4WZ8B

Crystal structure of human-yeast chimera acetyl coa carboxylase ct domain bound to compound 6
Total Genus 221
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
221
sequence length
710
structure length
698
Chain Sequence
LRPIATPYPVKEWLQPKRYKAHLMGTTYVYDFPELFRQASSSQWKNFSADVKLTDDFFISNELIEDENGELTEVEREPGANAIGMVAFKITVKTPEYPRGRQFVVVANDITFKIGSFGPQEDEFFNKVTEYARKRGIPRIYLAANSGARIGMAEEIVPLFQVAWNDAANPDKGFQYLYLTSEGMETLKKFDKENSVLTERTVINGEERFVIKTIIGSEDGLGVECLRGSGLIAGATSRAYHDIFTITLVTCRSVGIGAYLVRLGQRAIQVEGQPIILTGASALNKVLGREVYTSNLQLGGTQIMYNNGVSHLTAVDDLAGVEKIVEWMSYVPAKRNMPVPILETKDTWDRPVDFTPTNDETYDVRWMIEGRETESGFEYGLFDKGSFFETLSGWAKGVVVGRARLGGIPLGVIGVETRTVENLIPADPANPNSAETLIQQAGQVWFPNSAFKTAQAINDFNNGEQLPMMILANWRGFSGGQRDMFNEVLKYGSFIVDALVDYKQPIIIYIPPTGELRGGSWVVVDPTINADQMEMYADVNARAGVLEPEGTVEIKFRREKLLDTMNRLDDKYRELRSQLSNKQLADRERELLPIYGQISLQFADLHDRSSRMVAKGVISKELEWTEARRFFFWRLRRRLNEEYLIKRLSHQVGEASRLEKIARIRSWYPASVDHEDDRQVATWIEENYKTLDDKLKGL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes.
pubmed doi rcsb
source organism Saccharomyces cerevisiae
molecule tags Ligase/ligase inhibitor
molecule keywords Acetyl-CoA carboxylase
total genus 221
structure length 698
sequence length 710
chains with identical sequence C
ec nomenclature ec 6.3.4.14: Biotin carboxylase.
pdb deposition date 2014-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF01039 Carboxyl_trans Carboxyl transferase domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.460.10 Mainly Beta Beta Barrel ClpP/crotonase fold Biotin dependent carboxylase carboxyltransferase 4wz8B02
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 4wz8B01
3.90.226.10 Alpha Beta Alpha-Beta Complex 2-enoyl-CoA Hydratase; Chain A, domain 1 2-enoyl-CoA Hydratase; Chain A, domain 1 4wz8B03
2J5II 2FBMA 3SWXA 4B3IA 2QQ3A 2F9YA 4L8KA 1K32A 3RSIA 3OC7A 1WDMA 5DU4A 3R9SA 3BF0A 3STAA 5DUFA 3P2LA 3V5EA 5DL1A 3ZWBA 5KDRB 3GKBA 3JU1A 4EMLA 4U0GH 4QFEA 2UZFA 3ZW8A 3OMEA 4HNKA 2A7SA 3PGQA 1DUBA 1HZDA 5CTCA 4OG1A 3KTIA 3HP0A 5DTWA 1DCIA 4FJWD 2D3TA 3R9TA 3IB9A 4L6WA 3QREA 1WDKA 1J7XA 2EJ5A 4U0GA 3H81A 5DKPA 4K3WA 4OLQA 1XNVA 2J5GA 1OD2A 3TT6A 2ZQRA 3DJAA 5IKLB 1W2XA 1YG8A 5E0NX 4JCRA 1SZOA 5E0SA 3KQFA 3IAVA 5DU8A 4MOUA 1Y7OA 2NP9A 1TYFA 2ZL0A 3GF7A 4KPKA 4K2NA 1Q51A 2Q2XA 4ZU2A 2DUBA 2WTBA 2A81A 1FCFA 3Q7HA 3V5IA 5INIA 4FB8A 3GF3A 5DUCA 3FDUA 3HE2A 3NJDA 4JVTA 3MT6A 4Q0GA 1HNOA 3DORA 4ELSA 3KTGA 2J5IB 3L3SA 3PE8A 3TDCA 3Q0GA 2ZQQA 4GHNA 2BZRA 2C8TA 4Q1IA 1UYRA 4I4ZA 4FZWA 2J5IA 3H0QA 4MI2A 2ZL2A 3TZ3A 2GTRA 5FIFA 3T8AA 3KTKA 1FC7A 1XNYA 3T8BA 2FW2A 4RYFA 5JBXA 2F6QA 3R0OA 4NNQA 2X58A 4MXIA 5G1SA 3HRXA 1XO6A 4JYJA 5C9GA 3ISAA 4ZDFA 3OT6A 4ZDDA 5DTPA 4I52A 3U9SB 3QK8A 3T88A 4RYFH 4JSBA 2J5GD 2CBYA 4ASIA 2VSSA 4KD6A 4OMRA 4NEKA 1UYTA 4ZDCA 5DU6A 3Q1TA 4ZDEA 4QIJA 4U18A 3QYRA 4IZCA 1WZ8A 2Q35A 5JBWA 4YLHA 1VRGA 1UYSA 3GMAA 4FN8A 3RSTA 3GLMA 3P85A 4B3JA 4JYLA 1RJNA 2PG8A 4B3HA 2DEOA 4FZWC 5INFA 3H02A 2X24A 4EMPA 1XNWA 4KWBA 1MJ3A 3TT7A 4LK5A 3LAOA 4JCQA 3KTJA 1FC6A 1FC9A 1NZYB 3RRVA 5DZKH 2A7KA 5E0SH 4QIIA 4G2RA 1PIXA 1N6FA 4HC8A 1XX4A 2VSUA 4FNDA 4EMMA 3R6HA 2VREA 3U9TB 3FF6A 3HLN1 1K39A 4GM2A 4JWVA 4ZDBA 3LKEA 2F6IA 3VIVA 2PPYA 1PJHA 3TVUA 3PZKA 2ZL4A 4K29A 4JJTA 5G1RA 1SG4A 2VSSE 3ZW9A 4U1AA 1HNUA 1WDLA 3TVWA 3BEZA 3H0JA 1JXZA 1UYVA 5G1QA 3BPPA 2W3PA 3ZWCA 4WYOB 4WCZA 3R9QA 2FZSA 2VX2A 3TRRA 4JFCA 1N6EA 4FNBA 5DZKA 5C90A 4F47A 3QWDA 1YG6A 1N6DA 3M6MA 3G64A 1TG6A 2VSUF 3T89A 1O8UA 5INGA 4U19A 3HINA 4JCSA 2F9IA 1UIYA 1EF8A 1OD4A 3MFMA 3H0SA 5MGBA 3K8XA 5KDRA 4Z0MA 3MOYA 1NZYA 2VSUC 3QMJA 2Q34A 2F9IB 3MYBA 4FN7A 3K50A 4WZ8B 2VSSF 1EY3A 3SLLA 3M6NA 5FUSA 2CE3A 3IBBA 3KTHA 2VSUE 3QXZA 3H0UA 1ON9A 3ST9A 1X0UA 3WG5A 1Q52A 3ZWAA 5CTBA 3NJBA 2ZL3A 4ELXA 3Q0JA 2PBPA 5KJPA 3QXIA 1EF9A 3PEAA 4KNPA 4DI1A 2HW5A 4IZBA 3U9RB 3N6RB 1ON3A 2IEXA 3T3WA 2J5SA 3I47A 4JCTA 3TLFA 4JOTA 3TV5A 4U0HA 1RJMA 3P5MA 4ELWA 2F9YB 3QKAA 4IZDA 4RCNA 4I42A
chains in the Genus database with same CATH superfamily
2J5II 2FBMA 3SWXA 4B3IA 2QQ3A 2F9YA 4L8KA 2YJGA 1K32A 3RSIA 3OC7A 1WDMA 5DU4A 3R9SA 3BF0A 3STAA 5DUFA 3P2LA 3V5EA 5DL1A 3ZWBA 5KDRB 3GKBA 3JU1A 4EMLA 4U0GH 4QFEA 2UZFA 3ZW8A 4NARA 3OMEA 4HNKA 2A7SA 3PGQA 1DUBA 1HZDA 5CTCA 4OG1A 3KTIA 3HP0A 5DTWA 1DCIA 4FJWD 2D3TA 3R9TA 3IB9A 4L6WA 3QREA 1WDKA 3BPTA 1J7XA 2EJ5A 4U0GA 3H81A 5DKPA 4K3WA 4OLQA 1XNVA 2J5GA 1OD2A 3TT6A 2ZQRA 3DJAA 5IKLB 1W2XA 1YG8A 5E0NX 4JCRA 1SZOA 5E0SA 3KQFA 3IAVA 5DU8A 4MOUA 1Y7OA 2NP9A 1TYFA 2ZL0A 3GF7A 4KPKA 4K2NA 1Q51A 2Q2XA 4ZU2A 2DUBA 2WTBA 2A81A 1FCFA 3Q7HA 3V5IA 5INIA 4FB8A 3GF3A 5DUCA 3FDUA 3HE2A 3NJDA 4JVTA 3MT6A 4Q0GA 1HNOA 3DORA 4ELSA 3KTGA 2J5IB 3L3SA 3PE8A 3TDCA 3Q0GA 2ZQQA 4GHNA 2BZRA 2C8TA 4Q1IA 1UYRA 4I4ZA 4FZWA 2J5IA 3H0QA 4MI2A 2ZL2A 3TZ3A 2GTRA 5FIFA 3T8AA 3KTKA 1FC7A 1XNYA 3T8BA 2FW2A 4RYFA 5JBXA 2F6QA 3R0OA 4NNQA 2X58A 4MXIA 5G1SA 3HRXA 1XO6A 4JYJA 5C9GA 3ISAA 4ZDFA 3OT6A 4ZDDA 5DTPA 4I52A 3U9SB 3QK8A 3T88A 4RYFH 4JSBA 2J5GD 2CBYA 4ASIA 2VSSA 4KD6A 4OMRA 4NEKA 1UYTA 4HDTA 5HUQA 4ZDCA 5DU6A 3Q1TA 4ZDEA 4QIJA 4U18A 3QYRA 4IZCA 1WZ8A 2Q35A 5JBWA 4YLHA 1VRGA 1UYSA 3GMAA 4FN8A 3RSTA 3GLMA 3P85A 4B3JA 4JYLA 1RJNA 2PG8A 4B3HA 4J2UA 2DEOA 4FZWC 5INFA 3H02A 2X24A 4EMPA 1XNWA 4KWBA 1MJ3A 3TT7A 4LK5A 3LAOA 4JCQA 3KTJA 1FC6A 1FC9A 1NZYB 3RRVA 5DZKH 2A7KA 5E0SH 4QIIA 4G2RA 1PIXA 1N6FA 4HC8A 1XX4A 2VSUA 4FNDA 4EMMA 3R6HA 2VREA 3U9TB 3FF6A 3HLN1 1K39A 4GM2A 4JWVA 4ZDBA 3LKEA 2F6IA 3VIVA 2PPYA 1PJHA 3TVUA 3PZKA 2ZL4A 4K29A 4JJTA 5G1RA 1SG4A 2VSSE 3ZW9A 4U1AA 1HNUA 1WDLA 3TVWA 3BEZA 3H0JA 1JXZA 1UYVA 5G1QA 3BPPA 2W3PA 3ZWCA 4WYOB 4WCZA 3R9QA 2FZSA 2VX2A 3TRRA 4JFCA 1N6EA 4FNBA 5DZKA 5C90A 4F47A 3QWDA 1YG6A 1N6DA 3M6MA 3G64A 1TG6A 2VSUF 3T89A 1O8UA 5INGA 4U19A 3HINA 4JCSA 2F9IA 1UIYA 1EF8A 1OD4A 3MFMA 3H0SA 5MGBA 3K8XA 5KDRA 4Z0MA 3MOYA 1NZYA 2VSUC 3QMJA 2Q34A 2F9IB 3MYBA 4FN7A 3K50A 4WZ8B 2VSSF 1EY3A 3SLLA 3M6NA 5FUSA 2CE3A 3IBBA 3KTHA 2VSUE 3QXZA 3H0UA 1ON9A 3ST9A 1X0UA 3WG5A 1Q52A 3ZWAA 5CTBA 3NJBA 2ZL3A 4ELXA 3Q0JA 2PBPA 5KJPA 3QXIA 1EF9A 3PEAA 4KNPA 4DI1A 2HW5A 4IZBA 3U9RB 3N6RB 1ON3A 2IEXA 3T3WA 2J5SA 3I47A 4JCTA 3TLFA 4JOTA 3TV5A 4U0HA 1RJMA 3P5MA 4ELWA 2F9YB 3QKAA 4IZDA 4RCNA 4I42A
chains in the Genus database with same CATH topology
2J5II 2FBMA 3SWXA 4B3IA 2QQ3A 2F9YA 4L8KA 2YJGA 1K32A 3RSIA 3OC7A 1WDMA 5DU4A 3R9SA 3BF0A 3STAA 5DUFA 3P2LA 3V5EA 5DL1A 3ZWBA 5KDRB 3GKBA 3JU1A 4EMLA 4U0GH 4QFEA 2UZFA 3ZW8A 4NARA 3OMEA 4HNKA 2A7SA 3PGQA 1DUBA 1HZDA 5CTCA 4OG1A 3KTIA 3HP0A 5DTWA 1DCIA 4FJWD 2D3TA 3R9TA 3IB9A 4L6WA 3QREA 1WDKA 3BPTA 1J7XA 2EJ5A 4U0GA 3H81A 5DKPA 4K3WA 4OLQA 1XNVA 2J5GA 1OD2A 3TT6A 2ZQRA 3DJAA 5IKLB 1W2XA 1YG8A 5E0NX 4JCRA 1SZOA 5E0SA 3KQFA 3IAVA 5DU8A 4MOUA 1Y7OA 2NP9A 1TYFA 2ZL0A 3GF7A 4KPKA 4K2NA 1Q51A 2Q2XA 4ZU2A 2DUBA 2WTBA 2A81A 1FCFA 3Q7HA 3V5IA 5INIA 4FB8A 3GF3A 5DUCA 3FDUA 3HE2A 3NJDA 4JVTA 3MT6A 4Q0GA 1HNOA 3DORA 4ELSA 3KTGA 2J5IB 3L3SA 3PE8A 3TDCA 3Q0GA 2ZQQA 4GHNA 2BZRA 2C8TA 4Q1IA 1UYRA 4I4ZA 4FZWA 2J5IA 3H0QA 4MI2A 2ZL2A 3TZ3A 2GTRA 5FIFA 3T8AA 3KTKA 1FC7A 1XNYA 3T8BA 2FW2A 4RYFA 5JBXA 2F6QA 3R0OA 4NNQA 2X58A 4MXIA 5G1SA 3HRXA 1XO6A 4JYJA 5C9GA 3ISAA 4ZDFA 3OT6A 4ZDDA 5DTPA 4I52A 3U9SB 3QK8A 3T88A 4RYFH 4JSBA 2J5GD 2CBYA 4ASIA 2VSSA 4KD6A 4OMRA 4NEKA 1UYTA 4HDTA 5HUQA 4ZDCA 5DU6A 3Q1TA 4ZDEA 4QIJA 4U18A 3QYRA 4IZCA 1WZ8A 2Q35A 5JBWA 4YLHA 1VRGA 1UYSA 3GMAA 4FN8A 3RSTA 3GLMA 3P85A 4B3JA 4JYLA 1RJNA 2PG8A 4B3HA 4J2UA 2DEOA 4FZWC 5INFA 3H02A 2X24A 4EMPA 1XNWA 4KWBA 1MJ3A 3TT7A 4LK5A 3LAOA 4JCQA 3KTJA 1FC6A 1FC9A 1NZYB 3RRVA 5DZKH 2A7KA 5E0SH 4QIIA 4G2RA 1PIXA 1N6FA 4HC8A 1XX4A 2VSUA 4FNDA 4EMMA 3R6HA 2VREA 3U9TB 3FF6A 3HLN1 1K39A 4GM2A 4JWVA 4ZDBA 3LKEA 2F6IA 3VIVA 2PPYA 1PJHA 3TVUA 3PZKA 2ZL4A 4K29A 4JJTA 5G1RA 1SG4A 2VSSE 3ZW9A 4U1AA 1HNUA 1WDLA 3TVWA 3BEZA 3H0JA 1JXZA 1UYVA 5G1QA 3BPPA 2W3PA 3ZWCA 4WYOB 4WCZA 3R9QA 2FZSA 2VX2A 3TRRA 4JFCA 1N6EA 4FNBA 5DZKA 5C90A 4F47A 3QWDA 1YG6A 1N6DA 3M6MA 3G64A 1TG6A 2VSUF 3T89A 1O8UA 5INGA 4U19A 3HINA 4JCSA 2F9IA 1UIYA 1EF8A 1OD4A 3MFMA 3H0SA 5MGBA 3K8XA 5KDRA 4Z0MA 3MOYA 1NZYA 2VSUC 3QMJA 2Q34A 2F9IB 3MYBA 4FN7A 3K50A 4WZ8B 2VSSF 1EY3A 3SLLA 3M6NA 5FUSA 2CE3A 3IBBA 3KTHA 2VSUE 3QXZA 3H0UA 1ON9A 3ST9A 1X0UA 3WG5A 1Q52A 3ZWAA 5CTBA 3NJBA 2ZL3A 4ELXA 3Q0JA 2PBPA 5KJPA 3QXIA 1EF9A 3PEAA 4KNPA 4DI1A 2HW5A 4IZBA 3U9RB 3N6RB 1ON3A 2IEXA 3T3WA 2J5SA 3I47A 4JCTA 3TLFA 4JOTA 3TV5A 4U0HA 1RJMA 3P5MA 4ELWA 2F9YB 3QKAA 4IZDA 4RCNA 4I42A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J5I I;  2FBM A;  3SWX A;  4B3I A;  2QQ3 A;  2F9Y A;  4L8K A;  1K32 A;  3RSI A;  3OC7 A;  1WDM A;  5DU4 A;  3R9S A;  3BF0 A;  3STA A;  5DUF A;  3P2L A;  3V5E A;  5DL1 A;  3ZWB A;  5KDR B;  3GKB A;  3JU1 A;  4EML A;  4U0G H;  4QFE A;  2UZF A;  3ZW8 A;  3OME A;  4HNK A;  2A7S A;  3PGQ A;  1DUB A;  1HZD A;  5CTC A;  4OG1 A;  3KTI A;  3HP0 A;  5DTW A;  1DCI A;  4FJW D;  2D3T A;  3R9T A;  3IB9 A;  4L6W A;  3QRE A;  1WDK A;  1J7X A;  2EJ5 A;  4U0G A;  3H81 A;  5DKP A;  4K3W A;  4OLQ A;  1XNV A;  2J5G A;  1OD2 A;  3TT6 A;  2ZQR A;  3DJA A;  5IKL B;  1W2X A;  1YG8 A;  5E0N X;  4JCR A;  1SZO A;  5E0S A;  3KQF A;  3IAV A;  5DU8 A;  4MOU A;  1Y7O A;  2NP9 A;  1TYF A;  2ZL0 A;  3GF7 A;  4KPK A;  4K2N A;  1Q51 A;  2Q2X A;  4ZU2 A;  2DUB A;  2WTB A;  2A81 A;  1FCF A;  3Q7H A;  3V5I A;  5INI A;  4FB8 A;  3GF3 A;  5DUC A;  3FDU A;  3HE2 A;  3NJD A;  4JVT A;  3MT6 A;  4Q0G A;  1HNO A;  3DOR A;  4ELS A;  3KTG A;  2J5I B;  3L3S A;  3PE8 A;  3TDC A;  3Q0G A;  2ZQQ A;  4GHN A;  2BZR A;  2C8T A;  4Q1I A;  1UYR A;  4I4Z A;  4FZW A;  2J5I A;  3H0Q A;  4MI2 A;  2ZL2 A;  3TZ3 A;  2GTR A;  5FIF A;  3T8A A;  3KTK A;  1FC7 A;  1XNY A;  3T8B A;  2FW2 A;  4RYF A;  5JBX A;  2F6Q A;  3R0O A;  4NNQ A;  2X58 A;  4MXI A;  5G1S A;  3HRX A;  1XO6 A;  4JYJ A;  5C9G A;  3ISA A;  4ZDF A;  3OT6 A;  4ZDD A;  5DTP A;  4I52 A;  3U9S B;  3QK8 A;  3T88 A;  4RYF H;  4JSB A;  2J5G D;  2CBY A;  4ASI A;  2VSS A;  4KD6 A;  4OMR A;  4NEK A;  1UYT A;  4ZDC A;  5DU6 A;  3Q1T A;  4ZDE A;  4QIJ A;  4U18 A;  3QYR A;  4IZC A;  1WZ8 A;  2Q35 A;  5JBW A;  4YLH A;  1VRG A;  1UYS A;  3GMA A;  4FN8 A;  3RST A;  3GLM A;  3P85 A;  4B3J A;  4JYL A;  1RJN A;  2PG8 A;  4B3H A;  2DEO A;  4FZW C;  5INF A;  3H02 A;  2X24 A;  4EMP A;  1XNW A;  4KWB A;  1MJ3 A;  3TT7 A;  4LK5 A;  3LAO A;  4JCQ A;  3KTJ A;  1FC6 A;  1FC9 A;  1NZY B;  3RRV A;  5DZK H;  2A7K A;  5E0S H;  4QII A;  4G2R A;  1PIX A;  1N6F A;  4HC8 A;  1XX4 A;  2VSU A;  4FND A;  4EMM A;  3R6H A;  2VRE A;  3U9T B;  3FF6 A;  3HLN 1;  1K39 A;  4GM2 A;  4JWV A;  4ZDB A;  3LKE A;  2F6I A;  3VIV A;  2PPY A;  1PJH A;  3TVU A;  3PZK A;  2ZL4 A;  4K29 A;  4JJT A;  5G1R A;  1SG4 A;  2VSS E;  3ZW9 A;  4U1A A;  1HNU A;  1WDL A;  3TVW A;  3BEZ A;  3H0J A;  1JXZ A;  1UYV A;  5G1Q A;  3BPP A;  2W3P A;  3ZWC A;  4WYO B;  4WCZ A;  3R9Q A;  2FZS A;  2VX2 A;  3TRR A;  4JFC A;  1N6E A;  4FNB A;  5DZK A;  5C90 A;  4F47 A;  3QWD A;  1YG6 A;  1N6D A;  3M6M A;  3G64 A;  1TG6 A;  2VSU F;  3T89 A;  1O8U A;  5ING A;  4U19 A;  3HIN A;  4JCS A;  2F9I A;  1UIY A;  1EF8 A;  1OD4 A;  3MFM A;  3H0S A;  5MGB A;  3K8X A;  5KDR A;  4Z0M A;  3MOY A;  1NZY A;  2VSU C;  3QMJ A;  2Q34 A;  2F9I B;  3MYB A;  4FN7 A;  3K50 A;  4WZ8 B;  2VSS F;  1EY3 A;  3SLL A;  3M6N A;  5FUS A;  2CE3 A;  3IBB A;  3KTH A;  2VSU E;  3QXZ A;  3H0U A;  1ON9 A;  3ST9 A;  1X0U A;  3WG5 A;  1Q52 A;  3ZWA A;  5CTB A;  3NJB A;  2ZL3 A;  4ELX A;  3Q0J A;  2PBP A;  5KJP A;  3QXI A;  1EF9 A;  3PEA A;  4KNP A;  4DI1 A;  2HW5 A;  4IZB A;  3U9R B;  3N6R B;  1ON3 A;  2IEX A;  3T3W A;  2J5S A;  3I47 A;  4JCT A;  3TLF A;  4JOT A;  3TV5 A;  4U0H A;  1RJM A;  3P5M A;  4ELW A;  2F9Y B;  3QKA A;  4IZD A;  4RCN A;  4I42 A; 
#chains in the Genus database with same CATH topology
 2J5I I;  2FBM A;  3SWX A;  4B3I A;  2QQ3 A;  2F9Y A;  4L8K A;  2YJG A;  1K32 A;  3RSI A;  3OC7 A;  1WDM A;  5DU4 A;  3R9S A;  3BF0 A;  3STA A;  5DUF A;  3P2L A;  3V5E A;  5DL1 A;  3ZWB A;  5KDR B;  3GKB A;  3JU1 A;  4EML A;  4U0G H;  4QFE A;  2UZF A;  3ZW8 A;  4NAR A;  3OME A;  4HNK A;  2A7S A;  3PGQ A;  1DUB A;  1HZD A;  5CTC A;  4OG1 A;  3KTI A;  3HP0 A;  5DTW A;  1DCI A;  4FJW D;  2D3T A;  3R9T A;  3IB9 A;  4L6W A;  3QRE A;  1WDK A;  3BPT A;  1J7X A;  2EJ5 A;  4U0G A;  3H81 A;  5DKP A;  4K3W A;  4OLQ A;  1XNV A;  2J5G A;  1OD2 A;  3TT6 A;  2ZQR A;  3DJA A;  5IKL B;  1W2X A;  1YG8 A;  5E0N X;  4JCR A;  1SZO A;  5E0S A;  3KQF A;  3IAV A;  5DU8 A;  4MOU A;  1Y7O A;  2NP9 A;  1TYF A;  2ZL0 A;  3GF7 A;  4KPK A;  4K2N A;  1Q51 A;  2Q2X A;  4ZU2 A;  2DUB A;  2WTB A;  2A81 A;  1FCF A;  3Q7H A;  3V5I A;  5INI A;  4FB8 A;  3GF3 A;  5DUC A;  3FDU A;  3HE2 A;  3NJD A;  4JVT A;  3MT6 A;  4Q0G A;  1HNO A;  3DOR A;  4ELS A;  3KTG A;  2J5I B;  3L3S A;  3PE8 A;  3TDC A;  3Q0G A;  2ZQQ A;  4GHN A;  2BZR A;  2C8T A;  4Q1I A;  1UYR A;  4I4Z A;  4FZW A;  2J5I A;  3H0Q A;  4MI2 A;  2ZL2 A;  3TZ3 A;  2GTR A;  5FIF A;  3T8A A;  3KTK A;  1FC7 A;  1XNY A;  3T8B A;  2FW2 A;  4RYF A;  5JBX A;  2F6Q A;  3R0O A;  4NNQ A;  2X58 A;  4MXI A;  5G1S A;  3HRX A;  1XO6 A;  4JYJ A;  5C9G A;  3ISA A;  4ZDF A;  3OT6 A;  4ZDD A;  5DTP A;  4I52 A;  3U9S B;  3QK8 A;  3T88 A;  4RYF H;  4JSB A;  2J5G D;  2CBY A;  4ASI A;  2VSS A;  4KD6 A;  4OMR A;  4NEK A;  1UYT A;  4HDT A;  5HUQ A;  4ZDC A;  5DU6 A;  3Q1T A;  4ZDE A;  4QIJ A;  4U18 A;  3QYR A;  4IZC A;  1WZ8 A;  2Q35 A;  5JBW A;  4YLH A;  1VRG A;  1UYS A;  3GMA A;  4FN8 A;  3RST A;  3GLM A;  3P85 A;  4B3J A;  4JYL A;  1RJN A;  2PG8 A;  4B3H A;  4J2U A;  2DEO A;  4FZW C;  5INF A;  3H02 A;  2X24 A;  4EMP A;  1XNW A;  4KWB A;  1MJ3 A;  3TT7 A;  4LK5 A;  3LAO A;  4JCQ A;  3KTJ A;  1FC6 A;  1FC9 A;  1NZY B;  3RRV A;  5DZK H;  2A7K A;  5E0S H;  4QII A;  4G2R A;  1PIX A;  1N6F A;  4HC8 A;  1XX4 A;  2VSU A;  4FND A;  4EMM A;  3R6H A;  2VRE A;  3U9T B;  3FF6 A;  3HLN 1;  1K39 A;  4GM2 A;  4JWV A;  4ZDB A;  3LKE A;  2F6I A;  3VIV A;  2PPY A;  1PJH A;  3TVU A;  3PZK A;  2ZL4 A;  4K29 A;  4JJT A;  5G1R A;  1SG4 A;  2VSS E;  3ZW9 A;  4U1A A;  1HNU A;  1WDL A;  3TVW A;  3BEZ A;  3H0J A;  1JXZ A;  1UYV A;  5G1Q A;  3BPP A;  2W3P A;  3ZWC A;  4WYO B;  4WCZ A;  3R9Q A;  2FZS A;  2VX2 A;  3TRR A;  4JFC A;  1N6E A;  4FNB A;  5DZK A;  5C90 A;  4F47 A;  3QWD A;  1YG6 A;  1N6D A;  3M6M A;  3G64 A;  1TG6 A;  2VSU F;  3T89 A;  1O8U A;  5ING A;  4U19 A;  3HIN A;  4JCS A;  2F9I A;  1UIY A;  1EF8 A;  1OD4 A;  3MFM A;  3H0S A;  5MGB A;  3K8X A;  5KDR A;  4Z0M A;  3MOY A;  1NZY A;  2VSU C;  3QMJ A;  2Q34 A;  2F9I B;  3MYB A;  4FN7 A;  3K50 A;  4WZ8 B;  2VSS F;  1EY3 A;  3SLL A;  3M6N A;  5FUS A;  2CE3 A;  3IBB A;  3KTH A;  2VSU E;  3QXZ A;  3H0U A;  1ON9 A;  3ST9 A;  1X0U A;  3WG5 A;  1Q52 A;  3ZWA A;  5CTB A;  3NJB A;  2ZL3 A;  4ELX A;  3Q0J A;  2PBP A;  5KJP A;  3QXI A;  1EF9 A;  3PEA A;  4KNP A;  4DI1 A;  2HW5 A;  4IZB A;  3U9R B;  3N6R B;  1ON3 A;  2IEX A;  3T3W A;  2J5S A;  3I47 A;  4JCT A;  3TLF A;  4JOT A;  3TV5 A;  4U0H A;  1RJM A;  3P5M A;  4ELW A;  2F9Y B;  3QKA A;  4IZD A;  4RCN A;  4I42 A; 
#chains in the Genus database with same CATH homology
 2J5I I;  2FBM A;  3SWX A;  4B3I A;  2QQ3 A;  2F9Y A;  4L8K A;  2YJG A;  1K32 A;  3RSI A;  3OC7 A;  1WDM A;  5DU4 A;  3R9S A;  3BF0 A;  3STA A;  5DUF A;  3P2L A;  3V5E A;  5DL1 A;  3ZWB A;  5KDR B;  3GKB A;  3JU1 A;  4EML A;  4U0G H;  4QFE A;  2UZF A;  3ZW8 A;  4NAR A;  3OME A;  4HNK A;  2A7S A;  3PGQ A;  1DUB A;  1HZD A;  5CTC A;  4OG1 A;  3KTI A;  3HP0 A;  5DTW A;  1DCI A;  4FJW D;  2D3T A;  3R9T A;  3IB9 A;  4L6W A;  3QRE A;  1WDK A;  3BPT A;  1J7X A;  2EJ5 A;  4U0G A;  3H81 A;  5DKP A;  4K3W A;  4OLQ A;  1XNV A;  2J5G A;  1OD2 A;  3TT6 A;  2ZQR A;  3DJA A;  5IKL B;  1W2X A;  1YG8 A;  5E0N X;  4JCR A;  1SZO A;  5E0S A;  3KQF A;  3IAV A;  5DU8 A;  4MOU A;  1Y7O A;  2NP9 A;  1TYF A;  2ZL0 A;  3GF7 A;  4KPK A;  4K2N A;  1Q51 A;  2Q2X A;  4ZU2 A;  2DUB A;  2WTB A;  2A81 A;  1FCF A;  3Q7H A;  3V5I A;  5INI A;  4FB8 A;  3GF3 A;  5DUC A;  3FDU A;  3HE2 A;  3NJD A;  4JVT A;  3MT6 A;  4Q0G A;  1HNO A;  3DOR A;  4ELS A;  3KTG A;  2J5I B;  3L3S A;  3PE8 A;  3TDC A;  3Q0G A;  2ZQQ A;  4GHN A;  2BZR A;  2C8T A;  4Q1I A;  1UYR A;  4I4Z A;  4FZW A;  2J5I A;  3H0Q A;  4MI2 A;  2ZL2 A;  3TZ3 A;  2GTR A;  5FIF A;  3T8A A;  3KTK A;  1FC7 A;  1XNY A;  3T8B A;  2FW2 A;  4RYF A;  5JBX A;  2F6Q A;  3R0O A;  4NNQ A;  2X58 A;  4MXI A;  5G1S A;  3HRX A;  1XO6 A;  4JYJ A;  5C9G A;  3ISA A;  4ZDF A;  3OT6 A;  4ZDD A;  5DTP A;  4I52 A;  3U9S B;  3QK8 A;  3T88 A;  4RYF H;  4JSB A;  2J5G D;  2CBY A;  4ASI A;  2VSS A;  4KD6 A;  4OMR A;  4NEK A;  1UYT A;  4HDT A;  5HUQ A;  4ZDC A;  5DU6 A;  3Q1T A;  4ZDE A;  4QIJ A;  4U18 A;  3QYR A;  4IZC A;  1WZ8 A;  2Q35 A;  5JBW A;  4YLH A;  1VRG A;  1UYS A;  3GMA A;  4FN8 A;  3RST A;  3GLM A;  3P85 A;  4B3J A;  4JYL A;  1RJN A;  2PG8 A;  4B3H A;  4J2U A;  2DEO A;  4FZW C;  5INF A;  3H02 A;  2X24 A;  4EMP A;  1XNW A;  4KWB A;  1MJ3 A;  3TT7 A;  4LK5 A;  3LAO A;  4JCQ A;  3KTJ A;  1FC6 A;  1FC9 A;  1NZY B;  3RRV A;  5DZK H;  2A7K A;  5E0S H;  4QII A;  4G2R A;  1PIX A;  1N6F A;  4HC8 A;  1XX4 A;  2VSU A;  4FND A;  4EMM A;  3R6H A;  2VRE A;  3U9T B;  3FF6 A;  3HLN 1;  1K39 A;  4GM2 A;  4JWV A;  4ZDB A;  3LKE A;  2F6I A;  3VIV A;  2PPY A;  1PJH A;  3TVU A;  3PZK A;  2ZL4 A;  4K29 A;  4JJT A;  5G1R A;  1SG4 A;  2VSS E;  3ZW9 A;  4U1A A;  1HNU A;  1WDL A;  3TVW A;  3BEZ A;  3H0J A;  1JXZ A;  1UYV A;  5G1Q A;  3BPP A;  2W3P A;  3ZWC A;  4WYO B;  4WCZ A;  3R9Q A;  2FZS A;  2VX2 A;  3TRR A;  4JFC A;  1N6E A;  4FNB A;  5DZK A;  5C90 A;  4F47 A;  3QWD A;  1YG6 A;  1N6D A;  3M6M A;  3G64 A;  1TG6 A;  2VSU F;  3T89 A;  1O8U A;  5ING A;  4U19 A;  3HIN A;  4JCS A;  2F9I A;  1UIY A;  1EF8 A;  1OD4 A;  3MFM A;  3H0S A;  5MGB A;  3K8X A;  5KDR A;  4Z0M A;  3MOY A;  1NZY A;  2VSU C;  3QMJ A;  2Q34 A;  2F9I B;  3MYB A;  4FN7 A;  3K50 A;  4WZ8 B;  2VSS F;  1EY3 A;  3SLL A;  3M6N A;  5FUS A;  2CE3 A;  3IBB A;  3KTH A;  2VSU E;  3QXZ A;  3H0U A;  1ON9 A;  3ST9 A;  1X0U A;  3WG5 A;  1Q52 A;  3ZWA A;  5CTB A;  3NJB A;  2ZL3 A;  4ELX A;  3Q0J A;  2PBP A;  5KJP A;  3QXI A;  1EF9 A;  3PEA A;  4KNP A;  4DI1 A;  2HW5 A;  4IZB A;  3U9R B;  3N6R B;  1ON3 A;  2IEX A;  3T3W A;  2J5S A;  3I47 A;  4JCT A;  3TLF A;  4JOT A;  3TV5 A;  4U0H A;  1RJM A;  3P5M A;  4ELW A;  2F9Y B;  3QKA A;  4IZD A;  4RCN A;  4I42 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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