4YHDA

Staphylococcal alpha-hemolysin h35a mutant monomer
Total Genus 64
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
64
sequence length
290
structure length
281
Chain Sequence
INIKTGTTDIGSNTTVKTGDLVTYDKENGMAKKVFYSFIDDKNHNKKLLVIRTKGTIAGQYRVYSEEGANKSGLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYGNQLFMKTRNGSMKAAENFLDPNKASSLLSSGFSPDFATVITMDRKASKQQTNIDVIYERVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTNL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Alpha-hemolysin
publication title Structural basis for pore-forming mechanism of staphylococcal alpha-hemolysin
pubmed doi rcsb
source organism Staphylococcus aureus
total genus 64
structure length 281
sequence length 290
chains with identical sequence B, C, D, E, G
ec nomenclature
pdb deposition date 2015-02-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF07968 Leukocidin Leukocidin/Hemolysin toxin family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.240.10 Mainly Beta Distorted Sandwich Leukocidin-like Leukocidin/porin MspA 4yhdA00
4P1YA 5K59C 2QK7B 2YGTA 4IDJA 4U6VA 3LKFA 7AHLA 3M4EA 4TW1A 4P1XA 3M2LA 4IZLA 3ANZA 3B07A 4H56A 4YHDA 3M4DA 4IYTA 4P1YB 2LKFA 5K59A 3M3RA 4IYAA 3ROHA 2QK7A 4TW1B 4I0NA 4J0OA 4P1XB 1T5RA 4IYCA 3B07B 3O44A 4P24A 1PVLA 4Q7GA 1LKFA
chains in the Genus database with same CATH superfamily
4P1YA 5K59C 2QK7B 2YGTA 4IDJA 4U6VA 3LKFA 7AHLA 3M4EA 4TW1A 4P1XA 3M2LA 4IZLA 3ANZA 3B07A 4H56A 4YHDA 3M4DA 4IYTA 4P1YB 2LKFA 5K59A 3M3RA 4IYAA 3ROHA 2QK7A 4TW1B 4I0NA 4J0OA 4P1XB 1T5RA 4IYCA 3B07B 3O44A 4P24A 1PVLA 1XEZA 4Q7GA 1LKFA
chains in the Genus database with same CATH topology
4P1YA 5K59C 2QK7B 2YGTA 4IDJA 4U6VA 3LKFA 7AHLA 3M4EA 4TW1A 4P1XA 3M2LA 4IZLA 3ANZA 3B07A 4H56A 4YHDA 3M4DA 4IYTA 4P1YB 2LKFA 5K59A 3M3RA 4IYAA 3ROHA 2QK7A 4TW1B 4I0NA 4J0OA 4P1XB 1T5RA 4IYCA 3B07B 3O44A 4P24A 1PVLA 4Q7GA 1LKFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4P1Y A;  5K59 C;  2QK7 B;  2YGT A;  4IDJ A;  4U6V A;  3LKF A;  7AHL A;  3M4E A;  4TW1 A;  4P1X A;  3M2L A;  4IZL A;  3ANZ A;  3B07 A;  4H56 A;  4YHD A;  3M4D A;  4IYT A;  4P1Y B;  2LKF A;  5K59 A;  3M3R A;  4IYA A;  3ROH A;  2QK7 A;  4TW1 B;  4I0N A;  4J0O A;  4P1X B;  1T5R A;  4IYC A;  3B07 B;  3O44 A;  4P24 A;  1PVL A;  4Q7G A;  1LKF A; 
#chains in the Genus database with same CATH topology
 4P1Y A;  5K59 C;  2QK7 B;  2YGT A;  4IDJ A;  4U6V A;  3LKF A;  7AHL A;  3M4E A;  4TW1 A;  4P1X A;  3M2L A;  4IZL A;  3ANZ A;  3B07 A;  4H56 A;  4YHD A;  3M4D A;  4IYT A;  4P1Y B;  2LKF A;  5K59 A;  3M3R A;  4IYA A;  3ROH A;  2QK7 A;  4TW1 B;  4I0N A;  4J0O A;  4P1X B;  1T5R A;  4IYC A;  3B07 B;  3O44 A;  4P24 A;  1PVL A;  1XEZ A;  4Q7G A;  1LKF A; 
#chains in the Genus database with same CATH homology
 4P1Y A;  5K59 C;  2QK7 B;  2YGT A;  4IDJ A;  4U6V A;  3LKF A;  7AHL A;  3M4E A;  4TW1 A;  4P1X A;  3M2L A;  4IZL A;  3ANZ A;  3B07 A;  4H56 A;  4YHD A;  3M4D A;  4IYT A;  4P1Y B;  2LKF A;  5K59 A;  3M3R A;  4IYA A;  3ROH A;  2QK7 A;  4TW1 B;  4I0N A;  4J0O A;  4P1X B;  1T5R A;  4IYC A;  3B07 B;  3O44 A;  4P24 A;  1PVL A;  4Q7G A;  1LKF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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