4V31A

Cereblon isoform 4 from magnetospirillum gryphiswaldense in complex with deoxyuridine
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
111
structure length
111
Chain Sequence
MVLAPGASIFRCRQCGQTISRRDWLLPMGGDHEHVVFNPAGMIFRVWCFSLAQGLRLIGAPSGEFSWFKGYDWTIALCGQCGSHLGWHYEGGSQPQTFFGLIKDRLAEGPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Signaling protein
molecule keywords CEREBLON ISOFORM 4
publication title Thalidomide Mimics Uridine Binding to an Aromatic Cage in Cereblon.
pubmed doi rcsb
source organism Magnetospirillum gryphiswaldense
total genus 23
structure length 111
sequence length 111
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2014-10-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.150.20 Mainly Beta Beta Complex Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A Peptide methionine sulfoxide reductase. 4v31A00
3HCJA 4TZUA 3CEZA 4V30A 4V2ZA 2KZNA 4TZCA 3HCHA 3MAOA 4TZ4C 4CI2B 5AMHA 3E0OA 2K8DA 3WX2A 2KV1A 3HCIA 1L1DA 4CI1B 4CI3B 3WX1A 4V2YA 4V31A 3E0MA 3HCGA 3CXKA
chains in the Genus database with same CATH superfamily
1H6QA 2LVLA 3NCUA 3HCJA 4TZUA 3ZD6A 3CEZA 4V30A 4V2ZA 2KZNA 4A2XA 5E3HA 4TZCA 3EBMA 3GA3A 5F98A 2RMJA 3HCHA 2FU5A 3LRNA 3MAOA 3ZD7A 2RQAA 2KWBA 3P3KA 4TZ4C 3LRRA 4CI2B 2W4RA 5AMHA 3EQTA 3E0OA 5F9HA 2K8DA 3WX2A 2RQBA 2HR9A 3DJMA 4A2VA 2KV1A 3HCIA 1TXJA 3FACA 1YZ1A 1L1DA 2QFDA 4CI1B 2YKGA 4BPBA 3OG8A 4AY2A 2LOYA 4CI3B 3WX1A 4V2YA 1FWQA 1H7YA 1HXRA 4V31A 3E0MA 3HCGA 3CXKA 2QFBA 5F9FA
chains in the Genus database with same CATH topology
3HCJA 4TZUA 3CEZA 4V30A 4V2ZA 2KZNA 4TZCA 3HCHA 3MAOA 4TZ4C 4CI2B 5AMHA 3E0OA 2K8DA 3WX2A 2KV1A 3HCIA 1L1DA 4CI1B 4CI3B 3WX1A 4V2YA 4V31A 3E0MA 3HCGA 3CXKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HCJ A;  4TZU A;  3CEZ A;  4V30 A;  4V2Z A;  2KZN A;  4TZC A;  3HCH A;  3MAO A;  4TZ4 C;  4CI2 B;  5AMH A;  3E0O A;  2K8D A;  3WX2 A;  2KV1 A;  3HCI A;  1L1D A;  4CI1 B;  4CI3 B;  3WX1 A;  4V2Y A;  4V31 A;  3E0M A;  3HCG A;  3CXK A; 
#chains in the Genus database with same CATH topology
 1H6Q A;  2LVL A;  3NCU A;  3HCJ A;  4TZU A;  3ZD6 A;  3CEZ A;  4V30 A;  4V2Z A;  2KZN A;  4A2X A;  5E3H A;  4TZC A;  3EBM A;  3GA3 A;  5F98 A;  2RMJ A;  3HCH A;  2FU5 A;  3LRN A;  3MAO A;  3ZD7 A;  2RQA A;  2KWB A;  3P3K A;  4TZ4 C;  3LRR A;  4CI2 B;  2W4R A;  5AMH A;  3EQT A;  3E0O A;  5F9H A;  2K8D A;  3WX2 A;  2RQB A;  2HR9 A;  3DJM A;  4A2V A;  2KV1 A;  3HCI A;  1TXJ A;  3FAC A;  1YZ1 A;  1L1D A;  2QFD A;  4CI1 B;  2YKG A;  4BPB A;  3OG8 A;  4AY2 A;  2LOY A;  4CI3 B;  3WX1 A;  4V2Y A;  1FWQ A;  1H7Y A;  1HXR A;  4V31 A;  3E0M A;  3HCG A;  3CXK A;  2QFB A;  5F9F A; 
#chains in the Genus database with same CATH homology
 3HCJ A;  4TZU A;  3CEZ A;  4V30 A;  4V2Z A;  2KZN A;  4TZC A;  3HCH A;  3MAO A;  4TZ4 C;  4CI2 B;  5AMH A;  3E0O A;  2K8D A;  3WX2 A;  2KV1 A;  3HCI A;  1L1D A;  4CI1 B;  4CI3 B;  3WX1 A;  4V2Y A;  4V31 A;  3E0M A;  3HCG A;  3CXK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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