4WPCA

Crystal structure of rgd1p f-bar domain in complex with inositol phosphate
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
297
structure length
283
Chain Sequence
FSTPEIKKVLNSDVAINALLSRLKQSLLTCEEFMKFIRKKYAFEEEHVQELSKQYKHFFNIQNSSLKKMIHEVLGFDGKMAQVKQSYITALQKMYSEISSLLLTMTKLRKSVKENSKRLEKDVSDAIHSAEKAQSRYNSLCQDWDKLRKTKLTLRGSKTTKEQEEELLRKIDNADLEYKQKVDHSNSLRNTFITKERPRIVQELKDLILEIDTAMTIQLQKYTIWTENLVLNTGVTISPLDSTKSMKSFAGSVSNERDLYSFLNKYNQLINKNLIPVSYKKHP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Comparison of Saccharomyces cerevisiae F-BAR Domain Structures Reveals a Conserved Inositol Phosphate Binding Site.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Lipid binding protein
molecule keywords RHO GTPase-activating protein RGD1
total genus 112
structure length 283
sequence length 297
chains with identical sequence B
ec nomenclature
pdb deposition date 2014-10-17
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1270.60 Mainly Alpha Up-down Bundle Substrate Binding Domain Of Dnak; Chain:A; Domain 2 Arfaptin homology (AH) domain/BAR domain 4wpcA00
3I2WA 1I4LA 2RAKA 2X3XA 2YKTA 1X03A 4FZSA 2Z0OA 3PLTA 4DCNC 2Z0VA 2EFLA 2X3WA 5C5BB 1URUA 2C08A 3HAJA 2EFKA 2Q12A 2X3VA 3QWEA 4NQIA 3Q0KA 4I1QA 3M3WA 2D4CA 2Z0NA 3QNIA 4WPEA 2RAIA 3SOGA 1I4TA 1WDZA 4NSWA 3LLLA 4DYLA 1ZWWA 4H8SA 2D1LA 2V0OA 3HAHA 3DYTA 1I49A 3HAIA 3ABHA 2ELBA 1X04A 4AKVA 3CAZA 1Y2OA 4AVMA 2Q13A 2RAJA 4BNEA 3QE6A 3G9GA 3SYVA 4ATMA 5C5BA 3Q84A 4WPCA 2FICA 1I4DA 3ACOA 3OK8A
chains in the Genus database with same CATH superfamily
2PY6A 3D52A 3I39X 3I04A 3DX2A 2RAKA 3BVVA 4JWCA 4AZ5A 3T46A 2WINM 2YLAA 4IWPA 3DPOA 3T49A 2X3WA 4HR1B 5C5BB 4EZTA 1QX1A 1URUA 3DX3A 2C08A 2RT6A 2EFKA 2YIAA 2ALWA 2LM0A 3Q0KA 4I1QA 2YL8A 3D2EA 3M3WA 2D4CA 2Z0NA 4UDYX 4EZZA 3F7WA 1E2UA 1HTYA 2PMRA 3LVTA 1ZYLA 1LQ7A 3O3OB 5KBPA 1QWNA 4IWOA 4EZPA 3B51X 4UDXX 4DCNC 1ZWWA 2D1LA 5FLEX 1TQTA 2JNKA 1GNTA 3DYTA 4JWEA 4G6QA 2ELBA 3EJPA 3RV0A 4AKVA 1SU8A 2QKWA 3G9GA 1O7DB 3SYVA 4H6HA 2OW7A 3FD9A 4FZPA 1I4DA 4JL9A 2OBMA 1E1DA 4IWQA 2MI7A 3OK8A 3B52X 2GF4A 1I4LA 2YKTA 2X3XA 3EJQA 4FM3A 1X03A 3B53X 4FZSA 1TQWA 3LMFA 4AZGA 1TQVA 3BUPA 1DKYA 4IM0A 3CV5A 3HAJA 4R5JA 3VKHA 2OBLA 2X5CA 3T48A 1OA1A 4EZRA 4NPHA 3T4AG 2YIVX 4EZVA 1SUFA 3SOGA 4F00A 3BUQA 3DX1A 1DKXA 3LLLA 4H8SA 3D4ZA 2V0OA 3OWGA 1QWUA 3HAHA 4E3CA 3EJUA 4F01A 1OA0A 3ABHA 2GAFD 1X04A 2Z8YA 4JWIA 3D2FA 4EZWA 1GNLA 2RAJA 1R33A 3I01A 1W9MA 3QE6A 3BVUA 3C7NA 4HR1A 4ATMA 3Q84A 2NCZA 4B9QA 5C5BA 2FICA 4EZUA 3EJSA 3EJRA 4EZQA 4PO2A 1TQSA 3ACOA 4IW0A 1HWWA 4HYBA 3BUDA 2KHOA 3BVXA 1DKZA 2ND1A 2Z0OA 5TKYA 2EFLA 1YWMA 2F7RA 3D51A 2YI8A 4AZHA 2YI9A 4FZOA 3QWEA 4NQIA 2X3VA 4R5KA 2WYHA 1O7DC 4R5IA 4AZCB 2F18A 3QNIA 4WPEA 3QA8A 4JN4A 2RAIA 3EJTA 1PS3A 3CVRA 4JLCA 1SU6A 2OZNB 1WDZA 2O0I1 3DX0A 4NSWA 4KIKA 4DYLA 3GI7A 2EWFA 4HY9A 2ZXQA 2JNSA 4M0MA 1I49A 3HAIA 4JNFA 4D8JA 4AZCA 4R5GA 1R34A 3O3NB 1JQKA 2Q13A 3ZEDA 4AVMA 3KAVA 4EZXA 3RPMA 4EZOA 2WYIA 2YL9A 3KAWA 3BVTA 2F7QA 2QXLA 3D50A 3L3OM 4E81A 3I2WA 1SU7A 1U00A 3CZNA 3DX4A 4EZYA 1R5EA 3VEAA 1E9VA 3PLTA 1GN9A 2QFFA 4KIKB 2Z0VA 2YIBA 2F7PA 3BUIA 3DPQA 3DDGA 3O3MB 5FIGA 3D4YA 4AZ6A 3BVWA 2Q12A 4H6IA 3BLBA 2F7OA 1OAOA 1TQUA 3BUBA 3QNJA 2YL5A 4AZIA 4JWDA 1I4TA 2OO2A 2F1AA 2OW6A 2FYVA 4AZ7A 5E84A 3A98A 3CKDA 3DPPA 4JNEA 3UITA 2F1BA 3L3PA 4AZBA 2N3KA 1MJGA 4R5LA 3ERCC 3CAZA 1Y2OA 4EZNA 3RV1A 3CZSA 2GA9D 2YLLA 3KDRA 4BNEA 2YL6A 3ER8C 2ND0A 2LXYA 1HXKA 4EZSA 3DDFA 2EX3B 3OHXM 4IM2A 4IM3A 4WPCA 3T47A 3ER9B 1UPXA 3VEBA
chains in the Genus database with same CATH topology
3I2WA 1I4LA 2RAKA 2X3XA 2YKTA 1X03A 4FZSA 2Z0OA 3PLTA 4DCNC 2Z0VA 2EFLA 2X3WA 5C5BB 1URUA 2C08A 3HAJA 2EFKA 2Q12A 2X3VA 3QWEA 4NQIA 3Q0KA 4I1QA 3M3WA 2D4CA 2Z0NA 3QNIA 4WPEA 2RAIA 3SOGA 1I4TA 1WDZA 4NSWA 3LLLA 4DYLA 1ZWWA 4H8SA 2D1LA 2V0OA 3HAHA 3DYTA 1I49A 3HAIA 3ABHA 2ELBA 1X04A 4AKVA 3CAZA 1Y2OA 4AVMA 2Q13A 2RAJA 4BNEA 3QE6A 3G9GA 3SYVA 4ATMA 5C5BA 3Q84A 4WPCA 2FICA 1I4DA 3ACOA 3OK8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3I2W A;  1I4L A;  2RAK A;  2X3X A;  2YKT A;  1X03 A;  4FZS A;  2Z0O A;  3PLT A;  4DCN C;  2Z0V A;  2EFL A;  2X3W A;  5C5B B;  1URU A;  2C08 A;  3HAJ A;  2EFK A;  2Q12 A;  2X3V A;  3QWE A;  4NQI A;  3Q0K A;  4I1Q A;  3M3W A;  2D4C A;  2Z0N A;  3QNI A;  4WPE A;  2RAI A;  3SOG A;  1I4T A;  1WDZ A;  4NSW A;  3LLL A;  4DYL A;  1ZWW A;  4H8S A;  2D1L A;  2V0O A;  3HAH A;  3DYT A;  1I49 A;  3HAI A;  3ABH A;  2ELB A;  1X04 A;  4AKV A;  3CAZ A;  1Y2O A;  4AVM A;  2Q13 A;  2RAJ A;  4BNE A;  3QE6 A;  3G9G A;  3SYV A;  4ATM A;  5C5B A;  3Q84 A;  4WPC A;  2FIC A;  1I4D A;  3ACO A;  3OK8 A; 
#chains in the Genus database with same CATH topology
 2PY6 A;  3D52 A;  3I39 X;  3I04 A;  3DX2 A;  2RAK A;  3BVV A;  4JWC A;  4AZ5 A;  3T46 A;  2WIN M;  2YLA A;  4IWP A;  3DPO A;  3T49 A;  2X3W A;  4HR1 B;  5C5B B;  4EZT A;  1QX1 A;  1URU A;  3DX3 A;  2C08 A;  2RT6 A;  2EFK A;  2YIA A;  2ALW A;  2LM0 A;  3Q0K A;  4I1Q A;  2YL8 A;  3D2E A;  3M3W A;  2D4C A;  2Z0N A;  4UDY X;  4EZZ A;  3F7W A;  1E2U A;  1HTY A;  2PMR A;  3LVT A;  1ZYL A;  1LQ7 A;  3O3O B;  5KBP A;  1QWN A;  4IWO A;  4EZP A;  3B51 X;  4UDX X;  4DCN C;  1ZWW A;  2D1L A;  5FLE X;  1TQT A;  2JNK A;  1GNT A;  3DYT A;  4JWE A;  4G6Q A;  2ELB A;  3EJP A;  3RV0 A;  4AKV A;  1SU8 A;  2QKW A;  3G9G A;  1O7D B;  3SYV A;  4H6H A;  2OW7 A;  3FD9 A;  4FZP A;  1I4D A;  4JL9 A;  2OBM A;  1E1D A;  4IWQ A;  2MI7 A;  3OK8 A;  3B52 X;  2GF4 A;  1I4L A;  2YKT A;  2X3X A;  3EJQ A;  4FM3 A;  1X03 A;  3B53 X;  4FZS A;  1TQW A;  3LMF A;  4AZG A;  1TQV A;  3BUP A;  1DKY A;  4IM0 A;  3CV5 A;  3HAJ A;  4R5J A;  3VKH A;  2OBL A;  2X5C A;  3T48 A;  1OA1 A;  4EZR A;  4NPH A;  3T4A G;  2YIV X;  4EZV A;  1SUF A;  3SOG A;  4F00 A;  3BUQ A;  3DX1 A;  1DKX A;  3LLL A;  4H8S A;  3D4Z A;  2V0O A;  3OWG A;  1QWU A;  3HAH A;  4E3C A;  3EJU A;  4F01 A;  1OA0 A;  3ABH A;  2GAF D;  1X04 A;  2Z8Y A;  4JWI A;  3D2F A;  4EZW A;  1GNL A;  2RAJ A;  1R33 A;  3I01 A;  1W9M A;  3QE6 A;  3BVU A;  3C7N A;  4HR1 A;  4ATM A;  3Q84 A;  2NCZ A;  4B9Q A;  5C5B A;  2FIC A;  4EZU A;  3EJS A;  3EJR A;  4EZQ A;  4PO2 A;  1TQS A;  3ACO A;  4IW0 A;  1HWW A;  4HYB A;  3BUD A;  2KHO A;  3BVX A;  1DKZ A;  2ND1 A;  2Z0O A;  5TKY A;  2EFL A;  1YWM A;  2F7R A;  3D51 A;  2YI8 A;  4AZH A;  2YI9 A;  4FZO A;  3QWE A;  4NQI A;  2X3V A;  4R5K A;  2WYH A;  1O7D C;  4R5I A;  4AZC B;  2F18 A;  3QNI A;  4WPE A;  3QA8 A;  4JN4 A;  2RAI A;  3EJT A;  1PS3 A;  3CVR A;  4JLC A;  1SU6 A;  2OZN B;  1WDZ A;  2O0I 1;  3DX0 A;  4NSW A;  4KIK A;  4DYL A;  3GI7 A;  2EWF A;  4HY9 A;  2ZXQ A;  2JNS A;  4M0M A;  1I49 A;  3HAI A;  4JNF A;  4D8J A;  4AZC A;  4R5G A;  1R34 A;  3O3N B;  1JQK A;  2Q13 A;  3ZED A;  4AVM A;  3KAV A;  4EZX A;  3RPM A;  4EZO A;  2WYI A;  2YL9 A;  3KAW A;  3BVT A;  2F7Q A;  2QXL A;  3D50 A;  3L3O M;  4E81 A;  3I2W A;  1SU7 A;  1U00 A;  3CZN A;  3DX4 A;  4EZY A;  1R5E A;  3VEA A;  1E9V A;  3PLT A;  1GN9 A;  2QFF A;  4KIK B;  2Z0V A;  2YIB A;  2F7P A;  3BUI A;  3DPQ A;  3DDG A;  3O3M B;  5FIG A;  3D4Y A;  4AZ6 A;  3BVW A;  2Q12 A;  4H6I A;  3BLB A;  2F7O A;  1OAO A;  1TQU A;  3BUB A;  3QNJ A;  2YL5 A;  4AZI A;  4JWD A;  1I4T A;  2OO2 A;  2F1A A;  2OW6 A;  2FYV A;  4AZ7 A;  5E84 A;  3A98 A;  3CKD A;  3DPP A;  4JNE A;  3UIT A;  2F1B A;  3L3P A;  4AZB A;  2N3K A;  1MJG A;  4R5L A;  3ERC C;  3CAZ A;  1Y2O A;  4EZN A;  3RV1 A;  3CZS A;  2GA9 D;  2YLL A;  3KDR A;  4BNE A;  2YL6 A;  3ER8 C;  2ND0 A;  2LXY A;  1HXK A;  4EZS A;  3DDF A;  2EX3 B;  3OHX M;  4IM2 A;  4IM3 A;  4WPC A;  3T47 A;  3ER9 B;  1UPX A;  3VEB A; 
#chains in the Genus database with same CATH homology
 3I2W A;  1I4L A;  2RAK A;  2X3X A;  2YKT A;  1X03 A;  4FZS A;  2Z0O A;  3PLT A;  4DCN C;  2Z0V A;  2EFL A;  2X3W A;  5C5B B;  1URU A;  2C08 A;  3HAJ A;  2EFK A;  2Q12 A;  2X3V A;  3QWE A;  4NQI A;  3Q0K A;  4I1Q A;  3M3W A;  2D4C A;  2Z0N A;  3QNI A;  4WPE A;  2RAI A;  3SOG A;  1I4T A;  1WDZ A;  4NSW A;  3LLL A;  4DYL A;  1ZWW A;  4H8S A;  2D1L A;  2V0O A;  3HAH A;  3DYT A;  1I49 A;  3HAI A;  3ABH A;  2ELB A;  1X04 A;  4AKV A;  3CAZ A;  1Y2O A;  4AVM A;  2Q13 A;  2RAJ A;  4BNE A;  3QE6 A;  3G9G A;  3SYV A;  4ATM A;  5C5B A;  3Q84 A;  4WPC A;  2FIC A;  1I4D A;  3ACO A;  3OK8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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