4RRIA

K116m mutant of n-terminal editing domain of threonyl-trna synthetase from aeropyrum pernix with l-thr3aa
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
136
structure length
136
Chain Sequence
MRLLYLHADRFEYKTVKPALKNPPDPPGEASFGEALVVFTTVEDGDGPQTVMYAASDIASHSSRLKVTTVILYPYAHLSSRLAKPMAAHKRLIELEGALRTKFPGHVHRAPFGWYMSFSIACKGHPLAELSRSFTE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Ligase
molecule keywords Probable threonine--tRNA ligase 2
publication title Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.
pubmed doi rcsb
source organism Aeropyrum pernix
total genus 38
structure length 136
sequence length 136
ec nomenclature ec 6.1.1.3: Threonine--tRNA ligase.
pdb deposition date 2014-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF08915 tRNA-Thr_ED Archaea-specific editing domain of threonyl-tRNA synthetase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.80.10 Alpha Beta 3-Layer(bba) Sandwich D-tyrosyl-trna(Tyr) Deacylase; Chain: A; D-tyrosyl-trna(Tyr) Deacylase; Chain: A; 4rriA01
4RRCA 4RR7A 4RRIA 4S0LA 4RR6A 3KNPA 1J7GA 2OKVA 3PD2A 3KO4A 1JKEA 4RRFA 3KO3A 3LMVA 2HL0A 4RRMA 4RRJA 3KOBA 3KNFA 4S0JA 4RRLA 3PD4A 2DBOA 4RRQA 1TC5A 4NBJA 4RR8A 2HL1A 4RRBA 4RRAA 4RRGA 3KODA 5J61A 3KOCA 4S0IA 3KO5A 3LMUA 4RRDA 2HKZA 4RRKA 3KO7A 4RRRA 4S03A 4S0KA 4S02A 2HL2A 3PD3A 4RR9A 4NBIA 3LMTA 4RRHA 1Y2QA 3KO9A 3PD5A
chains in the Genus database with same CATH superfamily
1W5DA 4RR7A 2EXAA 2Y59A 1JKEA 4B4XA 3KNFA 4RRLA 3PD4A 1TC5A 4NBJA 2XK1A 2HL1A 4RRBA 3KODA 4BENA 2Y55A 4RRDA 1W79A 5CECA 4RRKA 3PD3A 4S0LA 1J7GA 3A3FA 2EX8A 4RRJA 4B4ZA 5CERA 2DBOA 3A3EA 4RR8A 5CEDA 2EX6A 4RRAA 3V39A 3LMUA 4S0KA 4S02A 3LMTA 3KO9A 3PD5A 4RRCA 4RR6A 3PD2A 4RRHA 3ZCZA 3KO3A 2HL0A 2J9PA 3KOBA 3ZVTA 2EX9A 4RRQA 2VGJA 2EX2A 2EXBA 3KO7A 4RRRA 4S03A 2HL2A 2XLNA 4NBIA 4RRIA 5CEBA 3KNPA 2VGKA 2OKVA 3KO4A 4RRFA 3LMVA 3A3IA 4S0JA 3A3DA 3ZVWA 4RRGA 1W8YA 5J61A 1W8QA 2WKEA 3KOCA 4S0IA 3KO5A 2HKZA 2XDMA 4RR9A 2Y4AA 4RRMA 1Y2QA
chains in the Genus database with same CATH topology
1W5DA 4RR7A 2EXAA 2Y59A 1JKEA 4B4XA 3KNFA 4RRLA 3PD4A 1TC5A 4NBJA 2XK1A 2HL1A 4RRBA 3KODA 4BENA 2Y55A 4RRDA 1W79A 5CECA 4RRKA 3PD3A 4S0LA 1J7GA 3A3FA 2EX8A 4RRJA 4B4ZA 5CERA 2DBOA 3A3EA 4RR8A 5CEDA 2EX6A 4RRAA 3V39A 3LMUA 4S0KA 4S02A 3LMTA 3KO9A 3PD5A 4RRCA 4RR6A 3PD2A 4RRHA 3ZCZA 3KO3A 2HL0A 2J9PA 3KOBA 3ZVTA 2EX9A 4RRQA 2VGJA 2EX2A 2EXBA 3KO7A 4RRRA 4S03A 2HL2A 2XLNA 4NBIA 4RRIA 5CEBA 3KNPA 2VGKA 2OKVA 3KO4A 4RRFA 3LMVA 3A3IA 4S0JA 3A3DA 3ZVWA 4RRGA 1W8YA 5J61A 1W8QA 2WKEA 3KOCA 4S0IA 3KO5A 2HKZA 2XDMA 4RR9A 2Y4AA 4RRMA 1Y2QA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4RRC A;  4RR7 A;  4RRI A;  4S0L A;  4RR6 A;  3KNP A;  1J7G A;  2OKV A;  3PD2 A;  3KO4 A;  1JKE A;  4RRF A;  3KO3 A;  3LMV A;  2HL0 A;  4RRM A;  4RRJ A;  3KOB A;  3KNF A;  4S0J A;  4RRL A;  3PD4 A;  2DBO A;  4RRQ A;  1TC5 A;  4NBJ A;  4RR8 A;  2HL1 A;  4RRB A;  4RRA A;  4RRG A;  3KOD A;  5J61 A;  3KOC A;  4S0I A;  3KO5 A;  3LMU A;  4RRD A;  2HKZ A;  4RRK A;  3KO7 A;  4RRR A;  4S03 A;  4S0K A;  4S02 A;  2HL2 A;  3PD3 A;  4RR9 A;  4NBI A;  3LMT A;  4RRH A;  1Y2Q A;  3KO9 A;  3PD5 A; 
#chains in the Genus database with same CATH topology
 1W5D A;  4RR7 A;  2EXA A;  2Y59 A;  1JKE A;  4B4X A;  3KNF A;  4RRL A;  3PD4 A;  1TC5 A;  4NBJ A;  2XK1 A;  2HL1 A;  4RRB A;  3KOD A;  4BEN A;  2Y55 A;  4RRD A;  1W79 A;  5CEC A;  4RRK A;  3PD3 A;  4S0L A;  1J7G A;  3A3F A;  2EX8 A;  4RRJ A;  4B4Z A;  5CER A;  2DBO A;  3A3E A;  4RR8 A;  5CED A;  2EX6 A;  4RRA A;  3V39 A;  3LMU A;  4S0K A;  4S02 A;  3LMT A;  3KO9 A;  3PD5 A;  4RRC A;  4RR6 A;  3PD2 A;  4RRH A;  3ZCZ A;  3KO3 A;  2HL0 A;  2J9P A;  3KOB A;  3ZVT A;  2EX9 A;  4RRQ A;  2VGJ A;  2EX2 A;  2EXB A;  3KO7 A;  4RRR A;  4S03 A;  2HL2 A;  2XLN A;  4NBI A;  4RRI A;  5CEB A;  3KNP A;  2VGK A;  2OKV A;  3KO4 A;  4RRF A;  3LMV A;  3A3I A;  4S0J A;  3A3D A;  3ZVW A;  4RRG A;  1W8Y A;  5J61 A;  1W8Q A;  2WKE A;  3KOC A;  4S0I A;  3KO5 A;  2HKZ A;  2XDM A;  4RR9 A;  2Y4A A;  4RRM A;  1Y2Q A; 
#chains in the Genus database with same CATH homology
 1W5D A;  4RR7 A;  2EXA A;  2Y59 A;  1JKE A;  4B4X A;  3KNF A;  4RRL A;  3PD4 A;  1TC5 A;  4NBJ A;  2XK1 A;  2HL1 A;  4RRB A;  3KOD A;  4BEN A;  2Y55 A;  4RRD A;  1W79 A;  5CEC A;  4RRK A;  3PD3 A;  4S0L A;  1J7G A;  3A3F A;  2EX8 A;  4RRJ A;  4B4Z A;  5CER A;  2DBO A;  3A3E A;  4RR8 A;  5CED A;  2EX6 A;  4RRA A;  3V39 A;  3LMU A;  4S0K A;  4S02 A;  3LMT A;  3KO9 A;  3PD5 A;  4RRC A;  4RR6 A;  3PD2 A;  4RRH A;  3ZCZ A;  3KO3 A;  2HL0 A;  2J9P A;  3KOB A;  3ZVT A;  2EX9 A;  4RRQ A;  2VGJ A;  2EX2 A;  2EXB A;  3KO7 A;  4RRR A;  4S03 A;  2HL2 A;  2XLN A;  4NBI A;  4RRI A;  5CEB A;  3KNP A;  2VGK A;  2OKV A;  3KO4 A;  4RRF A;  3LMV A;  3A3I A;  4S0J A;  3A3D A;  3ZVW A;  4RRG A;  1W8Y A;  5J61 A;  1W8Q A;  2WKE A;  3KOC A;  4S0I A;  3KO5 A;  2HKZ A;  2XDM A;  4RR9 A;  2Y4A A;  4RRM A;  1Y2Q A; 
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similar chains in the pdb database (?% sequence similarity)

 
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