4WQOD

Structure of vhl-elob-eloc-cul2
Total Genus 52
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
52
sequence length
159
structure length
141
Chain Sequence
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNPLMEIGELALDMWRKLMVEPLQAIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transcription
molecule keywords Von Hippel-Lindau disease tumor suppressor
publication title Insights into Cullin-RING E3 Ubiquitin Ligase Recruitment: Structure of the VHL-EloBC-Cul2 Complex.
pubmed doi rcsb
source organism Homo sapiens
total genus 52
structure length 141
sequence length 159
ec nomenclature
pdb deposition date 2014-10-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1310.10 Mainly Alpha Up-down Bundle 5 helical Cullin repeat like Cullin Repeats 4wqoD00
3DPLC 4HXIB 4JGHD 4A64A 1LDKB 4WQOD 1LDKA 2WZKA 3RTRA 4APFB 4F52A 4P5OA 4EOZB 4N9F3 1U6GA 1LDJA 3DQVC 4AP2B
chains in the Genus database with same CATH superfamily
4JGHD 1LDKB 4WQOD 4F52A 4N9F3 1LDJA 4A64A 2PFVA 3CMLA 4NUUA 4APFB 2WZKA 2Y8DA 5F3JA 4P5OA 4NUVA 3BQIA 4AP2B 3DQVC 3RRCA 1LDKA 2B1EA 3BQLA 4EOZB 2XU0A 3BQKA 3DPLC 4HXIB 4YFSA 3RTRA 2WAUA 3CPZA 1U6GA
chains in the Genus database with same CATH topology
3DPLC 4HXIB 4JGHD 4A64A 1LDKB 4WQOD 1LDKA 2WZKA 3RTRA 4APFB 4F52A 4P5OA 4EOZB 4N9F3 1U6GA 1LDJA 3DQVC 4AP2B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3DPL C;  4HXI B;  4JGH D;  4A64 A;  1LDK B;  4WQO D;  1LDK A;  2WZK A;  3RTR A;  4APF B;  4F52 A;  4P5O A;  4EOZ B;  4N9F 3;  1U6G A;  1LDJ A;  3DQV C;  4AP2 B; 
#chains in the Genus database with same CATH topology
 4JGH D;  1LDK B;  4WQO D;  4F52 A;  4N9F 3;  1LDJ A;  4A64 A;  2PFV A;  3CML A;  4NUU A;  4APF B;  2WZK A;  2Y8D A;  5F3J A;  4P5O A;  4NUV A;  3BQI A;  4AP2 B;  3DQV C;  3RRC A;  1LDK A;  2B1E A;  3BQL A;  4EOZ B;  2XU0 A;  3BQK A;  3DPL C;  4HXI B;  4YFS A;  3RTR A;  2WAU A;  3CPZ A;  1U6G A; 
#chains in the Genus database with same CATH homology
 3DPL C;  4HXI B;  4JGH D;  4A64 A;  1LDK B;  4WQO D;  1LDK A;  2WZK A;  3RTR A;  4APF B;  4F52 A;  4P5O A;  4EOZ B;  4N9F 3;  1U6G A;  1LDJ A;  3DQV C;  4AP2 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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