4UMLA

Crystal structure of ganglioside induced differentiation associated protein 2 (gdap2) macro domain
Total Genus 68
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
221
structure length
201
Chain Sequence
PSQFVDVDTLPSWGDSRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of Gdap2
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2
total genus 68
structure length 201
sequence length 221
ec nomenclature
pdb deposition date 2014-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4umlA00
5CBMA 1ZR3A 5FSYA 2EEEA 3GPGA 4R6TA 4ZY2A 4JLLA 4K3NA 2FG1A 4KSIA 4KYBA 1TY8A 2ACFA 4ZYQA 1LAMA 5FSUA 3EW5A 4J4ZA 1ZR5A 3JZTA 2AFCA 3KQXA 5CMSA 3SIJA 4K0CA 3H8EA 3GQOA 2X47A 4JCAA 1LANA 5CB3A 3IJ3A 3IIDA 4ZX9A 1NJRA 4ZI6A 3SIHA 4GUAA 3H8FA 2BFRA 1BPMA 1HJZA 4JVVA 3Q6ZA 4UMLA 3GPOA 3GQEA 4ABKA 5DUSA 3KR5A 1LAPA 4D86A 4ZY0A 3EJGA 3V2BA 5FSVA 2L8RA 4R76A 3ETIA 3SIGA 3PEIA 5FSXA 4J5RA 2XD7A 3EWPA 3EWQA 3H8GA 5HOLA 3VFQA 2LGRA 5D8NA 5AILA 2FXKA 1GYTA 3EWRA 4GVWA 4IQYA 1BLLE 1TXZA 4R7MA 3KQZA 2DX6A 5CB5A 2FAVA 5FSZA 4ZX8A 3EJFA 4GVVA 3EWOA 4JGKA 4ESSA 3Q71A 2J9AA 3KZWA 1BPNA 3V45A 3SIIA 3T8WA 4X2TA 1LCPA 3KR4A 1YD9A 3JRUA 5HIHA 4ABLA 4J5QA 3IIFA 3GPQA 4TU0A 2VRIA 4J5SA 1VHUA 4ETJA 3EKEA 4ZY1A 2EWBA 4ETKA 1SPVA 2BFQA 5E3BA
chains in the Genus database with same CATH superfamily
5CBMA 1ZR3A 2JZDA 5FSYA 2EEEA 3GPGA 4R6TA 4ZY2A 2JZEA 4JLLA 4K3NA 2FG1A 4KSIA 4KYBA 1TY8A 2ACFA 4ZYQA 1LAMA 5FSUA 3EW5A 4J4ZA 1ZR5A 2KQVA 3JZTA 2AFCA 3KQXA 5CMSA 3SIJA 3H8EA 3GQOA 4K0CA 2X47A 4JCAA 1LANA 5CB3A 3IJ3A 3IIDA 4ZX9A 1NJRA 4ZI6A 3SIHA 4GUAA 3H8FA 2BFRA 1BPMA 1HJZA 4JVVA 3Q6ZA 4UMLA 2RNKA 3GPOA 3GQEA 4ABKA 5DUSA 3KR5A 1LAPA 4D86A 4ZY0A 3EJGA 3V2BA 5FSVA 2L8RA 4R76A 3ETIA 3SIGA 3PEIA 5FSXA 4J5RA 2XD7A 3EWPA 3EWQA 3H8GA 5HOLA 3VFQA 2LGRA 5D8NA 5AILA 2FXKA 1GYTA 3EWRA 4GVWA 4IQYA 1BLLE 1TXZA 4R7MA 2W2GA 3KQZA 2DX6A 5CB5A 2FAVA 5FSZA 4ZX8A 3EJFA 4GVVA 3EWOA 4JGKA 4ESSA 3Q71A 2J9AA 3KZWA 2WCTA 2JZFA 1BPNA 3V45A 3SIIA 3T8WA 4X2TA 1LCPA 3KR4A 1YD9A 3JRUA 5HIHA 4ABLA 4J5QA 3IIFA 3GPQA 4TU0A 2VRIA 4J5SA 1VHUA 4ETJA 3EKEA 4ZY1A 2EWBA 4ETKA 1SPVA 2BFQA 5E3BA
chains in the Genus database with same CATH topology
5CBMA 1ZR3A 5FSYA 2EEEA 3GPGA 4R6TA 4ZY2A 4JLLA 4K3NA 2FG1A 4KSIA 4KYBA 1TY8A 2ACFA 4ZYQA 1LAMA 5FSUA 3EW5A 4J4ZA 1ZR5A 3JZTA 2AFCA 3KQXA 5CMSA 3SIJA 4K0CA 3H8EA 3GQOA 2X47A 4JCAA 1LANA 5CB3A 3IJ3A 3IIDA 4ZX9A 1NJRA 4ZI6A 3SIHA 4GUAA 3H8FA 2BFRA 1BPMA 1HJZA 4JVVA 3Q6ZA 4UMLA 3GPOA 3GQEA 4ABKA 5DUSA 3KR5A 1LAPA 4D86A 4ZY0A 3EJGA 3V2BA 5FSVA 2L8RA 4R76A 3ETIA 3SIGA 3PEIA 5FSXA 4J5RA 2XD7A 3EWPA 3EWQA 3H8GA 5HOLA 3VFQA 2LGRA 5D8NA 5AILA 2FXKA 1GYTA 3EWRA 4GVWA 4IQYA 1BLLE 1TXZA 4R7MA 3KQZA 2DX6A 5CB5A 2FAVA 5FSZA 4ZX8A 3EJFA 4GVVA 3EWOA 4JGKA 4ESSA 3Q71A 2J9AA 3KZWA 1BPNA 3V45A 3SIIA 3T8WA 4X2TA 1LCPA 3KR4A 1YD9A 3JRUA 5HIHA 4ABLA 4J5QA 3IIFA 3GPQA 4TU0A 2VRIA 4J5SA 1VHUA 4ETJA 3EKEA 4ZY1A 2EWBA 4ETKA 1SPVA 2BFQA 5E3BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CBM A;  1ZR3 A;  5FSY A;  2EEE A;  3GPG A;  4R6T A;  4ZY2 A;  4JLL A;  4K3N A;  2FG1 A;  4KSI A;  4KYB A;  1TY8 A;  2ACF A;  4ZYQ A;  1LAM A;  5FSU A;  3EW5 A;  4J4Z A;  1ZR5 A;  3JZT A;  2AFC A;  3KQX A;  5CMS A;  3SIJ A;  4K0C A;  3H8E A;  3GQO A;  2X47 A;  4JCA A;  1LAN A;  5CB3 A;  3IJ3 A;  3IID A;  4ZX9 A;  1NJR A;  4ZI6 A;  3SIH A;  4GUA A;  3H8F A;  2BFR A;  1BPM A;  1HJZ A;  4JVV A;  3Q6Z A;  4UML A;  3GPO A;  3GQE A;  4ABK A;  5DUS A;  3KR5 A;  1LAP A;  4D86 A;  4ZY0 A;  3EJG A;  3V2B A;  5FSV A;  2L8R A;  4R76 A;  3ETI A;  3SIG A;  3PEI A;  5FSX A;  4J5R A;  2XD7 A;  3EWP A;  3EWQ A;  3H8G A;  5HOL A;  3VFQ A;  2LGR A;  5D8N A;  5AIL A;  2FXK A;  1GYT A;  3EWR A;  4GVW A;  4IQY A;  1BLL E;  1TXZ A;  4R7M A;  3KQZ A;  2DX6 A;  5CB5 A;  2FAV A;  5FSZ A;  4ZX8 A;  3EJF A;  4GVV A;  3EWO A;  4JGK A;  4ESS A;  3Q71 A;  2J9A A;  3KZW A;  1BPN A;  3V45 A;  3SII A;  3T8W A;  4X2T A;  1LCP A;  3KR4 A;  1YD9 A;  3JRU A;  5HIH A;  4ABL A;  4J5Q A;  3IIF A;  3GPQ A;  4TU0 A;  2VRI A;  4J5S A;  1VHU A;  4ETJ A;  3EKE A;  4ZY1 A;  2EWB A;  4ETK A;  1SPV A;  2BFQ A;  5E3B A; 
#chains in the Genus database with same CATH topology
 5CBM A;  1ZR3 A;  2JZD A;  5FSY A;  2EEE A;  3GPG A;  4R6T A;  4ZY2 A;  2JZE A;  4JLL A;  4K3N A;  2FG1 A;  4KSI A;  4KYB A;  1TY8 A;  2ACF A;  4ZYQ A;  1LAM A;  5FSU A;  3EW5 A;  4J4Z A;  1ZR5 A;  2KQV A;  3JZT A;  2AFC A;  3KQX A;  5CMS A;  3SIJ A;  3H8E A;  3GQO A;  4K0C A;  2X47 A;  4JCA A;  1LAN A;  5CB3 A;  3IJ3 A;  3IID A;  4ZX9 A;  1NJR A;  4ZI6 A;  3SIH A;  4GUA A;  3H8F A;  2BFR A;  1BPM A;  1HJZ A;  4JVV A;  3Q6Z A;  4UML A;  2RNK A;  3GPO A;  3GQE A;  4ABK A;  5DUS A;  3KR5 A;  1LAP A;  4D86 A;  4ZY0 A;  3EJG A;  3V2B A;  5FSV A;  2L8R A;  4R76 A;  3ETI A;  3SIG A;  3PEI A;  5FSX A;  4J5R A;  2XD7 A;  3EWP A;  3EWQ A;  3H8G A;  5HOL A;  3VFQ A;  2LGR A;  5D8N A;  5AIL A;  2FXK A;  1GYT A;  3EWR A;  4GVW A;  4IQY A;  1BLL E;  1TXZ A;  4R7M A;  2W2G A;  3KQZ A;  2DX6 A;  5CB5 A;  2FAV A;  5FSZ A;  4ZX8 A;  3EJF A;  4GVV A;  3EWO A;  4JGK A;  4ESS A;  3Q71 A;  2J9A A;  3KZW A;  2WCT A;  2JZF A;  1BPN A;  3V45 A;  3SII A;  3T8W A;  4X2T A;  1LCP A;  3KR4 A;  1YD9 A;  3JRU A;  5HIH A;  4ABL A;  4J5Q A;  3IIF A;  3GPQ A;  4TU0 A;  2VRI A;  4J5S A;  1VHU A;  4ETJ A;  3EKE A;  4ZY1 A;  2EWB A;  4ETK A;  1SPV A;  2BFQ A;  5E3B A; 
#chains in the Genus database with same CATH homology
 5CBM A;  1ZR3 A;  5FSY A;  2EEE A;  3GPG A;  4R6T A;  4ZY2 A;  4JLL A;  4K3N A;  2FG1 A;  4KSI A;  4KYB A;  1TY8 A;  2ACF A;  4ZYQ A;  1LAM A;  5FSU A;  3EW5 A;  4J4Z A;  1ZR5 A;  3JZT A;  2AFC A;  3KQX A;  5CMS A;  3SIJ A;  4K0C A;  3H8E A;  3GQO A;  2X47 A;  4JCA A;  1LAN A;  5CB3 A;  3IJ3 A;  3IID A;  4ZX9 A;  1NJR A;  4ZI6 A;  3SIH A;  4GUA A;  3H8F A;  2BFR A;  1BPM A;  1HJZ A;  4JVV A;  3Q6Z A;  4UML A;  3GPO A;  3GQE A;  4ABK A;  5DUS A;  3KR5 A;  1LAP A;  4D86 A;  4ZY0 A;  3EJG A;  3V2B A;  5FSV A;  2L8R A;  4R76 A;  3ETI A;  3SIG A;  3PEI A;  5FSX A;  4J5R A;  2XD7 A;  3EWP A;  3EWQ A;  3H8G A;  5HOL A;  3VFQ A;  2LGR A;  5D8N A;  5AIL A;  2FXK A;  1GYT A;  3EWR A;  4GVW A;  4IQY A;  1BLL E;  1TXZ A;  4R7M A;  3KQZ A;  2DX6 A;  5CB5 A;  2FAV A;  5FSZ A;  4ZX8 A;  3EJF A;  4GVV A;  3EWO A;  4JGK A;  4ESS A;  3Q71 A;  2J9A A;  3KZW A;  1BPN A;  3V45 A;  3SII A;  3T8W A;  4X2T A;  1LCP A;  3KR4 A;  1YD9 A;  3JRU A;  5HIH A;  4ABL A;  4J5Q A;  3IIF A;  3GPQ A;  4TU0 A;  2VRI A;  4J5S A;  1VHU A;  4ETJ A;  3EKE A;  4ZY1 A;  2EWB A;  4ETK A;  1SPV A;  2BFQ A;  5E3B A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...