4XQBA

Crystal structure of ad37 fiber knob in complex with trivalent sialic acid inhibitor me0461
Total Genus 46
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
46
sequence length
184
structure length
184
Chain Sequence
DTRTLWTTPDTSPNCTIAQDKDSKLTLVLTKCGSQILANVSLIVVAGKYHIINNKTNPKIKSFTIKLLFNKNGVLLDNSNLGKAYWNFRSGNSNVSTAYEKAIGFMPNLVAYPKPSNSKKYARDIVYGTIYLGGKPDQPAVIKTTFNQETGCEYSITFNFSWSKTYENVEFETTSFTFSYIAQE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.
pubmed doi rcsb
molecule tags Viral protein
source organism Human adenovirus 37
molecule keywords Fiber
total genus 46
structure length 184
sequence length 184
chains with identical sequence B, C
ec nomenclature
pdb deposition date 2015-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00541 Adeno_knob Adenoviral fibre protein (knob domain)
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.90.10 Mainly Beta Sandwich Adenovirus Type 5 Fiber Protein (Receptor Binding Domain) Adenovirus pIV-related, attachment domain 4xqbA00
2J2JA 3F0YA 4XL8A 4XQBA 3L88A 4K6VA 4K6UA 1UXBA 3BQ4A 2W9LC 2WGUA 1P69A 1P6AA 1QHVA 3O8EA 2QLKA 2WSTA 2BZVA 2WBVA 2WGTA 1H7ZA 1UXAA 3N0IA 4ZDGA 3EXVA 4ATZA 3EXWA 4WYJA 1QIUA 1KNBA 4K6WA 1UXEA 3QNDA 2J1KC 1KACA 2BZUA 3L89A 3CNCA 2WBWA 4LIYA 4XQAA 4K6TA 2J12A 1NOBA 2O39A
chains in the Genus database with same CATH superfamily
2J2JA 2VRSA 3F0YA 4XL8A 3L88A 4K6VA 4XQBA 3S6XA 4K6UA 1UXBA 3BQ4A 2OJ5A 2W9LC 2WGUA 4GU3A 1P69A 1P6AA 1QHVA 4CW8A 2OJ6A 3O8EA 3EOYA 2QLKA 3ZPEA 4GU4A 2WSTA 2BT8A 2VTWA 3ZPFA 2BZVA 1KKEA 2WBVA 2WGTA 4XC5A 1H7ZA 1UXAA 3N0IA 4ZDGA 2BSFA 3EXVA 4ATZA 3EXWA 4WYJA 1QIUA 1KNBA 2JJLA 4K6WA 5MHSA 1UXEA 3QNDA 2J1KC 1KACA 2BZUA 3L89A 4D62A 2BT7A 2IUNA 3CNCA 2IUMA 2WBWA 4LIYA 4D63A 4XQAA 4K6TA 4ODBA 2J12A 1NOBA 2O39A
chains in the Genus database with same CATH topology
2J2JA 3F0YA 4XL8A 4XQBA 3L88A 4K6VA 4K6UA 1UXBA 3BQ4A 2W9LC 2WGUA 1P69A 1P6AA 1QHVA 3O8EA 2QLKA 2WSTA 2BZVA 2WBVA 2WGTA 1H7ZA 1UXAA 3N0IA 4ZDGA 3EXVA 4ATZA 3EXWA 4WYJA 1QIUA 1KNBA 4K6WA 1UXEA 3QNDA 2J1KC 1KACA 2BZUA 3L89A 3CNCA 2WBWA 4LIYA 4XQAA 4K6TA 2J12A 1NOBA 2O39A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2J2J A;  3F0Y A;  4XL8 A;  4XQB A;  3L88 A;  4K6V A;  4K6U A;  1UXB A;  3BQ4 A;  2W9L C;  2WGU A;  1P69 A;  1P6A A;  1QHV A;  3O8E A;  2QLK A;  2WST A;  2BZV A;  2WBV A;  2WGT A;  1H7Z A;  1UXA A;  3N0I A;  4ZDG A;  3EXV A;  4ATZ A;  3EXW A;  4WYJ A;  1QIU A;  1KNB A;  4K6W A;  1UXE A;  3QND A;  2J1K C;  1KAC A;  2BZU A;  3L89 A;  3CNC A;  2WBW A;  4LIY A;  4XQA A;  4K6T A;  2J12 A;  1NOB A;  2O39 A; 
#chains in the Genus database with same CATH topology
 2J2J A;  2VRS A;  3F0Y A;  4XL8 A;  3L88 A;  4K6V A;  4XQB A;  3S6X A;  4K6U A;  1UXB A;  3BQ4 A;  2OJ5 A;  2W9L C;  2WGU A;  4GU3 A;  1P69 A;  1P6A A;  1QHV A;  4CW8 A;  2OJ6 A;  3O8E A;  3EOY A;  2QLK A;  3ZPE A;  4GU4 A;  2WST A;  2BT8 A;  2VTW A;  3ZPF A;  2BZV A;  1KKE A;  2WBV A;  2WGT A;  4XC5 A;  1H7Z A;  1UXA A;  3N0I A;  4ZDG A;  2BSF A;  3EXV A;  4ATZ A;  3EXW A;  4WYJ A;  1QIU A;  1KNB A;  2JJL A;  4K6W A;  5MHS A;  1UXE A;  3QND A;  2J1K C;  1KAC A;  2BZU A;  3L89 A;  4D62 A;  2BT7 A;  2IUN A;  3CNC A;  2IUM A;  2WBW A;  4LIY A;  4D63 A;  4XQA A;  4K6T A;  4ODB A;  2J12 A;  1NOB A;  2O39 A; 
#chains in the Genus database with same CATH homology
 2J2J A;  3F0Y A;  4XL8 A;  4XQB A;  3L88 A;  4K6V A;  4K6U A;  1UXB A;  3BQ4 A;  2W9L C;  2WGU A;  1P69 A;  1P6A A;  1QHV A;  3O8E A;  2QLK A;  2WST A;  2BZV A;  2WBV A;  2WGT A;  1H7Z A;  1UXA A;  3N0I A;  4ZDG A;  3EXV A;  4ATZ A;  3EXW A;  4WYJ A;  1QIU A;  1KNB A;  4K6W A;  1UXE A;  3QND A;  2J1K C;  1KAC A;  2BZU A;  3L89 A;  3CNC A;  2WBW A;  4LIY A;  4XQA A;  4K6T A;  2J12 A;  1NOB A;  2O39 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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