4TW1B

Crystal structure of the octameric pore complex of the staphylococcus aureus bi-component toxin lukgh
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
289
structure length
282
Chain Sequence
TAPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Possible leukocidin subunit
publication title Structure-Function Analysis of Heterodimer Formation, Oligomerization, and Receptor Binding of the Staphylococcus aureus Bi-component Toxin LukGH.
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 63
structure length 282
sequence length 289
chains with identical sequence D, F, H, J, L, N, P
ec nomenclature
pdb deposition date 2014-06-29
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4tw1B00
2QK7B 3O44A 4H56A 4J0OA 3ROHA 4U6VA 4P1YA 5K59C 4IYAA 2YGTA 3M2LA 4P1YB 4P1XA 4YHDA 7AHLA 3M3RA 4IYTA 4P24A 4Q7GA 4I0NA 3B07A 4IYCA 4P1XB 1LKFA 4IDJA 4TW1A 2LKFA 1T5RA 3B07B 3LKFA 3ANZA 3M4EA 4TW1B 4IZLA 1PVLA 2QK7A 5K59A 3M4DA
chains in the Genus database with same CATH superfamily
2QK7B 3O44A 4H56A 4J0OA 3ROHA 4U6VA 4P1YA 5K59C 4IYAA 2YGTA 3M2LA 4P1YB 4P1XA 4YHDA 7AHLA 1XEZA 3M3RA 4IYTA 4P24A 4Q7GA 4I0NA 3B07A 4IYCA 4P1XB 1LKFA 4IDJA 4TW1A 2LKFA 1T5RA 3B07B 3LKFA 3ANZA 3M4EA 4TW1B 4IZLA 1PVLA 2QK7A 5K59A 3M4DA
chains in the Genus database with same CATH topology
2QK7B 3O44A 4H56A 4J0OA 3ROHA 4U6VA 4P1YA 5K59C 4IYAA 2YGTA 3M2LA 4P1YB 4P1XA 4YHDA 7AHLA 3M3RA 4IYTA 4P24A 4Q7GA 4I0NA 3B07A 4IYCA 4P1XB 1LKFA 4IDJA 4TW1A 2LKFA 1T5RA 3B07B 3LKFA 3ANZA 3M4EA 4TW1B 4IZLA 1PVLA 2QK7A 5K59A 3M4DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QK7 B;  3O44 A;  4H56 A;  4J0O A;  3ROH A;  4U6V A;  4P1Y A;  5K59 C;  4IYA A;  2YGT A;  3M2L A;  4P1Y B;  4P1X A;  4YHD A;  7AHL A;  3M3R A;  4IYT A;  4P24 A;  4Q7G A;  4I0N A;  3B07 A;  4IYC A;  4P1X B;  1LKF A;  4IDJ A;  4TW1 A;  2LKF A;  1T5R A;  3B07 B;  3LKF A;  3ANZ A;  3M4E A;  4TW1 B;  4IZL A;  1PVL A;  2QK7 A;  5K59 A;  3M4D A; 
#chains in the Genus database with same CATH topology
 2QK7 B;  3O44 A;  4H56 A;  4J0O A;  3ROH A;  4U6V A;  4P1Y A;  5K59 C;  4IYA A;  2YGT A;  3M2L A;  4P1Y B;  4P1X A;  4YHD A;  7AHL A;  1XEZ A;  3M3R A;  4IYT A;  4P24 A;  4Q7G A;  4I0N A;  3B07 A;  4IYC A;  4P1X B;  1LKF A;  4IDJ A;  4TW1 A;  2LKF A;  1T5R A;  3B07 B;  3LKF A;  3ANZ A;  3M4E A;  4TW1 B;  4IZL A;  1PVL A;  2QK7 A;  5K59 A;  3M4D A; 
#chains in the Genus database with same CATH homology
 2QK7 B;  3O44 A;  4H56 A;  4J0O A;  3ROH A;  4U6V A;  4P1Y A;  5K59 C;  4IYA A;  2YGT A;  3M2L A;  4P1Y B;  4P1X A;  4YHD A;  7AHL A;  3M3R A;  4IYT A;  4P24 A;  4Q7G A;  4I0N A;  3B07 A;  4IYC A;  4P1X B;  1LKF A;  4IDJ A;  4TW1 A;  2LKF A;  1T5R A;  3B07 B;  3LKF A;  3ANZ A;  3M4E A;  4TW1 B;  4IZL A;  1PVL A;  2QK7 A;  5K59 A;  3M4D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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