The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
115
|
sequence length |
347
|
structure length |
347
|
Chain Sequence |
VPSWPQILGRLTDNRDLARGQAAWAMDQIMTGNARPAQIAAFAVAMTMKAPTADEVGELAGVMLSHAHPLPADTVPDDAVDVVGTGGDGVNTVNLSTMAAIVVAAAGVPVVKHGNRAASSLSGGADTLEALGVRIDLGPDLVARSLAEVGIGFCFAPRFHPSYRHAAAVLREIGVPTVFNLLGPLTNPARPRAGLIGCAFADLAEVMAGVFAARRSSVLVVHGDDGLDELTTTTTSTIWRVAAGSVDKLTFDPAGFGFARAQLDQLAGGDAQANAAAVRAVLGGARGPVRDAVVLNAAGAIVAHAGLSSRAEWLPAWEEGLRRASAAIDTGAAEQLLARWVRFGRQI
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.
pubmed doi rcsb |
| molecule tags |
Transferase
|
| source organism |
Mycobacterium tuberculosis
|
| molecule keywords |
Anthranilate phosphoribosyltransferase
|
| total genus |
115
|
| structure length |
347
|
| sequence length |
347
|
| chains with identical sequence |
B
|
| ec nomenclature |
ec
2.4.2.18: Anthranilate phosphoribosyltransferase. |
| pdb deposition date | 2014-12-05 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00591 | Glycos_transf_3 | Glycosyl transferase family, a/b domain |
| A | PF02885 | Glycos_trans_3N | Glycosyl transferase family, helical bundle domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Alpha | Up-down Bundle | Transferase, Pyrimidine Nucleoside Phosphorylase; Chain A, domain 3 | Transferase, Pyrimidine Nucleoside Phosphorylase; Chain C | ||
| Alpha Beta | 3-Layer(aba) Sandwich | Pyrimidine Nucleoside Phosphorylase; Chain A, domain 2 | Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain |
#chains in the Genus database with same CATH superfamily 2WK5 A; 4N5V A; 4GA4 A; 1ZYK A; 4ZTV A; 3TWP A; 4EAD A; 4X58 A; 4X5C A; 4OWN A; 4N8Q A; 4GTN A; 4YI7 A; 2ELC A; 1ZVW A; 4GA5 A; 1KHD A; 1OTP A; 4X5E A; 4OWS A; 1V8G A; 2WK6 A; 1VQU A; 3QR9 A; 3R88 A; 1ZXY A; 3QS8 A; 3GBR A; 1UOU A; 4M0R A; 4OWQ A; 1O17 A; 4OWM A; 4ZOK A; 1BRW A; 1KGZ A; 3QQS A; 4X5B A; 4ZOF A; 4GKM A; 4GIU A; 2DSJ A; 4LHM A; 3R6C A; 5BO2 A; 2J0F A; 3UU1 A; 1AZY A; 5C2L A; 3H5Q A; 4YYY A; 2GVQ A; 5EY3 A; 4X59 A; 4ZOJ A; 4MUO A; 5EP8 A; 4X5D A; 4GA6 A; 5C1R A; 4YEK A; 4N93 A; 4HKM A; 4OWU A; 5BYT A; 2TPT A; 3QSA A; 4OWO A; 4X46 A; 5BO3 A; 1GXB A; 4EAF A; 4IJ1 A; 2BPQ A; 5C7S A; 5BNE A; 4OWV A; 4X5A A; 4XR5 A; #chains in the Genus database with same CATH topology 2WK5 A; 4N5V A; 4GA4 A; 1ZYK A; 4ZTV A; 3TWP A; 4EAD A; 4X58 A; 4X5C A; 4OWN A; 4N8Q A; 4GTN A; 4YI7 A; 2ELC A; 1ZVW A; 4GA5 A; 1KHD A; 1OTP A; 4X5E A; 4OWS A; 1V8G A; 2WK6 A; 1VQU A; 3QR9 A; 3R88 A; 1ZXY A; 3QS8 A; 3GBR A; 1UOU A; 4M0R A; 4OWQ A; 1O17 A; 4OWM A; 4ZOK A; 1BRW A; 1KGZ A; 3QQS A; 4X5B A; 1RRZ A; 4ZOF A; 4GKM A; 4GIU A; 2DSJ A; 4LHM A; 3R6C A; 5BO2 A; 2J0F A; 3UU1 A; 1AZY A; 5C2L A; 3H5Q A; 4YYY A; 2GVQ A; 5EY3 A; 4X59 A; 4ZOJ A; 4MUO A; 5EP8 A; 4X5D A; 4GA6 A; 5C1R A; 4YEK A; 4F3F C; 4N93 A; 4HKM A; 4OWU A; 5BYT A; 2TPT A; 3QSA A; 4OWO A; 4X46 A; 5BO3 A; 1RF8 B; 1GXB A; 4EAF A; 4IJ1 A; 2BPQ A; 5C7S A; 5BNE A; 4OWV A; 4X5A A; 4XR5 A; #chains in the Genus database with same CATH homology 2WK5 A; 4N5V A; 4GA4 A; 1ZYK A; 4ZTV A; 3TWP A; 4EAD A; 4X58 A; 4X5C A; 4OWN A; 4N8Q A; 4GTN A; 4YI7 A; 2ELC A; 1ZVW A; 4GA5 A; 1KHD A; 1OTP A; 4X5E A; 4OWS A; 1V8G A; 2WK6 A; 1VQU A; 3QR9 A; 3R88 A; 1ZXY A; 3QS8 A; 3GBR A; 1UOU A; 4M0R A; 4OWQ A; 1O17 A; 4OWM A; 4ZOK A; 1BRW A; 1KGZ A; 3QQS A; 4X5B A; 4ZOF A; 4GKM A; 4GIU A; 2DSJ A; 4LHM A; 3R6C A; 5BO2 A; 2J0F A; 3UU1 A; 1AZY A; 5C2L A; 3H5Q A; 4YYY A; 2GVQ A; 5EY3 A; 4X59 A; 4ZOJ A; 4MUO A; 5EP8 A; 4X5D A; 4GA6 A; 5C1R A; 4YEK A; 4N93 A; 4HKM A; 4OWU A; 5BYT A; 2TPT A; 3QSA A; 4OWO A; 4X46 A; 5BO3 A; 1GXB A; 4EAF A; 4IJ1 A; 2BPQ A; 5C7S A; 5BNE A; 4OWV A; 4X5A A; 4XR5 A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
