4XQAA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0462
Total Genus 44
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
44
sequence length
184
structure length
184
Chain Sequence
DTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule tags Viral protein
source organism Human adenovirus 37
molecule keywords Fiber
total genus 44
structure length 184
sequence length 184
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2015-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4xqaA00
1UXBA 2J1KC 4LIYA 1UXEA 2WGUA 4WYJA 1H7ZA 3BQ4A 3EXVA 1NOBA 2J2JA 4K6TA 3QNDA 2WSTA 1QHVA 1P69A 1KNBA 4ZDGA 2J12A 4K6UA 2BZVA 2WBWA 3F0YA 4XQAA 1UXAA 2WBVA 4XQBA 2O39A 4K6VA 2WGTA 2BZUA 3L89A 4K6WA 1KACA 4XL8A 3O8EA 3L88A 3N0IA 3EXWA 3CNCA 2QLKA 2W9LC 1QIUA 4ATZA 1P6AA
chains in the Genus database with same CATH superfamily
2VTWA 1UXBA 2J1KC 4LIYA 1UXEA 2WGUA 4WYJA 4D62A 1H7ZA 2VRSA 3BQ4A 1NOBA 2J2JA 3EXVA 1KKEA 2OJ6A 3QNDA 4K6TA 2IUMA 2WSTA 1QHVA 1P69A 2BT8A 4GU4A 1KNBA 4ZDGA 2J12A 4XC5A 3EOYA 2BZVA 4K6UA 2BSFA 2WBWA 5MHSA 3F0YA 4XQAA 1UXAA 2WBVA 4XQBA 2O39A 4K6VA 2WGTA 3ZPEA 3S6XA 2BZUA 4D63A 4GU3A 2OJ5A 3L89A 4K6WA 1KACA 4XL8A 3O8EA 3L88A 4CW8A 3N0IA 3EXWA 4ODBA 3CNCA 2QLKA 2JJLA 2W9LC 1QIUA 2IUNA 2BT7A 4ATZA 3ZPFA 1P6AA
chains in the Genus database with same CATH topology
1UXBA 2J1KC 4LIYA 1UXEA 2WGUA 4WYJA 1H7ZA 3BQ4A 3EXVA 1NOBA 2J2JA 4K6TA 3QNDA 2WSTA 1QHVA 1P69A 1KNBA 4ZDGA 2J12A 4K6UA 2BZVA 2WBWA 3F0YA 4XQAA 1UXAA 2WBVA 4XQBA 2O39A 4K6VA 2WGTA 2BZUA 3L89A 4K6WA 1KACA 4XL8A 3O8EA 3L88A 3N0IA 3EXWA 3CNCA 2QLKA 2W9LC 1QIUA 4ATZA 1P6AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UXB A;  2J1K C;  4LIY A;  1UXE A;  2WGU A;  4WYJ A;  1H7Z A;  3BQ4 A;  3EXV A;  1NOB A;  2J2J A;  4K6T A;  3QND A;  2WST A;  1QHV A;  1P69 A;  1KNB A;  4ZDG A;  2J12 A;  4K6U A;  2BZV A;  2WBW A;  3F0Y A;  4XQA A;  1UXA A;  2WBV A;  4XQB A;  2O39 A;  4K6V A;  2WGT A;  2BZU A;  3L89 A;  4K6W A;  1KAC A;  4XL8 A;  3O8E A;  3L88 A;  3N0I A;  3EXW A;  3CNC A;  2QLK A;  2W9L C;  1QIU A;  4ATZ A;  1P6A A; 
#chains in the Genus database with same CATH topology
 2VTW A;  1UXB A;  2J1K C;  4LIY A;  1UXE A;  2WGU A;  4WYJ A;  4D62 A;  1H7Z A;  2VRS A;  3BQ4 A;  1NOB A;  2J2J A;  3EXV A;  1KKE A;  2OJ6 A;  3QND A;  4K6T A;  2IUM A;  2WST A;  1QHV A;  1P69 A;  2BT8 A;  4GU4 A;  1KNB A;  4ZDG A;  2J12 A;  4XC5 A;  3EOY A;  2BZV A;  4K6U A;  2BSF A;  2WBW A;  5MHS A;  3F0Y A;  4XQA A;  1UXA A;  2WBV A;  4XQB A;  2O39 A;  4K6V A;  2WGT A;  3ZPE A;  3S6X A;  2BZU A;  4D63 A;  4GU3 A;  2OJ5 A;  3L89 A;  4K6W A;  1KAC A;  4XL8 A;  3O8E A;  3L88 A;  4CW8 A;  3N0I A;  3EXW A;  4ODB A;  3CNC A;  2QLK A;  2JJL A;  2W9L C;  1QIU A;  2IUN A;  2BT7 A;  4ATZ A;  3ZPF A;  1P6A A; 
#chains in the Genus database with same CATH homology
 1UXB A;  2J1K C;  4LIY A;  1UXE A;  2WGU A;  4WYJ A;  1H7Z A;  3BQ4 A;  3EXV A;  1NOB A;  2J2J A;  4K6T A;  3QND A;  2WST A;  1QHV A;  1P69 A;  1KNB A;  4ZDG A;  2J12 A;  4K6U A;  2BZV A;  2WBW A;  3F0Y A;  4XQA A;  1UXA A;  2WBV A;  4XQB A;  2O39 A;  4K6V A;  2WGT A;  2BZU A;  3L89 A;  4K6W A;  1KAC A;  4XL8 A;  3O8E A;  3L88 A;  3N0I A;  3EXW A;  3CNC A;  2QLK A;  2W9L C;  1QIU A;  4ATZ A;  1P6A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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