4TW1A

Crystal structure of the octameric pore complex of the staphylococcus aureus bi-component toxin lukgh
Total Genus 59
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
59
sequence length
290
structure length
281
Chain Sequence
GDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHNVKFVKVLND
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Toxin
molecule keywords Possible leukocidin subunit
publication title Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 59
structure length 281
sequence length 290
chains with identical sequence C, E, G, I, K, M, O
ec nomenclature
pdb deposition date 2014-06-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4tw1A00
3B07A 2QK7B 4P1YA 3M4EA 4I0NA 3M4DA 1PVLA 4U6VA 2YGTA 4P1XB 3ROHA 3M3RA 4IYTA 3LKFA 4IYAA 5K59C 4YHDA 7AHLA 2QK7A 4H56A 1T5RA 4IYCA 4P1YB 4TW1B 3B07B 3ANZA 3O44A 2LKFA 4J0OA 4P24A 5K59A 3M2LA 4IDJA 4P1XA 4Q7GA 1LKFA 4IZLA 4TW1A
chains in the Genus database with same CATH superfamily
3B07A 2QK7B 4P1YA 3M4EA 4I0NA 3M4DA 1PVLA 4U6VA 2YGTA 4P1XB 3ROHA 3M3RA 4IYTA 3LKFA 4IYAA 5K59C 4YHDA 7AHLA 2QK7A 4H56A 1T5RA 4IYCA 4P1YB 4TW1B 3B07B 3ANZA 3O44A 2LKFA 4J0OA 4P24A 5K59A 3M2LA 4IDJA 4P1XA 4Q7GA 4TW1A 1LKFA 4IZLA 1XEZA
chains in the Genus database with same CATH topology
3B07A 2QK7B 4P1YA 3M4EA 4I0NA 3M4DA 1PVLA 4U6VA 2YGTA 4P1XB 3ROHA 3M3RA 4IYTA 3LKFA 4IYAA 5K59C 4YHDA 7AHLA 2QK7A 4H56A 1T5RA 4IYCA 4P1YB 4TW1B 3B07B 3ANZA 3O44A 2LKFA 4J0OA 4P24A 5K59A 3M2LA 4IDJA 4P1XA 4Q7GA 1LKFA 4IZLA 4TW1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3B07 A;  2QK7 B;  4P1Y A;  3M4E A;  4I0N A;  3M4D A;  1PVL A;  4U6V A;  2YGT A;  4P1X B;  3ROH A;  3M3R A;  4IYT A;  3LKF A;  4IYA A;  5K59 C;  4YHD A;  7AHL A;  2QK7 A;  4H56 A;  1T5R A;  4IYC A;  4P1Y B;  4TW1 B;  3B07 B;  3ANZ A;  3O44 A;  2LKF A;  4J0O A;  4P24 A;  5K59 A;  3M2L A;  4IDJ A;  4P1X A;  4Q7G A;  1LKF A;  4IZL A;  4TW1 A; 
#chains in the Genus database with same CATH topology
 3B07 A;  2QK7 B;  4P1Y A;  3M4E A;  4I0N A;  3M4D A;  1PVL A;  4U6V A;  2YGT A;  4P1X B;  3ROH A;  3M3R A;  4IYT A;  3LKF A;  4IYA A;  5K59 C;  4YHD A;  7AHL A;  2QK7 A;  4H56 A;  1T5R A;  4IYC A;  4P1Y B;  4TW1 B;  3B07 B;  3ANZ A;  3O44 A;  2LKF A;  4J0O A;  4P24 A;  5K59 A;  3M2L A;  4IDJ A;  4P1X A;  4Q7G A;  4TW1 A;  1LKF A;  4IZL A;  1XEZ A; 
#chains in the Genus database with same CATH homology
 3B07 A;  2QK7 B;  4P1Y A;  3M4E A;  4I0N A;  3M4D A;  1PVL A;  4U6V A;  2YGT A;  4P1X B;  3ROH A;  3M3R A;  4IYT A;  3LKF A;  4IYA A;  5K59 C;  4YHD A;  7AHL A;  2QK7 A;  4H56 A;  1T5R A;  4IYC A;  4P1Y B;  4TW1 B;  3B07 B;  3ANZ A;  3O44 A;  2LKF A;  4J0O A;  4P24 A;  5K59 A;  3M2L A;  4IDJ A;  4P1X A;  4Q7G A;  1LKF A;  4IZL A;  4TW1 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...