4WLSA

Crystal structure of the metal-free (repressor) form of e. coli cuer, a copper efflux regulator, bound to copa promoter dna
Total Genus 43
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
111
structure length
111
Chain Sequence
MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHLNELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMRDQLLALANA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Allosteric transcriptional regulation via changes in the overall topology of the core promoter.
pubmed doi rcsb
molecule tags Transcription regulator/dna
source organism Escherichia coli dh5[alpha]
molecule keywords HTH-type transcriptional regulator CueR
total genus 43
structure length 111
sequence length 111
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-10-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00376 MerR MerR family regulatory protein
A PF09278 MerR-DNA-bind MerR, DNA binding
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1660.10 Mainly Alpha Orthogonal Bundle Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 Multidrug-efflux Transporter Regulator; Chain: A; Domain 2 4wlsA00
1JBGA 2DG6A 3D6ZA 3GP4A 1Q06A 4R4EA 1Q0AA 2VZ4A 3Q5RA 1EXIA 4WLWA 3HH0A 3Q3DA 3D70A 3Q1MA 1Q09A 3UCSA 5I44A 3Q5SA 1EXJA 4R22B 3GPVA 1R8EA 5I41B 4J2NA 3Q2YA 2JMLA 1Q05A 3Q5PA 5E01A 5D8CA 4R24B 3D6YA 2ZHGA 3D71A 2ZHHA 1R8DA 4WLSA 1Q07A 3QAOA 3IAOA 1Q08A 5D90A
chains in the Genus database with same CATH superfamily
1JBGA 2DG6A 1LX8A 3D6ZA 3GP4A 1Q06A 3EZ6A 4R4EA 1Q0AA 1PM6A 2VZ4A 3Q5RA 1EXIA 4WLWA 3HH0A 4LHFA 3Q3DA 3D70A 4DCZA 3Q1MA 1Q09A 3UCSA 5I44A 3Q5SA 1EXJA 2IEFA 3EZFA 4R22B 2OG0A 2KVVA 3GPVA 1R8EA 5I41B 1Y6UA 4J2NA 3Q2YA 2JMLA 3EZ9A 1Q05A 3Q5PA 5E01A 5D8CA 3EZ2A 4R24B 3D6YA 2ZHGA 1RH6A 3D71A 2ZHHA 3EZ7A 1R8DA 4WLSA 1Q07A 3QAOA 3IAOA 1Q08A 5D90A
chains in the Genus database with same CATH topology
1JBGA 2DG6A 1LX8A 3D6ZA 3GP4A 1Q06A 3EZ6A 4R4EA 1Q0AA 1PM6A 2VZ4A 3Q5RA 1EXIA 4WLWA 3HH0A 4LHFA 3Q3DA 3D70A 4DCZA 3Q1MA 1Q09A 3UCSA 5I44A 3Q5SA 1EXJA 2IEFA 3EZFA 4R22B 2OG0A 2KVVA 3GPVA 1R8EA 5I41B 1Y6UA 4J2NA 3Q2YA 2JMLA 3EZ9A 1Q05A 3Q5PA 5E01A 5D8CA 3EZ2A 4R24B 3D6YA 2ZHGA 1RH6A 3D71A 2ZHHA 3EZ7A 1R8DA 4WLSA 1Q07A 3QAOA 3IAOA 1Q08A 5D90A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JBG A;  2DG6 A;  3D6Z A;  3GP4 A;  1Q06 A;  4R4E A;  1Q0A A;  2VZ4 A;  3Q5R A;  1EXI A;  4WLW A;  3HH0 A;  3Q3D A;  3D70 A;  3Q1M A;  1Q09 A;  3UCS A;  5I44 A;  3Q5S A;  1EXJ A;  4R22 B;  3GPV A;  1R8E A;  5I41 B;  4J2N A;  3Q2Y A;  2JML A;  1Q05 A;  3Q5P A;  5E01 A;  5D8C A;  4R24 B;  3D6Y A;  2ZHG A;  3D71 A;  2ZHH A;  1R8D A;  4WLS A;  1Q07 A;  3QAO A;  3IAO A;  1Q08 A;  5D90 A; 
#chains in the Genus database with same CATH topology
 1JBG A;  2DG6 A;  1LX8 A;  3D6Z A;  3GP4 A;  1Q06 A;  3EZ6 A;  4R4E A;  1Q0A A;  1PM6 A;  2VZ4 A;  3Q5R A;  1EXI A;  4WLW A;  3HH0 A;  4LHF A;  3Q3D A;  3D70 A;  4DCZ A;  3Q1M A;  1Q09 A;  3UCS A;  5I44 A;  3Q5S A;  1EXJ A;  2IEF A;  3EZF A;  4R22 B;  2OG0 A;  2KVV A;  3GPV A;  1R8E A;  5I41 B;  1Y6U A;  4J2N A;  3Q2Y A;  2JML A;  3EZ9 A;  1Q05 A;  3Q5P A;  5E01 A;  5D8C A;  3EZ2 A;  4R24 B;  3D6Y A;  2ZHG A;  1RH6 A;  3D71 A;  2ZHH A;  3EZ7 A;  1R8D A;  4WLS A;  1Q07 A;  3QAO A;  3IAO A;  1Q08 A;  5D90 A; 
#chains in the Genus database with same CATH homology
 1JBG A;  2DG6 A;  1LX8 A;  3D6Z A;  3GP4 A;  1Q06 A;  3EZ6 A;  4R4E A;  1Q0A A;  1PM6 A;  2VZ4 A;  3Q5R A;  1EXI A;  4WLW A;  3HH0 A;  4LHF A;  3Q3D A;  3D70 A;  4DCZ A;  3Q1M A;  1Q09 A;  3UCS A;  5I44 A;  3Q5S A;  1EXJ A;  2IEF A;  3EZF A;  4R22 B;  2OG0 A;  2KVV A;  3GPV A;  1R8E A;  5I41 B;  1Y6U A;  4J2N A;  3Q2Y A;  2JML A;  3EZ9 A;  1Q05 A;  3Q5P A;  5E01 A;  5D8C A;  3EZ2 A;  4R24 B;  3D6Y A;  2ZHG A;  1RH6 A;  3D71 A;  2ZHH A;  3EZ7 A;  1R8D A;  4WLS A;  1Q07 A;  3QAO A;  3IAO A;  1Q08 A;  5D90 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...