4UQIA

Ap2 controls clathrin polymerization with a membrane-activated switch
Total Genus 233
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
233
sequence length
600
structure length
600
Chain Sequence
GMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVCKLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDLASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSPDLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPPEDPAVRGRLTECLETILNKAQEPPKSKKVQHSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEFSHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIREEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALLLSTYIKFVNLFPEVKATIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEEMPPFPER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch.
pubmed doi rcsb
molecule tags Endocytosis
source organism Rattus norvegicus
molecule keywords AP-2 COMPLEX SUBUNIT ALPHA-2
total genus 233
structure length 600
sequence length 600
ec nomenclature
pdb deposition date 2014-06-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01602 Adaptin_N Adaptin N terminal region
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.25.10.10 Mainly Alpha Alpha Horseshoe Leucine-rich Repeat Variant Leucine-rich Repeat Variant 4uqiA00
4FZDA 1EE5A 4I5LA 4L7MA 1UPKA 4PVZA 4U5UA 1M8XA 3NMWA 3LWWA 2GL7A 2Z5MA 4YI0C 4ADYA 3UKXB 3Q0LA 4UAEA 5D5KC 3Q0QA 4IMJA 2F31A 2IWHA 1PJMB 3UKWB 3C5WA 4U5VA 4FZAA 4R10A 4IMIA 3LTMA 1QGKA 3AU3A 5AEIA 2FV2A 1O6PA 4DZSA 5SVZA 3WYFC 4B8OA 4FZFA 3OUXA 5HHGE 4RXHB 5EWPA 5KL1A 1WA5B 4EVAA 1M8WA 4BA3A 2XA7B 3V6YA 1UPLA 1W63A 3IBVA 2QK1A 4R0ZA 4JW2B 2X19B 3K7VA 2IX3A 4U5OA 3H3DX 2JKRA 5HUWC 2DB0A 1O6OA 3K5QA 3FEXC 3GNIA 5J3VA 2QNAA 2Z5OA 3VE6A 5KLRB 4P6ZG 3RZXA 3OQSA 4LACA 3K61A 1LRVA 3FGAA 5KL8A 4UWXA 4HTVA 4K6JA 3GRLA 1I7WA 5EKGA 4GMOA 3UKZB 5K9SA 2Z5JA 4B8JA 3C2GA 2BNXA 3EA5B 2PF4A 3ND2A 1QGRA 4U54A 4CV5B 1EJLI 4FFBC 3A6PA 3OPBA 3Q0NA 1T08A 4ZDUA 4CT6B 3OBVA 3Q0MA 4NEEA 1Q1SC 5CTTA 5E6QB 4V3RA 4B18A 2W3CA 4MZ6E 3UL0B 1I7XA 4V3OA 3TJZB 4A0CA 3V71A 3K7WA 3GAEA 3V74A 5JJAA 1M8ZA 3LTJA 5H2WA 3QGBA 4CB8A 2IE4A 5LSWA 3K62A 2IE3A 4KZGA 3Q0SA 3QMLC 3TT9A 3ZIPA 4MFUA 4U3JC 1BK5A 3QHEA 1XQRA 1Y2AC 4DJSA 5HUYC 5SW9A 4DB9A 4UADA 3ZIOA 2QK2A 2BCTA 2VGLA 5H2XA 4UAFB 2IAEB 3ZIRA 4EVPA 4YGXA 2NYMB 1WA5C 5BYMA 4OIHA 1G3JA 3TPMA 3WPTA 3GQ2A 3L6YA 3ZKVA 1IQ1C 1IB2A 1F59A 4QMHA 3BX3A 4D49A 4CRUB 4RV1A 1V18A 4R11A 4H3KA 2RU4B 5B56A 4BPLA 1LUJA 4FQ3A 4TNMA 5BZ1A 2JKTA 3FEYC 1EE4A 3K64A 2OF3A 1BK6A 4HNMA 3GVOA 3O2SA 1U6GC 2XA7A 4E4VA 1OYZA 4CRVB 5BZUA 2Z6HA 4XZRB 3DADA 3QG9A 1HO8A 4NZWA 2NYLA 4I2WA 4U5SA 3BSXA 3K4EA 2Z5KA 4P6ZB 1EJYI 4PLQA 3EBBA 4QMJA 3O2QA 2NPPA 3O4XA 2QMRA 1M1EA 3Q0OA 3NOWA 1Z2CB 1JDHA 1QBKB 4CT7B 4HM9A 3ODRA 4YK6A 2JDQA 2YNSA 2WTKA 3C2HA 3GB8A 3WOZA 4PLRA 2YJYA 4MFVA 3PSTA 3BCTA 2PKGA 3K5YA 4FDDA 3K5ZA 4EV8A 2VGLB 3KNDA 2C1TA 4O27A 4I2ZA 3TJ3A 3TPOA 4QMIA 4U58A 5EKFA 1JPPA 1W63B 2Z6GA 4CB9A 1GCJA 1QZ7A 3WOYA 4UQIA 4B8PA 1M8YA 4V3QA 4YJEA 2JKRB 3Q0PA 2BKUB 3Q5UA 4G3AA 4D4EA 3IFQA 3T7UA 5DN7A 5BZ5A 3QGCA 4PLSA 5K6SA 3L3QA 2JKTB 1W9CA 3FGAB 3UKYB 3GVTA 4MZ5E 3NMXA 4EVTA 4OO6A 3BX2A 2YNRA 3PSPA 3ZIQA 3VWAA 4GMNA 3GS3A 1PJNB 4EV9A 4JLQA 4U5LA 4Y5JA 2IW3A 1JPWA 3TX7A 2NYLB 3ZINA 2OT8A 4RZPA 5SWFA 3Q0RA 4H3HA 3NMZA 5KLTB 3L6XA 2C1MA 2IAEA 2Q5DA 3DW8A 1IALA 2NPPB 3O2TA 3BTRC 4WV6A 1XQSA 5BZVA 2NYMA 3K49A 2JAKA 1IBRB 2BAPA 1M5NS 3RZ9A 3EG5B 3L3FX 1B3UA 1Q1TC 2H4MA 4DB6A 5FC8E 1TH1A 4U5NA 4K92A 3ZHPA 3OUWA 2RU4A 3BWTA 2Z5NA 4DB8A 2P8QA 3BSBA 4I5NA 3UL1B 4UQIB 1UKLA 1XM9A 3W3UA 4CBAA 2X1GF 3UVUA 1UN0A 5KLAA 4DVGB 4HXTA 4DBAA 3ODSA 4YJLA 4BQKA
chains in the Genus database with same CATH superfamily
4FZDA 1EE5A 4I5LA 4L7MA 1UPKA 4PVZA 4U5UA 1M8XA 3NMWA 3LWWA 2GL7A 2Z5MA 4YI0C 4ADYA 3UKXB 3Q0LA 4UAEA 5D5KC 3Q0QA 4IMJA 2F31A 2IWHA 1PJMB 3UKWB 3C5WA 4U5VA 4FZAA 4R10A 4IMIA 3LTMA 1QGKA 3AU3A 5AEIA 2FV2A 1O6PA 4DZSA 5SVZA 1N4KA 3WYFC 4B8OA 3SL9A 3UJ0A 4FZFA 5CLDA 3OUXA 5HHGE 4RXHB 5EWPA 5KL1A 1WA5B 4EVAA 1M8WA 4BA3A 2XA7B 3V6YA 1UPLA 1W63A 3IBVA 2QK1A 4R0ZA 4JW2B 2X19B 3K7VA 2IX3A 4U5OA 3H3DX 2JKRA 5HUWC 2DB0A 1O6OA 3K5QA 3T8SA 3FEXC 3GNIA 5J3VA 2QNAA 2Z5OA 3VE6A 5KLRB 4P6ZG 3RZXA 3OQSA 4LACA 3K61A 1LRVA 3FGAA 5KL8A 4UWXA 4HTVA 4K6JA 3GRLA 3JX7A 1I7WA 5EKGA 4GMOA 3UKZB 5K9SA 2Z5JA 4B8JA 3C2GA 2BNXA 4JW3C 3VLEA 3EA5B 2PF4A 3ND2A 1QGRA 4U54A 4CV5B 1EJLI 4FFBC 3A6PA 3OPBA 3Q0NA 1T08A 4ZDUA 5KUBA 4CT6B 3OBVA 3Q0MA 4NEEA 1Q1SC 5CL5A 5CTTA 5E6QB 4V3RA 4B18A 2W3CA 4MZ6E 3UL0B 1I7XA 4V3OA 3TJZB 4A0CA 3V71A 3K7WA 3GAEA 3V74A 5JJAA 1M8ZA 3LTJA 5H2WA 3QGBA 4CB8A 2IE4A 5LSWA 3K62A 2IE3A 4KZGA 3Q0SA 3QMLC 3TT9A 3ZIPA 3SLAA 3UJ4A 4MFUA 4U3JC 1BK5A 3QHEA 1XQRA 1Y2AC 4I96A 4DJSA 5CL8A 4L4IA 5HUYC 5SW9A 4DB9A 4UADA 3ZIOA 2QK2A 2BCTA 2VGLA 5H2XA 4UAFB 2IAEB 3ZIRA 4EVPA 3ZILA 5CL4A 4YGXA 2NYMB 1WA5C 5BYMA 4OIHA 1G3JA 3TPMA 4JKQA 3WPTA 3GQ2A 3L6YA 3JY1A 3ZKVA 1IQ1C 1IB2A 1F59A 4QMHA 3BX3A 4D49A 4CRUB 4RV1A 1V18A 4R11A 4H3KA 2RU4B 5B56A 5CLAA 4BPLA 1LUJA 4FQ3A 4I3NA 4TNMA 5BZ1A 2JKTA 3FEYC 1EE4A 3K64A 2OF3A 1BK6A 4HNMA 4U2XD 3GVOA 3O2SA 1U6GC 2XA7A 4E4VA 1OYZA 4CRVB 5BZUA 2Z6HA 4FP7A 4XZRB 3JXZA 3DADA 3QG9A 1HO8A 4NZWA 2NYLA 5CLCA 4I8MA 4I2WA 1TE4A 4U5SA 3ZIKA 3BSXA 5CLBA 3K4EA 4I0YA 2Z5KA 4P6ZB 1EJYI 4PLQA 3EBBA 4A3TA 4QMJA 3O2QA 2NPPA 3O4XA 2QMRA 1M1EA 3Q0OA 3NOWA 4L4HA 1Z2CB 1JDHA 1QBKB 4CT7B 4HM9A 3ODRA 2XOAA 4YK6A 2JDQA 2YNSA 2WTKA 3C2HA 3GB8A 3WOZA 4PLRA 2YJYA 4MFVA 3PSTA 3BCTA 2PKGA 3K5YA 4A3VA 4FDDA 3K5ZA 4EV8A 2VGLB 4I37A 3KNDA 2C1TA 4O27A 4I2ZA 3TJ3A 3TPOA 4QMIA 5CL9A 4U58A 5EKFA 1JPPA 1W63B 2Z6GA 4CB9A 4I2SA 1GCJA 1QZ7A 3WOYA 4UQIA 4B8PA 1M8YA 3VLFA 4V3QA 4YJEA 5CL6A 2JKRB 5CLEA 3Q0PA 2BKUB 3Q5UA 4G3AA 4D4EA 3IFQA 3T7UA 3JXYA 5DN7A 5BZ5A 3QGCA 4PLSA 5K6SA 3L3QA 2JKTB 1W9CA 3FGAB 4I1EA 3UKYB 3GVTA 4MZ5E 3NMXA 4EVTA 4OO6A 3BX2A 2YNRA 3PSPA 3ZIQA 3VWAA 4GMNA 3GS3A 1PJNB 4EV9A 4JLQA 4U5LA 4Y5JA 2IW3A 1JPWA 3TX7A 2NYLB 3ZINA 2OT8A 4RZPA 5SWFA 3Q0RA 4H3HA 3NMZA 5KLTB 3L6XA 2C1MA 2IAEA 2Q5DA 1LSHA 3DW8A 1IALA 2NPPB 3O2TA 3BTRC 4WV6A 1XQSA 5BZVA 2NYMA 3K49A 4JW2A 2JAKA 1IBRB 2BAPA 1M5NS 3RZ9A 4I6IA 3EG5B 3L3FX 1B3UA 1Q1TC 2H4MA 4DB6A 5FC8E 1TH1A 4U5NA 4K92A 3ZHPA 3OUWA 2RU4A 3BWTA 2Z5NA 4DB8A 2P8QA 3BSBA 5CL3A 4I5NA 3UL1B 5CL7A 3BVSA 4UQIB 1UKLA 1XM9A 3W3UA 4CBAA 2X1GF 3UVUA 1UN0A 5KLAA 4I7IA 4HXTA 4DVGB 3VLDA 3ODSA 4DBAA 4YJLA 4BQKA
chains in the Genus database with same CATH topology
4FZDA 1EE5A 4I5LA 4L7MA 1UPKA 4PVZA 4U5UA 1M8XA 3NMWA 3LWWA 2GL7A 2Z5MA 4YI0C 4ADYA 3UKXB 3Q0LA 4UAEA 5D5KC 3Q0QA 4IMJA 2F31A 2IWHA 1PJMB 3UKWB 3C5WA 4U5VA 4FZAA 4R10A 4IMIA 3LTMA 1QGKA 3AU3A 5AEIA 2FV2A 1O6PA 4DZSA 5SVZA 3WYFC 4B8OA 3SL9A 4FZFA 5CLDA 3OUXA 5HHGE 4RXHB 5EWPA 5KL1A 1WA5B 4EVAA 1M8WA 4BA3A 2XA7B 3V6YA 1UPLA 1W63A 3IBVA 2QK1A 4R0ZA 4JW2B 2X19B 3K7VA 2IX3A 4U5OA 3H3DX 2JKRA 5HUWC 2DB0A 1O6OA 3K5QA 3FEXC 3GNIA 5J3VA 2QNAA 2Z5OA 3VE6A 5KLRB 4P6ZG 3RZXA 3OQSA 4LACA 3K61A 1LRVA 3FGAA 5KL8A 4UWXA 4HTVA 4K6JA 3GRLA 3JX7A 1I7WA 5EKGA 4GMOA 3UKZB 5K9SA 2Z5JA 4B8JA 3C2GA 2BNXA 4JW3C 3VLEA 3EA5B 2PF4A 3ND2A 1QGRA 4U54A 4CV5B 1EJLI 4FFBC 3A6PA 3OPBA 3Q0NA 1T08A 4ZDUA 5KUBA 4CT6B 3OBVA 3Q0MA 4NEEA 1Q1SC 5CL5A 5CTTA 5E6QB 4V3RA 4B18A 2W3CA 4MZ6E 3UL0B 1I7XA 4V3OA 3TJZB 4A0CA 3V71A 3K7WA 3GAEA 3V74A 5JJAA 1M8ZA 3LTJA 5H2WA 3QGBA 4CB8A 2IE4A 5LSWA 3K62A 2IE3A 4KZGA 3Q0SA 3QMLC 3TT9A 3ZIPA 3SLAA 4MFUA 4U3JC 1BK5A 3QHEA 1XQRA 1Y2AC 4I96A 4DJSA 5CL8A 4L4IA 5HUYC 5SW9A 4DB9A 4UADA 3ZIOA 2QK2A 2BCTA 2VGLA 5H2XA 4UAFB 2IAEB 3ZIRA 4EVPA 3ZILA 5CL4A 4YGXA 2NYMB 1WA5C 5BYMA 4OIHA 1G3JA 3TPMA 4JKQA 3WPTA 3GQ2A 3L6YA 3JY1A 3ZKVA 1IQ1C 1IB2A 1F59A 4QMHA 3BX3A 4D49A 4CRUB 4RV1A 1V18A 4R11A 4H3KA 2RU4B 5B56A 5CLAA 4BPLA 1LUJA 4FQ3A 4I3NA 4TNMA 5BZ1A 2JKTA 3FEYC 1EE4A 3K64A 2OF3A 1BK6A 4HNMA 4U2XD 3GVOA 3O2SA 1U6GC 2XA7A 4E4VA 1OYZA 4CRVB 5BZUA 2Z6HA 4FP7A 4XZRB 3JXZA 3DADA 3QG9A 1HO8A 4NZWA 2NYLA 5CLCA 4I8MA 4I2WA 1TE4A 4U5SA 3ZIKA 3BSXA 5CLBA 3K4EA 4I0YA 2Z5KA 4P6ZB 1EJYI 4PLQA 3EBBA 4A3TA 4QMJA 3O2QA 2NPPA 3O4XA 2QMRA 1M1EA 3Q0OA 3NOWA 4L4HA 1Z2CB 1JDHA 1QBKB 4CT7B 4HM9A 3ODRA 2XOAA 4YK6A 2JDQA 2YNSA 2WTKA 3C2HA 3GB8A 3WOZA 4PLRA 2YJYA 4MFVA 3PSTA 3BCTA 2PKGA 3K5YA 4A3VA 4FDDA 3K5ZA 4EV8A 2VGLB 4I37A 3KNDA 2C1TA 4O27A 4I2ZA 3TJ3A 3TPOA 4QMIA 5CL9A 4U58A 5EKFA 1JPPA 1W63B 2Z6GA 4CB9A 4I2SA 1GCJA 1QZ7A 3WOYA 4UQIA 4B8PA 1M8YA 3VLFA 4V3QA 4YJEA 5CL6A 2JKRB 5CLEA 3Q0PA 2BKUB 3Q5UA 4G3AA 4D4EA 3IFQA 3T7UA 3JXYA 5DN7A 5BZ5A 3QGCA 4PLSA 5K6SA 3L3QA 2JKTB 1W9CA 3FGAB 4I1EA 3UKYB 3GVTA 4MZ5E 3NMXA 4EVTA 4OO6A 3BX2A 2YNRA 3PSPA 3ZIQA 3VWAA 4GMNA 3GS3A 1PJNB 4EV9A 4JLQA 4U5LA 4Y5JA 2IW3A 1JPWA 3TX7A 2NYLB 3ZINA 2OT8A 4RZPA 5SWFA 3Q0RA 4H3HA 3NMZA 5KLTB 3L6XA 2C1MA 2IAEA 2Q5DA 3DW8A 1IALA 2NPPB 3O2TA 3BTRC 4WV6A 1XQSA 5BZVA 2NYMA 3K49A 4JW2A 2JAKA 1IBRB 2BAPA 1M5NS 3RZ9A 4I6IA 3EG5B 3L3FX 1B3UA 1Q1TC 2H4MA 4DB6A 5FC8E 1TH1A 4U5NA 4K92A 3ZHPA 3OUWA 2RU4A 3BWTA 2Z5NA 4DB8A 2P8QA 3BSBA 5CL3A 4I5NA 3UL1B 5CL7A 3BVSA 4UQIB 1UKLA 1XM9A 3W3UA 4CBAA 2X1GF 3UVUA 1UN0A 5KLAA 4I7IA 4HXTA 4DVGB 3VLDA 3ODSA 4DBAA 4YJLA 4BQKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FZD A;  1EE5 A;  4I5L A;  4L7M A;  1UPK A;  4PVZ A;  4U5U A;  1M8X A;  3NMW A;  3LWW A;  2GL7 A;  2Z5M A;  4YI0 C;  4ADY A;  3UKX B;  3Q0L A;  4UAE A;  5D5K C;  3Q0Q A;  4IMJ A;  2F31 A;  2IWH A;  1PJM B;  3UKW B;  3C5W A;  4U5V A;  4FZA A;  4R10 A;  4IMI A;  3LTM A;  1QGK A;  3AU3 A;  5AEI A;  2FV2 A;  1O6P A;  4DZS A;  5SVZ A;  3WYF C;  4B8O A;  4FZF A;  3OUX A;  5HHG E;  4RXH B;  5EWP A;  5KL1 A;  1WA5 B;  4EVA A;  1M8W A;  4BA3 A;  2XA7 B;  3V6Y A;  1UPL A;  1W63 A;  3IBV A;  2QK1 A;  4R0Z A;  4JW2 B;  2X19 B;  3K7V A;  2IX3 A;  4U5O A;  3H3D X;  2JKR A;  5HUW C;  2DB0 A;  1O6O A;  3K5Q A;  3FEX C;  3GNI A;  5J3V A;  2QNA A;  2Z5O A;  3VE6 A;  5KLR B;  4P6Z G;  3RZX A;  3OQS A;  4LAC A;  3K61 A;  1LRV A;  3FGA A;  5KL8 A;  4UWX A;  4HTV A;  4K6J A;  3GRL A;  1I7W A;  5EKG A;  4GMO A;  3UKZ B;  5K9S A;  2Z5J A;  4B8J A;  3C2G A;  2BNX A;  3EA5 B;  2PF4 A;  3ND2 A;  1QGR A;  4U54 A;  4CV5 B;  1EJL I;  4FFB C;  3A6P A;  3OPB A;  3Q0N A;  1T08 A;  4ZDU A;  4CT6 B;  3OBV A;  3Q0M A;  4NEE A;  1Q1S C;  5CTT A;  5E6Q B;  4V3R A;  4B18 A;  2W3C A;  4MZ6 E;  3UL0 B;  1I7X A;  4V3O A;  3TJZ B;  4A0C A;  3V71 A;  3K7W A;  3GAE A;  3V74 A;  5JJA A;  1M8Z A;  3LTJ A;  5H2W A;  3QGB A;  4CB8 A;  2IE4 A;  5LSW A;  3K62 A;  2IE3 A;  4KZG A;  3Q0S A;  3QML C;  3TT9 A;  3ZIP A;  4MFU A;  4U3J C;  1BK5 A;  3QHE A;  1XQR A;  1Y2A C;  4DJS A;  5HUY C;  5SW9 A;  4DB9 A;  4UAD A;  3ZIO A;  2QK2 A;  2BCT A;  2VGL A;  5H2X A;  4UAF B;  2IAE B;  3ZIR A;  4EVP A;  4YGX A;  2NYM B;  1WA5 C;  5BYM A;  4OIH A;  1G3J A;  3TPM A;  3WPT A;  3GQ2 A;  3L6Y A;  3ZKV A;  1IQ1 C;  1IB2 A;  1F59 A;  4QMH A;  3BX3 A;  4D49 A;  4CRU B;  4RV1 A;  1V18 A;  4R11 A;  4H3K A;  2RU4 B;  5B56 A;  4BPL A;  1LUJ A;  4FQ3 A;  4TNM A;  5BZ1 A;  2JKT A;  3FEY C;  1EE4 A;  3K64 A;  2OF3 A;  1BK6 A;  4HNM A;  3GVO A;  3O2S A;  1U6G C;  2XA7 A;  4E4V A;  1OYZ A;  4CRV B;  5BZU A;  2Z6H A;  4XZR B;  3DAD A;  3QG9 A;  1HO8 A;  4NZW A;  2NYL A;  4I2W A;  4U5S A;  3BSX A;  3K4E A;  2Z5K A;  4P6Z B;  1EJY I;  4PLQ A;  3EBB A;  4QMJ A;  3O2Q A;  2NPP A;  3O4X A;  2QMR A;  1M1E A;  3Q0O A;  3NOW A;  1Z2C B;  1JDH A;  1QBK B;  4CT7 B;  4HM9 A;  3ODR A;  4YK6 A;  2JDQ A;  2YNS A;  2WTK A;  3C2H A;  3GB8 A;  3WOZ A;  4PLR A;  2YJY A;  4MFV A;  3PST A;  3BCT A;  2PKG A;  3K5Y A;  4FDD A;  3K5Z A;  4EV8 A;  2VGL B;  3KND A;  2C1T A;  4O27 A;  4I2Z A;  3TJ3 A;  3TPO A;  4QMI A;  4U58 A;  5EKF A;  1JPP A;  1W63 B;  2Z6G A;  4CB9 A;  1GCJ A;  1QZ7 A;  3WOY A;  4UQI A;  4B8P A;  1M8Y A;  4V3Q A;  4YJE A;  2JKR B;  3Q0P A;  2BKU B;  3Q5U A;  4G3A A;  4D4E A;  3IFQ A;  3T7U A;  5DN7 A;  5BZ5 A;  3QGC A;  4PLS A;  5K6S A;  3L3Q A;  2JKT B;  1W9C A;  3FGA B;  3UKY B;  3GVT A;  4MZ5 E;  3NMX A;  4EVT A;  4OO6 A;  3BX2 A;  2YNR A;  3PSP A;  3ZIQ A;  3VWA A;  4GMN A;  3GS3 A;  1PJN B;  4EV9 A;  4JLQ A;  4U5L A;  4Y5J A;  2IW3 A;  1JPW A;  3TX7 A;  2NYL B;  3ZIN A;  2OT8 A;  4RZP A;  5SWF A;  3Q0R A;  4H3H A;  3NMZ A;  5KLT B;  3L6X A;  2C1M A;  2IAE A;  2Q5D A;  3DW8 A;  1IAL A;  2NPP B;  3O2T A;  3BTR C;  4WV6 A;  1XQS A;  5BZV A;  2NYM A;  3K49 A;  2JAK A;  1IBR B;  2BAP A;  1M5N S;  3RZ9 A;  3EG5 B;  3L3F X;  1B3U A;  1Q1T C;  2H4M A;  4DB6 A;  5FC8 E;  1TH1 A;  4U5N A;  4K92 A;  3ZHP A;  3OUW A;  2RU4 A;  3BWT A;  2Z5N A;  4DB8 A;  2P8Q A;  3BSB A;  4I5N A;  3UL1 B;  4UQI B;  1UKL A;  1XM9 A;  3W3U A;  4CBA A;  2X1G F;  3UVU A;  1UN0 A;  5KLA A;  4DVG B;  4HXT A;  4DBA A;  3ODS A;  4YJL A;  4BQK A; 
#chains in the Genus database with same CATH topology
 4FZD A;  1EE5 A;  4I5L A;  4L7M A;  1UPK A;  4PVZ A;  4U5U A;  1M8X A;  3NMW A;  3LWW A;  2GL7 A;  2Z5M A;  4YI0 C;  4ADY A;  3UKX B;  3Q0L A;  4UAE A;  5D5K C;  3Q0Q A;  4IMJ A;  2F31 A;  2IWH A;  1PJM B;  3UKW B;  3C5W A;  4U5V A;  4FZA A;  4R10 A;  4IMI A;  3LTM A;  1QGK A;  3AU3 A;  5AEI A;  2FV2 A;  1O6P A;  4DZS A;  5SVZ A;  1N4K A;  3WYF C;  4B8O A;  3SL9 A;  3UJ0 A;  4FZF A;  5CLD A;  3OUX A;  5HHG E;  4RXH B;  5EWP A;  5KL1 A;  1WA5 B;  4EVA A;  1M8W A;  4BA3 A;  2XA7 B;  3V6Y A;  1UPL A;  1W63 A;  3IBV A;  2QK1 A;  4R0Z A;  4JW2 B;  2X19 B;  3K7V A;  2IX3 A;  4U5O A;  3H3D X;  2JKR A;  5HUW C;  2DB0 A;  1O6O A;  3K5Q A;  3T8S A;  3FEX C;  3GNI A;  5J3V A;  2QNA A;  2Z5O A;  3VE6 A;  5KLR B;  4P6Z G;  3RZX A;  3OQS A;  4LAC A;  3K61 A;  1LRV A;  3FGA A;  5KL8 A;  4UWX A;  4HTV A;  4K6J A;  3GRL A;  3JX7 A;  1I7W A;  5EKG A;  4GMO A;  3UKZ B;  5K9S A;  2Z5J A;  4B8J A;  3C2G A;  2BNX A;  4JW3 C;  3VLE A;  3EA5 B;  2PF4 A;  3ND2 A;  1QGR A;  4U54 A;  4CV5 B;  1EJL I;  4FFB C;  3A6P A;  3OPB A;  3Q0N A;  1T08 A;  4ZDU A;  5KUB A;  4CT6 B;  3OBV A;  3Q0M A;  4NEE A;  1Q1S C;  5CL5 A;  5CTT A;  5E6Q B;  4V3R A;  4B18 A;  2W3C A;  4MZ6 E;  3UL0 B;  1I7X A;  4V3O A;  3TJZ B;  4A0C A;  3V71 A;  3K7W A;  3GAE A;  3V74 A;  5JJA A;  1M8Z A;  3LTJ A;  5H2W A;  3QGB A;  4CB8 A;  2IE4 A;  5LSW A;  3K62 A;  2IE3 A;  4KZG A;  3Q0S A;  3QML C;  3TT9 A;  3ZIP A;  3SLA A;  3UJ4 A;  4MFU A;  4U3J C;  1BK5 A;  3QHE A;  1XQR A;  1Y2A C;  4I96 A;  4DJS A;  5CL8 A;  4L4I A;  5HUY C;  5SW9 A;  4DB9 A;  4UAD A;  3ZIO A;  2QK2 A;  2BCT A;  2VGL A;  5H2X A;  4UAF B;  2IAE B;  3ZIR A;  4EVP A;  3ZIL A;  5CL4 A;  4YGX A;  2NYM B;  1WA5 C;  5BYM A;  4OIH A;  1G3J A;  3TPM A;  4JKQ A;  3WPT A;  3GQ2 A;  3L6Y A;  3JY1 A;  3ZKV A;  1IQ1 C;  1IB2 A;  1F59 A;  4QMH A;  3BX3 A;  4D49 A;  4CRU B;  4RV1 A;  1V18 A;  4R11 A;  4H3K A;  2RU4 B;  5B56 A;  5CLA A;  4BPL A;  1LUJ A;  4FQ3 A;  4I3N A;  4TNM A;  5BZ1 A;  2JKT A;  3FEY C;  1EE4 A;  3K64 A;  2OF3 A;  1BK6 A;  4HNM A;  4U2X D;  3GVO A;  3O2S A;  1U6G C;  2XA7 A;  4E4V A;  1OYZ A;  4CRV B;  5BZU A;  2Z6H A;  4FP7 A;  4XZR B;  3JXZ A;  3DAD A;  3QG9 A;  1HO8 A;  4NZW A;  2NYL A;  5CLC A;  4I8M A;  4I2W A;  1TE4 A;  4U5S A;  3ZIK A;  3BSX A;  5CLB A;  3K4E A;  4I0Y A;  2Z5K A;  4P6Z B;  1EJY I;  4PLQ A;  3EBB A;  4A3T A;  4QMJ A;  3O2Q A;  2NPP A;  3O4X A;  2QMR A;  1M1E A;  3Q0O A;  3NOW A;  4L4H A;  1Z2C B;  1JDH A;  1QBK B;  4CT7 B;  4HM9 A;  3ODR A;  2XOA A;  4YK6 A;  2JDQ A;  2YNS A;  2WTK A;  3C2H A;  3GB8 A;  3WOZ A;  4PLR A;  2YJY A;  4MFV A;  3PST A;  3BCT A;  2PKG A;  3K5Y A;  4A3V A;  4FDD A;  3K5Z A;  4EV8 A;  2VGL B;  4I37 A;  3KND A;  2C1T A;  4O27 A;  4I2Z A;  3TJ3 A;  3TPO A;  4QMI A;  5CL9 A;  4U58 A;  5EKF A;  1JPP A;  1W63 B;  2Z6G A;  4CB9 A;  4I2S A;  1GCJ A;  1QZ7 A;  3WOY A;  4UQI A;  4B8P A;  1M8Y A;  3VLF A;  4V3Q A;  4YJE A;  5CL6 A;  2JKR B;  5CLE A;  3Q0P A;  2BKU B;  3Q5U A;  4G3A A;  4D4E A;  3IFQ A;  3T7U A;  3JXY A;  5DN7 A;  5BZ5 A;  3QGC A;  4PLS A;  5K6S A;  3L3Q A;  2JKT B;  1W9C A;  3FGA B;  4I1E A;  3UKY B;  3GVT A;  4MZ5 E;  3NMX A;  4EVT A;  4OO6 A;  3BX2 A;  2YNR A;  3PSP A;  3ZIQ A;  3VWA A;  4GMN A;  3GS3 A;  1PJN B;  4EV9 A;  4JLQ A;  4U5L A;  4Y5J A;  2IW3 A;  1JPW A;  3TX7 A;  2NYL B;  3ZIN A;  2OT8 A;  4RZP A;  5SWF A;  3Q0R A;  4H3H A;  3NMZ A;  5KLT B;  3L6X A;  2C1M A;  2IAE A;  2Q5D A;  1LSH A;  3DW8 A;  1IAL A;  2NPP B;  3O2T A;  3BTR C;  4WV6 A;  1XQS A;  5BZV A;  2NYM A;  3K49 A;  4JW2 A;  2JAK A;  1IBR B;  2BAP A;  1M5N S;  3RZ9 A;  4I6I A;  3EG5 B;  3L3F X;  1B3U A;  1Q1T C;  2H4M A;  4DB6 A;  5FC8 E;  1TH1 A;  4U5N A;  4K92 A;  3ZHP A;  3OUW A;  2RU4 A;  3BWT A;  2Z5N A;  4DB8 A;  2P8Q A;  3BSB A;  5CL3 A;  4I5N A;  3UL1 B;  5CL7 A;  3BVS A;  4UQI B;  1UKL A;  1XM9 A;  3W3U A;  4CBA A;  2X1G F;  3UVU A;  1UN0 A;  5KLA A;  4I7I A;  4HXT A;  4DVG B;  3VLD A;  3ODS A;  4DBA A;  4YJL A;  4BQK A; 
#chains in the Genus database with same CATH homology
 4FZD A;  1EE5 A;  4I5L A;  4L7M A;  1UPK A;  4PVZ A;  4U5U A;  1M8X A;  3NMW A;  3LWW A;  2GL7 A;  2Z5M A;  4YI0 C;  4ADY A;  3UKX B;  3Q0L A;  4UAE A;  5D5K C;  3Q0Q A;  4IMJ A;  2F31 A;  2IWH A;  1PJM B;  3UKW B;  3C5W A;  4U5V A;  4FZA A;  4R10 A;  4IMI A;  3LTM A;  1QGK A;  3AU3 A;  5AEI A;  2FV2 A;  1O6P A;  4DZS A;  5SVZ A;  3WYF C;  4B8O A;  3SL9 A;  4FZF A;  5CLD A;  3OUX A;  5HHG E;  4RXH B;  5EWP A;  5KL1 A;  1WA5 B;  4EVA A;  1M8W A;  4BA3 A;  2XA7 B;  3V6Y A;  1UPL A;  1W63 A;  3IBV A;  2QK1 A;  4R0Z A;  4JW2 B;  2X19 B;  3K7V A;  2IX3 A;  4U5O A;  3H3D X;  2JKR A;  5HUW C;  2DB0 A;  1O6O A;  3K5Q A;  3FEX C;  3GNI A;  5J3V A;  2QNA A;  2Z5O A;  3VE6 A;  5KLR B;  4P6Z G;  3RZX A;  3OQS A;  4LAC A;  3K61 A;  1LRV A;  3FGA A;  5KL8 A;  4UWX A;  4HTV A;  4K6J A;  3GRL A;  3JX7 A;  1I7W A;  5EKG A;  4GMO A;  3UKZ B;  5K9S A;  2Z5J A;  4B8J A;  3C2G A;  2BNX A;  4JW3 C;  3VLE A;  3EA5 B;  2PF4 A;  3ND2 A;  1QGR A;  4U54 A;  4CV5 B;  1EJL I;  4FFB C;  3A6P A;  3OPB A;  3Q0N A;  1T08 A;  4ZDU A;  5KUB A;  4CT6 B;  3OBV A;  3Q0M A;  4NEE A;  1Q1S C;  5CL5 A;  5CTT A;  5E6Q B;  4V3R A;  4B18 A;  2W3C A;  4MZ6 E;  3UL0 B;  1I7X A;  4V3O A;  3TJZ B;  4A0C A;  3V71 A;  3K7W A;  3GAE A;  3V74 A;  5JJA A;  1M8Z A;  3LTJ A;  5H2W A;  3QGB A;  4CB8 A;  2IE4 A;  5LSW A;  3K62 A;  2IE3 A;  4KZG A;  3Q0S A;  3QML C;  3TT9 A;  3ZIP A;  3SLA A;  4MFU A;  4U3J C;  1BK5 A;  3QHE A;  1XQR A;  1Y2A C;  4I96 A;  4DJS A;  5CL8 A;  4L4I A;  5HUY C;  5SW9 A;  4DB9 A;  4UAD A;  3ZIO A;  2QK2 A;  2BCT A;  2VGL A;  5H2X A;  4UAF B;  2IAE B;  3ZIR A;  4EVP A;  3ZIL A;  5CL4 A;  4YGX A;  2NYM B;  1WA5 C;  5BYM A;  4OIH A;  1G3J A;  3TPM A;  4JKQ A;  3WPT A;  3GQ2 A;  3L6Y A;  3JY1 A;  3ZKV A;  1IQ1 C;  1IB2 A;  1F59 A;  4QMH A;  3BX3 A;  4D49 A;  4CRU B;  4RV1 A;  1V18 A;  4R11 A;  4H3K A;  2RU4 B;  5B56 A;  5CLA A;  4BPL A;  1LUJ A;  4FQ3 A;  4I3N A;  4TNM A;  5BZ1 A;  2JKT A;  3FEY C;  1EE4 A;  3K64 A;  2OF3 A;  1BK6 A;  4HNM A;  4U2X D;  3GVO A;  3O2S A;  1U6G C;  2XA7 A;  4E4V A;  1OYZ A;  4CRV B;  5BZU A;  2Z6H A;  4FP7 A;  4XZR B;  3JXZ A;  3DAD A;  3QG9 A;  1HO8 A;  4NZW A;  2NYL A;  5CLC A;  4I8M A;  4I2W A;  1TE4 A;  4U5S A;  3ZIK A;  3BSX A;  5CLB A;  3K4E A;  4I0Y A;  2Z5K A;  4P6Z B;  1EJY I;  4PLQ A;  3EBB A;  4A3T A;  4QMJ A;  3O2Q A;  2NPP A;  3O4X A;  2QMR A;  1M1E A;  3Q0O A;  3NOW A;  4L4H A;  1Z2C B;  1JDH A;  1QBK B;  4CT7 B;  4HM9 A;  3ODR A;  2XOA A;  4YK6 A;  2JDQ A;  2YNS A;  2WTK A;  3C2H A;  3GB8 A;  3WOZ A;  4PLR A;  2YJY A;  4MFV A;  3PST A;  3BCT A;  2PKG A;  3K5Y A;  4A3V A;  4FDD A;  3K5Z A;  4EV8 A;  2VGL B;  4I37 A;  3KND A;  2C1T A;  4O27 A;  4I2Z A;  3TJ3 A;  3TPO A;  4QMI A;  5CL9 A;  4U58 A;  5EKF A;  1JPP A;  1W63 B;  2Z6G A;  4CB9 A;  4I2S A;  1GCJ A;  1QZ7 A;  3WOY A;  4UQI A;  4B8P A;  1M8Y A;  3VLF A;  4V3Q A;  4YJE A;  5CL6 A;  2JKR B;  5CLE A;  3Q0P A;  2BKU B;  3Q5U A;  4G3A A;  4D4E A;  3IFQ A;  3T7U A;  3JXY A;  5DN7 A;  5BZ5 A;  3QGC A;  4PLS A;  5K6S A;  3L3Q A;  2JKT B;  1W9C A;  3FGA B;  4I1E A;  3UKY B;  3GVT A;  4MZ5 E;  3NMX A;  4EVT A;  4OO6 A;  3BX2 A;  2YNR A;  3PSP A;  3ZIQ A;  3VWA A;  4GMN A;  3GS3 A;  1PJN B;  4EV9 A;  4JLQ A;  4U5L A;  4Y5J A;  2IW3 A;  1JPW A;  3TX7 A;  2NYL B;  3ZIN A;  2OT8 A;  4RZP A;  5SWF A;  3Q0R A;  4H3H A;  3NMZ A;  5KLT B;  3L6X A;  2C1M A;  2IAE A;  2Q5D A;  3DW8 A;  1IAL A;  2NPP B;  3O2T A;  3BTR C;  4WV6 A;  1XQS A;  5BZV A;  2NYM A;  3K49 A;  4JW2 A;  2JAK A;  1IBR B;  2BAP A;  1M5N S;  3RZ9 A;  4I6I A;  3EG5 B;  3L3F X;  1B3U A;  1Q1T C;  2H4M A;  4DB6 A;  5FC8 E;  1TH1 A;  4U5N A;  4K92 A;  3ZHP A;  3OUW A;  2RU4 A;  3BWT A;  2Z5N A;  4DB8 A;  2P8Q A;  3BSB A;  5CL3 A;  4I5N A;  3UL1 B;  5CL7 A;  3BVS A;  4UQI B;  1UKL A;  1XM9 A;  3W3U A;  4CBA A;  2X1G F;  3UVU A;  1UN0 A;  5KLA A;  4I7I A;  4HXT A;  4DVG B;  3VLD A;  3ODS A;  4DBA A;  4YJL A;  4BQK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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