4YFNA

Escherichia coli rna polymerase in complex with squaramide compound 14 (n-[3,4-dioxo-2-(4-{[4-(trifluoromethyl)benzyl]amino}piperidin-1-yl)cyclobut-1-en-1-yl]-3,5-dimethyl-1,2-oxazole-4-sulfonamide)
Total Genus 38
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
38
sequence length
235
structure length
235
Chain Sequence
b'MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLNKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIHSEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIRRAATILAEQLEAFVDLR'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords DNA-directed RNA polymerase subunit alpha
molecule tags Transcription/transcription inhibitor
source organism Escherichia coli o139:h28 (strain e24377a / etec)
publication title X-ray Crystal Structures of Escherichia coli RNA Polymerase with Switch Region Binding Inhibitors Enable Rational Design of Squaramides with an Improved Fraction Unbound to Human Plasma Protein.
pubmed doi rcsb
total genus 38
structure length 235
sequence length 235
chains with identical sequence B, G, H
ec nomenclature ec 2.7.7.6: DNA-directed RNA polymerase.
pdb deposition date 2015-02-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01000 RNA_pol_A_bac RNA polymerase Rpb3/RpoA insert domain
A PF01193 RNA_pol_L RNA polymerase Rpb3/Rpb11 dimerisation domain
A PF03118 RNA_pol_A_CTD Bacterial RNA polymerase, alpha chain C terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.170.120.12 Mainly Beta Beta Complex RNA Polymerase Alpha Subunit; Chain A, domain 2 DNA-directed RNA polymerase, insert domain 4yfnA02
3.30.1360.10 Alpha Beta 2-Layer Sandwich Gyrase A; domain 2 RNA polymerase, RBP11-like subunit 4yfnA01
4A3GC 3HOZK 4A3MC 4MQ9A 5FLMK 3PO3C 4NOIA 3S1NC 4XLNA 5IP7K 5IP7C 2YU9C 4MEXA 2YU9K 3I4NK 1I6VA 2JA7C 4Q5SA 4A3GK 5M3FK 3GTQC 5IYCK 4A3EK 3H3VL 3GTGC 3DXJA 4LLGA 2WAQL 4LK0A 4OIPA 1SMYA 2PMZD 3S2DC 4AYBD 2WB1L 1Y1WC 1BDFA 4Y7NK 3GTLC 4A3JK 3M3YC 2NVYK 1XPPA 4GZYA 3CQZK 2PA8D 3FKIC 1TWHK 2JA5K 4AYBL 3HOWK 3RZOK 3S1MK 4A3CK 2E2JC 5C44K 4A3BC 3PO2K 4C3HC 3HOXC 4X6AC 5D4DA 2VUMC 4A3KC 1ZYRA 3S2HK 3PO3K 3HOWC 5FLMC 4A3IK 3CQZC 3HKZD 3HOZC 1I50C 2R93C 1I6HC 2R92K 3M3YK 4A3JC 3S1QK 2NVXC 3RZDC 4Q4ZA 4C3JK 5TMCA 4BY1C 2E2IK 3GTPK 1SFOK 3S16K 1TWGK 5C3EK 4QIWL 3GTGK 3K7AC 4ZH4A 5C4JK 3GTQK 5M3MK 3S15K 4KN4A 2JA8C 1K83C 3H0GC 4OIRA 3H3VD 4Y7NC 5C4XC 1TWCK 2B63K 2JA7K 3S1RK 4JK1A 5TMFA 3I4NC 4A3FC 4G7ZA 1TWAK 4BBSK 4C2MK 3S1NK 4C3IC 4OINA 5IYDC 4QJVA 4BXXK 4YFKA 5IYBK 2NVTK 1TWAC 4BBSC 1R9TC 2O5IA 3M4OK 3S1RC 4A3MK 5C4XK 4BBRC 3S15C 1WCMC 3HOUC 3HOVC 1TWFK 2JA6K 4OIQA 4A3DK 4A93K 2E2HC 4XSZA 3GTJK 3GTJC 5C3EC 2E2HK 3GTMK 1TWFC 2JA6C 1YNNA 2E2IC 4OIOA 4A3DC 5M5XK 3HKZL 4BY1K 3HOUK 1I3QC 5IP9C 2NVQC 4A3LK 3S14C 2NVXK 4BY7K 4A3EC 4YG2A 1R9TK 3I4MK 5IYBC 4LK1A 2R92C 5FJ8K 3S17K 3WODA 2Y0SL 3S17C 4C2MC 4A3KK 2A6EA 4C3HK 4A3FK 2A69A 3GTKK 4A3BK 4LJZA 4XLPA 1TWCC 2B63C 2PPBA 1Y1VK 3RZOC 3S1MC 4G7OA 4A3CC 4A3LC 1I3QK 2PA8L 5IP9K 2NVQK 4YFXA 3EQLA 5C4JC 3GTMC 3K7AK 2R7ZK 2WAQD 4XSXA 3GTOK 1TWGC 2WB1D 3GTOC 2R7ZC 4A93C 3S2DK 3HOVK 1WCMK 3RZDK 4G7HA 1Y1VC 3S1QC 3GTKC 1I6HK 1I50K 2R93K 4QJVB 2NVTC 4A3IC 5M5YK 5IYDK 2VUMK 2BE5A 3S2HC 4BXXC 4C3IK 3HOXK 4X6AK 1IW7A 3PO2C 1YNJA 3I4MC 2Y0SD 1HQMA 4KN7A 5C44C 2E2JK 4BY7C 3S14K 1TWHC 2JA5C 2PMZL 3FKIK 2A6HA 1K83K 2NVYC 4YFNA 3H0GK 2CW0A 2O5JA 5M5WK 2JA8K 2A68A 3GTLK 4Y52K 1Y1WK 3HOYK 1SFOC 3GTPC 3HOYC 3S16C 4C3JC 5IYCC 4KMUA 4BBRK 4MEYA 3M4OC 4Y52C 4QIWD
chains in the Genus database with same CATH superfamily
4MQ9A 5FLMK 4P5BA 2YU9C 1I50A 4GTLA 4A3GK 1ZVUA 4G0WA 1XXAA 3AD9C 3GTGC 3DXJA 4LLGA 2WAQL 3S2DC 4AYBD 3MMLB 4WF9S 4LQYA 1Y1WC 2ZJPS 1BDFA 1JVIA 1XXBA 2NVYK 4GZYA 1TWHK 4A3CK 1VLOA 4GFQA 5C44K 4GTEA 3GTQA 3CAGA 3HOXC 3S2HK 5D4DA 1XZPA 1B4BA 3HOZC 1I6HC 2NVXC 3RZDC 3DLLS 4BKWA 5HQHA 4Q4ZA 4C3JK 2E2IK 4FM9A 1TWHA 3TTGA 3K7AC 5C4JK 2P8TA 3GTQK 2XCOA 4KN4A 5TJ3A 4OIRA 2JA7K 1TWCK 2B63K 4GTBA 1VGXA 3S1NK 4C3IC 1DD5A 4YFKA 1C0AA 2RH6A 1R9TC 2O5IA 1RU0A 3M4OK 5C4XK 1USMA 5DM7S 4KATA 4KMHA 3ERED 4A93K 1TWCA 2B63A 3BUEA 1TWFC 4A3DC 4BY1K 3HOUK 2KQ1A 3HKZL 5IP9C 2NVQC 1DCPA 4YG2A 2R92C 1WCMA 5FJ8K 4WCES 4A3KK 2CFAA 4C3HK 2PPBA 3RZOC 4G7OA 1F7VA 3A8IA 4KC6A 4BLAA 1EI6A 5EGEA 3TFIA 2GSNA 1TWGC 1WSRA 3HOVK 1WCMK 4G7HA 1IBAA 3S1QC 3ADAC 1I50K 2GAGC 1V5VA 5IYDK 4X6AK 1R9TA 1IW7A 3TFJA 4LR2A 4Y7NK 2A6HA 1K83K 2JA8K 2CW0A 1J6WA 3GTLK 3A8KA 3TFHA 3HOYK 1SFOC 3HXAA 1VRQC 1ZBSA 4KMUA 4MEYA 4RMFA 1O27A 3M4OC 4KDDA 2L5NA 4Y52C 4QIWD 2RGRA 4A3MC 3S1NC 5IP7K 5IP7C 1WSVA 1IQ0A 4XCHA 3GTLA 1ISEA 4BLBA 2JA7C 1YX2A 5M3FK 4P5AA 4G0UA 3GTQC 3AQOA 5CJ9A 4OIPA 1SMYA 2W7VA 2JA7A 2V6TA 5EGHA 3SZYA 1WQGA 3GTLC 3GTGA 3T00A 3NUHA 4AYBL 4X6AC 5JVHS 1ZYRA 3GEHA 3PO3K 3HKZD 1I50C 1XZQA 4WILA 4KARA 3S1QK 1O24A 4M1XA 3GTPK 5IOTA 1F9NA 1USOA 1TWGK 1WOOA 3GTGK 5HL7S 2KXYA 1PJ6A 3H0GC 4AH6A 3V4GA 4G7ZA 2KWAA 4BBSK 4KASA 4QJVA 4GTFA 1TWAC 3A8JA 3S1RC 1TWGA 1J98A 3S15C 3HOUC 1TWFK 3N3YA 4A3DK 1WIHA 3OPFA 5C3EC 1O28A 3GTMK 1YNNA 3S14C 4BY7K 1R9TK 3I4MK 1WOPA 3WODA 1K83A 1TWFA 3N0BA 4A3BK 4XLPA 1TWCC 2B63C 3S1MC 3GEEA 4DDQA 1WQFA 3EQLA 5C4JC 3GTMC 3K7AK 2WAQD 4KB2A 1BJTA 1KQ4A 4C45A 4U67S 5IOSA 3RZDK 1UV7A 1F7UA 2CFAB 1I6HK 2ZJRS 2Y3PA 1WQHA 3S2HC 3HOXK 5C44C 1HQMA 3CF5S 1TWHC 3H0GK 2NVYC 4YFNA 4KB4A 2O5JA 2V6SA 1XZQB 1Y1WK 4O2DA 3OEPA 3LYWA 1ZXOA 3GTPC 4ILDA 4BBRK 3FOFA 4A3GC 4KM9A 3PO3C 4XLNA 2YU9K 2R93A 4WFBS 1I6VA 1Y1WA 3GTPA 3H3VL 5CHPA 1BS2A 3L4JA 4J3NA 2WB1L 3PIPS 4KMAA 3M3YC 1SFOA 2YU9A 2PA8D 3FKIC 4GTCA 3HOWK 3S1MK 1FEUA 4A3BC 3BP8C 1G51A 5E68A 5HL8A 2VUMC 4A3IK 3CQZC 1J6VA 4A3JC 1JQWA 5IORA 5TMCA 1EH1A 3Q3QA 4KMDA 3GTMA 1SFOK 3VA7A 5C3EK 5JVGS 1IL2A 3S15K 2JA8C 1K83C 4Y7NC 3S1RK 4JK1A 5TMFA 3I4NC 2P5MA 1TWAK 3GEIA 5IYDC 4IO9S 4BBSC 1INNA 2GSUA 3N0CA 1DCHA 4G0VA 2GAHC 4GTAA 1WCMC 2JA6K 3HOVC 4FZBA 2R92A 4OIQA 3AH5A 3GTJK 3T01A 4KM8A 2E2HK 1DCOA 5M5XK 1TWAA 3GTOA 2FQTA 5IYBC 4LK1A 4WFAS 1IE0A 2Y0SL 3H0GA 4C2MC 2A6EA 2JA6A 4A3FK 2A69A 1WORA 3GTKK 1Y1VK 1ZQ1C 3LPXA 3GTJA 2NVQK 5IP9K 2E2HA 4YFXA 1EK8A 4WJ3M 2R7ZK 3GTOK 4XSXA 1J6XA 1O25A 2WB1D 3GTOC 2R7ZC 5JFEA 4A93C 3AD8C 3FHZA 1Y1VC 3GTKC 1AB4A 3SZZA 2R93K 2ZJQS 5M5YK 1WOSA 2NVXA 4C3IK 1EFWA 3PO2C 2Y0SD 4KN7A 2E2JK 2EBBA 2JA5C 3BP3A 3LAJA 4A3MK 4Y52K 2A68A 4WJ4A 1B4AA 1JOEA 4P9SA 3HOYC 1EQRA 4C3JC 5IYCC 3OREA 5IOQA 3G4AA 1VH2A 3HOZK 4NOIA 4MEXA 3CQZA 2KPUA 3I4NK 4Q5SA 2ZUEA 2XCQA 5IYCK 3FKIA 3T02A 4LK0A 2PMZD 1O2AA 4A3JK 4IOAS 1XPPA 3CQZK 2JA5K 3RZOK 2E2JC 2FQOA 3PO2K 4C3HC 4A3KC 3HOWC 1VJEA 5FLMC 2R92K 2R93C 1PJ7A 3M3YK 1XXCA 2PHCB 4KAWX 4BY1C 1F93A 3S16K 4IOCS 4QIWL 2JA5A 2ZFZA 4ZH4A 1O29A 1L0WA 3S0XA 5M3MK 3H3VD 5C4XC 5JVOA 4A3FC 4PAAA 1IS1A 2NVYA 4C2MK 3GTKA 4BXXK 4OINA 1Y1VA 1GE9A 5DM6S 1PJ5A 5IYBK 2NVTK 3G4CA 2R7ZA 4BBRC 3AQPA 1X31C 2E2HC 4XSZA 3GTJC 1I3QA 2V6UA 2E2IA 2JA6C 2E2IC 3FOEA 4OIOA 4LOWA 5L46A 1I3QC 4A3LK 2NVXK 3QX3A 4A3EC 2D6FC 1O2BA 4PABA 3S17K 1YCLA 2GSOA 4GTDA 3GDZA 3S17C 3LAPA 4LJZA 4A3EK 4A3CC 4A3LC 1I3QK 2PA8L 1O26A 1BGWA 2JH3A 3S2DK 3JSTA 4QJVB 2NVTC 4A3IC 1HI9A 3AD7C 3GSIA 2BE5A 4BXXC 2VUMK 3PIOS 1XZPB 1YNJA 3I4MC 3IPJA 4BY7C 3S14K 3FKIK 2PMZL 5M5WK 2L3UA 3L4KA 1O2FB 2ZUFA 2XCRB 4GT9A 3S16C 4WFNS 2VUMA 3GIRA
chains in the Genus database with same CATH topology
4A3GC 3HOZK 4A3MC 4MQ9A 5FLMK 3PO3C 4NOIA 3S1NC 4XLNA 5IP7K 5IP7C 2YU9C 4MEXA 2YU9K 3I4NK 1I6VA 2JA7C 4Q5SA 4A3GK 5M3FK 3GTQC 5IYCK 4A3EK 3H3VL 3GTGC 3DXJA 4LLGA 2WAQL 4LK0A 4OIPA 1SMYA 2PMZD 3S2DC 4AYBD 2WB1L 1Y1WC 1BDFA 4Y7NK 3GTLC 4A3JK 3M3YC 2NVYK 1XPPA 4GZYA 3CQZK 2PA8D 3FKIC 1TWHK 2JA5K 4AYBL 3HOWK 3RZOK 3S1MK 4A3CK 2E2JC 5C44K 4A3BC 3PO2K 4C3HC 3HOXC 4X6AC 5D4DA 2VUMC 4A3KC 1ZYRA 3S2HK 3PO3K 3HOWC 5FLMC 4A3IK 3CQZC 3HKZD 3HOZC 1I50C 2R93C 1I6HC 2R92K 3M3YK 4A3JC 3S1QK 2NVXC 3RZDC 4Q4ZA 4C3JK 5TMCA 4BY1C 2E2IK 3GTPK 1SFOK 3S16K 1TWGK 5C3EK 4QIWL 3GTGK 3K7AC 4ZH4A 5C4JK 3GTQK 5M3MK 3S15K 4KN4A 2JA8C 1K83C 3H0GC 4OIRA 3H3VD 4Y7NC 5C4XC 1TWCK 2B63K 2JA7K 3S1RK 4JK1A 5TMFA 3I4NC 4A3FC 4G7ZA 1TWAK 4BBSK 4C2MK 3S1NK 4C3IC 4OINA 5IYDC 4QJVA 4BXXK 4YFKA 5IYBK 2NVTK 1TWAC 4BBSC 1R9TC 2O5IA 3M4OK 3S1RC 4A3MK 5C4XK 4BBRC 3S15C 1WCMC 3HOUC 3HOVC 1TWFK 2JA6K 4OIQA 4A3DK 4A93K 2E2HC 4XSZA 3GTJK 3GTJC 5C3EC 2E2HK 3GTMK 1TWFC 2JA6C 1YNNA 2E2IC 4OIOA 4A3DC 5M5XK 3HKZL 4BY1K 3HOUK 1I3QC 5IP9C 2NVQC 4A3LK 3S14C 2NVXK 4BY7K 4A3EC 4YG2A 1R9TK 3I4MK 5IYBC 4LK1A 2R92C 5FJ8K 3S17K 3WODA 2Y0SL 3S17C 4C2MC 4A3KK 2A6EA 4C3HK 4A3FK 2A69A 3GTKK 4A3BK 4LJZA 4XLPA 1TWCC 2B63C 2PPBA 1Y1VK 3RZOC 3S1MC 4G7OA 4A3CC 4A3LC 1I3QK 2PA8L 5IP9K 2NVQK 4YFXA 3EQLA 5C4JC 3GTMC 3K7AK 2R7ZK 2WAQD 4XSXA 3GTOK 1TWGC 2WB1D 3GTOC 2R7ZC 4A93C 3S2DK 3HOVK 1WCMK 3RZDK 4G7HA 1Y1VC 3S1QC 3GTKC 1I6HK 1I50K 2R93K 4QJVB 2NVTC 4A3IC 5M5YK 5IYDK 2VUMK 2BE5A 3S2HC 4BXXC 4C3IK 3HOXK 4X6AK 1IW7A 3PO2C 1YNJA 3I4MC 2Y0SD 1HQMA 4KN7A 5C44C 2E2JK 4BY7C 3S14K 1TWHC 2JA5C 2PMZL 3FKIK 2A6HA 1K83K 2NVYC 4YFNA 3H0GK 2CW0A 2O5JA 5M5WK 2JA8K 2A68A 3GTLK 4Y52K 1Y1WK 3HOYK 1SFOC 3GTPC 3HOYC 3S16C 4C3JC 5IYCC 4KMUA 4BBRK 4MEYA 3M4OC 4Y52C 4QIWD
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4A3G C;  3HOZ K;  4A3M C;  4MQ9 A;  5FLM K;  3PO3 C;  4NOI A;  3S1N C;  4XLN A;  5IP7 K;  5IP7 C;  2YU9 C;  4MEX A;  2YU9 K;  3I4N K;  1I6V A;  2JA7 C;  4Q5S A;  4A3G K;  5M3F K;  3GTQ C;  5IYC K;  4A3E K;  3H3V L;  3GTG C;  3DXJ A;  4LLG A;  2WAQ L;  4LK0 A;  4OIP A;  1SMY A;  2PMZ D;  3S2D C;  4AYB D;  2WB1 L;  1Y1W C;  1BDF A;  4Y7N K;  3GTL C;  4A3J K;  3M3Y C;  2NVY K;  1XPP A;  4GZY A;  3CQZ K;  2PA8 D;  3FKI C;  1TWH K;  2JA5 K;  4AYB L;  3HOW K;  3RZO K;  3S1M K;  4A3C K;  2E2J C;  5C44 K;  4A3B C;  3PO2 K;  4C3H C;  3HOX C;  4X6A C;  5D4D A;  2VUM C;  4A3K C;  1ZYR A;  3S2H K;  3PO3 K;  3HOW C;  5FLM C;  4A3I K;  3CQZ C;  3HKZ D;  3HOZ C;  1I50 C;  2R93 C;  1I6H C;  2R92 K;  3M3Y K;  4A3J C;  3S1Q K;  2NVX C;  3RZD C;  4Q4Z A;  4C3J K;  5TMC A;  4BY1 C;  2E2I K;  3GTP K;  1SFO K;  3S16 K;  1TWG K;  5C3E K;  4QIW L;  3GTG K;  3K7A C;  4ZH4 A;  5C4J K;  3GTQ K;  5M3M K;  3S15 K;  4KN4 A;  2JA8 C;  1K83 C;  3H0G C;  4OIR A;  3H3V D;  4Y7N C;  5C4X C;  1TWC K;  2B63 K;  2JA7 K;  3S1R K;  4JK1 A;  5TMF A;  3I4N C;  4A3F C;  4G7Z A;  1TWA K;  4BBS K;  4C2M K;  3S1N K;  4C3I C;  4OIN A;  5IYD C;  4QJV A;  4BXX K;  4YFK A;  5IYB K;  2NVT K;  1TWA C;  4BBS C;  1R9T C;  2O5I A;  3M4O K;  3S1R C;  4A3M K;  5C4X K;  4BBR C;  3S15 C;  1WCM C;  3HOU C;  3HOV C;  1TWF K;  2JA6 K;  4OIQ A;  4A3D K;  4A93 K;  2E2H C;  4XSZ A;  3GTJ K;  3GTJ C;  5C3E C;  2E2H K;  3GTM K;  1TWF C;  2JA6 C;  1YNN A;  2E2I C;  4OIO A;  4A3D C;  5M5X K;  3HKZ L;  4BY1 K;  3HOU K;  1I3Q C;  5IP9 C;  2NVQ C;  4A3L K;  3S14 C;  2NVX K;  4BY7 K;  4A3E C;  4YG2 A;  1R9T K;  3I4M K;  5IYB C;  4LK1 A;  2R92 C;  5FJ8 K;  3S17 K;  3WOD A;  2Y0S L;  3S17 C;  4C2M C;  4A3K K;  2A6E A;  4C3H K;  4A3F K;  2A69 A;  3GTK K;  4A3B K;  4LJZ A;  4XLP A;  1TWC C;  2B63 C;  2PPB A;  1Y1V K;  3RZO C;  3S1M C;  4G7O A;  4A3C C;  4A3L C;  1I3Q K;  2PA8 L;  5IP9 K;  2NVQ K;  4YFX A;  3EQL A;  5C4J C;  3GTM C;  3K7A K;  2R7Z K;  2WAQ D;  4XSX A;  3GTO K;  1TWG C;  2WB1 D;  3GTO C;  2R7Z C;  4A93 C;  3S2D K;  3HOV K;  1WCM K;  3RZD K;  4G7H A;  1Y1V C;  3S1Q C;  3GTK C;  1I6H K;  1I50 K;  2R93 K;  4QJV B;  2NVT C;  4A3I C;  5M5Y K;  5IYD K;  2VUM K;  2BE5 A;  3S2H C;  4BXX C;  4C3I K;  3HOX K;  4X6A K;  1IW7 A;  3PO2 C;  1YNJ A;  3I4M C;  2Y0S D;  1HQM A;  4KN7 A;  5C44 C;  2E2J K;  4BY7 C;  3S14 K;  1TWH C;  2JA5 C;  2PMZ L;  3FKI K;  2A6H A;  1K83 K;  2NVY C;  4YFN A;  3H0G K;  2CW0 A;  2O5J A;  5M5W K;  2JA8 K;  2A68 A;  3GTL K;  4Y52 K;  1Y1W K;  3HOY K;  1SFO C;  3GTP C;  3HOY C;  3S16 C;  4C3J C;  5IYC C;  4KMU A;  4BBR K;  4MEY A;  3M4O C;  4Y52 C;  4QIW D; 
#chains in the Genus database with same CATH topology
 4MQ9 A;  5FLM K;  4P5B A;  2YU9 C;  1I50 A;  4GTL A;  4A3G K;  1ZVU A;  4G0W A;  1XXA A;  3AD9 C;  3GTG C;  3DXJ A;  4LLG A;  2WAQ L;  3S2D C;  4AYB D;  3MML B;  4WF9 S;  4LQY A;  1Y1W C;  2ZJP S;  1BDF A;  1JVI A;  1XXB A;  2NVY K;  4GZY A;  1TWH K;  4A3C K;  1VLO A;  4GFQ A;  5C44 K;  4GTE A;  3GTQ A;  3CAG A;  3HOX C;  3S2H K;  5D4D A;  1XZP A;  1B4B A;  3HOZ C;  1I6H C;  2NVX C;  3RZD C;  3DLL S;  4BKW A;  5HQH A;  4Q4Z A;  4C3J K;  2E2I K;  4FM9 A;  1TWH A;  3TTG A;  3K7A C;  5C4J K;  2P8T A;  3GTQ K;  2XCO A;  4KN4 A;  5TJ3 A;  4OIR A;  2JA7 K;  1TWC K;  2B63 K;  4GTB A;  1VGX A;  3S1N K;  4C3I C;  1DD5 A;  4YFK A;  1C0A A;  2RH6 A;  1R9T C;  2O5I A;  1RU0 A;  3M4O K;  5C4X K;  1USM A;  5DM7 S;  4KAT A;  4KMH A;  3ERE D;  4A93 K;  1TWC A;  2B63 A;  3BUE A;  1TWF C;  4A3D C;  4BY1 K;  3HOU K;  2KQ1 A;  3HKZ L;  5IP9 C;  2NVQ C;  1DCP A;  4YG2 A;  2R92 C;  1WCM A;  5FJ8 K;  4WCE S;  4A3K K;  2CFA A;  4C3H K;  2PPB A;  3RZO C;  4G7O A;  1F7V A;  3A8I A;  4KC6 A;  4BLA A;  1EI6 A;  5EGE A;  3TFI A;  2GSN A;  1TWG C;  1WSR A;  3HOV K;  1WCM K;  4G7H A;  1IBA A;  3S1Q C;  3ADA C;  1I50 K;  2GAG C;  1V5V A;  5IYD K;  4X6A K;  1R9T A;  1IW7 A;  3TFJ A;  4LR2 A;  4Y7N K;  2A6H A;  1K83 K;  2JA8 K;  2CW0 A;  1J6W A;  3GTL K;  3A8K A;  3TFH A;  3HOY K;  1SFO C;  3HXA A;  1VRQ C;  1ZBS A;  4KMU A;  4MEY A;  4RMF A;  1O27 A;  3M4O C;  4KDD A;  2L5N A;  4Y52 C;  4QIW D;  2RGR A;  4A3M C;  3S1N C;  5IP7 K;  5IP7 C;  1WSV A;  1IQ0 A;  4XCH A;  3GTL A;  1ISE A;  4BLB A;  2JA7 C;  1YX2 A;  5M3F K;  4P5A A;  4G0U A;  3GTQ C;  3AQO A;  5CJ9 A;  4OIP A;  1SMY A;  2W7V A;  2JA7 A;  2V6T A;  5EGH A;  3SZY A;  1WQG A;  3GTL C;  3GTG A;  3T00 A;  3NUH A;  4AYB L;  4X6A C;  5JVH S;  1ZYR A;  3GEH A;  3PO3 K;  3HKZ D;  1I50 C;  1XZQ A;  4WIL A;  4KAR A;  3S1Q K;  1O24 A;  4M1X A;  3GTP K;  5IOT A;  1F9N A;  1USO A;  1TWG K;  1WOO A;  3GTG K;  5HL7 S;  2KXY A;  1PJ6 A;  3H0G C;  4AH6 A;  3V4G A;  4G7Z A;  2KWA A;  4BBS K;  4KAS A;  4QJV A;  4GTF A;  1TWA C;  3A8J A;  3S1R C;  1TWG A;  1J98 A;  3S15 C;  3HOU C;  1TWF K;  3N3Y A;  4A3D K;  1WIH A;  3OPF A;  5C3E C;  1O28 A;  3GTM K;  1YNN A;  3S14 C;  4BY7 K;  1R9T K;  3I4M K;  1WOP A;  3WOD A;  1K83 A;  1TWF A;  3N0B A;  4A3B K;  4XLP A;  1TWC C;  2B63 C;  3S1M C;  3GEE A;  4DDQ A;  1WQF A;  3EQL A;  5C4J C;  3GTM C;  3K7A K;  2WAQ D;  4KB2 A;  1BJT A;  1KQ4 A;  4C45 A;  4U67 S;  5IOS A;  3RZD K;  1UV7 A;  1F7U A;  2CFA B;  1I6H K;  2ZJR S;  2Y3P A;  1WQH A;  3S2H C;  3HOX K;  5C44 C;  1HQM A;  3CF5 S;  1TWH C;  3H0G K;  2NVY C;  4YFN A;  4KB4 A;  2O5J A;  2V6S A;  1XZQ B;  1Y1W K;  4O2D A;  3OEP A;  3LYW A;  1ZXO A;  3GTP C;  4ILD A;  4BBR K;  3FOF A;  4A3G C;  4KM9 A;  3PO3 C;  4XLN A;  2YU9 K;  2R93 A;  4WFB S;  1I6V A;  1Y1W A;  3GTP A;  3H3V L;  5CHP A;  1BS2 A;  3L4J A;  4J3N A;  2WB1 L;  3PIP S;  4KMA A;  3M3Y C;  1SFO A;  2YU9 A;  2PA8 D;  3FKI C;  4GTC A;  3HOW K;  3S1M K;  1FEU A;  4A3B C;  3BP8 C;  1G51 A;  5E68 A;  5HL8 A;  2VUM C;  4A3I K;  3CQZ C;  1J6V A;  4A3J C;  1JQW A;  5IOR A;  5TMC A;  1EH1 A;  3Q3Q A;  4KMD A;  3GTM A;  1SFO K;  3VA7 A;  5C3E K;  5JVG S;  1IL2 A;  3S15 K;  2JA8 C;  1K83 C;  4Y7N C;  3S1R K;  4JK1 A;  5TMF A;  3I4N C;  2P5M A;  1TWA K;  3GEI A;  5IYD C;  4IO9 S;  4BBS C;  1INN A;  2GSU A;  3N0C A;  1DCH A;  4G0V A;  2GAH C;  4GTA A;  1WCM C;  2JA6 K;  3HOV C;  4FZB A;  2R92 A;  4OIQ A;  3AH5 A;  3GTJ K;  3T01 A;  4KM8 A;  2E2H K;  1DCO A;  5M5X K;  1TWA A;  3GTO A;  2FQT A;  5IYB C;  4LK1 A;  4WFA S;  1IE0 A;  2Y0S L;  3H0G A;  4C2M C;  2A6E A;  2JA6 A;  4A3F K;  2A69 A;  1WOR A;  3GTK K;  1Y1V K;  1ZQ1 C;  3LPX A;  3GTJ A;  2NVQ K;  5IP9 K;  2E2H A;  4YFX A;  1EK8 A;  4WJ3 M;  2R7Z K;  3GTO K;  4XSX A;  1J6X A;  1O25 A;  2WB1 D;  3GTO C;  2R7Z C;  5JFE A;  4A93 C;  3AD8 C;  3FHZ A;  1Y1V C;  3GTK C;  1AB4 A;  3SZZ A;  2R93 K;  2ZJQ S;  5M5Y K;  1WOS A;  2NVX A;  4C3I K;  1EFW A;  3PO2 C;  2Y0S D;  4KN7 A;  2E2J K;  2EBB A;  2JA5 C;  3BP3 A;  3LAJ A;  4A3M K;  4Y52 K;  2A68 A;  4WJ4 A;  1B4A A;  1JOE A;  4P9S A;  3HOY C;  1EQR A;  4C3J C;  5IYC C;  3ORE A;  5IOQ A;  3G4A A;  1VH2 A;  3HOZ K;  4NOI A;  4MEX A;  3CQZ A;  2KPU A;  3I4N K;  4Q5S A;  2ZUE A;  2XCQ A;  5IYC K;  3FKI A;  3T02 A;  4LK0 A;  2PMZ D;  1O2A A;  4A3J K;  4IOA S;  1XPP A;  3CQZ K;  2JA5 K;  3RZO K;  2E2J C;  2FQO A;  3PO2 K;  4C3H C;  4A3K C;  3HOW C;  1VJE A;  5FLM C;  2R92 K;  2R93 C;  1PJ7 A;  3M3Y K;  1XXC A;  2PHC B;  4KAW X;  4BY1 C;  1F93 A;  3S16 K;  4IOC S;  4QIW L;  2JA5 A;  2ZFZ A;  4ZH4 A;  1O29 A;  1L0W A;  3S0X A;  5M3M K;  3H3V D;  5C4X C;  5JVO A;  4A3F C;  4PAA A;  1IS1 A;  2NVY A;  4C2M K;  3GTK A;  4BXX K;  4OIN A;  1Y1V A;  1GE9 A;  5DM6 S;  1PJ5 A;  5IYB K;  2NVT K;  3G4C A;  2R7Z A;  4BBR C;  3AQP A;  1X31 C;  2E2H C;  4XSZ A;  3GTJ C;  1I3Q A;  2V6U A;  2E2I A;  2JA6 C;  2E2I C;  3FOE A;  4OIO A;  4LOW A;  5L46 A;  1I3Q C;  4A3L K;  2NVX K;  3QX3 A;  4A3E C;  2D6F C;  1O2B A;  4PAB A;  3S17 K;  1YCL A;  2GSO A;  4GTD A;  3GDZ A;  3S17 C;  3LAP A;  4LJZ A;  4A3E K;  4A3C C;  4A3L C;  1I3Q K;  2PA8 L;  1O26 A;  1BGW A;  2JH3 A;  3S2D K;  3JST A;  4QJV B;  2NVT C;  4A3I C;  1HI9 A;  3AD7 C;  3GSI A;  2BE5 A;  4BXX C;  2VUM K;  3PIO S;  1XZP B;  1YNJ A;  3I4M C;  3IPJ A;  4BY7 C;  3S14 K;  3FKI K;  2PMZ L;  5M5W K;  2L3U A;  3L4K A;  1O2F B;  2ZUF A;  2XCR B;  4GT9 A;  3S16 C;  4WFN S;  2VUM A;  3GIR A; 
#chains in the Genus database with same CATH homology
 4A3G C;  3HOZ K;  4A3M C;  4MQ9 A;  5FLM K;  3PO3 C;  4NOI A;  3S1N C;  4XLN A;  5IP7 K;  5IP7 C;  2YU9 C;  4MEX A;  2YU9 K;  3I4N K;  1I6V A;  2JA7 C;  4Q5S A;  4A3G K;  5M3F K;  3GTQ C;  5IYC K;  4A3E K;  3H3V L;  3GTG C;  3DXJ A;  4LLG A;  2WAQ L;  4LK0 A;  4OIP A;  1SMY A;  2PMZ D;  3S2D C;  4AYB D;  2WB1 L;  1Y1W C;  1BDF A;  4Y7N K;  3GTL C;  4A3J K;  3M3Y C;  2NVY K;  1XPP A;  4GZY A;  3CQZ K;  2PA8 D;  3FKI C;  1TWH K;  2JA5 K;  4AYB L;  3HOW K;  3RZO K;  3S1M K;  4A3C K;  2E2J C;  5C44 K;  4A3B C;  3PO2 K;  4C3H C;  3HOX C;  4X6A C;  5D4D A;  2VUM C;  4A3K C;  1ZYR A;  3S2H K;  3PO3 K;  3HOW C;  5FLM C;  4A3I K;  3CQZ C;  3HKZ D;  3HOZ C;  1I50 C;  2R93 C;  1I6H C;  2R92 K;  3M3Y K;  4A3J C;  3S1Q K;  2NVX C;  3RZD C;  4Q4Z A;  4C3J K;  5TMC A;  4BY1 C;  2E2I K;  3GTP K;  1SFO K;  3S16 K;  1TWG K;  5C3E K;  4QIW L;  3GTG K;  3K7A C;  4ZH4 A;  5C4J K;  3GTQ K;  5M3M K;  3S15 K;  4KN4 A;  2JA8 C;  1K83 C;  3H0G C;  4OIR A;  3H3V D;  4Y7N C;  5C4X C;  1TWC K;  2B63 K;  2JA7 K;  3S1R K;  4JK1 A;  5TMF A;  3I4N C;  4A3F C;  4G7Z A;  1TWA K;  4BBS K;  4C2M K;  3S1N K;  4C3I C;  4OIN A;  5IYD C;  4QJV A;  4BXX K;  4YFK A;  5IYB K;  2NVT K;  1TWA C;  4BBS C;  1R9T C;  2O5I A;  3M4O K;  3S1R C;  4A3M K;  5C4X K;  4BBR C;  3S15 C;  1WCM C;  3HOU C;  3HOV C;  1TWF K;  2JA6 K;  4OIQ A;  4A3D K;  4A93 K;  2E2H C;  4XSZ A;  3GTJ K;  3GTJ C;  5C3E C;  2E2H K;  3GTM K;  1TWF C;  2JA6 C;  1YNN A;  2E2I C;  4OIO A;  4A3D C;  5M5X K;  3HKZ L;  4BY1 K;  3HOU K;  1I3Q C;  5IP9 C;  2NVQ C;  4A3L K;  3S14 C;  2NVX K;  4BY7 K;  4A3E C;  4YG2 A;  1R9T K;  3I4M K;  5IYB C;  4LK1 A;  2R92 C;  5FJ8 K;  3S17 K;  3WOD A;  2Y0S L;  3S17 C;  4C2M C;  4A3K K;  2A6E A;  4C3H K;  4A3F K;  2A69 A;  3GTK K;  4A3B K;  4LJZ A;  4XLP A;  1TWC C;  2B63 C;  2PPB A;  1Y1V K;  3RZO C;  3S1M C;  4G7O A;  4A3C C;  4A3L C;  1I3Q K;  2PA8 L;  5IP9 K;  2NVQ K;  4YFX A;  3EQL A;  5C4J C;  3GTM C;  3K7A K;  2R7Z K;  2WAQ D;  4XSX A;  3GTO K;  1TWG C;  2WB1 D;  3GTO C;  2R7Z C;  4A93 C;  3S2D K;  3HOV K;  1WCM K;  3RZD K;  4G7H A;  1Y1V C;  3S1Q C;  3GTK C;  1I6H K;  1I50 K;  2R93 K;  4QJV B;  2NVT C;  4A3I C;  5M5Y K;  5IYD K;  2VUM K;  2BE5 A;  3S2H C;  4BXX C;  4C3I K;  3HOX K;  4X6A K;  1IW7 A;  3PO2 C;  1YNJ A;  3I4M C;  2Y0S D;  1HQM A;  4KN7 A;  5C44 C;  2E2J K;  4BY7 C;  3S14 K;  1TWH C;  2JA5 C;  2PMZ L;  3FKI K;  2A6H A;  1K83 K;  2NVY C;  4YFN A;  3H0G K;  2CW0 A;  2O5J A;  5M5W K;  2JA8 K;  2A68 A;  3GTL K;  4Y52 K;  1Y1W K;  3HOY K;  1SFO C;  3GTP C;  3HOY C;  3S16 C;  4C3J C;  5IYC C;  4KMU A;  4BBR K;  4MEY A;  3M4O C;  4Y52 C;  4QIW D; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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