4R5QA

Crystal structure and nuclease activity of the crispr-associated cas4 protein pcal_0546 from pyrobaculum calidifontis containing a [2fe-2s] cluster
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
215
structure length
215
Chain Sequence
FNGMELLSPKPLCSVVNCEDLEKLDHVSALNELRREQEIFKLLPGIYAHRYDFRRVSPSIINDFEYCPRLLWVQHKLGLKLLSEKSVVSIIRGRILHERYERLLSQYENVVAEYKVEIGDLVGVVDLVIKRGGEYIPVEIKTGFSKEAHKTQLQIYISMLKARFGYLVYRNHVEVVHRNDAALDVLKKIREILSAREAPPAKCNSCIFKPICKNL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and nuclease activity of the CRISPR-associated Cas4 protein Pcal_0546 from Pyrobaculum calidifontis containing a [2Fe-2S] cluster
rcsb
molecule tags Hydrolase
source organism Pyrobaculum calidifontis jcm 11548
molecule keywords CRISPR-associated exonuclease, Cas4 family
total genus 58
structure length 215
sequence length 215
ec nomenclature ec 3.1.12.1: 5' to 3' exodeoxyribonuclease (nucleoside 3'-phosphate-forming).
pdb deposition date 2014-08-21

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01930 Cas_Cas4 Domain of unknown function DUF83
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.320.10 Alpha Beta Alpha-Beta Complex Lambda Exonuclease; Chain A Lambda Exonuclease; Chain A 4r5qA00
3H4RA 4CEIA 1W36B 3K70B 3U44A 4CEJA 4CEHA 4IC1A 3K93A 4WUZA 3SZ5A 3SLPA 3SYYA 1AVQA 4R5QA 3L0AA 5LD2B 3SM4A 3U4QA 3SZ4A
chains in the Genus database with same CATH superfamily
5A8RC 3M2UC 3POTC 3H4RA 1W36B 4CEIA 5A8KC 1E6VC 3K70B 3U44A 3SZ4A 4CEJA 4CEHA 3M30C 4IC1A 1MROC 1E6YC 3SQGC 3M2RC 1HBMC 3K93A 4WUZA 3SZ5A 3SLPA 1HBOC 3SYYA 3M1VC 1AVQA 5A8WC 4R5QA 3L0AA 5A0YC 1HBUC 5G0RC 3M32C 5LD2B 1HBNC 3SM4A 3U4QA 3M2VC
chains in the Genus database with same CATH topology
3H4RA 4CEIA 1W36B 3K70B 3U44A 4CEJA 4CEHA 4IC1A 3K93A 4WUZA 3SZ5A 3SLPA 3SYYA 1AVQA 4R5QA 3L0AA 5LD2B 3SM4A 3U4QA 3SZ4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3H4R A;  4CEI A;  1W36 B;  3K70 B;  3U44 A;  4CEJ A;  4CEH A;  4IC1 A;  3K93 A;  4WUZ A;  3SZ5 A;  3SLP A;  3SYY A;  1AVQ A;  4R5Q A;  3L0A A;  5LD2 B;  3SM4 A;  3U4Q A;  3SZ4 A; 
#chains in the Genus database with same CATH topology
 5A8R C;  3M2U C;  3POT C;  3H4R A;  1W36 B;  4CEI A;  5A8K C;  1E6V C;  3K70 B;  3U44 A;  3SZ4 A;  4CEJ A;  4CEH A;  3M30 C;  4IC1 A;  1MRO C;  1E6Y C;  3SQG C;  3M2R C;  1HBM C;  3K93 A;  4WUZ A;  3SZ5 A;  3SLP A;  1HBO C;  3SYY A;  3M1V C;  1AVQ A;  5A8W C;  4R5Q A;  3L0A A;  5A0Y C;  1HBU C;  5G0R C;  3M32 C;  5LD2 B;  1HBN C;  3SM4 A;  3U4Q A;  3M2V C; 
#chains in the Genus database with same CATH homology
 3H4R A;  4CEI A;  1W36 B;  3K70 B;  3U44 A;  4CEJ A;  4CEH A;  4IC1 A;  3K93 A;  4WUZ A;  3SZ5 A;  3SLP A;  3SYY A;  1AVQ A;  4R5Q A;  3L0A A;  5LD2 B;  3SM4 A;  3U4Q A;  3SZ4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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