4YPWA

Crystal structure of trmd, a m1g37 trna methyltransferase with sam-competitive compounds
Total Genus 67
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
249
structure length
238
Chain Sequence
GSHMWIGVISLFPEMFKAITEFGVTGRAVKHNLLKVECWNPRDFTFDKHKTVDDRPYGGGPGMLMMVQPLRDAIHTAKAAAGEGAKVIYLSPQGRKLDQGGVTELAQNQKLILVCGRYEGIDERLIQTEIDEEWSIGDYVLTGGELPAMTLIDAVARFIPGVLGDGLLDCPHYTRPEVLEGLTVPPVLMSGHHEEIRKWRLKQSLQRTWLRRPELLEGLALTDEQRKLLKEAQAEHNS
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of TrmD, a M1G37 tRNA Methyltransferase with SAM-competitive compounds
rcsb
molecule tags Transferase/transferase inhibitor
source organism Haemophilus influenzae (strain atcc 51907 / dsm 11121 / kw20 / rd)
molecule keywords tRNA (guanine-N(1)-)-methyltransferase
total genus 67
structure length 238
sequence length 249
ec nomenclature ec 2.1.1.228: tRNA (guanine(37)-N(1))-methyltransferase.
pdb deposition date 2015-03-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF01746 tRNA_m1G_MT tRNA (Guanine-1)-methyltransferase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.1270.20 Mainly Alpha Orthogonal Bundle Trp Operon Repressor; Chain A tRNA(m1g37)methyltransferase, domain 2 4ypwA02
3.40.1280.10 Alpha Beta 3-Layer(aba) Sandwich Alpha/beta knot Alpha/beta knot 4ypwA01
4YQLA 1K3RA 4FAKA 4J3CA 4YQQA 3OIJA 2Z0YA 4MCBA 5D9FA 1Z85A 3ILKA 4YQGA 3AXZA 3QUVA 3N4KA 3AIAA 3GYQA 3L8UA 1X7OA 3ONPA 5GMBA 4YQ1A 4IG6A 4KGNA 3IC6A 1UAKA 4RG1A 4H3YA 4YQ3A 4XBOA 4YQJA 3KTYA 2QWVA 3BBHA 3BBEA 1ZJRA 4PZKA 4YQ6A 1V6ZA 1P9PA 2QMMA 3AI9X 4YQ2A 4YQCA 1NXZA 3N4JA 4YVGA 2V3JA 4YPWA 4YQ0A 4JAKA 4YVKA 1GZ0A 4YQKA 4YQ9A 1NS5A 2O3AA 1X7PA 4L69A 4CNFA 3KNUA 1VHYA 4YQDA 5FAIA 5CO4A 3OINA 1VH0A 2EGVA 4KDZA 4YQSA 1UALA 3E5YA 4YVIA 1MXIA 3NK7A 4X3MA 4X3LA 4YQIA 4YVJA 4YPYA 3DCMX 2HA8A 3IEFA 1UAJA 1IPAA 3O7BA 4YQAA 4JALA 4YQ7A 3OIIA 3BBDA 3NK6A 2CX8A 4YPZA 4CNDA 1J85A 2EGWA 1UAMA 4MCDA 4YQ4A 5GMCA 1OY5A 2I6DA 5GM8A 4YQOA 4YQ5A 4YVHA 4YQNA 1TO0A 4YQPA 4MCCA 4E8BA 4CNEA 4CNGA 3KW2A 3KY7A 4YQRA 4YQBA 4YQ8A 4YPXA 2V3KA 4H3ZA 2YY8A 4YQTA 1VHKA 1O6DA 1V2XA
chains in the Genus database with same CATH superfamily
4YQLA 1K3RA 4FAKA 4J3CA 2XDIA 4YQQA 3OIJA 2Z0YA 4MCBA 5D9FA 1TRRA 1Z85A 3ILKA 4YQGA 3AXZA 3QUVA 3N4KA 4JWHA 3AIAA 3GYQA 3KORA 3L8UA 1RCSA 1X7OA 3ONPA 5GMBA 4YQ1A 4IG6A 4KGNA 3IC6A 1UAKA 4RG1A 4H3YA 4YQ3A 4XBOA 4YQJA 3KTYA 2QWVA 3BBHA 3BBEA 1ZJRA 4PZKA 4YQ6A 1V6ZA 1P9PA 2QMMA 3AI9X 4YQ2A 4YQCA 1NXZA 3N4JA 4YVGA 2V3JA 4YPWA 4YQ0A 4JAKA 4YVKA 1GZ0A 4YQKA 4FMWA 4YQ9A 1NS5A 2O3AA 1X7PA 4L69A 4CNFA 3KNUA 1VHYA 4YQDA 5FAIA 5CO4A 3OINA 1VH0A 2EGVA 4KDZA 4YQSA 1TROA 1UALA 3E5YA 1WRPR 4YVIA 1MXIA 3FRWA 3NK7A 4X3LA 4X3MA 4YQIA 3WRPA 4YVJA 4YPYA 3DCMX 2HA8A 3IEFA 1UAJA 1IPAA 3O7BA 4YQAA 4JALA 4YQ7A 3OIIA 3BBDA 3NK6A 2CX8A 4JWGA 4YPZA 4CNDA 1J85A 4JWFA 2EGWA 1UAMA 4MCDA 4YQ4A 1MI7R 5GMCA 1OY5A 2I6DA 5GM8A 1WRSR 4YQOA 4YQ5A 1CO0A 4YVHA 4YQNA 1TO0A 4YQPA 2OZ9R 4MCCA 4E8BA 4CNEA 4JWJA 1ZT9A 4CNGA 3G1CA 1JHGA 3KW2A 3KY7A 1WRTR 3SSXN 4YQRA 4YQBA 4YQ8A 4YPXA 2V3KA 3SSWN 4H3ZA 2YY8A 4YQTA 1VHKA 1O6DA 1V2XA
chains in the Genus database with same CATH topology
4YQLA 1K3RA 4FAKA 4J3CA 4YQQA 3OIJA 2Z0YA 4MCBA 5D9FA 1Z85A 3ILKA 4YQGA 3AXZA 3QUVA 3N4KA 4JWHA 3AIAA 3GYQA 3L8UA 1X7OA 3ONPA 5GMBA 4YQ1A 4IG6A 4KGNA 3IC6A 1UAKA 4RG1A 4H3YA 4YQ3A 4XBOA 4YQJA 3KTYA 2QWVA 3BBHA 3BBEA 1ZJRA 4PZKA 4YQ6A 1V6ZA 1P9PA 2QMMA 3AI9X 4YQ2A 4YQCA 1NXZA 3N4JA 4YVGA 2V3JA 4YPWA 4YQ0A 4JAKA 4YVKA 1GZ0A 4YQKA 4FMWA 4YQ9A 1NS5A 2O3AA 1X7PA 4L69A 4CNFA 3KNUA 1VHYA 4YQDA 5FAIA 5CO4A 3OINA 1VH0A 2EGVA 4KDZA 4YQSA 1UALA 3E5YA 4YVIA 1MXIA 3NK7A 4X3MA 4X3LA 4YQIA 4YVJA 4YPYA 3DCMX 2HA8A 3IEFA 1UAJA 1IPAA 3O7BA 4YQAA 4JALA 4YQ7A 3OIIA 3BBDA 3NK6A 2CX8A 4JWGA 4YPZA 4CNDA 1J85A 4JWFA 2EGWA 1UAMA 4MCDA 4YQ4A 5GMCA 1OY5A 2I6DA 5GM8A 4YQOA 4YQ5A 4YVHA 4YQNA 1TO0A 4YQPA 4MCCA 4E8BA 4CNEA 4JWJA 4CNGA 3KW2A 3KY7A 4YQRA 4YQBA 4YQ8A 4YPXA 2V3KA 4H3ZA 2YY8A 4YQTA 1VHKA 1O6DA 1V2XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YQL A;  1K3R A;  4FAK A;  4J3C A;  4YQQ A;  3OIJ A;  2Z0Y A;  4MCB A;  5D9F A;  1Z85 A;  3ILK A;  4YQG A;  3AXZ A;  3QUV A;  3N4K A;  3AIA A;  3GYQ A;  3L8U A;  1X7O A;  3ONP A;  5GMB A;  4YQ1 A;  4IG6 A;  4KGN A;  3IC6 A;  1UAK A;  4RG1 A;  4H3Y A;  4YQ3 A;  4XBO A;  4YQJ A;  3KTY A;  2QWV A;  3BBH A;  3BBE A;  1ZJR A;  4PZK A;  4YQ6 A;  1V6Z A;  1P9P A;  2QMM A;  3AI9 X;  4YQ2 A;  4YQC A;  1NXZ A;  3N4J A;  4YVG A;  2V3J A;  4YPW A;  4YQ0 A;  4JAK A;  4YVK A;  1GZ0 A;  4YQK A;  4YQ9 A;  1NS5 A;  2O3A A;  1X7P A;  4L69 A;  4CNF A;  3KNU A;  1VHY A;  4YQD A;  5FAI A;  5CO4 A;  3OIN A;  1VH0 A;  2EGV A;  4KDZ A;  4YQS A;  1UAL A;  3E5Y A;  4YVI A;  1MXI A;  3NK7 A;  4X3M A;  4X3L A;  4YQI A;  4YVJ A;  4YPY A;  3DCM X;  2HA8 A;  3IEF A;  1UAJ A;  1IPA A;  3O7B A;  4YQA A;  4JAL A;  4YQ7 A;  3OII A;  3BBD A;  3NK6 A;  2CX8 A;  4YPZ A;  4CND A;  1J85 A;  2EGW A;  1UAM A;  4MCD A;  4YQ4 A;  5GMC A;  1OY5 A;  2I6D A;  5GM8 A;  4YQO A;  4YQ5 A;  4YVH A;  4YQN A;  1TO0 A;  4YQP A;  4MCC A;  4E8B A;  4CNE A;  4CNG A;  3KW2 A;  3KY7 A;  4YQR A;  4YQB A;  4YQ8 A;  4YPX A;  2V3K A;  4H3Z A;  2YY8 A;  4YQT A;  1VHK A;  1O6D A;  1V2X A; 
#chains in the Genus database with same CATH topology
 4YQL A;  1K3R A;  4FAK A;  4J3C A;  2XDI A;  4YQQ A;  3OIJ A;  2Z0Y A;  4MCB A;  5D9F A;  1TRR A;  1Z85 A;  3ILK A;  4YQG A;  3AXZ A;  3QUV A;  3N4K A;  4JWH A;  3AIA A;  3GYQ A;  3KOR A;  3L8U A;  1RCS A;  1X7O A;  3ONP A;  5GMB A;  4YQ1 A;  4IG6 A;  4KGN A;  3IC6 A;  1UAK A;  4RG1 A;  4H3Y A;  4YQ3 A;  4XBO A;  4YQJ A;  3KTY A;  2QWV A;  3BBH A;  3BBE A;  1ZJR A;  4PZK A;  4YQ6 A;  1V6Z A;  1P9P A;  2QMM A;  3AI9 X;  4YQ2 A;  4YQC A;  1NXZ A;  3N4J A;  4YVG A;  2V3J A;  4YPW A;  4YQ0 A;  4JAK A;  4YVK A;  1GZ0 A;  4YQK A;  4FMW A;  4YQ9 A;  1NS5 A;  2O3A A;  1X7P A;  4L69 A;  4CNF A;  3KNU A;  1VHY A;  4YQD A;  5FAI A;  5CO4 A;  3OIN A;  1VH0 A;  2EGV A;  4KDZ A;  4YQS A;  1TRO A;  1UAL A;  3E5Y A;  1WRP R;  4YVI A;  1MXI A;  3FRW A;  3NK7 A;  4X3L A;  4X3M A;  4YQI A;  3WRP A;  4YVJ A;  4YPY A;  3DCM X;  2HA8 A;  3IEF A;  1UAJ A;  1IPA A;  3O7B A;  4YQA A;  4JAL A;  4YQ7 A;  3OII A;  3BBD A;  3NK6 A;  2CX8 A;  4JWG A;  4YPZ A;  4CND A;  1J85 A;  4JWF A;  2EGW A;  1UAM A;  4MCD A;  4YQ4 A;  1MI7 R;  5GMC A;  1OY5 A;  2I6D A;  5GM8 A;  1WRS R;  4YQO A;  4YQ5 A;  1CO0 A;  4YVH A;  4YQN A;  1TO0 A;  4YQP A;  2OZ9 R;  4MCC A;  4E8B A;  4CNE A;  4JWJ A;  1ZT9 A;  4CNG A;  3G1C A;  1JHG A;  3KW2 A;  3KY7 A;  1WRT R;  3SSX N;  4YQR A;  4YQB A;  4YQ8 A;  4YPX A;  2V3K A;  3SSW N;  4H3Z A;  2YY8 A;  4YQT A;  1VHK A;  1O6D A;  1V2X A; 
#chains in the Genus database with same CATH homology
 4YQL A;  1K3R A;  4FAK A;  4J3C A;  4YQQ A;  3OIJ A;  2Z0Y A;  4MCB A;  5D9F A;  1Z85 A;  3ILK A;  4YQG A;  3AXZ A;  3QUV A;  3N4K A;  4JWH A;  3AIA A;  3GYQ A;  3L8U A;  1X7O A;  3ONP A;  5GMB A;  4YQ1 A;  4IG6 A;  4KGN A;  3IC6 A;  1UAK A;  4RG1 A;  4H3Y A;  4YQ3 A;  4XBO A;  4YQJ A;  3KTY A;  2QWV A;  3BBH A;  3BBE A;  1ZJR A;  4PZK A;  4YQ6 A;  1V6Z A;  1P9P A;  2QMM A;  3AI9 X;  4YQ2 A;  4YQC A;  1NXZ A;  3N4J A;  4YVG A;  2V3J A;  4YPW A;  4YQ0 A;  4JAK A;  4YVK A;  1GZ0 A;  4YQK A;  4FMW A;  4YQ9 A;  1NS5 A;  2O3A A;  1X7P A;  4L69 A;  4CNF A;  3KNU A;  1VHY A;  4YQD A;  5FAI A;  5CO4 A;  3OIN A;  1VH0 A;  2EGV A;  4KDZ A;  4YQS A;  1UAL A;  3E5Y A;  4YVI A;  1MXI A;  3NK7 A;  4X3M A;  4X3L A;  4YQI A;  4YVJ A;  4YPY A;  3DCM X;  2HA8 A;  3IEF A;  1UAJ A;  1IPA A;  3O7B A;  4YQA A;  4JAL A;  4YQ7 A;  3OII A;  3BBD A;  3NK6 A;  2CX8 A;  4JWG A;  4YPZ A;  4CND A;  1J85 A;  4JWF A;  2EGW A;  1UAM A;  4MCD A;  4YQ4 A;  5GMC A;  1OY5 A;  2I6D A;  5GM8 A;  4YQO A;  4YQ5 A;  4YVH A;  4YQN A;  1TO0 A;  4YQP A;  4MCC A;  4E8B A;  4CNE A;  4JWJ A;  4CNG A;  3KW2 A;  3KY7 A;  4YQR A;  4YQB A;  4YQ8 A;  4YPX A;  2V3K A;  4H3Z A;  2YY8 A;  4YQT A;  1VHK A;  1O6D A;  1V2X A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...