4WZ8B

Crystal structure of human-yeast chimera acetyl coa carboxylase ct domain bound to compound 6
Total Genus 221
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
221
sequence length
710
structure length
698
Chain Sequence
LRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGASALNKVLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQQAGQVWFPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPEGTVEIKFRREKLLDTMNRLDDKYRELRSQLSNKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Ligase/ligase inhibitor
molecule keywords Acetyl-CoA carboxylase
total genus 221
structure length 698
sequence length 710
chains with identical sequence C
ec nomenclature ec 6.3.4.14: Biotin carboxylase.
pdb deposition date 2014-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01039 Carboxyl_trans Carboxyl transferase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.460.10 Mainly Beta Beta Barrel ClpP/crotonase fold Biotin dependent carboxylase carboxyltransferase 4wz8B02
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 4wz8B01
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 4wz8B03
3MFMA 5E0NX 2X24A 1SG4A 4MI2A 4MXIA 1EY3A 3Q7HA 1TYFA 4EMPA 2FW2A 5FUSA 4JWVA 4U0GA 1ON3A 3P85A 2DEOA 3GMAA 4IZDA 4ZDCA 3PE8A 2VSSE 4JCRA 2J5GD 3OC7A 4FJWD 3V5EA 4ELSA 2ZQQA 3LKEA 4JOTA 3M6NA 4QFEA 4EMMA 2F6QA 1PIXA 4DI1A 3LAOA 3QWDA 4YLHA 1WDKA 4GM2A 3OMEA 3H0SA 2PBPA 4HC8A 1UYSA 4QIIA 3STAA 2UZFA 4ZDEA 3U9SB 2ZL2A 3MYBA 4FNBA 4ZDFA 4B3HA 2EJ5A 3QK8A 3H02A 5DZKH 5IKLB 4B3IA 1Y7OA 4F47A 1ON9A 1YG8A 5G1RA 3BEZA 5KJPA 1EF9A 4U19A 3KQFA 3N6RB 3NJBA 3WG5A 1XNVA 3PGQA 4GHNA 1Q51A 2PPYA 4L6WA 3T8BA 2J5II 3QXZA 2F9IB 4LK5A 1K32A 2C8TA 2NP9A 3R9TA 2Q34A 3KTIA 4JJTA 3FDUA 4NEKA 4ASIA 4ZDDA 1XO6A 5E0SA 3R9QA 2ZQRA 4MOUA 3U9RB 3V5IA 5INIA 3RRVA 2FBMA 2VREA 1XNWA 3I47A 1O8UA 4ZU2A 1PJHA 5DTPA 2F9YB 4ELXA 1VRGA 3OT6A 2CE3A 3Q1TA 3TZ3A 5DUCA 3HE2A 3RSIA 3P5MA 3HINA 3T88A 3TV5A 3MOYA 4JYLA 4ZDBA 3GF7A 3QKAA 4K3WA 1FC6A 3KTHA 5DU8A 1RJMA 1XNYA 4JCSA 3QXIA 5FIFA 3T89A 4Q1IA 3U9TB 3IBBA 1JXZA 2HW5A 3GF3A 1W2XA 4KPKA 1XX4A 3RSTA 5DL1A 3VIVA 3ISAA 1NZYB 2WTBA 3ST9A 4QIJA 3M6MA 3ZWAA 1SZOA 2A7KA 3Q0GA 2F6IA 2J5GA 4I4ZA 2VSUF 1DCIA 3R6HA 3SLLA 4FZWA 4RCNA 4FN7A 4U18A 3TRRA 3BF0A 3DORA 4Z0MA 1FCFA 4U0GH 3K50A 1WZ8A 1UYRA 2A81A 4FN8A 5DTWA 3H0JA 4EMLA 1X0UA 4OG1A 4RYFA 3TT6A 2J5IB 2QQ3A 2DUBA 2D3TA 4I52A 2X58A 4JCQA 3FF6A 3ZW8A 4IZBA 4WYOB 5INGA 2VSUA 2BZRA 4G2RA 5CTCA 1OD2A 1NZYA 3TDCA 5KDRB 4RYFH 2A7SA 3KTGA 1Q52A 3SWXA 5CTBA 4IZCA 4WCZA 1N6DA 3R9SA 3BPPA 4JYJA 3Q0JA 3TT7A 1FC9A 2Q2XA 1UYTA 2ZL4A 1UYVA 2W3PA 4KD6A 3H0QA 4JSBA 1OD4A 1EF8A 4WZ8B 1UIYA 3QYRA 4U0HA 3MT6A 1N6FA 1J7XA 1MJ3A 1HNUA 2VX2A 4L8KA 5JBXA 2J5IA 3HP0A 2VSUE 4KNPA 5C9GA 1DUBA 4FZWC 5DZKA 1FC7A 3KTJA 1YG6A 2FZSA 4K29A 3HLN1 3QREA 5MGBA 3H81A 3TVUA 4NNQA 3ZW9A 2PG8A 1WDLA 2VSSF 4KWBA 3KTKA 2VSUC 3HRXA 3IB9A 1N6EA 5G1QA 2J5SA 3GKBA 2VSSA 5DKPA 5C90A 2F9YA 4JCTA 5E0SH 5INFA 5KDRA 1K39A 2ZL3A 3PZKA 4JFCA 3R0OA 4JVTA 1HNOA 2ZL0A 4FB8A 2CBYA 4Q0GA 3L3SA 5JBWA 2IEXA 3QMJA 1TG6A 1HZDA 4HNKA 5DUFA 4FNDA 1RJNA 5DU4A 4OMRA 5G1SA 1WDMA 4K2NA 2F9IA 4B3JA 3G64A 2Q35A 3NJDA 3GLMA 2GTRA 4I42A 4U1AA 3TVWA 4OLQA 3TLFA 4ELWA 3K8XA 3IAVA 5DU6A 3H0UA 3T3WA 3JU1A 3ZWCA 3ZWBA 3PEAA 3P2LA 3T8AA 3DJAA
chains in the Genus database with same CATH superfamily
3MFMA 5E0NX 2X24A 1SG4A 4MI2A 4MXIA 1EY3A 3Q7HA 1TYFA 4EMPA 2FW2A 5FUSA 4JWVA 4U0GA 1ON3A 3P85A 2DEOA 3GMAA 4IZDA 4ZDCA 3PE8A 2VSSE 4JCRA 2J5GD 3OC7A 3BPTA 4FJWD 3V5EA 4ELSA 2ZQQA 3LKEA 4JOTA 3M6NA 4QFEA 4EMMA 2F6QA 1PIXA 4DI1A 3LAOA 3QWDA 4YLHA 1WDKA 4GM2A 3OMEA 3H0SA 2PBPA 4HC8A 1UYSA 4QIIA 3STAA 2UZFA 2YJGA 4ZDEA 3U9SB 2ZL2A 3MYBA 4FNBA 4ZDFA 4B3HA 2EJ5A 3QK8A 3H02A 5DZKH 5IKLB 4B3IA 1Y7OA 4F47A 1ON9A 1YG8A 5G1RA 3BEZA 5KJPA 1EF9A 4U19A 3KQFA 3N6RB 3NJBA 3WG5A 1XNVA 3PGQA 4GHNA 1Q51A 2PPYA 4L6WA 3T8BA 2J5II 4NARA 3QXZA 2F9IB 4LK5A 1K32A 2C8TA 2NP9A 3R9TA 2Q34A 3KTIA 4JJTA 3FDUA 4NEKA 4ASIA 4HDTA 4ZDDA 1XO6A 5E0SA 3R9QA 2ZQRA 4MOUA 3U9RB 3V5IA 5INIA 3RRVA 2FBMA 2VREA 1XNWA 3I47A 1O8UA 4ZU2A 1PJHA 5DTPA 2F9YB 4ELXA 1VRGA 3OT6A 2CE3A 3Q1TA 3TZ3A 5DUCA 3HE2A 3RSIA 3P5MA 4J2UA 3HINA 3T88A 3TV5A 3MOYA 4JYLA 4ZDBA 3GF7A 3QKAA 4K3WA 1FC6A 3KTHA 5DU8A 1RJMA 1XNYA 4JCSA 3QXIA 5FIFA 3T89A 4Q1IA 3U9TB 3IBBA 1JXZA 2HW5A 3GF3A 1W2XA 4KPKA 1XX4A 3RSTA 5DL1A 3VIVA 3ISAA 1NZYB 2WTBA 3ST9A 4QIJA 3M6MA 3ZWAA 1SZOA 2A7KA 3Q0GA 2F6IA 2J5GA 4I4ZA 2VSUF 1DCIA 3R6HA 3SLLA 4FZWA 4RCNA 4FN7A 4U18A 3TRRA 3BF0A 3DORA 4Z0MA 1FCFA 4U0GH 3K50A 1WZ8A 1UYRA 2A81A 4FN8A 5DTWA 3H0JA 4EMLA 1X0UA 4OG1A 4RYFA 5HUQA 3TT6A 2J5IB 2QQ3A 2DUBA 2D3TA 4I52A 2X58A 4JCQA 3FF6A 3ZW8A 4IZBA 4WYOB 5INGA 2VSUA 2BZRA 4G2RA 5CTCA 1OD2A 1NZYA 3TDCA 5KDRB 4RYFH 2A7SA 3KTGA 1Q52A 3SWXA 5CTBA 4IZCA 4WCZA 1N6DA 3R9SA 3BPPA 4JYJA 3Q0JA 3TT7A 1FC9A 2Q2XA 1UYTA 2ZL4A 1UYVA 2W3PA 4KD6A 3H0QA 4JSBA 1OD4A 1EF8A 4WZ8B 1UIYA 3QYRA 4U0HA 3MT6A 1N6FA 1J7XA 1MJ3A 1HNUA 2VX2A 4L8KA 5JBXA 2J5IA 3HP0A 2VSUE 4KNPA 5C9GA 1DUBA 4FZWC 5DZKA 1FC7A 3KTJA 1YG6A 2FZSA 4K29A 3HLN1 3QREA 5MGBA 3H81A 3TVUA 4NNQA 3ZW9A 2PG8A 1WDLA 2VSSF 4KWBA 3KTKA 2VSUC 3HRXA 3IB9A 1N6EA 5G1QA 2J5SA 3GKBA 2VSSA 5DKPA 5C90A 2F9YA 4JCTA 5E0SH 5INFA 5KDRA 1K39A 2ZL3A 3PZKA 4JFCA 3R0OA 4JVTA 1HNOA 2ZL0A 4FB8A 2CBYA 4Q0GA 3L3SA 5JBWA 2IEXA 3QMJA 1TG6A 1HZDA 4HNKA 5DUFA 4FNDA 1RJNA 5DU4A 4OMRA 5G1SA 1WDMA 4K2NA 2F9IA 4B3JA 3G64A 2Q35A 3NJDA 3GLMA 2GTRA 4I42A 4U1AA 3TVWA 4OLQA 3TLFA 4ELWA 3K8XA 3IAVA 5DU6A 3H0UA 3T3WA 3JU1A 3ZWCA 3ZWBA 3PEAA 3P2LA 3T8AA 3DJAA
chains in the Genus database with same CATH topology
3MFMA 5E0NX 2X24A 1SG4A 4MI2A 4MXIA 1EY3A 3Q7HA 1TYFA 4EMPA 2FW2A 5FUSA 4JWVA 4U0GA 1ON3A 3P85A 2DEOA 3GMAA 4IZDA 4ZDCA 3PE8A 2VSSE 4JCRA 2J5GD 3OC7A 3BPTA 4FJWD 3V5EA 4ELSA 2ZQQA 3LKEA 4JOTA 3M6NA 4QFEA 4EMMA 2F6QA 1PIXA 4DI1A 3LAOA 3QWDA 4YLHA 1WDKA 4GM2A 3OMEA 3H0SA 2PBPA 4HC8A 1UYSA 4QIIA 3STAA 2UZFA 2YJGA 4ZDEA 3U9SB 2ZL2A 3MYBA 4FNBA 4ZDFA 4B3HA 2EJ5A 3QK8A 3H02A 5DZKH 5IKLB 4B3IA 1Y7OA 4F47A 1ON9A 1YG8A 5G1RA 3BEZA 5KJPA 1EF9A 4U19A 3KQFA 3N6RB 3NJBA 3WG5A 1XNVA 3PGQA 4GHNA 1Q51A 2PPYA 4L6WA 3T8BA 2J5II 4NARA 3QXZA 2F9IB 4LK5A 1K32A 2C8TA 2NP9A 3R9TA 2Q34A 3KTIA 4JJTA 3FDUA 4NEKA 4ASIA 4HDTA 4ZDDA 1XO6A 5E0SA 3R9QA 2ZQRA 4MOUA 3U9RB 3V5IA 5INIA 3RRVA 2FBMA 2VREA 1XNWA 3I47A 1O8UA 4ZU2A 1PJHA 5DTPA 2F9YB 4ELXA 1VRGA 3OT6A 2CE3A 3Q1TA 3TZ3A 5DUCA 3HE2A 3RSIA 3P5MA 4J2UA 3HINA 3T88A 3TV5A 3MOYA 4JYLA 4ZDBA 3GF7A 3QKAA 4K3WA 1FC6A 3KTHA 5DU8A 1RJMA 1XNYA 4JCSA 3QXIA 5FIFA 3T89A 4Q1IA 3U9TB 3IBBA 1JXZA 2HW5A 3GF3A 1W2XA 4KPKA 1XX4A 3RSTA 5DL1A 3VIVA 3ISAA 1NZYB 2WTBA 3ST9A 4QIJA 3M6MA 3ZWAA 1SZOA 2A7KA 3Q0GA 2F6IA 2J5GA 4I4ZA 2VSUF 1DCIA 3R6HA 3SLLA 4FZWA 4RCNA 4FN7A 4U18A 3TRRA 3BF0A 3DORA 4Z0MA 1FCFA 4U0GH 3K50A 1WZ8A 1UYRA 2A81A 4FN8A 5DTWA 3H0JA 4EMLA 1X0UA 4OG1A 4RYFA 5HUQA 3TT6A 2J5IB 2QQ3A 2DUBA 2D3TA 4I52A 2X58A 4JCQA 3FF6A 3ZW8A 4IZBA 4WYOB 5INGA 2VSUA 2BZRA 4G2RA 5CTCA 1OD2A 1NZYA 3TDCA 5KDRB 4RYFH 2A7SA 3KTGA 1Q52A 3SWXA 5CTBA 4IZCA 4WCZA 1N6DA 3R9SA 3BPPA 4JYJA 3Q0JA 3TT7A 1FC9A 2Q2XA 1UYTA 2ZL4A 1UYVA 2W3PA 4KD6A 3H0QA 4JSBA 1OD4A 1EF8A 4WZ8B 1UIYA 3QYRA 4U0HA 3MT6A 1N6FA 1J7XA 1MJ3A 1HNUA 2VX2A 4L8KA 5JBXA 2J5IA 3HP0A 2VSUE 4KNPA 5C9GA 1DUBA 4FZWC 5DZKA 1FC7A 3KTJA 1YG6A 2FZSA 4K29A 3HLN1 3QREA 5MGBA 3H81A 3TVUA 4NNQA 3ZW9A 2PG8A 1WDLA 2VSSF 4KWBA 3KTKA 2VSUC 3HRXA 3IB9A 1N6EA 5G1QA 2J5SA 3GKBA 2VSSA 5DKPA 5C90A 2F9YA 4JCTA 5E0SH 5INFA 5KDRA 1K39A 2ZL3A 3PZKA 4JFCA 3R0OA 4JVTA 1HNOA 2ZL0A 4FB8A 2CBYA 4Q0GA 3L3SA 5JBWA 2IEXA 3QMJA 1TG6A 1HZDA 4HNKA 5DUFA 4FNDA 1RJNA 5DU4A 4OMRA 5G1SA 1WDMA 4K2NA 2F9IA 4B3JA 3G64A 2Q35A 3NJDA 3GLMA 2GTRA 4I42A 4U1AA 3TVWA 4OLQA 3TLFA 4ELWA 3K8XA 3IAVA 5DU6A 3H0UA 3T3WA 3JU1A 3ZWCA 3ZWBA 3PEAA 3P2LA 3T8AA 3DJAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MFM A;  5E0N X;  2X24 A;  1SG4 A;  4MI2 A;  4MXI A;  1EY3 A;  3Q7H A;  1TYF A;  4EMP A;  2FW2 A;  5FUS A;  4JWV A;  4U0G A;  1ON3 A;  3P85 A;  2DEO A;  3GMA A;  4IZD A;  4ZDC A;  3PE8 A;  2VSS E;  4JCR A;  2J5G D;  3OC7 A;  4FJW D;  3V5E A;  4ELS A;  2ZQQ A;  3LKE A;  4JOT A;  3M6N A;  4QFE A;  4EMM A;  2F6Q A;  1PIX A;  4DI1 A;  3LAO A;  3QWD A;  4YLH A;  1WDK A;  4GM2 A;  3OME A;  3H0S A;  2PBP A;  4HC8 A;  1UYS A;  4QII A;  3STA A;  2UZF A;  4ZDE A;  3U9S B;  2ZL2 A;  3MYB A;  4FNB A;  4ZDF A;  4B3H A;  2EJ5 A;  3QK8 A;  3H02 A;  5DZK H;  5IKL B;  4B3I A;  1Y7O A;  4F47 A;  1ON9 A;  1YG8 A;  5G1R A;  3BEZ A;  5KJP A;  1EF9 A;  4U19 A;  3KQF A;  3N6R B;  3NJB A;  3WG5 A;  1XNV A;  3PGQ A;  4GHN A;  1Q51 A;  2PPY A;  4L6W A;  3T8B A;  2J5I I;  3QXZ A;  2F9I B;  4LK5 A;  1K32 A;  2C8T A;  2NP9 A;  3R9T A;  2Q34 A;  3KTI A;  4JJT A;  3FDU A;  4NEK A;  4ASI A;  4ZDD A;  1XO6 A;  5E0S A;  3R9Q A;  2ZQR A;  4MOU A;  3U9R B;  3V5I A;  5INI A;  3RRV A;  2FBM A;  2VRE A;  1XNW A;  3I47 A;  1O8U A;  4ZU2 A;  1PJH A;  5DTP A;  2F9Y B;  4ELX A;  1VRG A;  3OT6 A;  2CE3 A;  3Q1T A;  3TZ3 A;  5DUC A;  3HE2 A;  3RSI A;  3P5M A;  3HIN A;  3T88 A;  3TV5 A;  3MOY A;  4JYL A;  4ZDB A;  3GF7 A;  3QKA A;  4K3W A;  1FC6 A;  3KTH A;  5DU8 A;  1RJM A;  1XNY A;  4JCS A;  3QXI A;  5FIF A;  3T89 A;  4Q1I A;  3U9T B;  3IBB A;  1JXZ A;  2HW5 A;  3GF3 A;  1W2X A;  4KPK A;  1XX4 A;  3RST A;  5DL1 A;  3VIV A;  3ISA A;  1NZY B;  2WTB A;  3ST9 A;  4QIJ A;  3M6M A;  3ZWA A;  1SZO A;  2A7K A;  3Q0G A;  2F6I A;  2J5G A;  4I4Z A;  2VSU F;  1DCI A;  3R6H A;  3SLL A;  4FZW A;  4RCN A;  4FN7 A;  4U18 A;  3TRR A;  3BF0 A;  3DOR A;  4Z0M A;  1FCF A;  4U0G H;  3K50 A;  1WZ8 A;  1UYR A;  2A81 A;  4FN8 A;  5DTW A;  3H0J A;  4EML A;  1X0U A;  4OG1 A;  4RYF A;  3TT6 A;  2J5I B;  2QQ3 A;  2DUB A;  2D3T A;  4I52 A;  2X58 A;  4JCQ A;  3FF6 A;  3ZW8 A;  4IZB A;  4WYO B;  5ING A;  2VSU A;  2BZR A;  4G2R A;  5CTC A;  1OD2 A;  1NZY A;  3TDC A;  5KDR B;  4RYF H;  2A7S A;  3KTG A;  1Q52 A;  3SWX A;  5CTB A;  4IZC A;  4WCZ A;  1N6D A;  3R9S A;  3BPP A;  4JYJ A;  3Q0J A;  3TT7 A;  1FC9 A;  2Q2X A;  1UYT A;  2ZL4 A;  1UYV A;  2W3P A;  4KD6 A;  3H0Q A;  4JSB A;  1OD4 A;  1EF8 A;  4WZ8 B;  1UIY A;  3QYR A;  4U0H A;  3MT6 A;  1N6F A;  1J7X A;  1MJ3 A;  1HNU A;  2VX2 A;  4L8K A;  5JBX A;  2J5I A;  3HP0 A;  2VSU E;  4KNP A;  5C9G A;  1DUB A;  4FZW C;  5DZK A;  1FC7 A;  3KTJ A;  1YG6 A;  2FZS A;  4K29 A;  3HLN 1;  3QRE A;  5MGB A;  3H81 A;  3TVU A;  4NNQ A;  3ZW9 A;  2PG8 A;  1WDL A;  2VSS F;  4KWB A;  3KTK A;  2VSU C;  3HRX A;  3IB9 A;  1N6E A;  5G1Q A;  2J5S A;  3GKB A;  2VSS A;  5DKP A;  5C90 A;  2F9Y A;  4JCT A;  5E0S H;  5INF A;  5KDR A;  1K39 A;  2ZL3 A;  3PZK A;  4JFC A;  3R0O A;  4JVT A;  1HNO A;  2ZL0 A;  4FB8 A;  2CBY A;  4Q0G A;  3L3S A;  5JBW A;  2IEX A;  3QMJ A;  1TG6 A;  1HZD A;  4HNK A;  5DUF A;  4FND A;  1RJN A;  5DU4 A;  4OMR A;  5G1S A;  1WDM A;  4K2N A;  2F9I A;  4B3J A;  3G64 A;  2Q35 A;  3NJD A;  3GLM A;  2GTR A;  4I42 A;  4U1A A;  3TVW A;  4OLQ A;  3TLF A;  4ELW A;  3K8X A;  3IAV A;  5DU6 A;  3H0U A;  3T3W A;  3JU1 A;  3ZWC A;  3ZWB A;  3PEA A;  3P2L A;  3T8A A;  3DJA A; 
#chains in the Genus database with same CATH topology
 3MFM A;  5E0N X;  2X24 A;  1SG4 A;  4MI2 A;  4MXI A;  1EY3 A;  3Q7H A;  1TYF A;  4EMP A;  2FW2 A;  5FUS A;  4JWV A;  4U0G A;  1ON3 A;  3P85 A;  2DEO A;  3GMA A;  4IZD A;  4ZDC A;  3PE8 A;  2VSS E;  4JCR A;  2J5G D;  3OC7 A;  3BPT A;  4FJW D;  3V5E A;  4ELS A;  2ZQQ A;  3LKE A;  4JOT A;  3M6N A;  4QFE A;  4EMM A;  2F6Q A;  1PIX A;  4DI1 A;  3LAO A;  3QWD A;  4YLH A;  1WDK A;  4GM2 A;  3OME A;  3H0S A;  2PBP A;  4HC8 A;  1UYS A;  4QII A;  3STA A;  2UZF A;  2YJG A;  4ZDE A;  3U9S B;  2ZL2 A;  3MYB A;  4FNB A;  4ZDF A;  4B3H A;  2EJ5 A;  3QK8 A;  3H02 A;  5DZK H;  5IKL B;  4B3I A;  1Y7O A;  4F47 A;  1ON9 A;  1YG8 A;  5G1R A;  3BEZ A;  5KJP A;  1EF9 A;  4U19 A;  3KQF A;  3N6R B;  3NJB A;  3WG5 A;  1XNV A;  3PGQ A;  4GHN A;  1Q51 A;  2PPY A;  4L6W A;  3T8B A;  2J5I I;  4NAR A;  3QXZ A;  2F9I B;  4LK5 A;  1K32 A;  2C8T A;  2NP9 A;  3R9T A;  2Q34 A;  3KTI A;  4JJT A;  3FDU A;  4NEK A;  4ASI A;  4HDT A;  4ZDD A;  1XO6 A;  5E0S A;  3R9Q A;  2ZQR A;  4MOU A;  3U9R B;  3V5I A;  5INI A;  3RRV A;  2FBM A;  2VRE A;  1XNW A;  3I47 A;  1O8U A;  4ZU2 A;  1PJH A;  5DTP A;  2F9Y B;  4ELX A;  1VRG A;  3OT6 A;  2CE3 A;  3Q1T A;  3TZ3 A;  5DUC A;  3HE2 A;  3RSI A;  3P5M A;  4J2U A;  3HIN A;  3T88 A;  3TV5 A;  3MOY A;  4JYL A;  4ZDB A;  3GF7 A;  3QKA A;  4K3W A;  1FC6 A;  3KTH A;  5DU8 A;  1RJM A;  1XNY A;  4JCS A;  3QXI A;  5FIF A;  3T89 A;  4Q1I A;  3U9T B;  3IBB A;  1JXZ A;  2HW5 A;  3GF3 A;  1W2X A;  4KPK A;  1XX4 A;  3RST A;  5DL1 A;  3VIV A;  3ISA A;  1NZY B;  2WTB A;  3ST9 A;  4QIJ A;  3M6M A;  3ZWA A;  1SZO A;  2A7K A;  3Q0G A;  2F6I A;  2J5G A;  4I4Z A;  2VSU F;  1DCI A;  3R6H A;  3SLL A;  4FZW A;  4RCN A;  4FN7 A;  4U18 A;  3TRR A;  3BF0 A;  3DOR A;  4Z0M A;  1FCF A;  4U0G H;  3K50 A;  1WZ8 A;  1UYR A;  2A81 A;  4FN8 A;  5DTW A;  3H0J A;  4EML A;  1X0U A;  4OG1 A;  4RYF A;  5HUQ A;  3TT6 A;  2J5I B;  2QQ3 A;  2DUB A;  2D3T A;  4I52 A;  2X58 A;  4JCQ A;  3FF6 A;  3ZW8 A;  4IZB A;  4WYO B;  5ING A;  2VSU A;  2BZR A;  4G2R A;  5CTC A;  1OD2 A;  1NZY A;  3TDC A;  5KDR B;  4RYF H;  2A7S A;  3KTG A;  1Q52 A;  3SWX A;  5CTB A;  4IZC A;  4WCZ A;  1N6D A;  3R9S A;  3BPP A;  4JYJ A;  3Q0J A;  3TT7 A;  1FC9 A;  2Q2X A;  1UYT A;  2ZL4 A;  1UYV A;  2W3P A;  4KD6 A;  3H0Q A;  4JSB A;  1OD4 A;  1EF8 A;  4WZ8 B;  1UIY A;  3QYR A;  4U0H A;  3MT6 A;  1N6F A;  1J7X A;  1MJ3 A;  1HNU A;  2VX2 A;  4L8K A;  5JBX A;  2J5I A;  3HP0 A;  2VSU E;  4KNP A;  5C9G A;  1DUB A;  4FZW C;  5DZK A;  1FC7 A;  3KTJ A;  1YG6 A;  2FZS A;  4K29 A;  3HLN 1;  3QRE A;  5MGB A;  3H81 A;  3TVU A;  4NNQ A;  3ZW9 A;  2PG8 A;  1WDL A;  2VSS F;  4KWB A;  3KTK A;  2VSU C;  3HRX A;  3IB9 A;  1N6E A;  5G1Q A;  2J5S A;  3GKB A;  2VSS A;  5DKP A;  5C90 A;  2F9Y A;  4JCT A;  5E0S H;  5INF A;  5KDR A;  1K39 A;  2ZL3 A;  3PZK A;  4JFC A;  3R0O A;  4JVT A;  1HNO A;  2ZL0 A;  4FB8 A;  2CBY A;  4Q0G A;  3L3S A;  5JBW A;  2IEX A;  3QMJ A;  1TG6 A;  1HZD A;  4HNK A;  5DUF A;  4FND A;  1RJN A;  5DU4 A;  4OMR A;  5G1S A;  1WDM A;  4K2N A;  2F9I A;  4B3J A;  3G64 A;  2Q35 A;  3NJD A;  3GLM A;  2GTR A;  4I42 A;  4U1A A;  3TVW A;  4OLQ A;  3TLF A;  4ELW A;  3K8X A;  3IAV A;  5DU6 A;  3H0U A;  3T3W A;  3JU1 A;  3ZWC A;  3ZWB A;  3PEA A;  3P2L A;  3T8A A;  3DJA A; 
#chains in the Genus database with same CATH homology
 3MFM A;  5E0N X;  2X24 A;  1SG4 A;  4MI2 A;  4MXI A;  1EY3 A;  3Q7H A;  1TYF A;  4EMP A;  2FW2 A;  5FUS A;  4JWV A;  4U0G A;  1ON3 A;  3P85 A;  2DEO A;  3GMA A;  4IZD A;  4ZDC A;  3PE8 A;  2VSS E;  4JCR A;  2J5G D;  3OC7 A;  3BPT A;  4FJW D;  3V5E A;  4ELS A;  2ZQQ A;  3LKE A;  4JOT A;  3M6N A;  4QFE A;  4EMM A;  2F6Q A;  1PIX A;  4DI1 A;  3LAO A;  3QWD A;  4YLH A;  1WDK A;  4GM2 A;  3OME A;  3H0S A;  2PBP A;  4HC8 A;  1UYS A;  4QII A;  3STA A;  2UZF A;  2YJG A;  4ZDE A;  3U9S B;  2ZL2 A;  3MYB A;  4FNB A;  4ZDF A;  4B3H A;  2EJ5 A;  3QK8 A;  3H02 A;  5DZK H;  5IKL B;  4B3I A;  1Y7O A;  4F47 A;  1ON9 A;  1YG8 A;  5G1R A;  3BEZ A;  5KJP A;  1EF9 A;  4U19 A;  3KQF A;  3N6R B;  3NJB A;  3WG5 A;  1XNV A;  3PGQ A;  4GHN A;  1Q51 A;  2PPY A;  4L6W A;  3T8B A;  2J5I I;  4NAR A;  3QXZ A;  2F9I B;  4LK5 A;  1K32 A;  2C8T A;  2NP9 A;  3R9T A;  2Q34 A;  3KTI A;  4JJT A;  3FDU A;  4NEK A;  4ASI A;  4HDT A;  4ZDD A;  1XO6 A;  5E0S A;  3R9Q A;  2ZQR A;  4MOU A;  3U9R B;  3V5I A;  5INI A;  3RRV A;  2FBM A;  2VRE A;  1XNW A;  3I47 A;  1O8U A;  4ZU2 A;  1PJH A;  5DTP A;  2F9Y B;  4ELX A;  1VRG A;  3OT6 A;  2CE3 A;  3Q1T A;  3TZ3 A;  5DUC A;  3HE2 A;  3RSI A;  3P5M A;  4J2U A;  3HIN A;  3T88 A;  3TV5 A;  3MOY A;  4JYL A;  4ZDB A;  3GF7 A;  3QKA A;  4K3W A;  1FC6 A;  3KTH A;  5DU8 A;  1RJM A;  1XNY A;  4JCS A;  3QXI A;  5FIF A;  3T89 A;  4Q1I A;  3U9T B;  3IBB A;  1JXZ A;  2HW5 A;  3GF3 A;  1W2X A;  4KPK A;  1XX4 A;  3RST A;  5DL1 A;  3VIV A;  3ISA A;  1NZY B;  2WTB A;  3ST9 A;  4QIJ A;  3M6M A;  3ZWA A;  1SZO A;  2A7K A;  3Q0G A;  2F6I A;  2J5G A;  4I4Z A;  2VSU F;  1DCI A;  3R6H A;  3SLL A;  4FZW A;  4RCN A;  4FN7 A;  4U18 A;  3TRR A;  3BF0 A;  3DOR A;  4Z0M A;  1FCF A;  4U0G H;  3K50 A;  1WZ8 A;  1UYR A;  2A81 A;  4FN8 A;  5DTW A;  3H0J A;  4EML A;  1X0U A;  4OG1 A;  4RYF A;  5HUQ A;  3TT6 A;  2J5I B;  2QQ3 A;  2DUB A;  2D3T A;  4I52 A;  2X58 A;  4JCQ A;  3FF6 A;  3ZW8 A;  4IZB A;  4WYO B;  5ING A;  2VSU A;  2BZR A;  4G2R A;  5CTC A;  1OD2 A;  1NZY A;  3TDC A;  5KDR B;  4RYF H;  2A7S A;  3KTG A;  1Q52 A;  3SWX A;  5CTB A;  4IZC A;  4WCZ A;  1N6D A;  3R9S A;  3BPP A;  4JYJ A;  3Q0J A;  3TT7 A;  1FC9 A;  2Q2X A;  1UYT A;  2ZL4 A;  1UYV A;  2W3P A;  4KD6 A;  3H0Q A;  4JSB A;  1OD4 A;  1EF8 A;  4WZ8 B;  1UIY A;  3QYR A;  4U0H A;  3MT6 A;  1N6F A;  1J7X A;  1MJ3 A;  1HNU A;  2VX2 A;  4L8K A;  5JBX A;  2J5I A;  3HP0 A;  2VSU E;  4KNP A;  5C9G A;  1DUB A;  4FZW C;  5DZK A;  1FC7 A;  3KTJ A;  1YG6 A;  2FZS A;  4K29 A;  3HLN 1;  3QRE A;  5MGB A;  3H81 A;  3TVU A;  4NNQ A;  3ZW9 A;  2PG8 A;  1WDL A;  2VSS F;  4KWB A;  3KTK A;  2VSU C;  3HRX A;  3IB9 A;  1N6E A;  5G1Q A;  2J5S A;  3GKB A;  2VSS A;  5DKP A;  5C90 A;  2F9Y A;  4JCT A;  5E0S H;  5INF A;  5KDR A;  1K39 A;  2ZL3 A;  3PZK A;  4JFC A;  3R0O A;  4JVT A;  1HNO A;  2ZL0 A;  4FB8 A;  2CBY A;  4Q0G A;  3L3S A;  5JBW A;  2IEX A;  3QMJ A;  1TG6 A;  1HZD A;  4HNK A;  5DUF A;  4FND A;  1RJN A;  5DU4 A;  4OMR A;  5G1S A;  1WDM A;  4K2N A;  2F9I A;  4B3J A;  3G64 A;  2Q35 A;  3NJD A;  3GLM A;  2GTR A;  4I42 A;  4U1A A;  3TVW A;  4OLQ A;  3TLF A;  4ELW A;  3K8X A;  3IAV A;  5DU6 A;  3H0U A;  3T3W A;  3JU1 A;  3ZWC A;  3ZWB A;  3PEA A;  3P2L A;  3T8A A;  3DJA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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