4X28C

Crystal structure of the chse4-chse5 complex from mycobacterium tuberculosis
Total Genus 129
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
129
sequence length
373
structure length
364
Chain Sequence
MDFTTTEAAQDLGGLVDTIVDAVCTPEHQRELDKLEQRFDRELWRKLIDAGILSSAAPESLGGDGFGVLEQVAVLVALGHQLAAVPYLESVVLAAGALARFGSPELQQGWGVSAVSGDRILTVALDGEMGEGPVQAAGTGHGYRLTGTRTQVGYGPVADAFLVPAETDSGAAVFLVAAGDPGVAVTALATTGLGSVGHLELNGAKVDAARRVGGTDVAVWLGTLSTLSRTAFQLGVLERGLQMTAEYARTREQFDRPIGSFQAVGQRLADGYIDVKGLRLTLTQAAWRVAEDPADIDVATAGFWAAEAGHRVAHTIVHVHGGVGVDTDHPVHRYFLAAKQTEFALGGATGQLRRIGRELAETPA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Unraveling Cholesterol Catabolism in Mycobacterium tuberculosis: ChsE4-ChsE5 alpha 2 beta 2 Acyl-CoA Dehydrogenase Initiates beta-Oxidation of 3-Oxo-cholest-4-en-26-oyl CoA.
pubmed doi rcsb
molecule tags Oxidoreductase
source organism Mycobacterium tuberculosis (strain atcc 25618 / h37rv)
molecule keywords Acyl-CoA dehydrogenase
total genus 129
structure length 364
sequence length 373
chains with identical sequence D
ec nomenclature
pdb deposition date 2014-11-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF00441 Acyl-CoA_dh_1 Acyl-CoA dehydrogenase, C-terminal domain
C PF02771 Acyl-CoA_dh_N Acyl-CoA dehydrogenase, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.540.10 Mainly Alpha Orthogonal Bundle Butyryl-Coa Dehydrogenase, subunit A; domain 1 Acyl-CoA dehydrogenase/oxidase, N-terminal domain 4x28C01
1.20.140.10 Mainly Alpha Up-down Bundle Butyryl-CoA Dehydrogenase, subunit A; domain 3 Butyryl-CoA Dehydrogenase, subunit A, domain 3 4x28C03
2.40.110.10 Mainly Beta Beta Barrel Butyryl-CoA Dehydrogenase, subunit A; domain 2 Butyryl-CoA Dehydrogenase, subunit A, domain 2 4x28C02
2JBRA 3MPJA 3D6BA 4M9AA 3FCJA 2WBIA 1T9GA 3TORA 3D1IA 3FO3A 2OT4A 2OR0A 4HR3A 3GQTA 2DVLA 2E81A 3RKHA 3L1TA 4L3ZA 3HWCA 2DDHA 4X28A 4N5FA 4L38A 3D9DA 3B96A 3UU9A 1UKWA 4O5MA 2JBTA 3GNCA 1EGCA 2EBAA 4KCFA 5K3HA 2A1TA 2RFQA 2YYIA 1IVHA 1R2JA 3BNFA 4KTOA 2UXWA 3NF4A 3LGQA 1U8VA 2R0MA 3MXLA 2J7AA 3LG1A 2RDZA 3D9GA 4DOYA 3X0XA 4ZYJA 1BUCA 4L3YA 4X28C 3II9A 3AFFA 5K3GA 4W9UA 2CX9A 3SF6A 3OWAA 3MPIA 1RX0A 2VR0A 3PFDA 3EOMA 3UBRA 2D29A 4ZXVA 4OO2A 1GU6A 1SIQA 4U83A 1QDBA 2REHA 1EGDA 2JBSA 2YYGA 3X0YA 3F29A 4IRNA 3SCEA 4JEKA 3S7WA 4G5EA 2Z1QA 2E80A 1JQIA 2FONA 2YYJA 2RF7A 2IX5A 3MDDA 4WJYA 4L1FA 1FS8A 2YYLA 2YYKA 2YYMA 1FS7A 1EGEA 3SWOA 3EONA 2R0NA 3D9EA 2PG0A 3GM6A 2ZAFA 1IS2A 3BNGA 2C0UA 1WS9A 2ZO5A 3MDEA 2VIGA 3M9VA 4Q0TA 3MMOA 4Q4UA 5K3IA 1OAHA 3BNHA 3TTBA 2JIFA 4RM7A 1SIRA 4NXLA 4Q17A 4Q5BA 5K3JA 3R7KA 3BNJA 1UDYA 2C12A 3D9FA 4L3XA 2IX6A 4Q1OA 3OWMA 3SXQA 4Q5CA 1FS9A 3OIBA 4IV6A 1W07A 3P4TA 4XVXA 3AFEA 4P13A 3MKHA
chains in the Genus database with same CATH superfamily
2JBRA 3N0RA 3MPJA 5B6BA 2VF1A 2Q8IA 1JM6A 2BU5A 2Q8HA 3D6BA 4M9AA 3FCJA 2BTZA 5M4KA 4AKGA 3Q22A 3C46A 2WBIA 1T9GA 3TORA 3D1IA 3FO3A 4JIOA 2OR0A 2OT4A 4HR3A 3GQTA 2DVLA 1GKXA 2E81A 4AI6A 4FF4A 4H7QA 3DJLA 3TZ5A 1K90A 3RKHA 4E02A 5M4MA 1X90A 5GJVE 1XFUA 3L1TA 1XFXA 4L3ZA 3HWCA 4V25A 4QICA 4FZ4A 2DDHA 3Q24A 3D2RA 2LFWA 2BU2A 4X28A 4N5FA 1R3BA 4L38A 3D9DA 1GKZA 2R03A 3B96A 4AKIA 4MP7A 3UU9A 1UKWA 2EBHX 3U33A 4O5MA 2E0AA 4P79A 4KSAA 2JBTA 3GNCA 1Y8OA 4F0XA 4JIZA 1EGCA 2EBAA 4KCFA 4AKHA 5K3HA 2A1TA 2RFQA 1X8ZA 2CJ7A 1IVHA 1R2JA 2YYIA 3CRLA 3CRKA 3BNFA 4KTOA 4LQQB 2UXWA 3NF4A 3LGQA 3CE2A 1U8VA 4H81A 4MPNA 2R0MA 3MXLA 2J7AA 2GBBA 4V26A 3LG1A 1Y0VA 2RDZA 5J6AA 3D9GA 4DOYA 4MP2A 3X0XA 5M4NA 4ZYJA 5BRMA 1BUCA 4L3YA 4X28C 3II9A 3AFFA 4FF2A 4LQSB 5K3GA 4W9UA 2CX9A 2EC5A 2CJ8A 3SF6A 1LVCA 1RJ4A 2CJ6A 2XS1A 4HKSA 4KSFA 3OWAA 3MPIA 4G97A 4H85A 1RX0A 2VR0A 3PFDA 3C3LA 2OEXA 4E00A 3EOMA 3VADA 4MPCA 3UBRA 2D29A 4ZXVA 2R05A 2ZDXA 1XFWA 1S26A 1GU6A 4OO2A 3VKGA 1SIQA 4U83A 1QDBA 1X91A 3Q0AA 2REHA 1EGDA 1XG2B 2JBSA 2YYGA 2FP2A 3X0YA 3F29A 4IRNA 3SCEA 2Q8GA 4JEKA 3S7WA 3X29A 4G5EA 2Z1QA 2E80A 1XFVA 2BU8A 2BU6A 1JQIA 2R02A 2FONA 2YYJA 1Y8PA 2RF7A 2IX5A 1PI1A 3MDDA 1K93A 4WJYA 4L1FA 1Y8NA 3TZ0A 4FF1A 2XQRB 2OJQA 2YGWA 1XFZA 5J71A 3VKHA 1FS8A 2FP1A 2YYLA 2XS8A 2YYKA 5M4PA 1GJVA 2YYMA 4E01A 1FS7A 1EGEA 2CJ5A 3SWOA 3EONA 2R0NA 3D9EA 2OEVA 2PG0A 1SC5A 3GM6A 2QR4A 2ZAFA 1IS2A 3BNGA 1RJ1A 1XFYA 2C0UA 2CJ4A 5BRKA 2PO4A 1SK6A 1WS9A 2ZO5A 3MDEA 3KMLA 4J1VA 2VIGA 3M9VA 1RP3A 2PNRA 4Q0TA 3MMOA 4Q4UA 4DZYA 5K3IA 4HKRA 1OAHA 4FF3A 3BNHA 3TTBA 4MPEA 2JIFA 4RM7A 2BU7A 1SIRA 4NXLA 1K8TA 4Q17A 3TZ2A 3Q23A 4Q5BA 5B5VA 5K3JA 3R7KA 2AZEA 1UDYA 3BNJA 2C12A 3D9FA 4L3XA 3TZ4A 2Q8FA 5GJWE 2IX6A 4Q1OA 3C2PA 3OWMA 2EBFX 3SXQA 1PK0A 2ZKJA 4Q5CA 5B5WA 1FS9A 3OIBA 4IV6A 2F6LA 1W07A 3P4TA 4KS9A 2HJNA 4XVXA 2AO2A 2ZDYA 3AFEA 4P13A 5EZ3A 3MKHA
chains in the Genus database with same CATH topology
2JBRA 3MPJA 3D6BA 4M9AA 3FCJA 2WBIA 1T9GA 3TORA 3D1IA 3FO3A 2OT4A 2OR0A 4HR3A 3GQTA 2DVLA 2E81A 3RKHA 3L1TA 4L3ZA 3HWCA 2DDHA 4X28A 4N5FA 4L38A 3D9DA 3B96A 3UU9A 1UKWA 4O5MA 2JBTA 3GNCA 1EGCA 2EBAA 4KCFA 5K3HA 2A1TA 2RFQA 2YYIA 1IVHA 1R2JA 3BNFA 4KTOA 2UXWA 3NF4A 3LGQA 1U8VA 2R0MA 3MXLA 2J7AA 3LG1A 2RDZA 3D9GA 4DOYA 3X0XA 4ZYJA 1BUCA 4L3YA 4X28C 3II9A 3AFFA 5K3GA 4W9UA 2CX9A 3SF6A 3OWAA 3MPIA 1RX0A 2VR0A 3PFDA 3EOMA 3UBRA 2D29A 4ZXVA 4OO2A 1GU6A 1SIQA 4U83A 1QDBA 2REHA 1EGDA 2JBSA 2YYGA 3X0YA 3F29A 4IRNA 3SCEA 4JEKA 3S7WA 4G5EA 2Z1QA 2E80A 1JQIA 2FONA 2YYJA 2RF7A 2IX5A 3MDDA 4WJYA 4L1FA 1FS8A 2YYLA 2YYKA 2YYMA 1FS7A 1EGEA 3SWOA 3EONA 2R0NA 3D9EA 2PG0A 3GM6A 2ZAFA 1IS2A 3BNGA 2C0UA 1WS9A 2ZO5A 3MDEA 2VIGA 3M9VA 4Q0TA 3MMOA 4Q4UA 5K3IA 1OAHA 3BNHA 3TTBA 2JIFA 4RM7A 1SIRA 4NXLA 4Q17A 4Q5BA 5K3JA 3R7KA 3BNJA 1UDYA 2C12A 3D9FA 4L3XA 2IX6A 4Q1OA 3OWMA 3SXQA 4Q5CA 1FS9A 3OIBA 4IV6A 1W07A 3P4TA 4XVXA 3AFEA 4P13A 3MKHA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JBR A;  3MPJ A;  3D6B A;  4M9A A;  3FCJ A;  2WBI A;  1T9G A;  3TOR A;  3D1I A;  3FO3 A;  2OT4 A;  2OR0 A;  4HR3 A;  3GQT A;  2DVL A;  2E81 A;  3RKH A;  3L1T A;  4L3Z A;  3HWC A;  2DDH A;  4X28 A;  4N5F A;  4L38 A;  3D9D A;  3B96 A;  3UU9 A;  1UKW A;  4O5M A;  2JBT A;  3GNC A;  1EGC A;  2EBA A;  4KCF A;  5K3H A;  2A1T A;  2RFQ A;  2YYI A;  1IVH A;  1R2J A;  3BNF A;  4KTO A;  2UXW A;  3NF4 A;  3LGQ A;  1U8V A;  2R0M A;  3MXL A;  2J7A A;  3LG1 A;  2RDZ A;  3D9G A;  4DOY A;  3X0X A;  4ZYJ A;  1BUC A;  4L3Y A;  4X28 C;  3II9 A;  3AFF A;  5K3G A;  4W9U A;  2CX9 A;  3SF6 A;  3OWA A;  3MPI A;  1RX0 A;  2VR0 A;  3PFD A;  3EOM A;  3UBR A;  2D29 A;  4ZXV A;  4OO2 A;  1GU6 A;  1SIQ A;  4U83 A;  1QDB A;  2REH A;  1EGD A;  2JBS A;  2YYG A;  3X0Y A;  3F29 A;  4IRN A;  3SCE A;  4JEK A;  3S7W A;  4G5E A;  2Z1Q A;  2E80 A;  1JQI A;  2FON A;  2YYJ A;  2RF7 A;  2IX5 A;  3MDD A;  4WJY A;  4L1F A;  1FS8 A;  2YYL A;  2YYK A;  2YYM A;  1FS7 A;  1EGE A;  3SWO A;  3EON A;  2R0N A;  3D9E A;  2PG0 A;  3GM6 A;  2ZAF A;  1IS2 A;  3BNG A;  2C0U A;  1WS9 A;  2ZO5 A;  3MDE A;  2VIG A;  3M9V A;  4Q0T A;  3MMO A;  4Q4U A;  5K3I A;  1OAH A;  3BNH A;  3TTB A;  2JIF A;  4RM7 A;  1SIR A;  4NXL A;  4Q17 A;  4Q5B A;  5K3J A;  3R7K A;  3BNJ A;  1UDY A;  2C12 A;  3D9F A;  4L3X A;  2IX6 A;  4Q1O A;  3OWM A;  3SXQ A;  4Q5C A;  1FS9 A;  3OIB A;  4IV6 A;  1W07 A;  3P4T A;  4XVX A;  3AFE A;  4P13 A;  3MKH A; 
#chains in the Genus database with same CATH topology
 2JBR A;  3N0R A;  3MPJ A;  5B6B A;  2VF1 A;  2Q8I A;  1JM6 A;  2BU5 A;  2Q8H A;  3D6B A;  4M9A A;  3FCJ A;  2BTZ A;  5M4K A;  4AKG A;  3Q22 A;  3C46 A;  2WBI A;  1T9G A;  3TOR A;  3D1I A;  3FO3 A;  4JIO A;  2OR0 A;  2OT4 A;  4HR3 A;  3GQT A;  2DVL A;  1GKX A;  2E81 A;  4AI6 A;  4FF4 A;  4H7Q A;  3DJL A;  3TZ5 A;  1K90 A;  3RKH A;  4E02 A;  5M4M A;  1X90 A;  5GJV E;  1XFU A;  3L1T A;  1XFX A;  4L3Z A;  3HWC A;  4V25 A;  4QIC A;  4FZ4 A;  2DDH A;  3Q24 A;  3D2R A;  2LFW A;  2BU2 A;  4X28 A;  4N5F A;  1R3B A;  4L38 A;  3D9D A;  1GKZ A;  2R03 A;  3B96 A;  4AKI A;  4MP7 A;  3UU9 A;  1UKW A;  2EBH X;  3U33 A;  4O5M A;  2E0A A;  4P79 A;  4KSA A;  2JBT A;  3GNC A;  1Y8O A;  4F0X A;  4JIZ A;  1EGC A;  2EBA A;  4KCF A;  4AKH A;  5K3H A;  2A1T A;  2RFQ A;  1X8Z A;  2CJ7 A;  1IVH A;  1R2J A;  2YYI A;  3CRL A;  3CRK A;  3BNF A;  4KTO A;  4LQQ B;  2UXW A;  3NF4 A;  3LGQ A;  3CE2 A;  1U8V A;  4H81 A;  4MPN A;  2R0M A;  3MXL A;  2J7A A;  2GBB A;  4V26 A;  3LG1 A;  1Y0V A;  2RDZ A;  5J6A A;  3D9G A;  4DOY A;  4MP2 A;  3X0X A;  5M4N A;  4ZYJ A;  5BRM A;  1BUC A;  4L3Y A;  4X28 C;  3II9 A;  3AFF A;  4FF2 A;  4LQS B;  5K3G A;  4W9U A;  2CX9 A;  2EC5 A;  2CJ8 A;  3SF6 A;  1LVC A;  1RJ4 A;  2CJ6 A;  2XS1 A;  4HKS A;  4KSF A;  3OWA A;  3MPI A;  4G97 A;  4H85 A;  1RX0 A;  2VR0 A;  3PFD A;  3C3L A;  2OEX A;  4E00 A;  3EOM A;  3VAD A;  4MPC A;  3UBR A;  2D29 A;  4ZXV A;  2R05 A;  2ZDX A;  1XFW A;  1S26 A;  1GU6 A;  4OO2 A;  3VKG A;  1SIQ A;  4U83 A;  1QDB A;  1X91 A;  3Q0A A;  2REH A;  1EGD A;  1XG2 B;  2JBS A;  2YYG A;  2FP2 A;  3X0Y A;  3F29 A;  4IRN A;  3SCE A;  2Q8G A;  4JEK A;  3S7W A;  3X29 A;  4G5E A;  2Z1Q A;  2E80 A;  1XFV A;  2BU8 A;  2BU6 A;  1JQI A;  2R02 A;  2FON A;  2YYJ A;  1Y8P A;  2RF7 A;  2IX5 A;  1PI1 A;  3MDD A;  1K93 A;  4WJY A;  4L1F A;  1Y8N A;  3TZ0 A;  4FF1 A;  2XQR B;  2OJQ A;  2YGW A;  1XFZ A;  5J71 A;  3VKH A;  1FS8 A;  2FP1 A;  2YYL A;  2XS8 A;  2YYK A;  5M4P A;  1GJV A;  2YYM A;  4E01 A;  1FS7 A;  1EGE A;  2CJ5 A;  3SWO A;  3EON A;  2R0N A;  3D9E A;  2OEV A;  2PG0 A;  1SC5 A;  3GM6 A;  2QR4 A;  2ZAF A;  1IS2 A;  3BNG A;  1RJ1 A;  1XFY A;  2C0U A;  2CJ4 A;  5BRK A;  2PO4 A;  1SK6 A;  1WS9 A;  2ZO5 A;  3MDE A;  3KML A;  4J1V A;  2VIG A;  3M9V A;  1RP3 A;  2PNR A;  4Q0T A;  3MMO A;  4Q4U A;  4DZY A;  5K3I A;  4HKR A;  1OAH A;  4FF3 A;  3BNH A;  3TTB A;  4MPE A;  2JIF A;  4RM7 A;  2BU7 A;  1SIR A;  4NXL A;  1K8T A;  4Q17 A;  3TZ2 A;  3Q23 A;  4Q5B A;  5B5V A;  5K3J A;  3R7K A;  2AZE A;  1UDY A;  3BNJ A;  2C12 A;  3D9F A;  4L3X A;  3TZ4 A;  2Q8F A;  5GJW E;  2IX6 A;  4Q1O A;  3C2P A;  3OWM A;  2EBF X;  3SXQ A;  1PK0 A;  2ZKJ A;  4Q5C A;  5B5W A;  1FS9 A;  3OIB A;  4IV6 A;  2F6L A;  1W07 A;  3P4T A;  4KS9 A;  2HJN A;  4XVX A;  2AO2 A;  2ZDY A;  3AFE A;  4P13 A;  5EZ3 A;  3MKH A; 
#chains in the Genus database with same CATH homology
 2JBR A;  3MPJ A;  3D6B A;  4M9A A;  3FCJ A;  2WBI A;  1T9G A;  3TOR A;  3D1I A;  3FO3 A;  2OT4 A;  2OR0 A;  4HR3 A;  3GQT A;  2DVL A;  2E81 A;  3RKH A;  3L1T A;  4L3Z A;  3HWC A;  2DDH A;  4X28 A;  4N5F A;  4L38 A;  3D9D A;  3B96 A;  3UU9 A;  1UKW A;  4O5M A;  2JBT A;  3GNC A;  1EGC A;  2EBA A;  4KCF A;  5K3H A;  2A1T A;  2RFQ A;  2YYI A;  1IVH A;  1R2J A;  3BNF A;  4KTO A;  2UXW A;  3NF4 A;  3LGQ A;  1U8V A;  2R0M A;  3MXL A;  2J7A A;  3LG1 A;  2RDZ A;  3D9G A;  4DOY A;  3X0X A;  4ZYJ A;  1BUC A;  4L3Y A;  4X28 C;  3II9 A;  3AFF A;  5K3G A;  4W9U A;  2CX9 A;  3SF6 A;  3OWA A;  3MPI A;  1RX0 A;  2VR0 A;  3PFD A;  3EOM A;  3UBR A;  2D29 A;  4ZXV A;  4OO2 A;  1GU6 A;  1SIQ A;  4U83 A;  1QDB A;  2REH A;  1EGD A;  2JBS A;  2YYG A;  3X0Y A;  3F29 A;  4IRN A;  3SCE A;  4JEK A;  3S7W A;  4G5E A;  2Z1Q A;  2E80 A;  1JQI A;  2FON A;  2YYJ A;  2RF7 A;  2IX5 A;  3MDD A;  4WJY A;  4L1F A;  1FS8 A;  2YYL A;  2YYK A;  2YYM A;  1FS7 A;  1EGE A;  3SWO A;  3EON A;  2R0N A;  3D9E A;  2PG0 A;  3GM6 A;  2ZAF A;  1IS2 A;  3BNG A;  2C0U A;  1WS9 A;  2ZO5 A;  3MDE A;  2VIG A;  3M9V A;  4Q0T A;  3MMO A;  4Q4U A;  5K3I A;  1OAH A;  3BNH A;  3TTB A;  2JIF A;  4RM7 A;  1SIR A;  4NXL A;  4Q17 A;  4Q5B A;  5K3J A;  3R7K A;  3BNJ A;  1UDY A;  2C12 A;  3D9F A;  4L3X A;  2IX6 A;  4Q1O A;  3OWM A;  3SXQ A;  4Q5C A;  1FS9 A;  3OIB A;  4IV6 A;  1W07 A;  3P4T A;  4XVX A;  3AFE A;  4P13 A;  3MKH A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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