4Y5OA

Ccm2 hhd in complex with mekk3 npb1
Total Genus 27
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
27
sequence length
78
structure length
78
Chain Sequence
ASATELLQDYMLTLRTKLSSQEIQQFAALLHEYRNGASIHEFCINLRQLYGDSRKFLLLGLRPFIPEKDSQHFENFLE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex.
pubmed doi rcsb
molecule tags Transferase
source organism Homo sapiens
molecule keywords Malcavernin
total genus 27
structure length 78
sequence length 78
ec nomenclature
pdb deposition date 2015-02-11
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.1160.20 Mainly Alpha Up-down Bundle Paired amphipathic helix 2 (pah2 repeat) Paired amphipathic helix 2 (pah2 repeat) 4y5oA00
3K1RA 4YKDA 2LSRA 2KBRA 5F3XA 4YKCA 4Y5OA 4FQNA 2KBQA 4YL6A
chains in the Genus database with same CATH superfamily
1G1EB 2F05A 2KBRA 1S5RB 1E91A 4FQNA 1S5QB 4YL6A 3K1RA 1PD7A 2RMSA 5F3XA 4YKCA 4Y5OA 2CZYA 2LD7B 2KBQA 2L9SB 4YKDA 2LSRA 2CR7A 2RMRA
chains in the Genus database with same CATH topology
3K1RA 4YKDA 2LSRA 2KBRA 5F3XA 4YKCA 4Y5OA 4FQNA 2KBQA 4YL6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3K1R A;  4YKD A;  2LSR A;  2KBR A;  5F3X A;  4YKC A;  4Y5O A;  4FQN A;  2KBQ A;  4YL6 A; 
#chains in the Genus database with same CATH topology
 1G1E B;  2F05 A;  2KBR A;  1S5R B;  1E91 A;  4FQN A;  1S5Q B;  4YL6 A;  3K1R A;  1PD7 A;  2RMS A;  5F3X A;  4YKC A;  4Y5O A;  2CZY A;  2LD7 B;  2KBQ A;  2L9S B;  4YKD A;  2LSR A;  2CR7 A;  2RMR A; 
#chains in the Genus database with same CATH homology
 3K1R A;  4YKD A;  2LSR A;  2KBR A;  5F3X A;  4YKC A;  4Y5O A;  4FQN A;  2KBQ A;  4YL6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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