4UI2D

Crystal structure of the ternary rgmb-bmp2-neo1 complex
Total Genus 36
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
36
sequence length
156
structure length
156
Chain Sequence
PHLRTFKDNFQTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHGCTDQKVYQAVTDDLPAAFVDGTTSGGDSDAKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPEDLAMSYEESQDLQLCVNGCPLSERIDD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords NEOGENIN
publication title Repulsive Guidance Molecule is a Structural Bridge between Neogenin and Bone Morphogenetic Protein.
pubmed doi rcsb
source organism Homo sapiens
total genus 36
structure length 156
sequence length 156
ec nomenclature
pdb deposition date 2015-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
D PF06534 RGM_C Repulsive guidance molecule (RGM) C-terminus
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.1000.10 Alpha Beta 3-Layer(aba) Sandwich Protein Transport Mog1p; Chain A Mog1/PsbP, alpha/beta/alpha sandwich 4ui2D00
1TU1A 1JHSA 4RTIA 3JCUP 2XB3A 3V7BA 4BQ6D 4RTHA 1V2BA 3HLZA 3LYDA 4UI2D 4BQ8C 2VU4A 1EQ6A 2LNJA
chains in the Genus database with same CATH superfamily
1JHSA 4RTIA 4RTHA 1V2BA 1EQ6A 3JCUP 3NR5A 4LUQC 3LYDA 4N88B 3BCYA 1VR8A 4L9HA 4L9CA 4ESQA 2XB3A 3V7BA 4BQ6D 4UI2D 4BQ8C 2VU4A 4N7SB 1TU1A 4M5FB 4N80B 4OUHA 2VT8A 3HLZA 3WA5B 2LNJA
chains in the Genus database with same CATH topology
1TU1A 1JHSA 4RTIA 3JCUP 2XB3A 3V7BA 4BQ6D 4RTHA 1V2BA 3HLZA 3LYDA 4UI2D 4BQ8C 2VU4A 1EQ6A 2LNJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TU1 A;  1JHS A;  4RTI A;  3JCU P;  2XB3 A;  3V7B A;  4BQ6 D;  4RTH A;  1V2B A;  3HLZ A;  3LYD A;  4UI2 D;  4BQ8 C;  2VU4 A;  1EQ6 A;  2LNJ A; 
#chains in the Genus database with same CATH topology
 1JHS A;  4RTI A;  4RTH A;  1V2B A;  1EQ6 A;  3JCU P;  3NR5 A;  4LUQ C;  3LYD A;  4N88 B;  3BCY A;  1VR8 A;  4L9H A;  4L9C A;  4ESQ A;  2XB3 A;  3V7B A;  4BQ6 D;  4UI2 D;  4BQ8 C;  2VU4 A;  4N7S B;  1TU1 A;  4M5F B;  4N80 B;  4OUH A;  2VT8 A;  3HLZ A;  3WA5 B;  2LNJ A; 
#chains in the Genus database with same CATH homology
 1TU1 A;  1JHS A;  4RTI A;  3JCU P;  2XB3 A;  3V7B A;  4BQ6 D;  4RTH A;  1V2B A;  3HLZ A;  3LYD A;  4UI2 D;  4BQ8 C;  2VU4 A;  1EQ6 A;  2LNJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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