4YL3A

Crystal structures of mpges-1 inhibitor complexes
Total Genus 63
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
63
sequence length
146
structure length
146
Chain Sequence
VMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal Structures of mPGES-1 Inhibitor Complexes Form a Basis for the Rational Design of Potent Analgesic and Anti-Inflammatory Therapeutics.
pubmed doi rcsb
molecule tags Isomerase/isomerase inhibitor
source organism Homo sapiens
molecule keywords Prostaglandin E synthase
total genus 63
structure length 146
sequence length 146
ec nomenclature ec 5.3.99.3: Prostaglandin-E synthase.
pdb deposition date 2015-03-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01124 MAPEG MAPEG family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.20.120.550 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Membrane associated eicosanoid/glutathione metabolism-like domain 4yl3A00
3PCVA 5BQGA 2Q7RA 4NTFA 3LEOA 3HKKA 4JC7A 4J7YA 2UUHA 2UUIA 4YL1A 2H8AA 5BQHA 4J7TA 5HV9A 4AL0A 4JCZA 4NTBA 4YL3A 5BQIA 5K0IA 2PNOA 4YK5A 4JRZA 3DWWA 4NTAA 4BPMA 4YL0A 4AL1A 4WABA 3B29A
chains in the Genus database with same CATH superfamily
4Z9IA 3AG1C 5T3WA 4PJNA 5HSWA 5DVWA 3TQOA 3MBGA 2QLAA 3EH2A 2YZSA 1GS9A 4IAQA 4IJJA 4J7YA 2L7AA 4JC7A 3CSKA 1SR2A 3GEHA 5AGFA 3G4XA 1KTMA 4EKWA 1CPRA 2R03A 4CS8C 4K7BA 3RFYA 4YT4A 5L0IA 4BEJA 1VLTA 4YT8A 2ETSA 1GQAA 2VCBA 3EGDA 1OCRC 5A6BD 2LSEA 1ZVZA 2VCCA 3U5SA 2PBEA 3FMSA 1QVXA 2YL0A 2OEVA 3DD7A 4MTGA 4YWQA 2EILC 1WOLA 4JRZA 1S05A 3LEVA 4WGYA 3EGDB 4FESA 3TK0A 2IXMA 2L9JA 1OCCC 1SZIA 2XM0A 3EGXA 3MFNA 4DOZA 2KYHA 3I4UA 1ZU5A 3JTLO 1OKKD 2Z15A 3JYHA 5JP7A 5EK0A 3ZWIA 4D4NA 4PJJA 4PJLA 4WJ0A 4U5HA 2FGYA 1G4WR 4MW3A 1HW2A 1L3PA 3LLKA 1Z7Qc 2CW0F 4CS9A 1D1CA 4CX9A 3EGXB 4OIOF 2WL8A 3AG3C 4ZLCA 2MWQA 5E3CA 2J45A 2ZPAA 4O6MA 2YL1A 4O6YA 1TFOB 1OW8A 2A6EF 1Q0GA 3NMJA 4G0HA 3U0CA 1TWCA 1BR1A 1SYQA 4DBQA 3C63A 3TOLA 1BZ4A 1D1BA 4LDQA 3LLIA 3DXJF 3NYJA 3DJNB 2OG2A 3UMHA 1O5HA 2WVOA 1MMNA 3EHNA 1NU7D 4MVZA 4PJMA 3EFOA 5IY5C 1KU2A 3RQGA 3T6BA 2XLWA 3N0TA 5B3SC 1Q0DA 2AU5A 3SZRA 4HEAJ 3SXKA 1LI7A 3RQEA 4A2NB 1A7DA 2Q7RA 4O7GA 3LS0A 3RW0A 2HSBA 4EBKA 1RJ9A 3L1MA 5KYYB 1U6HA 4ER9A 1LI5A 1JOGA 1T6QA 4C3EA 4HE8D 2YKZA 1VYKA 4MVOA 3HKKA 2XS8A 3HTKC 1OW7A 2X0CA 3W4YA 3IQ5A 1HE1A 4JURI 2DGJA 2QY9A 3TULA 1CGNA 1LIHA 3JCUQ 3PMRA 2EPMX 4LACB 1L7CA 1RJ9B 3U8PA 1V55C 1JR8A 4CBEA 4A4AA 2A1DD 5L0FA 1H9TA 2HV7A 3ZQYA 3ABLC 1ST6A 3E70C 1ZU4A 2YLGA 1BDJB 3FXHA 2HZ8A 1G5ZA 2XLMA 1E86A 4IRUA 2XL6A 3EPVA 3GWLA 4MVRA 5KYNA 2A0BA 4FAPB 4P6IC 256BA 1VLSA 1D0ZA 2J8WA 3Q6MA 4O6NA 3UMKA 1ZW2A 3TJ6A 5B1BC 4ULVA 3GM2A 4KNVA 3JZ0A 3B29A 2GFHA 1BBHA 2NUTA 3GWNA 2R25A 3X1OA 1D1AA 3K6BA 2X51A 1WATA 3EJNA 2L6GA 1H7IA 2DYSC 2NUTB 3UNGC 4XPYA 4UDVA 1B68A 4QI2A 3B0VC 3T6GB 3MX3A 2B0HA 5A6AA 1FR0A 3JRTA 3QTHA 3ZQVA 3US6A 4Q5SF 3NDBB 3M4CA 3U2LA 1FMVA 2W9YA 2EPOA 2P61A 1V54C 4EBJA 2D4UA 1NFOA 4BJ1A 2XRHA 4NY3A 1Z23A 1R4TA 3AG2C 1FMWA 2W45A 3NYMA 5DLJA 1QLEC 3EG9A 1ZZPA 3GM1A 4MQ9F 3OEOA 5D92A 4N06A 2R7OA 1RXQA 1Q0MA 5DQZA 3B71A 3A11A 2ZXWC 4W8PA 3HNLA 5JUAA 2WZLA 3EG9B 4GQHA 4XLNF 3W8IA 2CNWA 4ONSA 3EH1A 3I5PA 3U3FA 5AC4A 1RCPA 2VC9A 4OIPF 3DAFA 2GAQA 4AE4A 1OXBA 3UGPA 1A0BA 3ZSUA 2ZXPA 2GDCA 2A69F 1WN0A 4XLPF 1U89A 1NU9C 2R7RA 4CS7A 3DMDA 1OR3A 5EHHA 2A0UA 2W4MA 1I4ZA 5DS6A 2JX0A 1ORJA 2QUPA 1ORYA 4LDRA 5D91A 3NRHA 5E33A 1WTYA 2JPUA 5GPGB 5KYXA 4PFPA 3ABMC 2E87A 1FTSA 2OOCA 4DXWA 3J06A 1AVOB 3DJUB 2IYLD 2PP4A 1TWHA 4P9FA 1H6GA 2VCAA 1YVIA 5CI9A 1M56C 3GANA 1F1MA 4KNWA 5CIVA 2C03A 2LFFA 3M15A 3ABKC 4WGZA 2P7VA 2A6HF 2PX3A 2R05A 4J32B 2M4EA 1Q0FA 4U5CE 1E2XA 2J0WA 2WZFA 2H8AA 3KPHA 3C62A 3N2ZB 4BJ6C 4AX2A 1K40A 3KL4A 5HV9A 5T1DB 3C8ZA 4DRHB 3W8HA 2IXPA 4IWBA 4KC9A 5KYXB 1LS4A 1UG7A 2ZD9A 4U9EA 4XEVA 1M2VA 4AK9A 2CDQA 4IGGA 4YJWA 1T9KA 4C3DA 3FVYA 4I1OB 4LERA 2FAPB 3K33A 1M6TA 1TQGA 3RYLA 1YLMA 2QNLA 2XLEA 3U3BA 1E84A 1M2VB 3HNJA 3MYFA 4ANJA 2BC5A 2IOQA 3GODA 4BG0A 1J8MF 2G3VA 4MTOA 4IARA 5DQTA 1HMOA 1Q0KA 4MVUA 1Z3IX 4E18A 4DRJB 1J8YF 2Q9CA 3C8GA 1YZCA 4K0DA 4XEFA 1ZHTA 3UR3C 4MTFA 4MVMA 3JSZA 2V3CC 3RVYA 4JCZA 4JJFA 4OINF 1OW6A 3DM9B 2DI3A 2H7VC 3A9CA 4JVSA 2PF4E 4KI2A 3SXZA 4I1MA 2OJED 1OXKA 1PD0A 4U5EE 1C02A 2G3KA 1MMGA 2J7PA 4XPWA 3JT1A 3ZG1A 4CJOA 1EKYA 1HW1A 2D5RB 3HNIA 3Q7LA 4G78A 4OD5A 3S84A 4JEBA 1OCZC 1E85A 4G7ZF 4O79A 3S0XA 3IEEA 4NQFA 2I15A 3U8VA 1R5ID 2OKUA 2L81A 4GEHA 4H4KC 1ZHYA 3EFOB 1JRAA 3AGUA 1QKRA 2KW3C 3L8IA 5L0DA 1TWAA 2UUIA 5A6BA 3KMIA 3CAXA 4GYTA 3L8JA 4E7SA 1VK5A 3F46A 2CGEA 1D0YA 2NSFA 3H2VA 3TJ5A 1NFNA 2XSEA 3HNKA 3HLZA 1YAUO 2PX0A 4QI0A 4OIRF 3K1IC 1ZHZA 5L0HA 2R7TA 1YYXA 2R7VA 5DS4A 3RQFA 1M57C 1RMVA 1V4AA 2NPUA 2WB7A 4YL0A 4N4WA 2AP3A 2LIGA 2EIKC 2B0JA 5T3TA 1JMWA 3V5ZA 3F47A 4Z9HA 2VH3A 4DRIB 3CZ6A 4M63A 3LEOA 3RH3A 3VF0A 1K05A 1PCXA 2HJMA 3NMIA 2GA0A 3DE9A 3NG1A 1QSPA 4FX5A 3O10A 1ZW3A 4K1OA 2R7XA 4J30B 4PFOA 2BL2A 1XZPA 2EIMC 1GM5A 1NLXA 2QE9A 3QW1A 5E2QA 3LJBA 4BJ5C 3SXYA 3OWTA 4YT2A 3JRMO 4KBLA 1A7VA 1AUEA 1MNEA 2YL7A 5DS5A 4CSAC 1TFKB 1DOWA 2F22A 4JTCB 4YN0B 1CGOA 4BPMA 1A7EA 3T6JA 4MNDA 3S9OA 1OR2A 4G7HF 1H9GA 5COFA 1HY5A 3BEHA 2PFDA 1K04A 1QQ3A 1Z5ZA 1VMAA 3FHDA 3QVZA 4MW8A 1N1CA 3DZAA 1YZAA 1JPNA 4NC3A 2TMVP 2MHRA 5E3AA 1V74B 2IXOA 2XL8A 1UFBA 2IXNA 1MMAA 3VRCA 4BJ6A 1ORSC 2AWCA 2YVKA 2AVKA 2EPKX 3QVYA 4MVQA 4B6IA 2NUPA 1TR2A 2V26A 2J9VA 3DE8A 3LESA 1ZYRF 2HKVA 3GEIA 3IQCA 3K1HA 2XLOA 3L0IA 2KGOA 3O39A 4BEMJ 4J7TA 1Y4CA 3Q7GA 3ZTMA 3WG7C 4EBBA 1Z63A 2XM4A 2QTVA 4U5DE 1BR2A 1I4YA 4IAOA 2JD3A 5KYUA 4AE4B 4DVZA 5KYWA 1YYJA 1HE9A 1EQ1A 2XXAA 2HV6A 2EPLX 5TJ5E 1YDIA 2Q00A 2Q4FA 2OQMA 4PK4A 4L6RA 4C7OA 1SF8A 2Q9BA 1OCOC 3WAQA 3VM6A 2W4BA 4EIYA 5KYWB 4MVSA 4NTFA 1ZHWA 4CDYA 4LLCA 2HJ3A 2XS1A 1RKEA 1GGQA 2HUJA 4JE9A 4JTDB 4N6CA 5COMA 2VASA 5A69A 4U9DA 3GORA 4YL1A 2YLIA 1HMDA 2H7OA 3LUTB 3AOUA 3AQBA 4HFFB 1QPUA 3VYWA 3G50A 2G62A 1T5OA 2YQYA 3U9JA 5AC5A 3G4ZA 3T4RA 2LFDA 4LLEA 4ULWA 3EQLF 2VB6A 3B9QA 3LNMB 1LVKA 3M1CB 4Z9JA 2Y3HA 4EWCA 2LCHA 1E83A 4XTKA 1WGWA 3AQCA 3C18A 4IB4A 4JJGA 3V5XA 3AG4C 1YJGA 2LQGA 2GWWA 3S29A 3JSEO 1PD1A 4RD9A 5FZTA 3SYNA 2R7SA 4N6HA 1G8XA 2Q3TA 2P6VA 5BQGA 4E0HA 4CIPA 3MYIA 5L0CA 5JSLA 2KK1A 5FCLA 2RD9A 1APCA 2WVNA 4Q4ZF 4H54A 2OCCC 3PHF2 3C7JA 2YL3A 4JCHA 3H65A 4LDKA 5COGA 1XZQA 1IZMA 1XWJA 2R7WA 1VYIA 3DI5A 4JZAA 1VTMP 2OEXA 1RKCA 3K1IA 3DAGA 3EZHA 3LS1A 4AL0A 3AJMA 2J9BA 2HS5A 1BR4A 1A41A 1MQVA 2L6FA 1C17M 4YK5A 1NSGB 3C8GB 2HMZA 2P1AA 2Q9AA 3ZDLA 3O55A 3IHUA 4JW1A 1EI7A 4I3MA 2KC3A 4HFKB 4ZLDA 1DOVA 1Y6DA 3VAYA 2IBFA 5JT4A 5A6JA 1I5NA 3WODF 2O9XA 1JAFA 3EZIA 3NYLA 2KJGA 1MMDA 4CIHA 3ZVRA 2J9WA 1TWGA 2KQ9A 3K66A 1G4US 1O3UA 2J9UA 3KYIA 5L0GA 3GM3A 4CJGA 5A6KA 4BJ5A 3W2WA 1OQCA 3E9VA 3B0PA 3LNRA 3X2QC 4F4BA 1O87A 2XL4A 2WVQA 2DYRC 3FOOA 3RF3A 3ZIBA 4CSAA 5L3QA 1ZHXA 2CYDA 2ZXRA 1YA7O 2YRFA 3CEXA 2YHSA 3KYJA 4NTBA 4U5GA 3RVZA 2EPNA 5EGYA 4OIQF 4MS2A 5KYYA 1NG1A 3H2UA 1EA8A 3O6XA 4PR9A 5L3VA 1AEPA 4QDLA 3GEEA 1OKKA 1T01A 3ITFA 4CDVA 1FFTC 4E0IA 2J46A 2R9RB 3N24A 1MNDA 1NZEA 3MLGA 2R7QA 3PCVA 3T9OA 1IW7F 3U9MA 4CDAA 4PACA 1JPJA 3R2PA 3B0UX 3SEOA 4XEKA 3NMKA 2YEVA 2CNWD 2ICWG 1T6UA 2HSQA 2DB4A 3ZTZA 2NSGA 4CS9C 5B1AC 1YA9A 4JKVA 4DVYP 3NKEA 3QZCA 2CCYA 2HFIA 3V5YA 5L0JA 3M79A 3S90A 1U0BB 4XWJA 1VOMA 4YL3A 1S7ZA 1LE4A 1LE2A 3QMKA 3TD7A 2H7BA 2PNOA 1PV3A 4W8KA 2KSFA 3EHMA 1VB5A 4NTAA 4C3BA 2Y39A 4RBNA 2XLHA 5B3IA 2Y3GA 3RIPA 1FFHA 3R7CA 4AL1A 5JVEA 4WABA 1FAPB 2M64A 3LAYA 4U5FE 1M2OA 3IQ6A 2Y3DA 3HJCA 3W2VA 3S28A 5JRAA 4EHPA 4Q7CA 4RDAA 2BE5F 1C03A 3U2MA 2Y3BA 2ASRA 5F28E 1LM3B 3ECSA 4YT5A 2LD6A 3SNHA 3IQTA 3FOPA 4XPXA 3ATPA 3WHNA 2KNHA 2Y69C 2UUHA 3SP1A 3OA1A 2EINC 1CPQA 4XQ1A 2IM8A 3FDQA 2OU6A 4DBRA 5BQHA 2AWYA 2EIJC 3S27A 3JYYA 4E7ZA 3PDMP 3K7DA 4OD4A 2XLDA 1FNTc 2L6HA 1D0XA 5K0IA 2NUPB 1LPEA 5F5FA 2YWAA 2MYSA 4EUKB 3UMIA 1QZXA 2A68F 3IPMO 2R02A 2J0XA 2LK4A 2I8BA 2YLDA 4BJTA 1W2WA 3NKDA 2LP4A 4JIOA 3BRJA 4D4XA 5KYUB 3ASNC 1YARO 2NG1A 2P0NA 3L34A 4JEAA 2OJQA 4NCQA 5CI8A 1WASA 4CS8A 5BUOA 1LS1A 5JLIA 1T6IA 3FAPB 2XXAB 3CQZA 4R32A 3QW0A 4X0RA 1CGME 2RSEB 4C7OB 5JS5A 3KKBA 3FAJA 4U5BE 3KH2A 5F5HA 4E17A 2XLVA 1WWPA 3TOMA 4G7OF 3C8GD 2HMQA 3V7OA 1RKEB 2ZXOA 3ZC4A 3DKAA 3DM5A 3I5QA 5BQIA 1TKNA 4FWVA 1Z6AA 1NBBA 3RKOF 4JTAB 4P9TA 1KNYA 3UGOA 1LKXA 3SXMA 1SMYF 3DWWA 4DJ9A 3POVA 2R7UA 2C04A 3Q6NA 2J7PD 3M4BA 4I44A 3ASOC 3AGTA 2WZGA 2FFHA
chains in the Genus database with same CATH topology
3PCVA 5BQGA 2Q7RA 4NTFA 3LEOA 3HKKA 4JC7A 4J7YA 2UUHA 2UUIA 4YL1A 2H8AA 5BQHA 4J7TA 5HV9A 4AL0A 4JCZA 4NTBA 4YL3A 5BQIA 5K0IA 2PNOA 4YK5A 4JRZA 3DWWA 4NTAA 4BPMA 4YL0A 4AL1A 4WABA 3B29A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PCV A;  5BQG A;  2Q7R A;  4NTF A;  3LEO A;  3HKK A;  4JC7 A;  4J7Y A;  2UUH A;  2UUI A;  4YL1 A;  2H8A A;  5BQH A;  4J7T A;  5HV9 A;  4AL0 A;  4JCZ A;  4NTB A;  4YL3 A;  5BQI A;  5K0I A;  2PNO A;  4YK5 A;  4JRZ A;  3DWW A;  4NTA A;  4BPM A;  4YL0 A;  4AL1 A;  4WAB A;  3B29 A; 
#chains in the Genus database with same CATH topology
 4Z9I A;  3AG1 C;  5T3W A;  4PJN A;  5HSW A;  5DVW A;  3TQO A;  3MBG A;  2QLA A;  3EH2 A;  2YZS A;  1GS9 A;  4IAQ A;  4IJJ A;  4J7Y A;  2L7A A;  4JC7 A;  3CSK A;  1SR2 A;  3GEH A;  5AGF A;  3G4X A;  1KTM A;  4EKW A;  1CPR A;  2R03 A;  4CS8 C;  4K7B A;  3RFY A;  4YT4 A;  5L0I A;  4BEJ A;  1VLT A;  4YT8 A;  2ETS A;  1GQA A;  2VCB A;  3EGD A;  1OCR C;  5A6B D;  2LSE A;  1ZVZ A;  2VCC A;  3U5S A;  2PBE A;  3FMS A;  1QVX A;  2YL0 A;  2OEV A;  3DD7 A;  4MTG A;  4YWQ A;  2EIL C;  1WOL A;  4JRZ A;  1S05 A;  3LEV A;  4WGY A;  3EGD B;  4FES A;  3TK0 A;  2IXM A;  2L9J A;  1OCC C;  1SZI A;  2XM0 A;  3EGX A;  3MFN A;  4DOZ A;  2KYH A;  3I4U A;  1ZU5 A;  3JTL O;  1OKK D;  2Z15 A;  3JYH A;  5JP7 A;  5EK0 A;  3ZWI A;  4D4N A;  4PJJ A;  4PJL A;  4WJ0 A;  4U5H A;  2FGY A;  1G4W R;  4MW3 A;  1HW2 A;  1L3P A;  3LLK A;  1Z7Q c;  2CW0 F;  4CS9 A;  1D1C A;  4CX9 A;  3EGX B;  4OIO F;  2WL8 A;  3AG3 C;  4ZLC A;  2MWQ A;  5E3C A;  2J45 A;  2ZPA A;  4O6M A;  2YL1 A;  4O6Y A;  1TFO B;  1OW8 A;  2A6E F;  1Q0G A;  3NMJ A;  4G0H A;  3U0C A;  1TWC A;  1BR1 A;  1SYQ A;  4DBQ A;  3C63 A;  3TOL A;  1BZ4 A;  1D1B A;  4LDQ A;  3LLI A;  3DXJ F;  3NYJ A;  3DJN B;  2OG2 A;  3UMH A;  1O5H A;  2WVO A;  1MMN A;  3EHN A;  1NU7 D;  4MVZ A;  4PJM A;  3EFO A;  5IY5 C;  1KU2 A;  3RQG A;  3T6B A;  2XLW A;  3N0T A;  5B3S C;  1Q0D A;  2AU5 A;  3SZR A;  4HEA J;  3SXK A;  1LI7 A;  3RQE A;  4A2N B;  1A7D A;  2Q7R A;  4O7G A;  3LS0 A;  3RW0 A;  2HSB A;  4EBK A;  1RJ9 A;  3L1M A;  5KYY B;  1U6H A;  4ER9 A;  1LI5 A;  1JOG A;  1T6Q A;  4C3E A;  4HE8 D;  2YKZ A;  1VYK A;  4MVO A;  3HKK A;  2XS8 A;  3HTK C;  1OW7 A;  2X0C A;  3W4Y A;  3IQ5 A;  1HE1 A;  4JUR I;  2DGJ A;  2QY9 A;  3TUL A;  1CGN A;  1LIH A;  3JCU Q;  3PMR A;  2EPM X;  4LAC B;  1L7C A;  1RJ9 B;  3U8P A;  1V55 C;  1JR8 A;  4CBE A;  4A4A A;  2A1D D;  5L0F A;  1H9T A;  2HV7 A;  3ZQY A;  3ABL C;  1ST6 A;  3E70 C;  1ZU4 A;  2YLG A;  1BDJ B;  3FXH A;  2HZ8 A;  1G5Z A;  2XLM A;  1E86 A;  4IRU A;  2XL6 A;  3EPV A;  3GWL A;  4MVR A;  5KYN A;  2A0B A;  4FAP B;  4P6I C;  256B A;  1VLS A;  1D0Z A;  2J8W A;  3Q6M A;  4O6N A;  3UMK A;  1ZW2 A;  3TJ6 A;  5B1B C;  4ULV A;  3GM2 A;  4KNV A;  3JZ0 A;  3B29 A;  2GFH A;  1BBH A;  2NUT A;  3GWN A;  2R25 A;  3X1O A;  1D1A A;  3K6B A;  2X51 A;  1WAT A;  3EJN A;  2L6G A;  1H7I A;  2DYS C;  2NUT B;  3UNG C;  4XPY A;  4UDV A;  1B68 A;  4QI2 A;  3B0V C;  3T6G B;  3MX3 A;  2B0H A;  5A6A A;  1FR0 A;  3JRT A;  3QTH A;  3ZQV A;  3US6 A;  4Q5S F;  3NDB B;  3M4C A;  3U2L A;  1FMV A;  2W9Y A;  2EPO A;  2P61 A;  1V54 C;  4EBJ A;  2D4U A;  1NFO A;  4BJ1 A;  2XRH A;  4NY3 A;  1Z23 A;  1R4T A;  3AG2 C;  1FMW A;  2W45 A;  3NYM A;  5DLJ A;  1QLE C;  3EG9 A;  1ZZP A;  3GM1 A;  4MQ9 F;  3OEO A;  5D92 A;  4N06 A;  2R7O A;  1RXQ A;  1Q0M A;  5DQZ A;  3B71 A;  3A11 A;  2ZXW C;  4W8P A;  3HNL A;  5JUA A;  2WZL A;  3EG9 B;  4GQH A;  4XLN F;  3W8I A;  2CNW A;  4ONS A;  3EH1 A;  3I5P A;  3U3F A;  5AC4 A;  1RCP A;  2VC9 A;  4OIP F;  3DAF A;  2GAQ A;  4AE4 A;  1OXB A;  3UGP A;  1A0B A;  3ZSU A;  2ZXP A;  2GDC A;  2A69 F;  1WN0 A;  4XLP F;  1U89 A;  1NU9 C;  2R7R A;  4CS7 A;  3DMD A;  1OR3 A;  5EHH A;  2A0U A;  2W4M A;  1I4Z A;  5DS6 A;  2JX0 A;  1ORJ A;  2QUP A;  1ORY A;  4LDR A;  5D91 A;  3NRH A;  5E33 A;  1WTY A;  2JPU A;  5GPG B;  5KYX A;  4PFP A;  3ABM C;  2E87 A;  1FTS A;  2OOC A;  4DXW A;  3J06 A;  1AVO B;  3DJU B;  2IYL D;  2PP4 A;  1TWH A;  4P9F A;  1H6G A;  2VCA A;  1YVI A;  5CI9 A;  1M56 C;  3GAN A;  1F1M A;  4KNW A;  5CIV A;  2C03 A;  2LFF A;  3M15 A;  3ABK C;  4WGZ A;  2P7V A;  2A6H F;  2PX3 A;  2R05 A;  4J32 B;  2M4E A;  1Q0F A;  4U5C E;  1E2X A;  2J0W A;  2WZF A;  2H8A A;  3KPH A;  3C62 A;  3N2Z B;  4BJ6 C;  4AX2 A;  1K40 A;  3KL4 A;  5HV9 A;  5T1D B;  3C8Z A;  4DRH B;  3W8H A;  2IXP A;  4IWB A;  4KC9 A;  5KYX B;  1LS4 A;  1UG7 A;  2ZD9 A;  4U9E A;  4XEV A;  1M2V A;  4AK9 A;  2CDQ A;  4IGG A;  4YJW A;  1T9K A;  4C3D A;  3FVY A;  4I1O B;  4LER A;  2FAP B;  3K33 A;  1M6T A;  1TQG A;  3RYL A;  1YLM A;  2QNL A;  2XLE A;  3U3B A;  1E84 A;  1M2V B;  3HNJ A;  3MYF A;  4ANJ A;  2BC5 A;  2IOQ A;  3GOD A;  4BG0 A;  1J8M F;  2G3V A;  4MTO A;  4IAR A;  5DQT A;  1HMO A;  1Q0K A;  4MVU A;  1Z3I X;  4E18 A;  4DRJ B;  1J8Y F;  2Q9C A;  3C8G A;  1YZC A;  4K0D A;  4XEF A;  1ZHT A;  3UR3 C;  4MTF A;  4MVM A;  3JSZ A;  2V3C C;  3RVY A;  4JCZ A;  4JJF A;  4OIN F;  1OW6 A;  3DM9 B;  2DI3 A;  2H7V C;  3A9C A;  4JVS A;  2PF4 E;  4KI2 A;  3SXZ A;  4I1M A;  2OJE D;  1OXK A;  1PD0 A;  4U5E E;  1C02 A;  2G3K A;  1MMG A;  2J7P A;  4XPW A;  3JT1 A;  3ZG1 A;  4CJO A;  1EKY A;  1HW1 A;  2D5R B;  3HNI A;  3Q7L A;  4G78 A;  4OD5 A;  3S84 A;  4JEB A;  1OCZ C;  1E85 A;  4G7Z F;  4O79 A;  3S0X A;  3IEE A;  4NQF A;  2I15 A;  3U8V A;  1R5I D;  2OKU A;  2L81 A;  4GEH A;  4H4K C;  1ZHY A;  3EFO B;  1JRA A;  3AGU A;  1QKR A;  2KW3 C;  3L8I A;  5L0D A;  1TWA A;  2UUI A;  5A6B A;  3KMI A;  3CAX A;  4GYT A;  3L8J A;  4E7S A;  1VK5 A;  3F46 A;  2CGE A;  1D0Y A;  2NSF A;  3H2V A;  3TJ5 A;  1NFN A;  2XSE A;  3HNK A;  3HLZ A;  1YAU O;  2PX0 A;  4QI0 A;  4OIR F;  3K1I C;  1ZHZ A;  5L0H A;  2R7T A;  1YYX A;  2R7V A;  5DS4 A;  3RQF A;  1M57 C;  1RMV A;  1V4A A;  2NPU A;  2WB7 A;  4YL0 A;  4N4W A;  2AP3 A;  2LIG A;  2EIK C;  2B0J A;  5T3T A;  1JMW A;  3V5Z A;  3F47 A;  4Z9H A;  2VH3 A;  4DRI B;  3CZ6 A;  4M63 A;  3LEO A;  3RH3 A;  3VF0 A;  1K05 A;  1PCX A;  2HJM A;  3NMI A;  2GA0 A;  3DE9 A;  3NG1 A;  1QSP A;  4FX5 A;  3O10 A;  1ZW3 A;  4K1O A;  2R7X A;  4J30 B;  4PFO A;  2BL2 A;  1XZP A;  2EIM C;  1GM5 A;  1NLX A;  2QE9 A;  3QW1 A;  5E2Q A;  3LJB A;  4BJ5 C;  3SXY A;  3OWT A;  4YT2 A;  3JRM O;  4KBL A;  1A7V A;  1AUE A;  1MNE A;  2YL7 A;  5DS5 A;  4CSA C;  1TFK B;  1DOW A;  2F22 A;  4JTC B;  4YN0 B;  1CGO A;  4BPM A;  1A7E A;  3T6J A;  4MND A;  3S9O A;  1OR2 A;  4G7H F;  1H9G A;  5COF A;  1HY5 A;  3BEH A;  2PFD A;  1K04 A;  1QQ3 A;  1Z5Z A;  1VMA A;  3FHD A;  3QVZ A;  4MW8 A;  1N1C A;  3DZA A;  1YZA A;  1JPN A;  4NC3 A;  2TMV P;  2MHR A;  5E3A A;  1V74 B;  2IXO A;  2XL8 A;  1UFB A;  2IXN A;  1MMA A;  3VRC A;  4BJ6 A;  1ORS C;  2AWC A;  2YVK A;  2AVK A;  2EPK X;  3QVY A;  4MVQ A;  4B6I A;  2NUP A;  1TR2 A;  2V26 A;  2J9V A;  3DE8 A;  3LES A;  1ZYR F;  2HKV A;  3GEI A;  3IQC A;  3K1H A;  2XLO A;  3L0I A;  2KGO A;  3O39 A;  4BEM J;  4J7T A;  1Y4C A;  3Q7G A;  3ZTM A;  3WG7 C;  4EBB A;  1Z63 A;  2XM4 A;  2QTV A;  4U5D E;  1BR2 A;  1I4Y A;  4IAO A;  2JD3 A;  5KYU A;  4AE4 B;  4DVZ A;  5KYW A;  1YYJ A;  1HE9 A;  1EQ1 A;  2XXA A;  2HV6 A;  2EPL X;  5TJ5 E;  1YDI A;  2Q00 A;  2Q4F A;  2OQM A;  4PK4 A;  4L6R A;  4C7O A;  1SF8 A;  2Q9B A;  1OCO C;  3WAQ A;  3VM6 A;  2W4B A;  4EIY A;  5KYW B;  4MVS A;  4NTF A;  1ZHW A;  4CDY A;  4LLC A;  2HJ3 A;  2XS1 A;  1RKE A;  1GGQ A;  2HUJ A;  4JE9 A;  4JTD B;  4N6C A;  5COM A;  2VAS A;  5A69 A;  4U9D A;  3GOR A;  4YL1 A;  2YLI A;  1HMD A;  2H7O A;  3LUT B;  3AOU A;  3AQB A;  4HFF B;  1QPU A;  3VYW A;  3G50 A;  2G62 A;  1T5O A;  2YQY A;  3U9J A;  5AC5 A;  3G4Z A;  3T4R A;  2LFD A;  4LLE A;  4ULW A;  3EQL F;  2VB6 A;  3B9Q A;  3LNM B;  1LVK A;  3M1C B;  4Z9J A;  2Y3H A;  4EWC A;  2LCH A;  1E83 A;  4XTK A;  1WGW A;  3AQC A;  3C18 A;  4IB4 A;  4JJG A;  3V5X A;  3AG4 C;  1YJG A;  2LQG A;  2GWW A;  3S29 A;  3JSE O;  1PD1 A;  4RD9 A;  5FZT A;  3SYN A;  2R7S A;  4N6H A;  1G8X A;  2Q3T A;  2P6V A;  5BQG A;  4E0H A;  4CIP A;  3MYI A;  5L0C A;  5JSL A;  2KK1 A;  5FCL A;  2RD9 A;  1APC A;  2WVN A;  4Q4Z F;  4H54 A;  2OCC C;  3PHF 2;  3C7J A;  2YL3 A;  4JCH A;  3H65 A;  4LDK A;  5COG A;  1XZQ A;  1IZM A;  1XWJ A;  2R7W A;  1VYI A;  3DI5 A;  4JZA A;  1VTM P;  2OEX A;  1RKC A;  3K1I A;  3DAG A;  3EZH A;  3LS1 A;  4AL0 A;  3AJM A;  2J9B A;  2HS5 A;  1BR4 A;  1A41 A;  1MQV A;  2L6F A;  1C17 M;  4YK5 A;  1NSG B;  3C8G B;  2HMZ A;  2P1A A;  2Q9A A;  3ZDL A;  3O55 A;  3IHU A;  4JW1 A;  1EI7 A;  4I3M A;  2KC3 A;  4HFK B;  4ZLD A;  1DOV A;  1Y6D A;  3VAY A;  2IBF A;  5JT4 A;  5A6J A;  1I5N A;  3WOD F;  2O9X A;  1JAF A;  3EZI A;  3NYL A;  2KJG A;  1MMD A;  4CIH A;  3ZVR A;  2J9W A;  1TWG A;  2KQ9 A;  3K66 A;  1G4U S;  1O3U A;  2J9U A;  3KYI A;  5L0G A;  3GM3 A;  4CJG A;  5A6K A;  4BJ5 A;  3W2W A;  1OQC A;  3E9V A;  3B0P A;  3LNR A;  3X2Q C;  4F4B A;  1O87 A;  2XL4 A;  2WVQ A;  2DYR C;  3FOO A;  3RF3 A;  3ZIB A;  4CSA A;  5L3Q A;  1ZHX A;  2CYD A;  2ZXR A;  1YA7 O;  2YRF A;  3CEX A;  2YHS A;  3KYJ A;  4NTB A;  4U5G A;  3RVZ A;  2EPN A;  5EGY A;  4OIQ F;  4MS2 A;  5KYY A;  1NG1 A;  3H2U A;  1EA8 A;  3O6X A;  4PR9 A;  5L3V A;  1AEP A;  4QDL A;  3GEE A;  1OKK A;  1T01 A;  3ITF A;  4CDV A;  1FFT C;  4E0I A;  2J46 A;  2R9R B;  3N24 A;  1MND A;  1NZE A;  3MLG A;  2R7Q A;  3PCV A;  3T9O A;  1IW7 F;  3U9M A;  4CDA A;  4PAC A;  1JPJ A;  3R2P A;  3B0U X;  3SEO A;  4XEK A;  3NMK A;  2YEV A;  2CNW D;  2ICW G;  1T6U A;  2HSQ A;  2DB4 A;  3ZTZ A;  2NSG A;  4CS9 C;  5B1A C;  1YA9 A;  4JKV A;  4DVY P;  3NKE A;  3QZC A;  2CCY A;  2HFI A;  3V5Y A;  5L0J A;  3M79 A;  3S90 A;  1U0B B;  4XWJ A;  1VOM A;  4YL3 A;  1S7Z A;  1LE4 A;  1LE2 A;  3QMK A;  3TD7 A;  2H7B A;  2PNO A;  1PV3 A;  4W8K A;  2KSF A;  3EHM A;  1VB5 A;  4NTA A;  4C3B A;  2Y39 A;  4RBN A;  2XLH A;  5B3I A;  2Y3G A;  3RIP A;  1FFH A;  3R7C A;  4AL1 A;  5JVE A;  4WAB A;  1FAP B;  2M64 A;  3LAY A;  4U5F E;  1M2O A;  3IQ6 A;  2Y3D A;  3HJC A;  3W2V A;  3S28 A;  5JRA A;  4EHP A;  4Q7C A;  4RDA A;  2BE5 F;  1C03 A;  3U2M A;  2Y3B A;  2ASR A;  5F28 E;  1LM3 B;  3ECS A;  4YT5 A;  2LD6 A;  3SNH A;  3IQT A;  3FOP A;  4XPX A;  3ATP A;  3WHN A;  2KNH A;  2Y69 C;  2UUH A;  3SP1 A;  3OA1 A;  2EIN C;  1CPQ A;  4XQ1 A;  2IM8 A;  3FDQ A;  2OU6 A;  4DBR A;  5BQH A;  2AWY A;  2EIJ C;  3S27 A;  3JYY A;  4E7Z A;  3PDM P;  3K7D A;  4OD4 A;  2XLD A;  1FNT c;  2L6H A;  1D0X A;  5K0I A;  2NUP B;  1LPE A;  5F5F A;  2YWA A;  2MYS A;  4EUK B;  3UMI A;  1QZX A;  2A68 F;  3IPM O;  2R02 A;  2J0X A;  2LK4 A;  2I8B A;  2YLD A;  4BJT A;  1W2W A;  3NKD A;  2LP4 A;  4JIO A;  3BRJ A;  4D4X A;  5KYU B;  3ASN C;  1YAR O;  2NG1 A;  2P0N A;  3L34 A;  4JEA A;  2OJQ A;  4NCQ A;  5CI8 A;  1WAS A;  4CS8 A;  5BUO A;  1LS1 A;  5JLI A;  1T6I A;  3FAP B;  2XXA B;  3CQZ A;  4R32 A;  3QW0 A;  4X0R A;  1CGM E;  2RSE B;  4C7O B;  5JS5 A;  3KKB A;  3FAJ A;  4U5B E;  3KH2 A;  5F5H A;  4E17 A;  2XLV A;  1WWP A;  3TOM A;  4G7O F;  3C8G D;  2HMQ A;  3V7O A;  1RKE B;  2ZXO A;  3ZC4 A;  3DKA A;  3DM5 A;  3I5Q A;  5BQI A;  1TKN A;  4FWV A;  1Z6A A;  1NBB A;  3RKO F;  4JTA B;  4P9T A;  1KNY A;  3UGO A;  1LKX A;  3SXM A;  1SMY F;  3DWW A;  4DJ9 A;  3POV A;  2R7U A;  2C04 A;  3Q6N A;  2J7P D;  3M4B A;  4I44 A;  3ASO C;  3AGT A;  2WZG A;  2FFH A; 
#chains in the Genus database with same CATH homology
 3PCV A;  5BQG A;  2Q7R A;  4NTF A;  3LEO A;  3HKK A;  4JC7 A;  4J7Y A;  2UUH A;  2UUI A;  4YL1 A;  2H8A A;  5BQH A;  4J7T A;  5HV9 A;  4AL0 A;  4JCZ A;  4NTB A;  4YL3 A;  5BQI A;  5K0I A;  2PNO A;  4YK5 A;  4JRZ A;  3DWW A;  4NTA A;  4BPM A;  4YL0 A;  4AL1 A;  4WAB A;  3B29 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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