4XSHB

The complex structure of c3cer exoenzyme and gtp bound rhoa (nadh-bound state)
Total Genus 67
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
205
structure length
205
Chain Sequence
KYKLCTNKEEADAWGKKQFNKWSKEEKSAIRDYTKNARPYNEFLRMHAGKLDSDPTMKKKIESLDKALNRKEAKVNDNIKVYRGDDAWIFGKEYDNSIIKNGKVDREKFKEIQKKFQGKTTTEFGYISTSILIDAGYAKTRPVMTEFKVGSGTHGAYMNSDDLTAYPGQYELLLPRNTVYKIEKIYIAIDNNTQKEQIKVEATIK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Rho GTPase Recognition by C3 Exoenzyme Based on C3-RhoA Complex Structure.
pubmed doi rcsb
molecule keywords Transforming protein RhoA
molecule tags Signaling protein/transferase
source organism Homo sapiens
total genus 67
structure length 205
sequence length 205
ec nomenclature
pdb deposition date 2015-01-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4xshB00
4XM8A 1OG1A 3NTSA 4PKUA 3U0JA 2WN6A 1PWUA 1G24A 4TR5A 3BUZA 1QS2A 4ELNA 1PWWA 4H0VA 4FK7A 4XM7A 2J3XA 2WN4A 5D1UA 1OJQA 1GIRA 2J3VA 4H03A 4DV8A 5H03A 4PKWA 1PWPA 2WN5A 2WN8A 4H0YA 4XM6A 4PKTA 2C8CA 4GF1A 1OJZA 4PKVA 4PKRA 2C8FE 4XSHB 1GXYA 2GWMA 1JKYA 4PKSA 1J7NA 5GTTA 2BOVB 1GXZA 2J3ZA 2GWLA 2C8GA 4FMLA 1R45A 2C89A 2A9KB 1ZXVA 4GY2A 4WF6A 4FXQA 3BW8A 5H04A 1OG3A 2A78B 2C8HA 1GIQA 1R4BA 1UZIA 2C8AA 2C8BX 1GY0A 5D1TA 5DZQA 4XSGB 2C8DA 1QS1A 1GZEA 2WN7A 1PWQA 1GZFA 5BWMB 1OG4A 5D1SA 1YQYA 4H0TA 4H0XA 1PWVA 4PKQA 2C8EE
chains in the Genus database with same CATH superfamily
4XM8A 1OG1A 3NTSA 4PKUA 3U0JA 2WN6A 1PWUA 1G24A 4TR5A 3BUZA 1QS2A 4ELNA 1PWWA 4H0VA 4FK7A 4XM7A 2J3XA 2WN4A 5D1UA 1OJQA 1GIRA 2J3VA 4H03A 4DV8A 5H03A 4PKWA 1PWPA 2WN5A 2WN8A 4H0YA 4XM6A 4PKTA 2C8CA 4GF1A 1OJZA 4PKVA 4PKRA 2C8FE 4XSHB 1GXYA 2GWMA 1JKYA 4PKSA 1J7NA 5GTTA 2BOVB 1GXZA 2J3ZA 2GWLA 2C8GA 4FMLA 1R45A 2C89A 2A9KB 1ZXVA 4GY2A 4WF6A 4FXQA 3BW8A 5H04A 1OG3A 2A78B 2C8HA 1GIQA 1R4BA 1UZIA 2C8AA 2C8BX 1GY0A 5D1TA 5DZQA 4XSGB 2C8DA 1QS1A 1GZEA 2WN7A 1PWQA 1GZFA 5BWMB 1OG4A 5D1SA 1YQYA 4H0TA 4H0XA 1PWVA 4PKQA 2C8EE
chains in the Genus database with same CATH topology
4XM8A 1OG1A 3NTSA 4PKUA 3U0JA 2WN6A 1PWUA 1G24A 4TR5A 3BUZA 1QS2A 4ELNA 1PWWA 4H0VA 4FK7A 4XM7A 2J3XA 2WN4A 5D1UA 1OJQA 1GIRA 2J3VA 4H03A 4DV8A 5H03A 4PKWA 1PWPA 2WN5A 2WN8A 4H0YA 4XM6A 4PKTA 2C8CA 4GF1A 1OJZA 4PKVA 4PKRA 2C8FE 4XSHB 1GXYA 2GWMA 1JKYA 4PKSA 1J7NA 5GTTA 2BOVB 1GXZA 2J3ZA 2GWLA 2C8GA 4FMLA 1R45A 2C89A 2A9KB 1ZXVA 4GY2A 4WF6A 4FXQA 3BW8A 5H04A 1OG3A 2A78B 2C8HA 1GIQA 1R4BA 1UZIA 2C8AA 2C8BX 1GY0A 5D1TA 5DZQA 4XSGB 2C8DA 1QS1A 1GZEA 2WN7A 1PWQA 1GZFA 5BWMB 1OG4A 5D1SA 1YQYA 4H0TA 4H0XA 1PWVA 4PKQA 2C8EE
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XM8 A;  1OG1 A;  3NTS A;  4PKU A;  3U0J A;  2WN6 A;  1PWU A;  1G24 A;  4TR5 A;  3BUZ A;  1QS2 A;  4ELN A;  1PWW A;  4H0V A;  4FK7 A;  4XM7 A;  2J3X A;  2WN4 A;  5D1U A;  1OJQ A;  1GIR A;  2J3V A;  4H03 A;  4DV8 A;  5H03 A;  4PKW A;  1PWP A;  2WN5 A;  2WN8 A;  4H0Y A;  4XM6 A;  4PKT A;  2C8C A;  4GF1 A;  1OJZ A;  4PKV A;  4PKR A;  2C8F E;  4XSH B;  1GXY A;  2GWM A;  1JKY A;  4PKS A;  1J7N A;  5GTT A;  2BOV B;  1GXZ A;  2J3Z A;  2GWL A;  2C8G A;  4FML A;  1R45 A;  2C89 A;  2A9K B;  1ZXV A;  4GY2 A;  4WF6 A;  4FXQ A;  3BW8 A;  5H04 A;  1OG3 A;  2A78 B;  2C8H A;  1GIQ A;  1R4B A;  1UZI A;  2C8A A;  2C8B X;  1GY0 A;  5D1T A;  5DZQ A;  4XSG B;  2C8D A;  1QS1 A;  1GZE A;  2WN7 A;  1PWQ A;  1GZF A;  5BWM B;  1OG4 A;  5D1S A;  1YQY A;  4H0T A;  4H0X A;  1PWV A;  4PKQ A;  2C8E E; 
#chains in the Genus database with same CATH topology
 4XM8 A;  1OG1 A;  3NTS A;  4PKU A;  3U0J A;  2WN6 A;  1PWU A;  1G24 A;  4TR5 A;  3BUZ A;  1QS2 A;  4ELN A;  1PWW A;  4H0V A;  4FK7 A;  4XM7 A;  2J3X A;  2WN4 A;  5D1U A;  1OJQ A;  1GIR A;  2J3V A;  4H03 A;  4DV8 A;  5H03 A;  4PKW A;  1PWP A;  2WN5 A;  2WN8 A;  4H0Y A;  4XM6 A;  4PKT A;  2C8C A;  4GF1 A;  1OJZ A;  4PKV A;  4PKR A;  2C8F E;  4XSH B;  1GXY A;  2GWM A;  1JKY A;  4PKS A;  1J7N A;  5GTT A;  2BOV B;  1GXZ A;  2J3Z A;  2GWL A;  2C8G A;  4FML A;  1R45 A;  2C89 A;  2A9K B;  1ZXV A;  4GY2 A;  4WF6 A;  4FXQ A;  3BW8 A;  5H04 A;  1OG3 A;  2A78 B;  2C8H A;  1GIQ A;  1R4B A;  1UZI A;  2C8A A;  2C8B X;  1GY0 A;  5D1T A;  5DZQ A;  4XSG B;  2C8D A;  1QS1 A;  1GZE A;  2WN7 A;  1PWQ A;  1GZF A;  5BWM B;  1OG4 A;  5D1S A;  1YQY A;  4H0T A;  4H0X A;  1PWV A;  4PKQ A;  2C8E E; 
#chains in the Genus database with same CATH homology
 4XM8 A;  1OG1 A;  3NTS A;  4PKU A;  3U0J A;  2WN6 A;  1PWU A;  1G24 A;  4TR5 A;  3BUZ A;  1QS2 A;  4ELN A;  1PWW A;  4H0V A;  4FK7 A;  4XM7 A;  2J3X A;  2WN4 A;  5D1U A;  1OJQ A;  1GIR A;  2J3V A;  4H03 A;  4DV8 A;  5H03 A;  4PKW A;  1PWP A;  2WN5 A;  2WN8 A;  4H0Y A;  4XM6 A;  4PKT A;  2C8C A;  4GF1 A;  1OJZ A;  4PKV A;  4PKR A;  2C8F E;  4XSH B;  1GXY A;  2GWM A;  1JKY A;  4PKS A;  1J7N A;  5GTT A;  2BOV B;  1GXZ A;  2J3Z A;  2GWL A;  2C8G A;  4FML A;  1R45 A;  2C89 A;  2A9K B;  1ZXV A;  4GY2 A;  4WF6 A;  4FXQ A;  3BW8 A;  5H04 A;  1OG3 A;  2A78 B;  2C8H A;  1GIQ A;  1R4B A;  1UZI A;  2C8A A;  2C8B X;  1GY0 A;  5D1T A;  5DZQ A;  4XSG B;  2C8D A;  1QS1 A;  1GZE A;  2WN7 A;  1PWQ A;  1GZF A;  5BWM B;  1OG4 A;  5D1S A;  1YQY A;  4H0T A;  4H0X A;  1PWV A;  4PKQ A;  2C8E E; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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