA 4Z79A 3RIZA 1FT8A 2Z7XB 4NZRM 4R58A 3M18A 3G3AA 1XEUA 4WYKA 1K5GC 2WQXA 4XOSA 4AY9X 4Z64C 1W8AA 3W3JA 1Z7XW 3G06A 1A9NA 4P91A 4EZGA 2Z65A 5IYXC 3G3BA 5GS0A 4FS7A 3P72A 2Z64A 4Q3IA 5FTTB 4R6JA 3E3ZA 1OOKG 3C6NB 4BSSA 1OGQA 5AWDA 3RW6A 4V2CA 2RR6A 3ULUA 2ASTB 4C2AB 2ID5A 2Z7XA 3WPFA 4CC4A 4RCWA 4GLPA 1P8VA 1YRGA 1ZIWA 1DFJI 2V70A 1FS2A 3FXIA 4GT6A 3OGLB 3WPHA 1H6UA 1KOHA 3CIYA 2OMXA 4FMZA 1M0ZA 3GOZA 3W3GA 5GMFA 3WPBA 3CVRA 1FQVA 2IFGA 4OQTA 4BSRA 4PEQB 2Z82A 1XCDA 3SB4A 3C6PB 4U7LA 3E2JA 2RA8A 1KOOA 2O6RA 1IO0A 2Z81A 4XSQA 3C6OB 2BNHA 2FT3A 5HDHA 4MQWX 1OTOA 4J4LA 1P8TA 4R6AA 4R6GA 1O6TA 1P9AG 2O6QA 4M7EA 2JE0A 3RGZA 3O6NA 3RJ0A 4B8CD 3WPEA 3ZYOA 4U06A 3UN9A 1QYYA 4LI1A 2OMUA 4NZTM 3W3NA 4KNGA 4YEBB 4P8SA 4BSUA 5B0TA 2UZYA 3BZ5A 4UFRA 2OMYA 3ZYJA 2JE1A
chains in the Genus database with same CATH topology
4CNCA 1O6VA 5LFNA 1H6TA 2OMTA 5B0NA 5IJDA 2V9SA 1DS9A 4QBZA 4V2EA 3O53A 1OZNA 2P1OB 3UL8A 4U09A 3WPIA 2WQWA 5D3IA 5HZLB 4R5CA 4AW4A 2UZXA 3ULVA 4IM6A 4LSXC 4Q3GA 2P1NB 3WPGA 1OTNA 3G04C 1DCEA 5GS2B 4ECNA 5AWBA 1K5DC 5CMPA 2Z62A 4L3AA 1U0ND 5A5CA 4FDWA 4R5DA 4CC4C 2Z63A 4CILA 3OGKB 1PGVA 4LXRA 4I6JB 2Q4GW 4KT1A 4PERA 4V2DA 3DZEA 2OMZA 2P1PB 1XWDC 2Y5QA 5B4PA 5AWAA 2OMWA 4RWTC 5GQRK 4C2BB 4L3FA 3RGXA 4U08A 4NKGA 4PKIG 3OJAB 4ARNA 4R08A 4J0MA 2P1MB 1SQ0B 3WPCA 4Y61B 2JQDA 3CIGA 3VQ1A 1LTXA 2OMVA 2WQVA 3A79B 3UL9A 2A0ZA 5IJCA 2P1QB 4PQ8A 4WP6A 4QC0A 3M19A 4M7EC 5GMHA 2WQUA 2ASSB 4ARRA 4FHOA 3UL7A 4Z61C 3TSRE 4LSXA 4TZHA 4K17A 4BV4R 1OTMA 2R9UA 2ELLA 3E6JA 2WFHA 3ZYNA 4LI2A 4XGOA 4QXEA 3WN4A 4Q62A 3OJAA 3KJ4A 4RCAB 5IJBA 5AZ5A 4G8AA 4LXSA 4R09A 3E4GA 2V9TB 2XWTC 1M9LA 1M10B 1WWLA 1FO1A 4Z94G 4Z8GA 1G9UA 3G39A 3ZYIA 5GMGA 4ECOA 2XOTA 4CNMA 1GWBA 3RFJA 2O6SA 4LSCA 3VQ2A 3JB9j 4R0AA 4MN8B 4CP6A 3W3KA 1O6SA 3WPDA 3RFSA 1XKUA 1D0BA 4PSJA 3RW7A 3PMHG 3OGMB 1A4YA 4KXFB 2BEXA 4H09A 1M9SA 2Z66A 4NKHA 3W3MA 4LSAA 3W3LA 4FD0A 4R07A 4HQ1A 1XECA 2CA6A 4FCGA 1JL5A 3REZA 5CMNA 3RFEA 4R6FA 5AWCA 3ULAA 4Z79A 3RIZA 1FT8A 2Z7XB 4R58A 3M18A 3G3AA 1XEUA 4WYKA 1K5GC 2WQXA 4XOSA 4AY9X 4Z64C 1W8AA 3W3JA 1Z7XW 3G06A 1A9NA 4P91A 4EZGA 2Z65A 5IYXC 3G3BA 5GS0A 4FS7A 3P72A 2Z64A 4Q3IA 5FTTB 4R6JA 3E3ZA 1OOKG 3C6NB 4BSSA 1OGQA 5AWDA 3RW6A 4V2CA 2RR6A 3ULUA 2ASTB 4C2AB 2ID5A 2Z7XA 3WPFA 4CC4A 4RCWA 4GLPA 1P8VA 1YRGA 1ZIWA 1DFJI 2V70A 1FS2A 3FXIA 4GT6A 3OGLB 3WPHA 1H6UA 1KOHA 3CIYA 2OMXA 4FMZA 1M0ZA 3GOZA 3W3GA 5GMFA 3WPBA 3CVRA 1FQVA 2IFGA 4OQTA 4BSRA 4PEQB 2Z82A 1XCDA 3SB4A 3C6PB 4U7LA 3E2JA 2RA8A 1KOOA 2O6RA 1IO0A 2Z81A 4XSQA 3C6OB 2BNHA 2FT3A 5HDHA 4MQWX 1OTOA 4J4LA 1P8TA 4R6AA 4R6GA 1O6TA 1P9AG 2O6QA 4M7EA 2JE0A 3RGZA 3O6NA 3RJ0A 4B8CD 3WPEA 3ZYOA 4U06A 3UN9A 1QYYA 4LI1A 2OMUA 3W3NA 4KNGA 4YEBB 4P8SA 4BSUA 5B0TA 2UZYA 3BZ5A 4UFRA 2OMYA 3ZYJA 2JE1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4CNC A;  1O6V A;  5LFN A;  1H6T A;  2OMT A;  5B0N A;  5IJD A;  2V9S A;  1DS9 A;  4QBZ A;  4V2E A;  3O53 A;  1OZN A;  2P1O B;  3UL8 A;  4U09 A;  3WPI A;  2WQW A;  5D3I A;  5HZL B;  4R5C A;  4AW4 A;  2UZX A;  3ULV A;  4IM6 A;  4LSX C;  4Q3G A;  2P1N B;  3WPG A;  1OTN A;  3G04 C;  1DCE A;  5GS2 B;  4ECN A;  5AWB A;  1K5D C;  5CMP A;  2Z62 A;  4L3A A;  1U0N D;  5A5C A;  4FDW A;  4R5D A;  4CC4 C;  2Z63 A;  4CIL A;  3OGK B;  1PGV A;  4LXR A;  4I6J B;  2Q4G W;  4KT1 A;  4PER A;  4V2D A;  3DZE A;  2OMZ A;  2P1P B;  1XWD C;  2Y5Q A;  5B4P A;  5AWA A;  2OMW A;  4RWT C;  5GQR K;  4C2B B;  4L3F A;  3RGX A;  4U08 A;  4NKG A;  4PKI G;  3OJA B;  4ARN A;  4R08 A;  4J0M A;  2P1M B;  1SQ0 B;  3WPC A;  4Y61 B;  2JQD A;  3CIG A;  3VQ1 A;  1LTX A;  2OMV A;  2WQV A;  3A79 B;  3UL9 A;  2A0Z A;  5IJC A;  2P1Q B;  4PQ8 A;  4WP6 A;  4QC0 A;  3M19 A;  4M7E C;  5GMH A;  2WQU A;  2ASS B;  4ARR A;  4FHO A;  3UL7 A;  4Z61 C;  3TSR E;  4LSX A;  4TZH A;  4K17 A;  4BV4 R;  1OTM A;  2R9U A;  2ELL A;  3E6J A;  2WFH A;  3ZYN A;  4LI2 A;  4XGO A;  4QXE A;  3WN4 A;  4Q62 A;  3OJA A;  3KJ4 A;  4RCA B;  5IJB A;  5AZ5 A;  4G8A A;  4LXS A;  4R09 A;  3E4G A;  2V9T B;  2XWT C;  1M9L A;  1M10 B;  1WWL A;  1FO1 A;  4Z94 G;  4Z8G A;  1G9U A;  3G39 A;  3ZYI A;  5GMG A;  4ECO A;  2XOT A;  4CNM A;  1GWB A;  3RFJ A;  2O6S A;  4LSC A;  3VQ2 A;  3JB9 j;  4R0A A;  4MN8 B;  4CP6 A;  3W3K A;  1O6S A;  3WPD A;  3RFS A;  1XKU A;  1D0B A;  4PSJ A;  3RW7 A;  3PMH G;  3OGM B;  1A4Y A;  4KXF B;  2BEX A;  4H09 A;  1M9S A;  2Z66 A;  4NKH A;  3W3M A;  4LSA A;  3W3L A;  4FD0 A;  4R07 A;  4HQ1 A;  1XEC A;  2CA6 A;  4FCG A;  1JL5 A;  3REZ A;  5CMN A;  3RFE A;  4R6F A;  5AWC A;  3ULA A;  4Z79 A;  3RIZ A;  1FT8 A;  2Z7X B;  4R58 A;  3M18 A;  3G3A A;  1XEU A;  4WYK A;  1K5G C;  2WQX A;  4XOS A;  4AY9 X;  4Z64 C;  1W8A A;  3W3J A;  1Z7X W;  3G06 A;  1A9N A;  4P91 A;  4EZG A;  2Z65 A;  5IYX C;  3G3B A;  5GS0 A;  4FS7 A;  3P72 A;  2Z64 A;  4Q3I A;  5FTT B;  4R6J A;  3E3Z A;  1OOK G;  3C6N B;  4BSS A;  1OGQ A;  5AWD A;  3RW6 A;  4V2C A;  2RR6 A;  3ULU A;  2AST B;  4C2A B;  2ID5 A;  2Z7X A;  3WPF A;  4CC4 A;  4RCW A;  4GLP A;  1P8V A;  1YRG A;  1ZIW A;  1DFJ I;  2V70 A;  1FS2 A;  3FXI A;  4GT6 A;  3OGL B;  3WPH A;  1H6U A;  1KOH A;  3CIY A;  2OMX A;  4FMZ A;  1M0Z A;  3GOZ A;  3W3G A;  5GMF A;  3WPB A;  3CVR A;  1FQV A;  2IFG A;  4OQT A;  4BSR A;  4PEQ B;  2Z82 A;  1XCD A;  3SB4 A;  3C6P B;  4U7L A;  3E2J A;  2RA8 A;  1KOO A;  2O6R A;  1IO0 A;  2Z81 A;  4XSQ A;  3C6O B;  2BNH A;  2FT3 A;  5HDH A;  4MQW X;  1OTO A;  4J4L A;  1P8T A;  4R6A A;  4R6G A;  1O6T A;  1P9A G;  2O6Q A;  4M7E A;  2JE0 A;  3RGZ A;  3O6N A;  3RJ0 A;  4B8C D;  3WPE A;  3ZYO A;  4U06 A;  3UN9 A;  1QYY A;  4LI1 A;  2OMU A;  3W3N A;  4KNG A;  4YEB B;  4P8S A;  4BSU A;  5B0T A;  2UZY A;  3BZ5 A;  4UFR A;  2OMY A;  3ZYJ A;  2JE1 A; 
#chains in the Genus database with same CATH topology
 4CNC A;  1O6V A;  5LFN A;  1H6T A;  2OMT A;  5B0N A;  5IJD A;  2V9S A;  1DS9 A;  4QBZ A;  4V2E A;  3O53 A;  1OZN A;  2P1O B;  3UL8 A;  4U09 A;  3WPI A;  2WQW A;  5D3I A;  5HZL B;  4R5C A;  4AW4 A;  2UZX A;  3ULV A;  4IM6 A;  4LSX C;  4Q3G A;  2P1N B;  3WPG A;  1OTN A;  3G04 C;  1DCE A;  5GS2 B;  4ECN A;  5AWB A;  1K5D C;  5CMP A;  2Z62 A;  4L3A A;  1U0N D;  5A5C A;  4FDW A;  4R5D A;  4CC4 C;  2Z63 A;  4CIL A;  3OGK B;  1PGV A;  4LXR A;  4I6J B;  2Q4G W;  4KT1 A;  4PER A;  4V2D A;  3DZE A;  2OMZ A;  2P1P B;  1XWD C;  2Y5Q A;  5B4P A;  5AWA A;  2OMW A;  4RWT C;  5GQR K;  4C2B B;  4L3F A;  3RGX A;  4U08 A;  4NKG A;  4PKI G;  3OJA B;  4ARN A;  4R08 A;  4J0M A;  2P1M B;  1SQ0 B;  3WPC A;  4Y61 B;  2JQD A;  3CIG A;  3VQ1 A;  1LTX A;  2OMV A;  2WQV A;  3A79 B;  3UL9 A;  2A0Z A;  5IJC A;  2P1Q B;  4PQ8 A;  4WP6 A;  4QC0 A;  3M19 A;  4M7E C;  5GMH A;  2WQU A;  2ASS B;  4ARR A;  4FHO A;  3UL7 A;  4Z61 C;  3TSR E;  4LSX A;  4TZH A;  4K17 A;  4BV4 R;  1OTM A;  2R9U A;  2ELL A;  3E6J A;  2WFH A;  3ZYN A;  4LI2 A;  4XGO A;  4QXE A;  3WN4 A;  4Q62 A;  3OJA A;  3KJ4 A;  4RCA B;  5IJB A;  5AZ5 A;  4G8A A;  4LXS A;  4R09 A;  3E4G A;  2V9T B;  2XWT C;  1M9L A;  1M10 B;  1WWL A;  1FO1 A;  4Z94 G;  4Z8G A;  1G9U A;  3G39 A;  3ZYI A;  5GMG A;  4ECO A;  2XOT A;  4CNM A;  1GWB A;  3RFJ A;  2O6S A;  4LSC A;  3VQ2 A;  3JB9 j;  4R0A A;  4MN8 B;  4CP6 A;  3W3K A;  1O6S A;  3WPD A;  3RFS A;  1XKU A;  1D0B A;  4PSJ A;  3RW7 A;  3PMH G;  3OGM B;  1A4Y A;  4KXF B;  2BEX A;  4H09 A;  1M9S A;  2Z66 A;  4NKH A;  3W3M A;  4LSA A;  3W3L A;  4FD0 A;  4R07 A;  4HQ1 A;  1XEC A;  2CA6 A;  4FCG A;  1JL5 A;  3REZ A;  5CMN A;  3RFE A;  4R6F A;  5AWC A;  3ULA A;  4Z79 A;  3RIZ A;  1FT8 A;  2Z7X B;  4NZR M;  4R58 A;  3M18 A;  3G3A A;  1XEU A;  4WYK A;  1K5G C;  2WQX A;  4XOS A;  4AY9 X;  4Z64 C;  1W8A A;  3W3J A;  1Z7X W;  3G06 A;  1A9N A;  4P91 A;  4EZG A;  2Z65 A;  5IYX C;  3G3B A;  5GS0 A;  4FS7 A;  3P72 A;  2Z64 A;  4Q3I A;  5FTT B;  4R6J A;  3E3Z A;  1OOK G;  3C6N B;  4BSS A;  1OGQ A;  5AWD A;  3RW6 A;  4V2C A;  2RR6 A;  3ULU A;  2AST B;  4C2A B;  2ID5 A;  2Z7X A;  3WPF A;  4CC4 A;  4RCW A;  4GLP A;  1P8V A;  1YRG A;  1ZIW A;  1DFJ I;  2V70 A;  1FS2 A;  3FXI A;  4GT6 A;  3OGL B;  3WPH A;  1H6U A;  1KOH A;  3CIY A;  2OMX A;  4FMZ A;  1M0Z A;  3GOZ A;  3W3G A;  5GMF A;  3WPB A;  3CVR A;  1FQV A;  2IFG A;  4OQT A;  4BSR A;  4PEQ B;  2Z82 A;  1XCD A;  3SB4 A;  3C6P B;  4U7L A;  3E2J A;  2RA8 A;  1KOO A;  2O6R A;  1IO0 A;  2Z81 A;  4XSQ A;  3C6O B;  2BNH A;  2FT3 A;  5HDH A;  4MQW X;  1OTO A;  4J4L A;  1P8T A;  4R6A A;  4R6G A;  1O6T A;  1P9A G;  2O6Q A;  4M7E A;  2JE0 A;  3RGZ A;  3O6N A;  3RJ0 A;  4B8C D;  3WPE A;  3ZYO A;  4U06 A;  3UN9 A;  1QYY A;  4LI1 A;  2OMU A;  4NZT M;  3W3N A;  4KNG A;  4YEB B;  4P8S A;  4BSU A;  5B0T A;  2UZY A;  3BZ5 A;  4UFR A;  2OMY A;  3ZYJ A;  2JE1 A; 
#chains in the Genus database with same CATH homology
 4CNC A;  1O6V A;  5LFN A;  1H6T A;  2OMT A;  5B0N A;  5IJD A;  2V9S A;  1DS9 A;  4QBZ A;  4V2E A;  3O53 A;  1OZN A;  2P1O B;  3UL8 A;  4U09 A;  3WPI A;  2WQW A;  5D3I A;  5HZL B;  4R5C A;  4AW4 A;  2UZX A;  3ULV A;  4IM6 A;  4LSX C;  4Q3G A;  2P1N B;  3WPG A;  1OTN A;  3G04 C;  1DCE A;  5GS2 B;  4ECN A;  5AWB A;  1K5D C;  5CMP A;  2Z62 A;  4L3A A;  1U0N D;  5A5C A;  4FDW A;  4R5D A;  4CC4 C;  2Z63 A;  4CIL A;  3OGK B;  1PGV A;  4LXR A;  4I6J B;  2Q4G W;  4KT1 A;  4PER A;  4V2D A;  3DZE A;  2OMZ A;  2P1P B;  1XWD C;  2Y5Q A;  5B4P A;  5AWA A;  2OMW A;  4RWT C;  5GQR K;  4C2B B;  4L3F A;  3RGX A;  4U08 A;  4NKG A;  4PKI G;  3OJA B;  4ARN A;  4R08 A;  4J0M A;  2P1M B;  1SQ0 B;  3WPC A;  4Y61 B;  2JQD A;  3CIG A;  3VQ1 A;  1LTX A;  2OMV A;  2WQV A;  3A79 B;  3UL9 A;  2A0Z A;  5IJC A;  2P1Q B;  4PQ8 A;  4WP6 A;  4QC0 A;  3M19 A;  4M7E C;  5GMH A;  2WQU A;  2ASS B;  4ARR A;  4FHO A;  3UL7 A;  4Z61 C;  3TSR E;  4LSX A;  4TZH A;  4K17 A;  4BV4 R;  1OTM A;  2R9U A;  2ELL A;  3E6J A;  2WFH A;  3ZYN A;  4LI2 A;  4XGO A;  4QXE A;  3WN4 A;  4Q62 A;  3OJA A;  3KJ4 A;  4RCA B;  5IJB A;  5AZ5 A;  4G8A A;  4LXS A;  4R09 A;  3E4G A;  2V9T B;  2XWT C;  1M9L A;  1M10 B;  1WWL A;  1FO1 A;  4Z94 G;  4Z8G A;  1G9U A;  3G39 A;  3ZYI A;  5GMG A;  4ECO A;  2XOT A;  4CNM A;  1GWB A;  3RFJ A;  2O6S A;  4LSC A;  3VQ2 A;  3JB9 j;  4R0A A;  4MN8 B;  4CP6 A;  3W3K A;  1O6S A;  3WPD A;  3RFS A;  1XKU A;  1D0B A;  4PSJ A;  3RW7 A;  3PMH G;  3OGM B;  1A4Y A;  4KXF B;  2BEX A;  4H09 A;  1M9S A;  2Z66 A;  4NKH A;  3W3M A;  4LSA A;  3W3L A;  4FD0 A;  4R07 A;  4HQ1 A;  1XEC A;  2CA6 A;  4FCG A;  1JL5 A;  3REZ A;  5CMN A;  3RFE A;  4R6F A;  5AWC A;  3ULA A;  4Z79 A;  3RIZ A;  1FT8 A;  2Z7X B;  4R58 A;  3M18 A;  3G3A A;  1XEU A;  4WYK A;  1K5G C;  2WQX A;  4XOS A;  4AY9 X;  4Z64 C;  1W8A A;  3W3J A;  1Z7X W;  3G06 A;  1A9N A;  4P91 A;  4EZG A;  2Z65 A;  5IYX C;  3G3B A;  5GS0 A;  4FS7 A;  3P72 A;  2Z64 A;  4Q3I A;  5FTT B;  4R6J A;  3E3Z A;  1OOK G;  3C6N B;  4BSS A;  1OGQ A;  5AWD A;  3RW6 A;  4V2C A;  2RR6 A;  3ULU A;  2AST B;  4C2A B;  2ID5 A;  2Z7X A;  3WPF A;  4CC4 A;  4RCW A;  4GLP A;  1P8V A;  1YRG A;  1ZIW A;  1DFJ I;  2V70 A;  1FS2 A;  3FXI A;  4GT6 A;  3OGL B;  3WPH A;  1H6U A;  1KOH A;  3CIY A;  2OMX A;  4FMZ A;  1M0Z A;  3GOZ A;  3W3G A;  5GMF A;  3WPB A;  3CVR A;  1FQV A;  2IFG A;  4OQT A;  4BSR A;  4PEQ B;  2Z82 A;  1XCD A;  3SB4 A;  3C6P B;  4U7L A;  3E2J A;  2RA8 A;  1KOO A;  2O6R A;  1IO0 A;  2Z81 A;  4XSQ A;  3C6O B;  2BNH A;  2FT3 A;  5HDH A;  4MQW X;  1OTO A;  4J4L A;  1P8T A;  4R6A A;  4R6G A;  1O6T A;  1P9A G;  2O6Q A;  4M7E A;  2JE0 A;  3RGZ A;  3O6N A;  3RJ0 A;  4B8C D;  3WPE A;  3ZYO A;  4U06 A;  3UN9 A;  1QYY A;  4LI1 A;  2OMU A;  3W3N A;  4KNG A;  4YEB B;  4P8S A;  4BSU A;  5B0T A;  2UZY A;  3BZ5 A;  4UFR A;  2OMY A;  3ZYJ A;  2JE1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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