4UMLA

Crystal structure of ganglioside induced differentiation associated protein 2 (gdap2) macro domain
Total Genus 68
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
68
sequence length
221
structure length
201
Chain Sequence
PSQFVDVDTLPSWGDSRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structure of Gdap2
rcsb
source organism Homo sapiens
molecule tags Signaling protein
molecule keywords GANGLIOSIDE-INDUCED DIFFERENTIATION-ASSOCIATED PROTEIN 2
total genus 68
structure length 201
sequence length 221
ec nomenclature
pdb deposition date 2014-05-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01661 Macro Macro domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.220.10 Alpha Beta 3-Layer(aba) Sandwich Leucine Aminopeptidase, subunit E; domain 1 Leucine Aminopeptidase, subunit E, domain 1 4umlA00
1TY8A 1LAMA 1VHUA 1YD9A 3V2BA 5DUSA 3KQZA 4J5QA 4TU0A 4R76A 3Q71A 3IIDA 4GUAA 4JLLA 3EJGA 3SIHA 5HOLA 5HIHA 3GPGA 2BFQA 4J5RA 5FSZA 4KSIA 3SIJA 3EW5A 3EWOA 4JVVA 3GPOA 4ZY2A 4ABKA 3EKEA 1GYTA 3ETIA 3SIGA 3GQOA 3KR5A 5FSYA 3SIIA 3JRUA 4JGKA 2EEEA 2VRIA 5FSVA 3VFQA 1NJRA 5CBMA 5CMSA 3T8WA 3GQEA 1TXZA 4ABLA 4UMLA 1BPMA 1BLLE 3KQXA 4ZYQA 4GVWA 3EWRA 3H8GA 2L8RA 4R7MA 5CB5A 4X2TA 2BFRA 2XD7A 3H8EA 2FAVA 2FXKA 4KYBA 4ZX9A 2ACFA 4ZY1A 1ZR3A 3JZTA 4K3NA 1LANA 4ETKA 1LAPA 1ZR5A 1HJZA 3EJFA 4ETJA 5CB3A 1BPNA 5FSUA 4ZI6A 2EWBA 2J9AA 3IJ3A 4D86A 3EWPA 3PEIA 4ZY0A 4GVVA 5AILA 3KZWA 2LGRA 3H8FA 4JCAA 3IIFA 5D8NA 5E3BA 1LCPA 4K0CA 4ESSA 4IQYA 2AFCA 2FG1A 3KR4A 5FSXA 3Q6ZA 4R6TA 2X47A 1SPVA 3V45A 4J5SA 3EWQA 4J4ZA 4ZX8A 3GPQA 2DX6A
chains in the Genus database with same CATH superfamily
1TY8A 1LAMA 1VHUA 1YD9A 3V2BA 5DUSA 3KQZA 4J5QA 2JZFA 4TU0A 4R76A 3Q71A 3IIDA 4GUAA 4JLLA 3EJGA 3SIHA 5HOLA 5HIHA 3GPGA 2BFQA 4J5RA 5FSZA 2KQVA 4KSIA 3SIJA 3EW5A 3EWOA 4JVVA 3GPOA 4ZY2A 4ABKA 3EKEA 1GYTA 3ETIA 3SIGA 3GQOA 3KR5A 5FSYA 3SIIA 2W2GA 3JRUA 4JGKA 2EEEA 2VRIA 5FSVA 3VFQA 1NJRA 5CBMA 5CMSA 3T8WA 3GQEA 1TXZA 2RNKA 4UMLA 4ABLA 1BPMA 1BLLE 3KQXA 4ZYQA 4GVWA 3EWRA 3H8GA 2L8RA 4R7MA 5CB5A 4X2TA 2BFRA 2XD7A 3H8EA 2FAVA 2FXKA 4KYBA 4ZX9A 2ACFA 4ZY1A 1ZR3A 3JZTA 4K3NA 1LANA 4ETKA 1LAPA 1ZR5A 1HJZA 3EJFA 2WCTA 4ETJA 5CB3A 1BPNA 5FSUA 4ZI6A 2EWBA 2J9AA 2JZDA 3IJ3A 4D86A 3EWPA 3PEIA 4ZY0A 4GVVA 5AILA 3KZWA 2LGRA 2JZEA 3H8FA 4JCAA 3IIFA 5D8NA 5E3BA 1LCPA 4K0CA 4ESSA 4IQYA 2AFCA 2FG1A 3KR4A 5FSXA 3Q6ZA 4R6TA 2X47A 1SPVA 3V45A 4J5SA 3EWQA 4J4ZA 4ZX8A 3GPQA 2DX6A
chains in the Genus database with same CATH topology
1TY8A 1LAMA 1VHUA 1YD9A 3V2BA 5DUSA 3KQZA 4J5QA 4TU0A 4R76A 3Q71A 3IIDA 4GUAA 4JLLA 3EJGA 3SIHA 5HOLA 5HIHA 3GPGA 2BFQA 4J5RA 5FSZA 4KSIA 3SIJA 3EW5A 3EWOA 4JVVA 3GPOA 4ZY2A 4ABKA 3EKEA 1GYTA 3ETIA 3SIGA 3GQOA 3KR5A 5FSYA 3SIIA 3JRUA 4JGKA 2EEEA 2VRIA 5FSVA 3VFQA 1NJRA 5CBMA 5CMSA 3T8WA 3GQEA 1TXZA 4ABLA 4UMLA 1BPMA 1BLLE 3KQXA 4ZYQA 4GVWA 3EWRA 3H8GA 2L8RA 4R7MA 5CB5A 4X2TA 2BFRA 2XD7A 3H8EA 2FAVA 2FXKA 4KYBA 4ZX9A 2ACFA 4ZY1A 1ZR3A 3JZTA 4K3NA 1LANA 4ETKA 1LAPA 1ZR5A 1HJZA 3EJFA 4ETJA 5CB3A 1BPNA 5FSUA 4ZI6A 2EWBA 2J9AA 3IJ3A 4D86A 3EWPA 3PEIA 4ZY0A 4GVVA 5AILA 3KZWA 2LGRA 3H8FA 4JCAA 3IIFA 5D8NA 5E3BA 1LCPA 4K0CA 4ESSA 4IQYA 2AFCA 2FG1A 3KR4A 5FSXA 3Q6ZA 4R6TA 2X47A 1SPVA 3V45A 4J5SA 3EWQA 4J4ZA 4ZX8A 3GPQA 2DX6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1TY8 A;  1LAM A;  1VHU A;  1YD9 A;  3V2B A;  5DUS A;  3KQZ A;  4J5Q A;  4TU0 A;  4R76 A;  3Q71 A;  3IID A;  4GUA A;  4JLL A;  3EJG A;  3SIH A;  5HOL A;  5HIH A;  3GPG A;  2BFQ A;  4J5R A;  5FSZ A;  4KSI A;  3SIJ A;  3EW5 A;  3EWO A;  4JVV A;  3GPO A;  4ZY2 A;  4ABK A;  3EKE A;  1GYT A;  3ETI A;  3SIG A;  3GQO A;  3KR5 A;  5FSY A;  3SII A;  3JRU A;  4JGK A;  2EEE A;  2VRI A;  5FSV A;  3VFQ A;  1NJR A;  5CBM A;  5CMS A;  3T8W A;  3GQE A;  1TXZ A;  4ABL A;  4UML A;  1BPM A;  1BLL E;  3KQX A;  4ZYQ A;  4GVW A;  3EWR A;  3H8G A;  2L8R A;  4R7M A;  5CB5 A;  4X2T A;  2BFR A;  2XD7 A;  3H8E A;  2FAV A;  2FXK A;  4KYB A;  4ZX9 A;  2ACF A;  4ZY1 A;  1ZR3 A;  3JZT A;  4K3N A;  1LAN A;  4ETK A;  1LAP A;  1ZR5 A;  1HJZ A;  3EJF A;  4ETJ A;  5CB3 A;  1BPN A;  5FSU A;  4ZI6 A;  2EWB A;  2J9A A;  3IJ3 A;  4D86 A;  3EWP A;  3PEI A;  4ZY0 A;  4GVV A;  5AIL A;  3KZW A;  2LGR A;  3H8F A;  4JCA A;  3IIF A;  5D8N A;  5E3B A;  1LCP A;  4K0C A;  4ESS A;  4IQY A;  2AFC A;  2FG1 A;  3KR4 A;  5FSX A;  3Q6Z A;  4R6T A;  2X47 A;  1SPV A;  3V45 A;  4J5S A;  3EWQ A;  4J4Z A;  4ZX8 A;  3GPQ A;  2DX6 A; 
#chains in the Genus database with same CATH topology
 1TY8 A;  1LAM A;  1VHU A;  1YD9 A;  3V2B A;  5DUS A;  3KQZ A;  4J5Q A;  2JZF A;  4TU0 A;  4R76 A;  3Q71 A;  3IID A;  4GUA A;  4JLL A;  3EJG A;  3SIH A;  5HOL A;  5HIH A;  3GPG A;  2BFQ A;  4J5R A;  5FSZ A;  2KQV A;  4KSI A;  3SIJ A;  3EW5 A;  3EWO A;  4JVV A;  3GPO A;  4ZY2 A;  4ABK A;  3EKE A;  1GYT A;  3ETI A;  3SIG A;  3GQO A;  3KR5 A;  5FSY A;  3SII A;  2W2G A;  3JRU A;  4JGK A;  2EEE A;  2VRI A;  5FSV A;  3VFQ A;  1NJR A;  5CBM A;  5CMS A;  3T8W A;  3GQE A;  1TXZ A;  2RNK A;  4UML A;  4ABL A;  1BPM A;  1BLL E;  3KQX A;  4ZYQ A;  4GVW A;  3EWR A;  3H8G A;  2L8R A;  4R7M A;  5CB5 A;  4X2T A;  2BFR A;  2XD7 A;  3H8E A;  2FAV A;  2FXK A;  4KYB A;  4ZX9 A;  2ACF A;  4ZY1 A;  1ZR3 A;  3JZT A;  4K3N A;  1LAN A;  4ETK A;  1LAP A;  1ZR5 A;  1HJZ A;  3EJF A;  2WCT A;  4ETJ A;  5CB3 A;  1BPN A;  5FSU A;  4ZI6 A;  2EWB A;  2J9A A;  2JZD A;  3IJ3 A;  4D86 A;  3EWP A;  3PEI A;  4ZY0 A;  4GVV A;  5AIL A;  3KZW A;  2LGR A;  2JZE A;  3H8F A;  4JCA A;  3IIF A;  5D8N A;  5E3B A;  1LCP A;  4K0C A;  4ESS A;  4IQY A;  2AFC A;  2FG1 A;  3KR4 A;  5FSX A;  3Q6Z A;  4R6T A;  2X47 A;  1SPV A;  3V45 A;  4J5S A;  3EWQ A;  4J4Z A;  4ZX8 A;  3GPQ A;  2DX6 A; 
#chains in the Genus database with same CATH homology
 1TY8 A;  1LAM A;  1VHU A;  1YD9 A;  3V2B A;  5DUS A;  3KQZ A;  4J5Q A;  4TU0 A;  4R76 A;  3Q71 A;  3IID A;  4GUA A;  4JLL A;  3EJG A;  3SIH A;  5HOL A;  5HIH A;  3GPG A;  2BFQ A;  4J5R A;  5FSZ A;  4KSI A;  3SIJ A;  3EW5 A;  3EWO A;  4JVV A;  3GPO A;  4ZY2 A;  4ABK A;  3EKE A;  1GYT A;  3ETI A;  3SIG A;  3GQO A;  3KR5 A;  5FSY A;  3SII A;  3JRU A;  4JGK A;  2EEE A;  2VRI A;  5FSV A;  3VFQ A;  1NJR A;  5CBM A;  5CMS A;  3T8W A;  3GQE A;  1TXZ A;  4ABL A;  4UML A;  1BPM A;  1BLL E;  3KQX A;  4ZYQ A;  4GVW A;  3EWR A;  3H8G A;  2L8R A;  4R7M A;  5CB5 A;  4X2T A;  2BFR A;  2XD7 A;  3H8E A;  2FAV A;  2FXK A;  4KYB A;  4ZX9 A;  2ACF A;  4ZY1 A;  1ZR3 A;  3JZT A;  4K3N A;  1LAN A;  4ETK A;  1LAP A;  1ZR5 A;  1HJZ A;  3EJF A;  4ETJ A;  5CB3 A;  1BPN A;  5FSU A;  4ZI6 A;  2EWB A;  2J9A A;  3IJ3 A;  4D86 A;  3EWP A;  3PEI A;  4ZY0 A;  4GVV A;  5AIL A;  3KZW A;  2LGR A;  3H8F A;  4JCA A;  3IIF A;  5D8N A;  5E3B A;  1LCP A;  4K0C A;  4ESS A;  4IQY A;  2AFC A;  2FG1 A;  3KR4 A;  5FSX A;  3Q6Z A;  4R6T A;  2X47 A;  1SPV A;  3V45 A;  4J5S A;  3EWQ A;  4J4Z A;  4ZX8 A;  3GPQ A;  2DX6 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...