4WFNS

Crystal structure of the large ribosomal subunit (50s) of deinococcus radiodurans containing a three residue insertion in l22 in complex with erythromycin
Total Genus 19
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
19
sequence length
175
structure length
175
Chain Sequence
MELTAKPRTPKQKLDESMIAAVAYNKENNVSFALDRKAFDRAFRQQSTTGLFDITVEGGETFPALVKAVQMDKRKRAPIHVDFYMVTYGEPVEVSVPVHTTGRSQGEVQGGLVDIVVHNLQIVAPGPRRIPQELVVDVTKMNIGDHITAGDIKLPEGCTLAADPELTVVSVLPPR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.
pubmed doi rcsb
molecule tags Ribosome
molecule keywords 50S ribosomal protein L2
total genus 19
structure length 175
sequence length 175
ec nomenclature
pdb deposition date 2014-09-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
S PF01386 Ribosomal_L25p Ribosomal L25p family
S PF14693 Ribosomal_TL5_C Ribosomal protein TL5, C-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.240.10 Mainly Beta Beta Barrel Ribosomal Protein L25; Chain P Ribosomal Protein L25; Chain P 4wfnS01
2.170.120.20 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 Ribosomal protein L25, beta domain 4wfnS02
5BNZA 4WCES 1QRUA 4IO9S 5DM6S 1O0BA 5IZNA 4WFNS 1QTQA 3J7ZV 1EXDA 1GTSA 1FEUA 4H3SA 5GAEW 2RE8A 3PIOS 5HL7S 2ZJQS 1D6KA 3PIPS 3DLLS 1NYLA 4JYZA 3AIIA 5GADW 2ZJPS 1O0CA 1EUQA 5GAHW 4UY88 2RD2A 4WF9S 4IOCS 1B75A 4IOAS 4U67S 4WFBS 2ZJRS 5JVHS 1QRSA 1GTRA 5JVGS 1EUYA 5DM7S 4P2BA 3CF5S 1DFUP 2HZ7A 4WFAS 1QRTA 4JXXA 5GAGW 4JXZA 1ZJWA
chains in the Genus database with same CATH superfamily
1TWGC 4ZH4A 1IW7A 1QRUA 5C4JC 2O5IA 2CX8A 4OIPA 5C4XC 3RZDC 2E2JC 3LYWA 4Q5SA 1EXDA 1GTSA 5IYBC 2KPUA 2RE8A 2B63C 3PIOS 5HL7S 3S1QC 2A6EA 3DLLS 1I50C 3CZBA 4MEXA 3S1MC 1O0CA 1EUQA 1TWCC 1YNNA 2KQ1A 5GAHW 4UY88 4L69A 4IOCS 4XLPA 5C44C 4A3JC 4A3IC 3S14C 4BBSC 4YG2A 1NXZA 4LK0A 2YU9C 3RZOC 2O5JA 3S2DC 1QRSA 2PJJA 2Y0SD 2R92C 4J3CA 4JK1A 4XSXA 1K83C 5C3EC 4P2BA 1I6HC 1Z85A 4G7HA 1ZYRA 4OIOA 2WB1D 1VHKA 4QIWD 3GTMC 5HQHA 3GTLC 1YNJA 1WCMC 4YFNA 1Y1VC 2CW0A 5BNZA 3X1LB 2NVYC 3M4OC 1O0BA 1HQMA 2BE5A 5TMCA 2WAQD 1FEUA 3K7AC 4H3SA 4BY1C 4XLNA 1D6KA 4MQ9A 3PIPS 1NYLA 3H3VD 4A3CC 4KN7A 3HOYC 4OINA 3M3YC 2VUMC 2G6GA 4A3BC 4LJZA 5IYDC 2RD2A 1I6VA 4WF9S 2JA6C 2PNWA 3DXJA 4X6AC 4C3HC 3KW2A 4U67S 4LK1A 5JVGS 4AYBD 3CQZC 1EUYA 5DM7S 4V194 1DFUP 2AE0X 2HZ7A 4A3LC 3HOWC 2EGWA 4WFAS 3S1NC 1V6ZA 3GTKC 1R9TC 4JXZA 3W2WB 3I4NC 4YFXA 2R7ZC 3HOVC 5TMFA 2GAEA 2PI8A 4IO9S 5DM6S 3EQLA 5IZNA 4YFKA 2EGVA 3HOXC 4A3MC 3S15C 1SMYA 5GAEW 4C3IC 1TWFC 3S17C 1Y1WC 2L3UA 4JYZA 3W2VB 3AIIA 3S2HC 2ZJPS 2NVXC 4C3JC 4H4KA 1VHYA 4BBRC 4A3FC 3S1RC 4KN4A 4E8BA 1B75A 2JA8C 2NVTC 4WFBS 5JVHS 1BDFA 4GZYA 3HOUC 1GTRA 5IYCC 2E2IC 2E2HC 3HOZC 4OIRA 3CF5S 3GTPC 3HKZD 2A6HA 4QJVA 4NOIA 2R93C 2G5DA 4MEYA 2PPBA 1TWAC 4Q4ZA 4LLGA 4WCES 1UDXA 1TWHC 4C2MC 4A3EC 4OIQA 4A3KC 3I4MC 3PO2C 4WFNS 1QTQA 2NVQC 3J7ZV 2JA5C 3PO3C 2NWAA 2ZJQS 2A69A 1I3QC 2KXYA 2PICA 3H0GC 5D4DA 3WODA 1SFOC 3S16C 2PA8D 3GTGC 4A3DC 4G7OA 2Z0YA 5GADW 2PMZD 5IP7C 4A93C 2L5NA 5IP9C 4Y52C 5FLMC 4KMUA 4Y7NC 3FKIC 4IOAS 2ZJRS 4XSZA 2JA7C 4BY7C 3GTQC 3GTOC 4A3GC 1QRTA 4JXXA 4G7ZA 3GTJC 5GAGW 2A68A 4BXXC 1ZJWA
chains in the Genus database with same CATH topology
5BNZA 4WCES 1QRUA 4IO9S 3X1LB 1UDXA 5DM6S 1O0BA 5IZNA 4WFNS 1QTQA 3J7ZV 1EXDA 1GTSA 1FEUA 4H3SA 5GAEW 2RE8A 3PIOS 5HL7S 2ZJQS 1D6KA 3PIPS 3DLLS 1NYLA 4JYZA 3W2VB 3AIIA 5GADW 2ZJPS 4H4KA 1O0CA 1EUQA 5GAHW 4UY88 2RD2A 4WF9S 4IOCS 1B75A 4IOAS 4U67S 4WFBS 2ZJRS 5JVHS 1QRSA 1GTRA 5JVGS 1EUYA 5DM7S 4P2BA 3CF5S 4V194 2HZ7A 1DFUP 4WFAS 1QRTA 4JXXA 5GAGW 4JXZA 3W2WB 1ZJWA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5BNZ A;  4WCE S;  1QRU A;  4IO9 S;  5DM6 S;  1O0B A;  5IZN A;  4WFN S;  1QTQ A;  3J7Z V;  1EXD A;  1GTS A;  1FEU A;  4H3S A;  5GAE W;  2RE8 A;  3PIO S;  5HL7 S;  2ZJQ S;  1D6K A;  3PIP S;  3DLL S;  1NYL A;  4JYZ A;  3AII A;  5GAD W;  2ZJP S;  1O0C A;  1EUQ A;  5GAH W;  4UY8 8;  2RD2 A;  4WF9 S;  4IOC S;  1B75 A;  4IOA S;  4U67 S;  4WFB S;  2ZJR S;  5JVH S;  1QRS A;  1GTR A;  5JVG S;  1EUY A;  5DM7 S;  4P2B A;  3CF5 S;  1DFU P;  2HZ7 A;  4WFA S;  1QRT A;  4JXX A;  5GAG W;  4JXZ A;  1ZJW A; 
#chains in the Genus database with same CATH topology
 1TWG C;  4ZH4 A;  1IW7 A;  1QRU A;  5C4J C;  2O5I A;  2CX8 A;  4OIP A;  5C4X C;  3RZD C;  2E2J C;  3LYW A;  4Q5S A;  1EXD A;  1GTS A;  5IYB C;  2KPU A;  2RE8 A;  2B63 C;  3PIO S;  5HL7 S;  3S1Q C;  2A6E A;  3DLL S;  1I50 C;  3CZB A;  4MEX A;  3S1M C;  1O0C A;  1EUQ A;  1TWC C;  1YNN A;  2KQ1 A;  5GAH W;  4UY8 8;  4L69 A;  4IOC S;  4XLP A;  5C44 C;  4A3J C;  4A3I C;  3S14 C;  4BBS C;  4YG2 A;  1NXZ A;  4LK0 A;  2YU9 C;  3RZO C;  2O5J A;  3S2D C;  1QRS A;  2PJJ A;  2Y0S D;  2R92 C;  4J3C A;  4JK1 A;  4XSX A;  1K83 C;  5C3E C;  4P2B A;  1I6H C;  1Z85 A;  4G7H A;  1ZYR A;  4OIO A;  2WB1 D;  1VHK A;  4QIW D;  3GTM C;  5HQH A;  3GTL C;  1YNJ A;  1WCM C;  4YFN A;  1Y1V C;  2CW0 A;  5BNZ A;  3X1L B;  2NVY C;  3M4O C;  1O0B A;  1HQM A;  2BE5 A;  5TMC A;  2WAQ D;  1FEU A;  3K7A C;  4H3S A;  4BY1 C;  4XLN A;  1D6K A;  4MQ9 A;  3PIP S;  1NYL A;  3H3V D;  4A3C C;  4KN7 A;  3HOY C;  4OIN A;  3M3Y C;  2VUM C;  2G6G A;  4A3B C;  4LJZ A;  5IYD C;  2RD2 A;  1I6V A;  4WF9 S;  2JA6 C;  2PNW A;  3DXJ A;  4X6A C;  4C3H C;  3KW2 A;  4U67 S;  4LK1 A;  5JVG S;  4AYB D;  3CQZ C;  1EUY A;  5DM7 S;  4V19 4;  1DFU P;  2AE0 X;  2HZ7 A;  4A3L C;  3HOW C;  2EGW A;  4WFA S;  3S1N C;  1V6Z A;  3GTK C;  1R9T C;  4JXZ A;  3W2W B;  3I4N C;  4YFX A;  2R7Z C;  3HOV C;  5TMF A;  2GAE A;  2PI8 A;  4IO9 S;  5DM6 S;  3EQL A;  5IZN A;  4YFK A;  2EGV A;  3HOX C;  4A3M C;  3S15 C;  1SMY A;  5GAE W;  4C3I C;  1TWF C;  3S17 C;  1Y1W C;  2L3U A;  4JYZ A;  3W2V B;  3AII A;  3S2H C;  2ZJP S;  2NVX C;  4C3J C;  4H4K A;  1VHY A;  4BBR C;  4A3F C;  3S1R C;  4KN4 A;  4E8B A;  1B75 A;  2JA8 C;  2NVT C;  4WFB S;  5JVH S;  1BDF A;  4GZY A;  3HOU C;  1GTR A;  5IYC C;  2E2I C;  2E2H C;  3HOZ C;  4OIR A;  3CF5 S;  3GTP C;  3HKZ D;  2A6H A;  4QJV A;  4NOI A;  2R93 C;  2G5D A;  4MEY A;  2PPB A;  1TWA C;  4Q4Z A;  4LLG A;  4WCE S;  1UDX A;  1TWH C;  4C2M C;  4A3E C;  4OIQ A;  4A3K C;  3I4M C;  3PO2 C;  4WFN S;  1QTQ A;  2NVQ C;  3J7Z V;  2JA5 C;  3PO3 C;  2NWA A;  2ZJQ S;  2A69 A;  1I3Q C;  2KXY A;  2PIC A;  3H0G C;  5D4D A;  3WOD A;  1SFO C;  3S16 C;  2PA8 D;  3GTG C;  4A3D C;  4G7O A;  2Z0Y A;  5GAD W;  2PMZ D;  5IP7 C;  4A93 C;  2L5N A;  5IP9 C;  4Y52 C;  5FLM C;  4KMU A;  4Y7N C;  3FKI C;  4IOA S;  2ZJR S;  4XSZ A;  2JA7 C;  4BY7 C;  3GTQ C;  3GTO C;  4A3G C;  1QRT A;  4JXX A;  4G7Z A;  3GTJ C;  5GAG W;  2A68 A;  4BXX C;  1ZJW A; 
#chains in the Genus database with same CATH homology
 5BNZ A;  4WCE S;  1QRU A;  4IO9 S;  3X1L B;  1UDX A;  5DM6 S;  1O0B A;  5IZN A;  4WFN S;  1QTQ A;  3J7Z V;  1EXD A;  1GTS A;  1FEU A;  4H3S A;  5GAE W;  2RE8 A;  3PIO S;  5HL7 S;  2ZJQ S;  1D6K A;  3PIP S;  3DLL S;  1NYL A;  4JYZ A;  3W2V B;  3AII A;  5GAD W;  2ZJP S;  4H4K A;  1O0C A;  1EUQ A;  5GAH W;  4UY8 8;  2RD2 A;  4WF9 S;  4IOC S;  1B75 A;  4IOA S;  4U67 S;  4WFB S;  2ZJR S;  5JVH S;  1QRS A;  1GTR A;  5JVG S;  1EUY A;  5DM7 S;  4P2B A;  3CF5 S;  4V19 4;  2HZ7 A;  1DFU P;  4WFA S;  1QRT A;  4JXX A;  5GAG W;  4JXZ A;  3W2W B;  1ZJW A; 
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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