4Y2EA

Crystal structure of the catalytic domain of human dual-specificity phosphatase 7 (c232s)
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
146
structure length
146
Chain Sequence
AFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDHWSQNLSQFFPEAISFIDEARSKKCGVLVHSLAGISRSVTVTVAYLMQKMNLSLNDAYDFVKRKKSNISPNFNFMGQLLDFERTLGLS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure of human dual-specificity phosphatase 7, a potential cancer drug target.
pubmed doi rcsb
molecule keywords Dual specificity protein phosphatase 7
molecule tags Hydrolase
source organism Homo sapiens
total genus 58
structure length 146
sequence length 146
chains with identical sequence B, C, D
ec nomenclature ec 3.1.3.16: Protein-serine/threonine phosphatase.
pdb deposition date 2015-02-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00782 DSPc Dual specificity phosphatase, catalytic domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.190.10 Alpha Beta Alpha-Beta Complex Protein-Tyrosine Phosphatase; Chain A Protein tyrosine phosphatase superfamily 4y2eA00
1NZ7A 1LARA 3D44A 4AZ1A 2RF6A 3ZM3A 1RPMA 1OEUA 3V0GA 4HJPA 1G4US 3O4SA 1T4JA 3AWEA 2BGEA 4QUMA 1WCHA 1YWFA 1G1FA 2HC1A 4KYQA 4QBEA 2BGDA 2PQ5A 3D1QA 1ONZA 4BJOA 2H4VA 1L8KA 1ZCLA 2JJDA 3A5KA 1ECVA 1PTUA 1Q6TA 2NT2A 4NX8A 1T48A 3B7OA 3F9BA 2A3KA 2QEPA 3QCDA 1FPRA 5LXQB 1KAKA 2BV5A 3BM8A 3S3KA 3QCJA 2PT0A 4NWGA 1Q6PA 5MMZB 2Q05A 2HC2A 2B49A 2Q47A 2C7SA 3MOZA 3SR9A 2VEUA 1D5RA 4H1OA 1Q6JA 3QCKA 1BZCA 1KAVA 3GXHA 1NL9A 3BRHA 2CFVA 3BLTA 2J17A 1OEMX 3QCLA 4OHLA 2I6OA 3M4UA 1NWEA 5GTJA 4GRZA 1Q6MA 1WAXA 2GP0A 2CM7A 2QDCA 4GS0A 3QKPA 1FPZA 4GFUA 4JMJA 1LYVA 2PSZA 2ZMMA 2VEXA 1LQFA 5K23A 3NMEA 4RI4A 4RH5A 2CMBA 2CNGA 4Y2EA 2G6ZA 3N0AA 3QCHA 3SMEA 1C87A 3OMHA 3RZ2A 1OEOX 1YGUA 2OC3A 3ZMPA 4DGPA 3S4EA 3O3LA 1A5YA 2Y96A 1XXPA 4J51A 3D9CA 3EU0A 1EENA 1VHRA 2F71A 4WTYA 2MBCA 2BZLA 1XM2A 1ZC0A 1YTWA 2VEVA 2A8BA 1PTYA 3GXGA 1PA9A 4OHHA 4R0TA 4HRFA 1YPTA 4S0GA 3S3HA 2G59A 1C88A 3QCBA 4GE2A 2HB1A 4QBWA 4YAAA 3QKQA 2DXPA 2I4HA 1ONYA 3I7ZA 2F6ZA 3QCCA 3F41A 5KA3A 1GWZA 2NTAA 3RGOA 3V0IA 2CM2A 2QCJA 2NV5A 4KI9A 2PBNA 1YN9A 3EAXA 1OESA 1NNYA 2B4SA 4D3PA 1L8GA 1AAXA 3D1HA 1BZJA 3ZM2A 5KA0A 5BUGA 4ICZA 4RI5A 4JNBA 2CNIA 3QCFA 2H04A 4RKKA 2AZRA 5K25A 1RXDA 2YDUA 1YTNA 2J16B 4BPCA 3O5XA 4JMKA 1QZ0A 2H4KA 1FQ1A 3MOWA 4KYRA 1G1HA 2IMGA 2NT7A 5KA9A 2NLKA 1G1GA 2HNQA 1C85A 2B4PA 1OETA 1PA1A 4I8NA 5K24A 3D42A 1M3GA 4GWFA 4ZI4A 4D3RA 4NWFA 2I4GA 4B04A 3BLUA 1OEVA 3V0DA 2B07A 3H2XA 2F6FA 2H03A 2CM8A 2QDPA 5KA1A 1GFYA 2FJMA 3CWEA 5KADA 4RHGA 1SUGA 4YR8B 5AWXA 2Y2FA 2B4OA 2QCTA 2C46A 1G7FA 4R0SA 4JBCA 1XBOA 3I80A 3EB1A 3ZMQA 2I75A 1YFOA 1EEOA 1JF7A 1U26A 2FH7A 2PA5A 3EMUA 1YZ4A 2CMCA 4QAHA 4Y14A 5BZXA 1G7GA 1I9SA 2I1YA 1P15A 1U24A 2CM3A 2QBPA 5I6VA 2OOQA 5K9VA 5HDEA 2QBSA 3V0EA 2ESBA 2F6WA 2FJNA 2I5XA 2I6IA 1OHCA 3A5JA 1ZCKA 5KAAA 3CM3A 3ZV2A 1XRIA 2HY3A 3V0JA 2GJTA 2B4UA 1XXVA 4D3QA 3QCEA 2OUDA 3O4UA 1PXHA 2E0TA 5BZZA 2OZ5A 3V0HA 3F99A 2WGPA 3ZM0A 2F46A 4TVVA 2P4DA 1Q6NA 2CNHA 3D1OA 4WOHA 3LJ8A 2M3VA 1U25A 4DGXA 2QBRA 4H34A 4Z6BA 1X24A 2I6MA 4ERCA 2HVLA 4GRYA 4GFVA 2PI7A 5M43A 1QXKA 4IKCA 2GWOA 4ZN5A 1OHDA 1R6HA 1I9TA 4NYHA 4RH9A 1MKPA 1OHEA 2CNEA 3V0FA 4PVGA 3I36A 5IBMA 1YTSA 2H02A 2CMAA 3S3EA 2H4GA 3EZZA 2F70A 3U96A 3RGQA 1T49A 5KABA 2R0BA 3MMJA 1C84A 3AWGA 1C86A 2F6YA 4OHDA 3QCMA 2NZ6A 2SHPA 2I4EA 1PYNA 5EHRA 1V3AA 5KA2A 1BZHA 2I3UA 5KA4A 3QCIA 4RDDA 3O4TA 5K22A 4OHIA 4QUNA 4NNDA 4HJQA 2QBQA 1NO6A 1I57A 3F81A 3RO1A 1Q6SA 2HCMA 4GE6A 2P6XA 4PYHA 1NWLA 1PTTA 3ZM1A 3OLRA 2F6VA 2I6PA 5EHPA 4GE5A 4R30A 2HNPA 1Q1MA 1PTVA 2F6TA 2CJZA 1G4WR 1PH0A 2J16A 3PS5A 2CNFA 5BX1A 5J8RA 3AWFA 1JLNA 5IBSA 3F9AA 4OHEA 4WU2A 2AHSA 3QCNA 2HXPA 1WRMA 3S3FA 2B3OA 3S4OA 2ZN7A 2I42A 4MBBA 2VEWA 2I3RA 5K9WA 4WU3A 1ZZWA 2BIJA 2I6JA 4ZRTA 5KA7A 1C83A 1YGRA 5KA8A 2QDMA 2VEYA 4QAPA 1J4XA 5KACA 3QCGA
chains in the Genus database with same CATH superfamily
1NZ7A 1LARA 3NRSA 3D44A 4AZ1A 4C13A 2RF6A 3ZM3A 1RPMA 1OEUA 3V0GA 4HJPA 1G4US 3O4SA 1T4JA 4QDIA 1FGSA 2BGEA 3AWEA 2JFFA 4QUMA 1WCHA 1YWFA 1G1FA 2HC1A 4KYQA 4QBEA 2BGDA 2PQ5A 3D1QA 1ONZA 4BJOA 2H4VA 1L8KA 1ZCLA 2JJDA 3A5KA 1ECVA 1PTUA 1Q6TA 2NT2A 4NX8A 1T48A 3B7OA 2A3KA 3F9BA 2QEPA 3QCDA 1FPRA 5LXQB 1W78A 1KAKA 2BV5A 3BM8A 3S3KA 3QCJA 2PT0A 4NWGA 1JBVA 1Q6PA 5MMZB 2JFHA 2Q05A 2HC2A 2B49A 2Q47A 2C7SA 3MOZA 1EEHA 2VEUA 3SR9A 1D5RA 4H1OA 1Q6JA 3QCKA 1BZCA 1KAVA 2F00A 3GXHA 1NL9A 3BRHA 2CFVA 3BLTA 2J17A 1OEMX 3QCLA 4OHLA 3HN7A 4QF5A 2I6OA 3M4UA 1NWEA 5GTJA 4GRZA 1Q6MA 1WAXA 2GP0A 2CM7A 5A5FA 2QDCA 4GS0A 3QKPA 1FPZA 4GFUA 4JMJA 1LYVA 2PSZA 2ZMMA 2VEXA 1LQFA 5K23A 3NMEA 4UAGA 4RI4A 1E0DA 4RH5A 2CMBA 2CNGA 4Y2EA 2G6ZA 3N0AA 3QCHA 3SMEA 1C87A 3OMHA 3RZ2A 2Y1OA 1OEOX 1YGUA 2OC3A 3ZMPA 4DGPA 3S4EA 3O3LA 1A5YA 2Y96A 1XXPA 4J51A 3D9CA 2XPCA 3EU0A 1EENA 1VHRA 2F71A 4WTYA 3QCZA 1E8CA 2MBCA 2BZLA 1XM2A 1ZC0A 1YTWA 2VEVA 1PTYA 3GXGA 1PA9A 4OHHA 4R0TA 4HRFA 1UAGA 1YPTA 4S0GA 3S3HA 2G59A 1C88A 3QCBA 4GE2A 2HB1A 4QBWA 4YAAA 1JBWA 3QKQA 2DXPA 2VTDA 2I4HA 2UAGA 1ONYA 3I7ZA 2F6ZA 3QCCA 3F41A 5KA3A 1GWZA 2NTAA 3RGOA 3V0IA 2CM2A 2QCJA 2NV5A 4KI9A 2PBNA 1YN9A 3LK7A 3EAXA 1OESA 1NNYA 2B4SA 4D3PA 1L8GA 1AAXA 3D1HA 4C12A 1BZJA 3ZM2A 5KA0A 5BUGA 4ICZA 4RI5A 3ZM5A 4JNBA 2CNIA 3QCFA 2H04A 4RKKA 2AZRA 5K25A 2GC5A 1RXDA 2YDUA 1YTNA 4CVLA 2J16B 4BPCA 3O5XA 4JMKA 1QZ0A 2H4KA 1FQ1A 3MOWA 4KYRA 2AM1A 2GCBA 1G1HA 2IMGA 2NT7A 5KA9A 2NLKA 1G1GA 2HNQA 1C85A 2B4PA 1OETA 3N2AA 1PA1A 4I8NA 5K24A 4CVMA 3D42A 1M3GA 4GWFA 4ZI4A 3MVNA 4D3RA 4NWFA 2I4GA 4B04A 3BLUA 1OEVA 3V0DA 2B07A 2GC6A 3H2XA 2F6FA 2H03A 2CM8A 2QDPA 2Y66A 5KA1A 1GFYA 2FJMA 3CWEA 5KADA 4RHGA 1SUGA 2WJPA 4YR8B 5AWXA 2Y2FA 2B4OA 2UUOA 2QCTA 2C46A 1G7FA 4R0SA 4JBCA 1XBOA 3I80A 3EB1A 3ZMQA 2I75A 4ZIYA 1YFOA 1EEOA 1JF7A 1U26A 2FH7A 2PA5A 3EMUA 1P3DA 1YZ4A 2CMCA 4QAHA 4Y14A 5BZXA 1G7GA 1GQYA 1I9SA 2Y67A 2I1YA 1P15A 1U24A 2CM3A 2QBPA 5I6VA 2OOQA 5K9VA 5HDEA 2QBSA 3V0EA 2ESBA 2F6WA 2FJNA 2I5XA 2I6IA 2JFGA 2VOSA 1OHCA 3A5JA 1ZCKA 5KAAA 3CM3A 3ZV2A 1XRIA 2HY3A 3V0JA 1W7KA 2UUPA 2GJTA 5A5EA 2B4UA 1P31A 1XXVA 4HV4A 4D3QA 3QCEA 2OUDA 3O4UA 1PXHA 2E0TA 5BZZA 2OZ5A 3V0HA 3F99A 2WGPA 3ZM0A 2F46A 4TVVA 2P4DA 1Q6NA 2CNHA 3D1OA 4WOHA 3LJ8A 2M3VA 1U25A 4DGXA 4BUCA 2QBRA 2XJAA 4H34A 4Z6BA 1X24A 2I6MA 4ERCA 2HVLA 4GRYA 4GFVA 2PI7A 5M43A 1QXKA 4IKCA 2VTEA 2GWOA 4ZN5A 1OHDA 1R6HA 1I9TA 4NYHA 4RH9A 1MKPA 3ZM6A 1OHEA 2CNEA 3V0FA 4PVGA 3I36A 5IBMA 1YTSA 2H02A 2CMAA 3S3EA 2H4GA 3EZZA 2F70A 3U96A 4BUBA 3RGQA 1O5ZA 1T49A 5KABA 2R0BA 2AM2A 3MMJA 1C84A 3AWGA 1C86A 2F6YA 4OHDA 3QCMA 3QCGA 2NZ6A 2SHPA 2I4EA 1PYNA 5EHRA 1V3AA 3UAGA 5KA2A 1BZHA 2I3UA 5KA4A 3QCIA 4RDDA 3O4TA 5K22A 4OHIA 3PYZA 4QUNA 4NNDA 4HJQA 2QBQA 1NO6A 1I57A 3F81A 3RO1A 1Q6SA 2HCMA 2VORA 4GE6A 2P6XA 2WTZA 4PYHA 1GG4A 1NWLA 1J6UA 1PTTA 3ZM1A 3OLRA 2F6VA 2Y68A 2I6PA 5EHPA 4GE5A 4R30A 2HNPA 1Q1MA 1PTVA 2F6TA 2CJZA 1G4WR 1PH0A 2J16A 3PS5A 2CNFA 4CVKA 2GCAA 5BX1A 5J8RA 3AWFA 1JLNA 5IBSA 3F9AA 4OHEA 4WU2A 2AHSA 2X5OA 3QCNA 3ZL8A 2HXPA 1WRMA 3S3FA 2B3OA 3S4OA 2ZN7A 2I42A 4MBBA 2VEWA 2I3RA 5K9WA 4WU3A 1ZZWA 2BIJA 2I6JA 4ZRTA 5KA7A 1C83A 1YGRA 5KA8A 1GQQA 2QDMA 2VEYA 4QAPA 1J4XA 5KACA 2A8BA
chains in the Genus database with same CATH topology
1NZ7A 1LARA 3D44A 4AZ1A 2RF6A 3ZM3A 1RPMA 1OEUA 3V0GA 4HJPA 1G4US 3O4SA 1T4JA 3AWEA 2BGEA 4QUMA 1WCHA 1YWFA 1G1FA 2HC1A 4KYQA 4QBEA 2BGDA 2PQ5A 3D1QA 1ONZA 4BJOA 2H4VA 1L8KA 1ZCLA 2JJDA 3A5KA 1ECVA 1PTUA 1Q6TA 2NT2A 4NX8A 1T48A 3B7OA 3F9BA 2A3KA 2QEPA 3QCDA 1FPRA 5LXQB 1KAKA 2BV5A 3BM8A 3S3KA 3QCJA 2PT0A 4NWGA 1Q6PA 5MMZB 2Q05A 2HC2A 2B49A 2Q47A 2C7SA 3MOZA 3SR9A 2VEUA 1D5RA 4H1OA 1Q6JA 3QCKA 1BZCA 1KAVA 3GXHA 1NL9A 3BRHA 2CFVA 3BLTA 2J17A 1OEMX 3QCLA 4OHLA 2I6OA 3M4UA 1NWEA 5GTJA 4GRZA 1Q6MA 1WAXA 2GP0A 2CM7A 2QDCA 4GS0A 3QKPA 1FPZA 4GFUA 4JMJA 1LYVA 2PSZA 2ZMMA 2VEXA 1LQFA 5K23A 3NMEA 4RI4A 4RH5A 2CMBA 2CNGA 4Y2EA 2G6ZA 3N0AA 3QCHA 3SMEA 1C87A 3OMHA 3RZ2A 1OEOX 1YGUA 2OC3A 3ZMPA 4DGPA 3S4EA 3O3LA 1A5YA 2Y96A 1XXPA 4J51A 3D9CA 3EU0A 1EENA 1VHRA 2F71A 4WTYA 2MBCA 2BZLA 1XM2A 1ZC0A 1YTWA 2VEVA 2A8BA 1PTYA 3GXGA 1PA9A 4OHHA 4R0TA 4HRFA 1YPTA 4S0GA 3S3HA 2G59A 1C88A 3QCBA 4GE2A 2HB1A 4QBWA 4YAAA 3QKQA 2DXPA 2I4HA 1ONYA 3I7ZA 2F6ZA 3QCCA 3F41A 5KA3A 1GWZA 2NTAA 3RGOA 3V0IA 2CM2A 2QCJA 2NV5A 4KI9A 2PBNA 1YN9A 3EAXA 1OESA 1NNYA 2B4SA 4D3PA 1L8GA 1AAXA 3D1HA 1BZJA 3ZM2A 5KA0A 5BUGA 4ICZA 4RI5A 4JNBA 2CNIA 3QCFA 2H04A 4RKKA 2AZRA 5K25A 1RXDA 2YDUA 1YTNA 2J16B 4BPCA 3O5XA 4JMKA 1QZ0A 2H4KA 1FQ1A 3MOWA 4KYRA 1G1HA 2IMGA 2NT7A 5KA9A 2NLKA 1G1GA 2HNQA 1C85A 2B4PA 1OETA 1PA1A 4I8NA 5K24A 3D42A 1M3GA 4GWFA 4ZI4A 4D3RA 4NWFA 2I4GA 4B04A 3BLUA 1OEVA 3V0DA 2B07A 3H2XA 2F6FA 2H03A 2CM8A 2QDPA 5KA1A 1GFYA 2FJMA 3CWEA 5KADA 4RHGA 1SUGA 4YR8B 5AWXA 2Y2FA 2B4OA 2QCTA 2C46A 1G7FA 4R0SA 4JBCA 1XBOA 3I80A 3EB1A 3ZMQA 2I75A 1YFOA 1EEOA 1JF7A 1U26A 2FH7A 2PA5A 3EMUA 1YZ4A 2CMCA 4QAHA 4Y14A 5BZXA 1G7GA 1I9SA 2I1YA 1P15A 1U24A 2CM3A 2QBPA 5I6VA 2OOQA 5K9VA 5HDEA 2QBSA 3V0EA 2ESBA 2F6WA 2FJNA 2I5XA 2I6IA 1OHCA 3A5JA 1ZCKA 5KAAA 3CM3A 3ZV2A 1XRIA 2HY3A 3V0JA 2GJTA 2B4UA 1XXVA 4D3QA 3QCEA 2OUDA 3O4UA 1PXHA 2E0TA 5BZZA 2OZ5A 3V0HA 3F99A 2WGPA 3ZM0A 2F46A 4TVVA 2P4DA 1Q6NA 2CNHA 3D1OA 4WOHA 3LJ8A 2M3VA 1U25A 4DGXA 2QBRA 4H34A 4Z6BA 1X24A 2I6MA 4ERCA 2HVLA 4GRYA 4GFVA 2PI7A 5M43A 1QXKA 4IKCA 2GWOA 4ZN5A 1OHDA 1R6HA 1I9TA 4NYHA 4RH9A 1MKPA 1OHEA 2CNEA 3V0FA 4PVGA 3I36A 5IBMA 1YTSA 2H02A 2CMAA 3S3EA 2H4GA 3EZZA 2F70A 3U96A 3RGQA 1T49A 5KABA 2R0BA 3MMJA 1C84A 3AWGA 1C86A 2F6YA 4OHDA 3QCMA 2NZ6A 2SHPA 2I4EA 1PYNA 5EHRA 1V3AA 5KA2A 1BZHA 2I3UA 5KA4A 3QCIA 4RDDA 3O4TA 5K22A 4OHIA 4QUNA 4NNDA 4HJQA 2QBQA 1NO6A 1I57A 3F81A 3RO1A 1Q6SA 2HCMA 4GE6A 2P6XA 4PYHA 1NWLA 1PTTA 3ZM1A 3OLRA 2F6VA 2I6PA 5EHPA 4GE5A 4R30A 2HNPA 1Q1MA 1PTVA 2F6TA 2CJZA 1G4WR 1PH0A 2J16A 3PS5A 2CNFA 5BX1A 5J8RA 3AWFA 1JLNA 5IBSA 3F9AA 4OHEA 4WU2A 2AHSA 3QCNA 2HXPA 1WRMA 3S3FA 2B3OA 3S4OA 2ZN7A 2I42A 4MBBA 2VEWA 2I3RA 5K9WA 4WU3A 1ZZWA 2BIJA 2I6JA 4ZRTA 5KA7A 1C83A 1YGRA 5KA8A 2QDMA 2VEYA 4QAPA 1J4XA 5KACA 3QCGA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1NZ7 A;  1LAR A;  3D44 A;  4AZ1 A;  2RF6 A;  3ZM3 A;  1RPM A;  1OEU A;  3V0G A;  4HJP A;  1G4U S;  3O4S A;  1T4J A;  3AWE A;  2BGE A;  4QUM A;  1WCH A;  1YWF A;  1G1F A;  2HC1 A;  4KYQ A;  4QBE A;  2BGD A;  2PQ5 A;  3D1Q A;  1ONZ A;  4BJO A;  2H4V A;  1L8K A;  1ZCL A;  2JJD A;  3A5K A;  1ECV A;  1PTU A;  1Q6T A;  2NT2 A;  4NX8 A;  1T48 A;  3B7O A;  3F9B A;  2A3K A;  2QEP A;  3QCD A;  1FPR A;  5LXQ B;  1KAK A;  2BV5 A;  3BM8 A;  3S3K A;  3QCJ A;  2PT0 A;  4NWG A;  1Q6P A;  5MMZ B;  2Q05 A;  2HC2 A;  2B49 A;  2Q47 A;  2C7S A;  3MOZ A;  3SR9 A;  2VEU A;  1D5R A;  4H1O A;  1Q6J A;  3QCK A;  1BZC A;  1KAV A;  3GXH A;  1NL9 A;  3BRH A;  2CFV A;  3BLT A;  2J17 A;  1OEM X;  3QCL A;  4OHL A;  2I6O A;  3M4U A;  1NWE A;  5GTJ A;  4GRZ A;  1Q6M A;  1WAX A;  2GP0 A;  2CM7 A;  2QDC A;  4GS0 A;  3QKP A;  1FPZ A;  4GFU A;  4JMJ A;  1LYV A;  2PSZ A;  2ZMM A;  2VEX A;  1LQF A;  5K23 A;  3NME A;  4RI4 A;  4RH5 A;  2CMB A;  2CNG A;  4Y2E A;  2G6Z A;  3N0A A;  3QCH A;  3SME A;  1C87 A;  3OMH A;  3RZ2 A;  1OEO X;  1YGU A;  2OC3 A;  3ZMP A;  4DGP A;  3S4E A;  3O3L A;  1A5Y A;  2Y96 A;  1XXP A;  4J51 A;  3D9C A;  3EU0 A;  1EEN A;  1VHR A;  2F71 A;  4WTY A;  2MBC A;  2BZL A;  1XM2 A;  1ZC0 A;  1YTW A;  2VEV A;  2A8B A;  1PTY A;  3GXG A;  1PA9 A;  4OHH A;  4R0T A;  4HRF A;  1YPT A;  4S0G A;  3S3H A;  2G59 A;  1C88 A;  3QCB A;  4GE2 A;  2HB1 A;  4QBW A;  4YAA A;  3QKQ A;  2DXP A;  2I4H A;  1ONY A;  3I7Z A;  2F6Z A;  3QCC A;  3F41 A;  5KA3 A;  1GWZ A;  2NTA A;  3RGO A;  3V0I A;  2CM2 A;  2QCJ A;  2NV5 A;  4KI9 A;  2PBN A;  1YN9 A;  3EAX A;  1OES A;  1NNY A;  2B4S A;  4D3P A;  1L8G A;  1AAX A;  3D1H A;  1BZJ A;  3ZM2 A;  5KA0 A;  5BUG A;  4ICZ A;  4RI5 A;  4JNB A;  2CNI A;  3QCF A;  2H04 A;  4RKK A;  2AZR A;  5K25 A;  1RXD A;  2YDU A;  1YTN A;  2J16 B;  4BPC A;  3O5X A;  4JMK A;  1QZ0 A;  2H4K A;  1FQ1 A;  3MOW A;  4KYR A;  1G1H A;  2IMG A;  2NT7 A;  5KA9 A;  2NLK A;  1G1G A;  2HNQ A;  1C85 A;  2B4P A;  1OET A;  1PA1 A;  4I8N A;  5K24 A;  3D42 A;  1M3G A;  4GWF A;  4ZI4 A;  4D3R A;  4NWF A;  2I4G A;  4B04 A;  3BLU A;  1OEV A;  3V0D A;  2B07 A;  3H2X A;  2F6F A;  2H03 A;  2CM8 A;  2QDP A;  5KA1 A;  1GFY A;  2FJM A;  3CWE A;  5KAD A;  4RHG A;  1SUG A;  4YR8 B;  5AWX A;  2Y2F A;  2B4O A;  2QCT A;  2C46 A;  1G7F A;  4R0S A;  4JBC A;  1XBO A;  3I80 A;  3EB1 A;  3ZMQ A;  2I75 A;  1YFO A;  1EEO A;  1JF7 A;  1U26 A;  2FH7 A;  2PA5 A;  3EMU A;  1YZ4 A;  2CMC A;  4QAH A;  4Y14 A;  5BZX A;  1G7G A;  1I9S A;  2I1Y A;  1P15 A;  1U24 A;  2CM3 A;  2QBP A;  5I6V A;  2OOQ A;  5K9V A;  5HDE A;  2QBS A;  3V0E A;  2ESB A;  2F6W A;  2FJN A;  2I5X A;  2I6I A;  1OHC A;  3A5J A;  1ZCK A;  5KAA A;  3CM3 A;  3ZV2 A;  1XRI A;  2HY3 A;  3V0J A;  2GJT A;  2B4U A;  1XXV A;  4D3Q A;  3QCE A;  2OUD A;  3O4U A;  1PXH A;  2E0T A;  5BZZ A;  2OZ5 A;  3V0H A;  3F99 A;  2WGP A;  3ZM0 A;  2F46 A;  4TVV A;  2P4D A;  1Q6N A;  2CNH A;  3D1O A;  4WOH A;  3LJ8 A;  2M3V A;  1U25 A;  4DGX A;  2QBR A;  4H34 A;  4Z6B A;  1X24 A;  2I6M A;  4ERC A;  2HVL A;  4GRY A;  4GFV A;  2PI7 A;  5M43 A;  1QXK A;  4IKC A;  2GWO A;  4ZN5 A;  1OHD A;  1R6H A;  1I9T A;  4NYH A;  4RH9 A;  1MKP A;  1OHE A;  2CNE A;  3V0F A;  4PVG A;  3I36 A;  5IBM A;  1YTS A;  2H02 A;  2CMA A;  3S3E A;  2H4G A;  3EZZ A;  2F70 A;  3U96 A;  3RGQ A;  1T49 A;  5KAB A;  2R0B A;  3MMJ A;  1C84 A;  3AWG A;  1C86 A;  2F6Y A;  4OHD A;  3QCM A;  2NZ6 A;  2SHP A;  2I4E A;  1PYN A;  5EHR A;  1V3A A;  5KA2 A;  1BZH A;  2I3U A;  5KA4 A;  3QCI A;  4RDD A;  3O4T A;  5K22 A;  4OHI A;  4QUN A;  4NND A;  4HJQ A;  2QBQ A;  1NO6 A;  1I57 A;  3F81 A;  3RO1 A;  1Q6S A;  2HCM A;  4GE6 A;  2P6X A;  4PYH A;  1NWL A;  1PTT A;  3ZM1 A;  3OLR A;  2F6V A;  2I6P A;  5EHP A;  4GE5 A;  4R30 A;  2HNP A;  1Q1M A;  1PTV A;  2F6T A;  2CJZ A;  1G4W R;  1PH0 A;  2J16 A;  3PS5 A;  2CNF A;  5BX1 A;  5J8R A;  3AWF A;  1JLN A;  5IBS A;  3F9A A;  4OHE A;  4WU2 A;  2AHS A;  3QCN A;  2HXP A;  1WRM A;  3S3F A;  2B3O A;  3S4O A;  2ZN7 A;  2I42 A;  4MBB A;  2VEW A;  2I3R A;  5K9W A;  4WU3 A;  1ZZW A;  2BIJ A;  2I6J A;  4ZRT A;  5KA7 A;  1C83 A;  1YGR A;  5KA8 A;  2QDM A;  2VEY A;  4QAP A;  1J4X A;  5KAC A;  3QCG A; 
#chains in the Genus database with same CATH topology
 1NZ7 A;  1LAR A;  3NRS A;  3D44 A;  4AZ1 A;  4C13 A;  2RF6 A;  3ZM3 A;  1RPM A;  1OEU A;  3V0G A;  4HJP A;  1G4U S;  3O4S A;  1T4J A;  4QDI A;  1FGS A;  2BGE A;  3AWE A;  2JFF A;  4QUM A;  1WCH A;  1YWF A;  1G1F A;  2HC1 A;  4KYQ A;  4QBE A;  2BGD A;  2PQ5 A;  3D1Q A;  1ONZ A;  4BJO A;  2H4V A;  1L8K A;  1ZCL A;  2JJD A;  3A5K A;  1ECV A;  1PTU A;  1Q6T A;  2NT2 A;  4NX8 A;  1T48 A;  3B7O A;  2A3K A;  3F9B A;  2QEP A;  3QCD A;  1FPR A;  5LXQ B;  1W78 A;  1KAK A;  2BV5 A;  3BM8 A;  3S3K A;  3QCJ A;  2PT0 A;  4NWG A;  1JBV A;  1Q6P A;  5MMZ B;  2JFH A;  2Q05 A;  2HC2 A;  2B49 A;  2Q47 A;  2C7S A;  3MOZ A;  1EEH A;  2VEU A;  3SR9 A;  1D5R A;  4H1O A;  1Q6J A;  3QCK A;  1BZC A;  1KAV A;  2F00 A;  3GXH A;  1NL9 A;  3BRH A;  2CFV A;  3BLT A;  2J17 A;  1OEM X;  3QCL A;  4OHL A;  3HN7 A;  4QF5 A;  2I6O A;  3M4U A;  1NWE A;  5GTJ A;  4GRZ A;  1Q6M A;  1WAX A;  2GP0 A;  2CM7 A;  5A5F A;  2QDC A;  4GS0 A;  3QKP A;  1FPZ A;  4GFU A;  4JMJ A;  1LYV A;  2PSZ A;  2ZMM A;  2VEX A;  1LQF A;  5K23 A;  3NME A;  4UAG A;  4RI4 A;  1E0D A;  4RH5 A;  2CMB A;  2CNG A;  4Y2E A;  2G6Z A;  3N0A A;  3QCH A;  3SME A;  1C87 A;  3OMH A;  3RZ2 A;  2Y1O A;  1OEO X;  1YGU A;  2OC3 A;  3ZMP A;  4DGP A;  3S4E A;  3O3L A;  1A5Y A;  2Y96 A;  1XXP A;  4J51 A;  3D9C A;  2XPC A;  3EU0 A;  1EEN A;  1VHR A;  2F71 A;  4WTY A;  3QCZ A;  1E8C A;  2MBC A;  2BZL A;  1XM2 A;  1ZC0 A;  1YTW A;  2VEV A;  1PTY A;  3GXG A;  1PA9 A;  4OHH A;  4R0T A;  4HRF A;  1UAG A;  1YPT A;  4S0G A;  3S3H A;  2G59 A;  1C88 A;  3QCB A;  4GE2 A;  2HB1 A;  4QBW A;  4YAA A;  1JBW A;  3QKQ A;  2DXP A;  2VTD A;  2I4H A;  2UAG A;  1ONY A;  3I7Z A;  2F6Z A;  3QCC A;  3F41 A;  5KA3 A;  1GWZ A;  2NTA A;  3RGO A;  3V0I A;  2CM2 A;  2QCJ A;  2NV5 A;  4KI9 A;  2PBN A;  1YN9 A;  3LK7 A;  3EAX A;  1OES A;  1NNY A;  2B4S A;  4D3P A;  1L8G A;  1AAX A;  3D1H A;  4C12 A;  1BZJ A;  3ZM2 A;  5KA0 A;  5BUG A;  4ICZ A;  4RI5 A;  3ZM5 A;  4JNB A;  2CNI A;  3QCF A;  2H04 A;  4RKK A;  2AZR A;  5K25 A;  2GC5 A;  1RXD A;  2YDU A;  1YTN A;  4CVL A;  2J16 B;  4BPC A;  3O5X A;  4JMK A;  1QZ0 A;  2H4K A;  1FQ1 A;  3MOW A;  4KYR A;  2AM1 A;  2GCB A;  1G1H A;  2IMG A;  2NT7 A;  5KA9 A;  2NLK A;  1G1G A;  2HNQ A;  1C85 A;  2B4P A;  1OET A;  3N2A A;  1PA1 A;  4I8N A;  5K24 A;  4CVM A;  3D42 A;  1M3G A;  4GWF A;  4ZI4 A;  3MVN A;  4D3R A;  4NWF A;  2I4G A;  4B04 A;  3BLU A;  1OEV A;  3V0D A;  2B07 A;  2GC6 A;  3H2X A;  2F6F A;  2H03 A;  2CM8 A;  2QDP A;  2Y66 A;  5KA1 A;  1GFY A;  2FJM A;  3CWE A;  5KAD A;  4RHG A;  1SUG A;  2WJP A;  4YR8 B;  5AWX A;  2Y2F A;  2B4O A;  2UUO A;  2QCT A;  2C46 A;  1G7F A;  4R0S A;  4JBC A;  1XBO A;  3I80 A;  3EB1 A;  3ZMQ A;  2I75 A;  4ZIY A;  1YFO A;  1EEO A;  1JF7 A;  1U26 A;  2FH7 A;  2PA5 A;  3EMU A;  1P3D A;  1YZ4 A;  2CMC A;  4QAH A;  4Y14 A;  5BZX A;  1G7G A;  1GQY A;  1I9S A;  2Y67 A;  2I1Y A;  1P15 A;  1U24 A;  2CM3 A;  2QBP A;  5I6V A;  2OOQ A;  5K9V A;  5HDE A;  2QBS A;  3V0E A;  2ESB A;  2F6W A;  2FJN A;  2I5X A;  2I6I A;  2JFG A;  2VOS A;  1OHC A;  3A5J A;  1ZCK A;  5KAA A;  3CM3 A;  3ZV2 A;  1XRI A;  2HY3 A;  3V0J A;  1W7K A;  2UUP A;  2GJT A;  5A5E A;  2B4U A;  1P31 A;  1XXV A;  4HV4 A;  4D3Q A;  3QCE A;  2OUD A;  3O4U A;  1PXH A;  2E0T A;  5BZZ A;  2OZ5 A;  3V0H A;  3F99 A;  2WGP A;  3ZM0 A;  2F46 A;  4TVV A;  2P4D A;  1Q6N A;  2CNH A;  3D1O A;  4WOH A;  3LJ8 A;  2M3V A;  1U25 A;  4DGX A;  4BUC A;  2QBR A;  2XJA A;  4H34 A;  4Z6B A;  1X24 A;  2I6M A;  4ERC A;  2HVL A;  4GRY A;  4GFV A;  2PI7 A;  5M43 A;  1QXK A;  4IKC A;  2VTE A;  2GWO A;  4ZN5 A;  1OHD A;  1R6H A;  1I9T A;  4NYH A;  4RH9 A;  1MKP A;  3ZM6 A;  1OHE A;  2CNE A;  3V0F A;  4PVG A;  3I36 A;  5IBM A;  1YTS A;  2H02 A;  2CMA A;  3S3E A;  2H4G A;  3EZZ A;  2F70 A;  3U96 A;  4BUB A;  3RGQ A;  1O5Z A;  1T49 A;  5KAB A;  2R0B A;  2AM2 A;  3MMJ A;  1C84 A;  3AWG A;  1C86 A;  2F6Y A;  4OHD A;  3QCM A;  3QCG A;  2NZ6 A;  2SHP A;  2I4E A;  1PYN A;  5EHR A;  1V3A A;  3UAG A;  5KA2 A;  1BZH A;  2I3U A;  5KA4 A;  3QCI A;  4RDD A;  3O4T A;  5K22 A;  4OHI A;  3PYZ A;  4QUN A;  4NND A;  4HJQ A;  2QBQ A;  1NO6 A;  1I57 A;  3F81 A;  3RO1 A;  1Q6S A;  2HCM A;  2VOR A;  4GE6 A;  2P6X A;  2WTZ A;  4PYH A;  1GG4 A;  1NWL A;  1J6U A;  1PTT A;  3ZM1 A;  3OLR A;  2F6V A;  2Y68 A;  2I6P A;  5EHP A;  4GE5 A;  4R30 A;  2HNP A;  1Q1M A;  1PTV A;  2F6T A;  2CJZ A;  1G4W R;  1PH0 A;  2J16 A;  3PS5 A;  2CNF A;  4CVK A;  2GCA A;  5BX1 A;  5J8R A;  3AWF A;  1JLN A;  5IBS A;  3F9A A;  4OHE A;  4WU2 A;  2AHS A;  2X5O A;  3QCN A;  3ZL8 A;  2HXP A;  1WRM A;  3S3F A;  2B3O A;  3S4O A;  2ZN7 A;  2I42 A;  4MBB A;  2VEW A;  2I3R A;  5K9W A;  4WU3 A;  1ZZW A;  2BIJ A;  2I6J A;  4ZRT A;  5KA7 A;  1C83 A;  1YGR A;  5KA8 A;  1GQQ A;  2QDM A;  2VEY A;  4QAP A;  1J4X A;  5KAC A;  2A8B A; 
#chains in the Genus database with same CATH homology
 1NZ7 A;  1LAR A;  3D44 A;  4AZ1 A;  2RF6 A;  3ZM3 A;  1RPM A;  1OEU A;  3V0G A;  4HJP A;  1G4U S;  3O4S A;  1T4J A;  3AWE A;  2BGE A;  4QUM A;  1WCH A;  1YWF A;  1G1F A;  2HC1 A;  4KYQ A;  4QBE A;  2BGD A;  2PQ5 A;  3D1Q A;  1ONZ A;  4BJO A;  2H4V A;  1L8K A;  1ZCL A;  2JJD A;  3A5K A;  1ECV A;  1PTU A;  1Q6T A;  2NT2 A;  4NX8 A;  1T48 A;  3B7O A;  3F9B A;  2A3K A;  2QEP A;  3QCD A;  1FPR A;  5LXQ B;  1KAK A;  2BV5 A;  3BM8 A;  3S3K A;  3QCJ A;  2PT0 A;  4NWG A;  1Q6P A;  5MMZ B;  2Q05 A;  2HC2 A;  2B49 A;  2Q47 A;  2C7S A;  3MOZ A;  3SR9 A;  2VEU A;  1D5R A;  4H1O A;  1Q6J A;  3QCK A;  1BZC A;  1KAV A;  3GXH A;  1NL9 A;  3BRH A;  2CFV A;  3BLT A;  2J17 A;  1OEM X;  3QCL A;  4OHL A;  2I6O A;  3M4U A;  1NWE A;  5GTJ A;  4GRZ A;  1Q6M A;  1WAX A;  2GP0 A;  2CM7 A;  2QDC A;  4GS0 A;  3QKP A;  1FPZ A;  4GFU A;  4JMJ A;  1LYV A;  2PSZ A;  2ZMM A;  2VEX A;  1LQF A;  5K23 A;  3NME A;  4RI4 A;  4RH5 A;  2CMB A;  2CNG A;  4Y2E A;  2G6Z A;  3N0A A;  3QCH A;  3SME A;  1C87 A;  3OMH A;  3RZ2 A;  1OEO X;  1YGU A;  2OC3 A;  3ZMP A;  4DGP A;  3S4E A;  3O3L A;  1A5Y A;  2Y96 A;  1XXP A;  4J51 A;  3D9C A;  3EU0 A;  1EEN A;  1VHR A;  2F71 A;  4WTY A;  2MBC A;  2BZL A;  1XM2 A;  1ZC0 A;  1YTW A;  2VEV A;  2A8B A;  1PTY A;  3GXG A;  1PA9 A;  4OHH A;  4R0T A;  4HRF A;  1YPT A;  4S0G A;  3S3H A;  2G59 A;  1C88 A;  3QCB A;  4GE2 A;  2HB1 A;  4QBW A;  4YAA A;  3QKQ A;  2DXP A;  2I4H A;  1ONY A;  3I7Z A;  2F6Z A;  3QCC A;  3F41 A;  5KA3 A;  1GWZ A;  2NTA A;  3RGO A;  3V0I A;  2CM2 A;  2QCJ A;  2NV5 A;  4KI9 A;  2PBN A;  1YN9 A;  3EAX A;  1OES A;  1NNY A;  2B4S A;  4D3P A;  1L8G A;  1AAX A;  3D1H A;  1BZJ A;  3ZM2 A;  5KA0 A;  5BUG A;  4ICZ A;  4RI5 A;  4JNB A;  2CNI A;  3QCF A;  2H04 A;  4RKK A;  2AZR A;  5K25 A;  1RXD A;  2YDU A;  1YTN A;  2J16 B;  4BPC A;  3O5X A;  4JMK A;  1QZ0 A;  2H4K A;  1FQ1 A;  3MOW A;  4KYR A;  1G1H A;  2IMG A;  2NT7 A;  5KA9 A;  2NLK A;  1G1G A;  2HNQ A;  1C85 A;  2B4P A;  1OET A;  1PA1 A;  4I8N A;  5K24 A;  3D42 A;  1M3G A;  4GWF A;  4ZI4 A;  4D3R A;  4NWF A;  2I4G A;  4B04 A;  3BLU A;  1OEV A;  3V0D A;  2B07 A;  3H2X A;  2F6F A;  2H03 A;  2CM8 A;  2QDP A;  5KA1 A;  1GFY A;  2FJM A;  3CWE A;  5KAD A;  4RHG A;  1SUG A;  4YR8 B;  5AWX A;  2Y2F A;  2B4O A;  2QCT A;  2C46 A;  1G7F A;  4R0S A;  4JBC A;  1XBO A;  3I80 A;  3EB1 A;  3ZMQ A;  2I75 A;  1YFO A;  1EEO A;  1JF7 A;  1U26 A;  2FH7 A;  2PA5 A;  3EMU A;  1YZ4 A;  2CMC A;  4QAH A;  4Y14 A;  5BZX A;  1G7G A;  1I9S A;  2I1Y A;  1P15 A;  1U24 A;  2CM3 A;  2QBP A;  5I6V A;  2OOQ A;  5K9V A;  5HDE A;  2QBS A;  3V0E A;  2ESB A;  2F6W A;  2FJN A;  2I5X A;  2I6I A;  1OHC A;  3A5J A;  1ZCK A;  5KAA A;  3CM3 A;  3ZV2 A;  1XRI A;  2HY3 A;  3V0J A;  2GJT A;  2B4U A;  1XXV A;  4D3Q A;  3QCE A;  2OUD A;  3O4U A;  1PXH A;  2E0T A;  5BZZ A;  2OZ5 A;  3V0H A;  3F99 A;  2WGP A;  3ZM0 A;  2F46 A;  4TVV A;  2P4D A;  1Q6N A;  2CNH A;  3D1O A;  4WOH A;  3LJ8 A;  2M3V A;  1U25 A;  4DGX A;  2QBR A;  4H34 A;  4Z6B A;  1X24 A;  2I6M A;  4ERC A;  2HVL A;  4GRY A;  4GFV A;  2PI7 A;  5M43 A;  1QXK A;  4IKC A;  2GWO A;  4ZN5 A;  1OHD A;  1R6H A;  1I9T A;  4NYH A;  4RH9 A;  1MKP A;  1OHE A;  2CNE A;  3V0F A;  4PVG A;  3I36 A;  5IBM A;  1YTS A;  2H02 A;  2CMA A;  3S3E A;  2H4G A;  3EZZ A;  2F70 A;  3U96 A;  3RGQ A;  1T49 A;  5KAB A;  2R0B A;  3MMJ A;  1C84 A;  3AWG A;  1C86 A;  2F6Y A;  4OHD A;  3QCM A;  2NZ6 A;  2SHP A;  2I4E A;  1PYN A;  5EHR A;  1V3A A;  5KA2 A;  1BZH A;  2I3U A;  5KA4 A;  3QCI A;  4RDD A;  3O4T A;  5K22 A;  4OHI A;  4QUN A;  4NND A;  4HJQ A;  2QBQ A;  1NO6 A;  1I57 A;  3F81 A;  3RO1 A;  1Q6S A;  2HCM A;  4GE6 A;  2P6X A;  4PYH A;  1NWL A;  1PTT A;  3ZM1 A;  3OLR A;  2F6V A;  2I6P A;  5EHP A;  4GE5 A;  4R30 A;  2HNP A;  1Q1M A;  1PTV A;  2F6T A;  2CJZ A;  1G4W R;  1PH0 A;  2J16 A;  3PS5 A;  2CNF A;  5BX1 A;  5J8R A;  3AWF A;  1JLN A;  5IBS A;  3F9A A;  4OHE A;  4WU2 A;  2AHS A;  3QCN A;  2HXP A;  1WRM A;  3S3F A;  2B3O A;  3S4O A;  2ZN7 A;  2I42 A;  4MBB A;  2VEW A;  2I3R A;  5K9W A;  4WU3 A;  1ZZW A;  2BIJ A;  2I6J A;  4ZRT A;  5KA7 A;  1C83 A;  1YGR A;  5KA8 A;  2QDM A;  2VEY A;  4QAP A;  1J4X A;  5KAC A;  3QCG A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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