4V0WA

The crystal structure of mouse pp1g in complex with truncated human ppp1r15b (631-669)
Total Genus 111
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
111
sequence length
295
structure length
295
Chain Sequence
MLNIDSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPDKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKPAE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
pubmed doi rcsb
molecule keywords SERINE/THREONINE-PROTEIN PHOSPHATASE PP1-GAMMA CATALYTIC SUB
molecule tags Hydrolase/hydrolase regulator
source organism Mus musculus
total genus 111
structure length 295
sequence length 295
chains with identical sequence C
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2014-09-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00149 Metallophos Calcineurin-like phosphoesterase
A PF16891 STPPase_N Serine-threonine protein phosphatase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.60.21.10 Alpha Beta 4-Layer Sandwich Purple Acid Phosphatase; chain A, domain 2 Purple Acid Phosphatase; chain A, domain 2 4v0wA00
2QFRA 4FBWA 3EGHA 3AV0A 1II7A 4FCXA 1S3LA 3PSOA 1KBPA 4TUIA 3AUZA 1XZWA 5JPEA 3K7WC 2WDEA 2WDCA 1M63A 1S70A 4H2IA 4I5NC 1HO5A 4JA9A 4LTYA 1OIEA 2P6BA 4Q7FA 2CV9A 1USHA 3RL3A 1NNWA 2Z72A 3H66A 3IB7A 4FBKA 4WWLA 3V4YA 2NPPC 4DSYA 2DFJA 3PSNA 3QG5C 2O8GA 4V0WA 3DW8C 3QFOA 4XPNA 2WDDA 3H60A 3H64A 3IB8A 4ZVZA 1V73A 4ORAA 2NXFA 5C1VA 2BDXA 1QHWA 2NYLC 4H1SA 4V0XA 4H1YP 4O24A 2BCDA 3RQZA 1OIDA 3E7AA 3LL8A 2KKNA 4IL1A 5JJTA 3H61A 4O4KA 3ZU0A 1IT6A 3THOB 2GJUA 3JYFA 2O8AA 2YVTA 3C9FA 3DSCA 4DHLA 1Z2XA 3N5UA 3EGGA 3THNA 1UTEA 1S8EA 3H67A 3RL5A 4UWQA 2Z1AA 4HD0A 1UF3A 2QFPA 3TGHA 1G5BA 2IE4C 4DT2A 4UT3B 4H2FA 2BQ8X 4G9JA 5GTUA 4KKZA 1S3MA 5INBA 1WARA 1TCOA 4UT3A 4J6OA 3T1IA 3IVEA 1U32A 4TUGA 1W24A 5JPFA 2A22A 3FGAC 3E7BA 2Q8UA 2HYOA 5DNYA 3QFMA 1Z2WA 2WDFA 4IYPC 2IE3C 4JA7A 3ICFA 3P71C 4B2OA 1HPUA 4MOYA 3CK2A 4O43A 4YKEA 2IAEC 3IVDA 2XMOA 2JOGA 3H69A 2R17A 3QFKA 4UT2A 1WAO1 3HVQA 3KBPA 2HY1A 3GVEA 4LACC 3RL4A 4KBPA 5EQVA 3H68A 1S3NA 1AUIA 4NZVA 4OR9A 4ORBA 4ORCA 1T71A 5IOHA 2AHDA 4H2BA 2NYMC 4O5GA 3QFNA 3C5WC 3H63A 3H62B 1MF8A 1XM7A 5J28A 4LU9A 1FJMA 1HP1A 1SU1A 5HPEA 3DSDA 1OI8A 2ZBMA 1QFCA 2QJCA 4MOVA 4F0ZA 3ZTVA 4M0VA 3K7VC 4ZX2A 5F3WA 5B8IA 2Z06A 4FBQA 2USHA 2HYPA 4H2GA 1S95A 4I5LC 1JK7A 4V0VA 1T70A 4MP0A
chains in the Genus database with same CATH superfamily
2QFRA 4FBWA 3EGHA 3AV0A 1II7A 4FCXA 1S3LA 3PSOA 1KBPA 4TUIA 3AUZA 1XZWA 5JPEA 2YEQA 2WDEA 2WDCA 1M63A 1S70A 3K7WC 4H2IA 1HO5A 4I5NC 4JA9A 4LTYA 1OIEA 2P6BA 4Q7FA 2CV9A 1USHA 3RL3A 1NNWA 2Z72A 3H66A 3IB7A 4FBKA 4WWLA 3V4YA 2NPPC 4DSYA 2DFJA 3PSNA 3QG5C 2O8GA 4V0WA 3DW8C 3QFOA 4XPNA 2WDDA 3H60A 3H64A 3IB8A 4ZVZA 1V73A 4ORAA 2NXFA 5C1VA 2BDXA 1QHWA 2NYLC 4H1SA 4V0XA 4H1YP 4O24A 2BCDA 2ZOAA 3RQZA 1OIDA 3E7AA 3LL8A 2KKNA 4IL1A 3D03A 3H61A 5JJTA 4O4KA 3ZU0A 1IT6A 3THOB 2GJUA 3JYFA 2O8AA 2YVTA 3C9FA 3DSCA 4DHLA 1Z2XA 3N5UA 3EGGA 3THNA 1UTEA 1S8EA 3H67A 3RL5A 4UWQA 2Z1AA 4HD0A 1UF3A 2QFPA 3TGHA 1G5BA 2IE4C 4DT2A 4UT3B 4H2FA 2BQ8X 4G9JA 5GTUA 4KKZA 1S3MA 5INBA 1WARA 1TCOA 4UT3A 4J6OA 3T1IA 3IVEA 1U32A 4TUGA 1W24A 5JPFA 2A22A 3FGAC 3E7BA 2Q8UA 2HYOA 5DNYA 3QFMA 1Z2WA 2WDFA 4IYPC 2IE3C 4JA7A 3ICFA 3P71C 4B2OA 1HPUA 4MOYA 3CK2A 4O43A 4YKEA 2ZO9B 2IAEC 3IVDA 2XMOA 2JOGA 3H69A 2R17A 3QFKA 4UT2A 1WAO1 3HVQA 3KBPA 2HY1A 3GVEA 4LACC 3FLOA 2DXLA 3E0JA 4KBPA 5EQVA 3H68A 3RL4A 1S3NA 1AUIA 2DXNA 4NZVA 4OR9A 4ORBA 4ORCA 1T71A 5IOHA 2AHDA 4H2BA 2NYMC 4O5GA 3QFNA 3C5WC 3H63A 3H62B 1MF8A 1XM7A 5J28A 4LU9A 1FJMA 1HP1A 1SU1A 5HPEA 3DSDA 1OI8A 2ZBMA 1QFCA 2QJCA 4MOVA 4F0ZA 3ZTVA 4M0VA 3K7VC 4ZX2A 5F3WA 5B8IA 2Z06A 4FBQA 2USHA 2HYPA 4H2GA 1S95A 4I5LC 1JK7A 4V0VA 1T70A 4MP0A
chains in the Genus database with same CATH topology
2QFRA 4FBWA 3EGHA 3AV0A 1II7A 4FCXA 1S3LA 3PSOA 1KBPA 4TUIA 3AUZA 1XZWA 5JPEA 2YEQA 2WDEA 2WDCA 1M63A 1S70A 3K7WC 4H2IA 1HO5A 4I5NC 4JA9A 4LTYA 1OIEA 2P6BA 4Q7FA 2CV9A 1USHA 3RL3A 1NNWA 2Z72A 3H66A 3IB7A 4FBKA 4WWLA 3V4YA 2NPPC 4DSYA 2DFJA 3PSNA 3QG5C 2O8GA 4V0WA 3DW8C 3QFOA 4XPNA 2WDDA 3H60A 3H64A 3IB8A 4ZVZA 1V73A 4ORAA 2NXFA 5C1VA 2BDXA 1QHWA 2NYLC 4H1SA 4V0XA 4H1YP 4O24A 2BCDA 2ZOAA 3RQZA 1OIDA 3E7AA 3LL8A 2KKNA 4IL1A 3D03A 3H61A 5JJTA 4O4KA 3ZU0A 1IT6A 3THOB 2GJUA 3JYFA 2O8AA 2YVTA 3C9FA 3DSCA 4DHLA 1Z2XA 3N5UA 3EGGA 3THNA 1UTEA 1S8EA 3H67A 3RL5A 4UWQA 2Z1AA 4HD0A 1UF3A 2QFPA 3TGHA 1G5BA 2IE4C 4DT2A 4UT3B 4H2FA 2BQ8X 4G9JA 5GTUA 4KKZA 1S3MA 5INBA 1WARA 1TCOA 4UT3A 4J6OA 3T1IA 3IVEA 1U32A 4TUGA 1W24A 5JPFA 2A22A 3FGAC 3E7BA 2Q8UA 2HYOA 5DNYA 3QFMA 1Z2WA 2WDFA 4IYPC 2IE3C 4JA7A 3ICFA 3P71C 4B2OA 1HPUA 4MOYA 3CK2A 4O43A 4YKEA 2ZO9B 2IAEC 3IVDA 2XMOA 2JOGA 3H69A 2R17A 3QFKA 4UT2A 1WAO1 3HVQA 3KBPA 2HY1A 3GVEA 4LACC 3FLOA 2DXLA 3E0JA 4KBPA 5EQVA 3H68A 3RL4A 1S3NA 1AUIA 2DXNA 4NZVA 4OR9A 4ORBA 4ORCA 1T71A 5IOHA 2AHDA 4H2BA 2NYMC 4O5GA 3QFNA 3C5WC 3H63A 3H62B 1MF8A 1XM7A 5J28A 4LU9A 1FJMA 1HP1A 1SU1A 5HPEA 3DSDA 1OI8A 2ZBMA 1QFCA 2QJCA 4MOVA 4F0ZA 3ZTVA 4M0VA 3K7VC 4ZX2A 5F3WA 5B8IA 2Z06A 4FBQA 2USHA 2HYPA 4H2GA 1S95A 4I5LC 1JK7A 4V0VA 1T70A 4MP0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QFR A;  4FBW A;  3EGH A;  3AV0 A;  1II7 A;  4FCX A;  1S3L A;  3PSO A;  1KBP A;  4TUI A;  3AUZ A;  1XZW A;  5JPE A;  3K7W C;  2WDE A;  2WDC A;  1M63 A;  1S70 A;  4H2I A;  4I5N C;  1HO5 A;  4JA9 A;  4LTY A;  1OIE A;  2P6B A;  4Q7F A;  2CV9 A;  1USH A;  3RL3 A;  1NNW A;  2Z72 A;  3H66 A;  3IB7 A;  4FBK A;  4WWL A;  3V4Y A;  2NPP C;  4DSY A;  2DFJ A;  3PSN A;  3QG5 C;  2O8G A;  4V0W A;  3DW8 C;  3QFO A;  4XPN A;  2WDD A;  3H60 A;  3H64 A;  3IB8 A;  4ZVZ A;  1V73 A;  4ORA A;  2NXF A;  5C1V A;  2BDX A;  1QHW A;  2NYL C;  4H1S A;  4V0X A;  4H1Y P;  4O24 A;  2BCD A;  3RQZ A;  1OID A;  3E7A A;  3LL8 A;  2KKN A;  4IL1 A;  5JJT A;  3H61 A;  4O4K A;  3ZU0 A;  1IT6 A;  3THO B;  2GJU A;  3JYF A;  2O8A A;  2YVT A;  3C9F A;  3DSC A;  4DHL A;  1Z2X A;  3N5U A;  3EGG A;  3THN A;  1UTE A;  1S8E A;  3H67 A;  3RL5 A;  4UWQ A;  2Z1A A;  4HD0 A;  1UF3 A;  2QFP A;  3TGH A;  1G5B A;  2IE4 C;  4DT2 A;  4UT3 B;  4H2F A;  2BQ8 X;  4G9J A;  5GTU A;  4KKZ A;  1S3M A;  5INB A;  1WAR A;  1TCO A;  4UT3 A;  4J6O A;  3T1I A;  3IVE A;  1U32 A;  4TUG A;  1W24 A;  5JPF A;  2A22 A;  3FGA C;  3E7B A;  2Q8U A;  2HYO A;  5DNY A;  3QFM A;  1Z2W A;  2WDF A;  4IYP C;  2IE3 C;  4JA7 A;  3ICF A;  3P71 C;  4B2O A;  1HPU A;  4MOY A;  3CK2 A;  4O43 A;  4YKE A;  2IAE C;  3IVD A;  2XMO A;  2JOG A;  3H69 A;  2R17 A;  3QFK A;  4UT2 A;  1WAO 1;  3HVQ A;  3KBP A;  2HY1 A;  3GVE A;  4LAC C;  3RL4 A;  4KBP A;  5EQV A;  3H68 A;  1S3N A;  1AUI A;  4NZV A;  4OR9 A;  4ORB A;  4ORC A;  1T71 A;  5IOH A;  2AHD A;  4H2B A;  2NYM C;  4O5G A;  3QFN A;  3C5W C;  3H63 A;  3H62 B;  1MF8 A;  1XM7 A;  5J28 A;  4LU9 A;  1FJM A;  1HP1 A;  1SU1 A;  5HPE A;  3DSD A;  1OI8 A;  2ZBM A;  1QFC A;  2QJC A;  4MOV A;  4F0Z A;  3ZTV A;  4M0V A;  3K7V C;  4ZX2 A;  5F3W A;  5B8I A;  2Z06 A;  4FBQ A;  2USH A;  2HYP A;  4H2G A;  1S95 A;  4I5L C;  1JK7 A;  4V0V A;  1T70 A;  4MP0 A; 
#chains in the Genus database with same CATH topology
 2QFR A;  4FBW A;  3EGH A;  3AV0 A;  1II7 A;  4FCX A;  1S3L A;  3PSO A;  1KBP A;  4TUI A;  3AUZ A;  1XZW A;  5JPE A;  2YEQ A;  2WDE A;  2WDC A;  1M63 A;  1S70 A;  3K7W C;  4H2I A;  1HO5 A;  4I5N C;  4JA9 A;  4LTY A;  1OIE A;  2P6B A;  4Q7F A;  2CV9 A;  1USH A;  3RL3 A;  1NNW A;  2Z72 A;  3H66 A;  3IB7 A;  4FBK A;  4WWL A;  3V4Y A;  2NPP C;  4DSY A;  2DFJ A;  3PSN A;  3QG5 C;  2O8G A;  4V0W A;  3DW8 C;  3QFO A;  4XPN A;  2WDD A;  3H60 A;  3H64 A;  3IB8 A;  4ZVZ A;  1V73 A;  4ORA A;  2NXF A;  5C1V A;  2BDX A;  1QHW A;  2NYL C;  4H1S A;  4V0X A;  4H1Y P;  4O24 A;  2BCD A;  2ZOA A;  3RQZ A;  1OID A;  3E7A A;  3LL8 A;  2KKN A;  4IL1 A;  3D03 A;  3H61 A;  5JJT A;  4O4K A;  3ZU0 A;  1IT6 A;  3THO B;  2GJU A;  3JYF A;  2O8A A;  2YVT A;  3C9F A;  3DSC A;  4DHL A;  1Z2X A;  3N5U A;  3EGG A;  3THN A;  1UTE A;  1S8E A;  3H67 A;  3RL5 A;  4UWQ A;  2Z1A A;  4HD0 A;  1UF3 A;  2QFP A;  3TGH A;  1G5B A;  2IE4 C;  4DT2 A;  4UT3 B;  4H2F A;  2BQ8 X;  4G9J A;  5GTU A;  4KKZ A;  1S3M A;  5INB A;  1WAR A;  1TCO A;  4UT3 A;  4J6O A;  3T1I A;  3IVE A;  1U32 A;  4TUG A;  1W24 A;  5JPF A;  2A22 A;  3FGA C;  3E7B A;  2Q8U A;  2HYO A;  5DNY A;  3QFM A;  1Z2W A;  2WDF A;  4IYP C;  2IE3 C;  4JA7 A;  3ICF A;  3P71 C;  4B2O A;  1HPU A;  4MOY A;  3CK2 A;  4O43 A;  4YKE A;  2ZO9 B;  2IAE C;  3IVD A;  2XMO A;  2JOG A;  3H69 A;  2R17 A;  3QFK A;  4UT2 A;  1WAO 1;  3HVQ A;  3KBP A;  2HY1 A;  3GVE A;  4LAC C;  3FLO A;  2DXL A;  3E0J A;  4KBP A;  5EQV A;  3H68 A;  3RL4 A;  1S3N A;  1AUI A;  2DXN A;  4NZV A;  4OR9 A;  4ORB A;  4ORC A;  1T71 A;  5IOH A;  2AHD A;  4H2B A;  2NYM C;  4O5G A;  3QFN A;  3C5W C;  3H63 A;  3H62 B;  1MF8 A;  1XM7 A;  5J28 A;  4LU9 A;  1FJM A;  1HP1 A;  1SU1 A;  5HPE A;  3DSD A;  1OI8 A;  2ZBM A;  1QFC A;  2QJC A;  4MOV A;  4F0Z A;  3ZTV A;  4M0V A;  3K7V C;  4ZX2 A;  5F3W A;  5B8I A;  2Z06 A;  4FBQ A;  2USH A;  2HYP A;  4H2G A;  1S95 A;  4I5L C;  1JK7 A;  4V0V A;  1T70 A;  4MP0 A; 
#chains in the Genus database with same CATH homology
 2QFR A;  4FBW A;  3EGH A;  3AV0 A;  1II7 A;  4FCX A;  1S3L A;  3PSO A;  1KBP A;  4TUI A;  3AUZ A;  1XZW A;  5JPE A;  2YEQ A;  2WDE A;  2WDC A;  1M63 A;  1S70 A;  3K7W C;  4H2I A;  1HO5 A;  4I5N C;  4JA9 A;  4LTY A;  1OIE A;  2P6B A;  4Q7F A;  2CV9 A;  1USH A;  3RL3 A;  1NNW A;  2Z72 A;  3H66 A;  3IB7 A;  4FBK A;  4WWL A;  3V4Y A;  2NPP C;  4DSY A;  2DFJ A;  3PSN A;  3QG5 C;  2O8G A;  4V0W A;  3DW8 C;  3QFO A;  4XPN A;  2WDD A;  3H60 A;  3H64 A;  3IB8 A;  4ZVZ A;  1V73 A;  4ORA A;  2NXF A;  5C1V A;  2BDX A;  1QHW A;  2NYL C;  4H1S A;  4V0X A;  4H1Y P;  4O24 A;  2BCD A;  2ZOA A;  3RQZ A;  1OID A;  3E7A A;  3LL8 A;  2KKN A;  4IL1 A;  3D03 A;  3H61 A;  5JJT A;  4O4K A;  3ZU0 A;  1IT6 A;  3THO B;  2GJU A;  3JYF A;  2O8A A;  2YVT A;  3C9F A;  3DSC A;  4DHL A;  1Z2X A;  3N5U A;  3EGG A;  3THN A;  1UTE A;  1S8E A;  3H67 A;  3RL5 A;  4UWQ A;  2Z1A A;  4HD0 A;  1UF3 A;  2QFP A;  3TGH A;  1G5B A;  2IE4 C;  4DT2 A;  4UT3 B;  4H2F A;  2BQ8 X;  4G9J A;  5GTU A;  4KKZ A;  1S3M A;  5INB A;  1WAR A;  1TCO A;  4UT3 A;  4J6O A;  3T1I A;  3IVE A;  1U32 A;  4TUG A;  1W24 A;  5JPF A;  2A22 A;  3FGA C;  3E7B A;  2Q8U A;  2HYO A;  5DNY A;  3QFM A;  1Z2W A;  2WDF A;  4IYP C;  2IE3 C;  4JA7 A;  3ICF A;  3P71 C;  4B2O A;  1HPU A;  4MOY A;  3CK2 A;  4O43 A;  4YKE A;  2ZO9 B;  2IAE C;  3IVD A;  2XMO A;  2JOG A;  3H69 A;  2R17 A;  3QFK A;  4UT2 A;  1WAO 1;  3HVQ A;  3KBP A;  2HY1 A;  3GVE A;  4LAC C;  3FLO A;  2DXL A;  3E0J A;  4KBP A;  5EQV A;  3H68 A;  3RL4 A;  1S3N A;  1AUI A;  2DXN A;  4NZV A;  4OR9 A;  4ORB A;  4ORC A;  1T71 A;  5IOH A;  2AHD A;  4H2B A;  2NYM C;  4O5G A;  3QFN A;  3C5W C;  3H63 A;  3H62 B;  1MF8 A;  1XM7 A;  5J28 A;  4LU9 A;  1FJM A;  1HP1 A;  1SU1 A;  5HPE A;  3DSD A;  1OI8 A;  2ZBM A;  1QFC A;  2QJC A;  4MOV A;  4F0Z A;  3ZTV A;  4M0V A;  3K7V C;  4ZX2 A;  5F3W A;  5B8I A;  2Z06 A;  4FBQ A;  2USH A;  2HYP A;  4H2G A;  1S95 A;  4I5L C;  1JK7 A;  4V0V A;  1T70 A;  4MP0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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