4R5QA

Crystal structure and nuclease activity of the crispr-associated cas4 protein pcal_0546 from pyrobaculum calidifontis containing a [2fe-2s] cluster
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
215
structure length
215
Chain Sequence
FNGMELLSPKPLCSVVNCEDLEKLDHVSALNELRREQEIFKLLPGIYAHRYDFRRVSPSIINDFEYCPRLLWVQHKLGLKLLSEKSVVSIIRGRILHERYERLLSQYENVVAEYKVEIGDLVGVVDLVIKRGGEYIPVEIKTGFSKEAHKTQLQIYISMLKARFGYLVYRNHVEVVHRNDAALDVLKKIREILSAREAPPAKCNSCIFKPICKNL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords CRISPR-associated exonuclease, Cas4 family
publication title Crystal structure and nuclease activity of the CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis containing a [2Fe-2S] cluster
rcsb
source organism Pyrobaculum calidifontis jcm 11548
total genus 58
structure length 215
sequence length 215
ec nomenclature ec 3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
pdb deposition date 2014-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01930 Cas_Cas4 Domain of unknown function DUF83
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 4r5qA00
4WUZA 1W36B 4IC1A 4R5QA 4CEJA 3SLPA 3K70B 3SZ5A 3SM4A 5LD2B 3U44A 4CEIA 4CEHA 3SYYA 3L0AA 3SZ4A 3U4QA 3K93A 1AVQA 3H4RA
chains in the Genus database with same CATH superfamily
4WUZA 1MROC 3M2UC 3M2RC 1E6YC 1W36B 4IC1A 5A8RC 4R5QA 4CEJA 3M30C 3SLPA 3M32C 1HBNC 3K70B 3SZ5A 1HBOC 3SM4A 5G0RC 5LD2B 5A8WC 3U44A 4CEIA 4CEHA 3SYYA 3POTC 1E6VC 1HBUC 5A8KC 3M2VC 1HBMC 3L0AA 3SZ4A 3U4QA 3M1VC 3SQGC 3K93A 1AVQA 5A0YC 3H4RA
chains in the Genus database with same CATH topology
4WUZA 1W36B 4IC1A 4R5QA 4CEJA 3SLPA 3K70B 3SZ5A 3SM4A 5LD2B 3U44A 4CEIA 4CEHA 3SYYA 3L0AA 3SZ4A 3U4QA 3K93A 1AVQA 3H4RA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4WUZ A;  1W36 B;  4IC1 A;  4R5Q A;  4CEJ A;  3SLP A;  3K70 B;  3SZ5 A;  3SM4 A;  5LD2 B;  3U44 A;  4CEI A;  4CEH A;  3SYY A;  3L0A A;  3SZ4 A;  3U4Q A;  3K93 A;  1AVQ A;  3H4R A; 
#chains in the Genus database with same CATH topology
 4WUZ A;  1MRO C;  3M2U C;  3M2R C;  1E6Y C;  1W36 B;  4IC1 A;  5A8R C;  4R5Q A;  4CEJ A;  3M30 C;  3SLP A;  3M32 C;  1HBN C;  3K70 B;  3SZ5 A;  1HBO C;  3SM4 A;  5G0R C;  5LD2 B;  5A8W C;  3U44 A;  4CEI A;  4CEH A;  3SYY A;  3POT C;  1E6V C;  1HBU C;  5A8K C;  3M2V C;  1HBM C;  3L0A A;  3SZ4 A;  3U4Q A;  3M1V C;  3SQG C;  3K93 A;  1AVQ A;  5A0Y C;  3H4R A; 
#chains in the Genus database with same CATH homology
 4WUZ A;  1W36 B;  4IC1 A;  4R5Q A;  4CEJ A;  3SLP A;  3K70 B;  3SZ5 A;  3SM4 A;  5LD2 B;  3U44 A;  4CEI A;  4CEH A;  3SYY A;  3L0A A;  3SZ4 A;  3U4Q A;  3K93 A;  1AVQ A;  3H4R A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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