4USGA

Crystal structure of pc4 w89y mutant complex with dna
Total Genus 16
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
16
sequence length
66
structure length
66
Chain Sequence
AMFQIGKMRYVSVRDFKGKVLIDIREYYMDPEGEMKPGRKGISLNPEQWSQLKEQISDIDDAVRKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15
publication title Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4.
pubmed doi rcsb
source organism Homo sapiens
total genus 16
structure length 66
sequence length 66
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-07-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02229 PC4 Transcriptional Coactivator p15 (PC4)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.30.31.10 Mainly Beta Roll Transcriptional Co-activator pc4; Chain A Transcriptional Coactivator Pc4; Chain A 4usgA00
1L3AA 2NVNA 4KOOA 3RA0A 2PHEA 4KOPA 3R9ZA 4AGHA 3N1HA 3N1IA 2C62A 3N1LA 4KOQA 4BG7A 3R9YA 4BHMA 3N1KA 2IT9A 3N1JA 4USGA 1PCFA
chains in the Genus database with same CATH superfamily
3K44A 3CM1A 2GJED 1L3AA 2NVNA 4KOOA 4BXMA 3RA0A 2GJEA 2GIDB 2PHEA 4KOPA 3R9ZA 4AGHA 4BODA 3OBHA 3N1HA 3N1IA 4J38A 2C62A 3N1LA 2GIAB 4KOQA 4BG7A 2M4FA 3MTVA 1PCFA 3R9YA 5FGPA 4BF3A 2GIDA 4BOBA 4BHMA 3N1KA 2IT9A 3N1JA 4USGA 2GIAA
chains in the Genus database with same CATH topology
1L3AA 2NVNA 4KOOA 3RA0A 2PHEA 4KOPA 3R9ZA 4AGHA 3N1HA 3N1IA 2C62A 3N1LA 4KOQA 4BG7A 3R9YA 4BHMA 3N1KA 2IT9A 3N1JA 4USGA 1PCFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1L3A A;  2NVN A;  4KOO A;  3RA0 A;  2PHE A;  4KOP A;  3R9Z A;  4AGH A;  3N1H A;  3N1I A;  2C62 A;  3N1L A;  4KOQ A;  4BG7 A;  3R9Y A;  4BHM A;  3N1K A;  2IT9 A;  3N1J A;  4USG A;  1PCF A; 
#chains in the Genus database with same CATH topology
 3K44 A;  3CM1 A;  2GJE D;  1L3A A;  2NVN A;  4KOO A;  4BXM A;  3RA0 A;  2GJE A;  2GID B;  2PHE A;  4KOP A;  3R9Z A;  4AGH A;  4BOD A;  3OBH A;  3N1H A;  3N1I A;  4J38 A;  2C62 A;  3N1L A;  2GIA B;  4KOQ A;  4BG7 A;  2M4F A;  3MTV A;  1PCF A;  3R9Y A;  5FGP A;  4BF3 A;  2GID A;  4BOB A;  4BHM A;  3N1K A;  2IT9 A;  3N1J A;  4USG A;  2GIA A; 
#chains in the Genus database with same CATH homology
 1L3A A;  2NVN A;  4KOO A;  3RA0 A;  2PHE A;  4KOP A;  3R9Z A;  4AGH A;  3N1H A;  3N1I A;  2C62 A;  3N1L A;  4KOQ A;  4BG7 A;  3R9Y A;  4BHM A;  3N1K A;  2IT9 A;  3N1J A;  4USG A;  1PCF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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